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https://www.readbyqxmd.com/read/30335146/evidence-of-polygenic-adaptation-to-high-altitude-from-tibetan-and-sherpa-genomes
#1
Guido A Gnecchi-Ruscone, Paolo Abondio, Sara De Fanti, Stefania Sarno, Mingma G Sherpa, Phurba T Sherpa, Giorgio Marinelli, Luca Natali, Marco Di Marcello, Davide Peluzzi, Donata Luiselli, Davide Pettener, Marco Sazzini
Although Tibetans and Sherpa present several physiological adjustments evolved to cope with selective pressures imposed by the high altitude environment, especially hypobaric hypoxia, few selective sweeps at a limited number of hypoxia related genes were confirmed by multiple genomic studies. Nevertheless, variants at these loci were found to be associated only with downregulation of the erythropoietic cascade, which represents an indirect aspect of the considered adaptive phenotype. Accordingly, the genetic basis of Tibetan/Sherpa adaptive traits remains to be fully elucidated, in part due to limitations of selection scans implemented so far and mostly relying on the hard sweep model...
October 18, 2018: Genome Biology and Evolution
https://www.readbyqxmd.com/read/30332987/temperature-controlled-thermophilic-bacterial-communities-in-hot-springs-of-western-sichuan-china
#2
Jie Tang, Yuanmei Liang, Dong Jiang, Liheng Li, Yifan Luo, Md Mahfuzur R Shah, Maurycy Daroch
BACKGROUND: Ganzi Prefecture in Western China is situated geographically at the transition regions between Tibetan Plateau and Sichuan Basin in a highly tectonically active boundary area between the India and Eurasia plates. The region hosts various hot springs that span a wide range of temperature from 30 to 98 °C and are located at high altitude (up to 4200 m above sea level) in the region of large geothermal anomalies and active Xianshuihe slip-fault that has been active since Holocene...
October 17, 2018: BMC Microbiology
https://www.readbyqxmd.com/read/30328721/immunoexpression-of-aquaporins-1-2-3-and-4-in-kidney-of-yak-bos-grunniens-on-the-qinghai-tibetan-plateau
#3
Y P Ding, H S Yu, J L Wang, B P Shao
Aquaporins (AQP) 1, 2, 3 and 4 belong to the aquaporin water channel family and play an important role in urine concentration by reabsorption of water from renal tubule fluid. Renal AQPs have not been reported in the yak (Bos grunniens), which resides in the Qinghai Tibetan Plateau. We investigated AQPs 1-4 expressions in the kidneys of Yak using immunohistochemical staining. AQP1 was expressed mainly in the basolateral and apical membranes of the proximal tubules and descending thin limb of the loop of Henle...
October 17, 2018: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/30326458/changes-in-the-soil-microbial-communities-of-alpine-steppe-at-qinghai-tibetan-plateau-under-different-degradation-levels
#4
Heng Zhou, Degang Zhang, Zhehao Jiang, Peng Sun, Hailong Xiao, Yuxing Wu, Jiangang Chen
The alpine steppe at Qinghai-Tibetan Plateau is an important area for conserving water source and grassland productivity; however, knowledge about the microbial community structure and function and the risk to human health due to alpine plant-soil ecosystems is limited. Thus, we used prediction methods, such as Tax4Fun, and performed a metagenome pre-study using 16S rRNA sequencing reads for a small scale survey of the microbial communities at degraded alpine steppes (i.e., non-degraded (ND), lightly degraded (LD), moderately degraded (MD), heavily degraded (HD), and extremely degraded (ED) steppes) by Illumina high-throughput sequencing technology...
October 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/30325035/warming-affects-foliar-fungal-diseases-more-than-precipitation-in-a-tibetan-alpine-meadow
#5
Xiang Liu, Zhiyuan Ma, Marc W Cadotte, Fei Chen, Jin-Sheng He, Shurong Zhou
The effects of global change on semi-natural and agro-ecosystem functioning have been studied extensively. However, less well understood is how global change will influence fungal diseases, especially in a natural ecosystem. We use data from a 6-yr factorial experiment with warming (simulated using infrared heaters) and altered precipitation treatments in a natural Tibetan alpine meadow ecosystem, from which we tested global change effects on foliar fungal diseases at the population and community levels, and evaluated the importance of direct effects of the treatments and community-mediated (indirect) effects (through changes in plant community composition and competence) of global change on community pathogen load...
October 16, 2018: New Phytologist
https://www.readbyqxmd.com/read/30323800/precise-fecal-microbiome-of-the-herbivorous-tibetan-antelope-inhabiting-high-altitude-alpine-plateau
#6
Xiangning Bai, Shan Lu, Jing Yang, Dong Jin, Ji Pu, Sara Díaz Moyá, Yanwen Xiong, Ramon Rossello-Mora, Jianguo Xu
The metataxonomic approach combining 16S rRNA gene amplicon sequencing using the PacBio Technology with the application of the operational phylogenetic unit (OPU) approach, has been used to analyze the fecal microbial composition of the high-altitude and herbivorous Tibetan antelopes. The fecal samples of the antelope were collected in Hoh Xil National Nature Reserve, at an altitude over 4500 m, the largest depopulated zone in Qinghai-Tibetan Plateau, China, where non-native animals or humans may experience life-threatening acute mountain sickness...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/30323705/characterization-of-the-complete-mitochondrial-genome-of-parabreviscolexniepini-xi-et-al-2018-cestoda-caryophyllidea
#7
Bing-Wen Xi, Dong Zhang, Wen-Xiang Li, Bao-Juan Yang, Jun Xie
Parabreviscolexniepini is a recently described caryophyllidean monozoic tapeworm from schizothoracine fish on the Tibetan Plateau. In the present study, the complete mitochondrial genome of P.niepini is determined for the first time. The mitogenome is 15,034 bp in length with an A+T content of 59.6%, and consists of 12 protein-encoding genes, 22 tRNA genes, two rRNA genes, and two non-coding regions. The secondary structure of tRNAs exhibit the conventional cloverleaf structure, except for trnS1 (AGN) and trnR , which lack DHU arms...
2018: ZooKeys
https://www.readbyqxmd.com/read/30321727/bacterial-community-changes-in-a-glacial-fed-tibetan-lake-are-correlated-with-glacial-melting
#8
Keshao Liu, Yongqin Liu, Bo-Ping Han, Baiqing Xu, Liping Zhu, Jianting Ju, Nianzhi Jiao, Jinbo Xiong
Climate change-induced glacial melting is a global phenomenon. The effects of climate change-induced melting on the microbial ecology in different glacial-fed aquatic systems have been well illuminated, but the resolution of seasonal dynamics was still limited. Here, we studied bacterial community composition and diversity in a glacial-fed Tibetan lake, Lake Ranwu, to elucidate how glacial-fed aquatic ecosystems respond to the seasonal glacial melting. Obvious seasonal variations of bacterial dominant groups were found in Lake Ranwu and inlet rivers...
October 9, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/30319668/climatic-changes-and-orogeneses-in-the-late-miocene-of-eurasia-the-main-triggers-of-an-expansion-at-a-continental-scale
#9
Dong-Rui Jia, Igor V Bartish
Migrations from the Qinghai-Tibetan Plateau (QTP) to other temperate regions represent one of the main biogeographical patterns for the Northern Hemisphere. However, the ages and routes of these migrations are largely not known. We aimed to reconstruct a well-resolved and dated phylogeny of Hippophae L. (Elaeagnaceae) and test hypothesis of a westward migration of this plant out of the QTP across Eurasian mountains in the Miocene. We produced two data matrices of five chloroplast DNA (cpDNA) and five nuclear DNA markers for all distinct taxa of Hippophae ...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/30317779/-clinical-analysis-of-1-058-cases-hepatic-cirrhosis-of-tibetan-nationality
#10
Y Ren, Y H Yang, J Wang
No abstract text is available yet for this article.
July 20, 2018: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/30315220/influence-of-tibetan-plateau-snow-cover-on-east-asian-atmospheric-circulation-at-medium-range-time-scales
#11
Wenkai Li, Weidong Guo, Bo Qiu, Yongkang Xue, Pang-Chi Hsu, Jiangfeng Wei
The responses of atmospheric variability to Tibetan Plateau (TP) snow cover (TPSC) at seasonal, interannual and decadal time scales have been extensively investigated. However, the atmospheric response to faster subseasonal variability of TPSC has been largely ignored. Here, we show that the subseasonal variability of TPSC, as revealed by daily data, is closely related to the subsequent East Asian atmospheric circulation at medium-range time scales (approximately 3-8 days later) during wintertime. TPSC acts as an elevated cooling source in the middle troposphere during wintertime and rapidly modulates the land surface thermal conditions over the TP...
October 12, 2018: Nature Communications
https://www.readbyqxmd.com/read/30313709/preliminary-taxonomical-investigation-of-soil-enchytraeids-clitellata-enchytraeidae-from-south-region-of-tibet-china
#12
Yajing Lu, Zhicai Xie, Junqian Zhang
The biodiversity in the Tibetan region is still poorly known, particularly for its soil organisms. Here, we describe eleven enchytraeid species based on several taxonomical surveys in 2015-2016, from some soil localities in south region of the Tibet, China. All are firstly recorded in this region; seven species (Fridericia ratzeli sensu stricto, F. peregrinabunda, F. cusanica, F. bretscheri, Buchholzia sp., Enchytraeus buchholzi and Henlea sp.) are new records for China.
October 4, 2018: Zootaxa
https://www.readbyqxmd.com/read/30309357/the-prevalence-of-hyperuricemia-and-its-correlates-in-ganzi-tibetan-autonomous-prefecture-sichuan-province-china
#13
Xin Zhang, Qingtao Meng, Jiayue Feng, Hang Liao, Rufeng Shi, Di Shi, Lachu Renqian, Zeren Langtai, Yuanbin Diao, Xiaoping Chen
BACKGROUND: Hyperuricemia is a common and serious public health problem. There has been no broad epidemiological survey of hyperuricemia in China, especially in Tibetan area. This study was therefore investigated the prevalence of hyperuricemia and its correlated factors among people aged 18-85 years in Ganzi Tibetan Autonomous Prefecture, Sichuan Province, China. METHODS: We carried out a cross-sectional study among 3093 participants in Ganzi Tibetan Autonomous Prefecture using questionnaires in face-to-face interviews, anthropometric measurements and biochemical tests...
October 12, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/30308022/dissolved-organic-carbon-in-glaciers-of-the-southeastern-tibetan-plateau-insights-into-concentrations-and-possible-sources
#14
Yulan Zhang, Shichang Kang, Gang Li, Tanguang Gao, Pengfei Chen, Xiaofei Li, Yajun Liu, Zhaofu Hu, Shiwei Sun, Junming Guo, Kun Wang, Xintong Chen, Mika Sillanpää
Dissolved organic carbon (DOC) released from glaciers has an important role in the biogeochemistry of glacial ecosystems. This study focuses on DOC from glaciers of the southeastern Tibetan Plateau, where glaciers are experiencing rapid shrinkage. We found that concentrations of DOC in snowpits (0.16±0.054 μg g-1), aged snow (0.16±0.048 μg g-1), and bare ice (0.18±0.082 μg g-1) were similar across the southeastern Tibetan Plateau, but were slightly lower than those in other glaciers on the Tibetan Plateau...
2018: PloS One
https://www.readbyqxmd.com/read/30304864/-scabiosa-genus-a-rich-source-of-bioactive-metabolites
#15
REVIEW
Diana C G A Pinto, Naima Rahmouni, Noureddine Beghidja, Artur M S Silva
The genus Scabiosa (family Caprifoliaceae) is considered large (618 scientific plant names of species) although only 62 have accepted Latin binominal names. The majority of the Scabiosa species are widely distributed in the Mediterranean region and some Scabiosa species are used in traditional medicine systems. For instance, Scabiosa columbaria L. is used traditionally against diphtheria while S. comosa Fisch. Ex Roem. and Schult. is used in Mongolian and Tibetan traditional medical settings to treat liver diseases...
October 9, 2018: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/30302803/a-comparison-of-prenatal-muscle-transcriptome-and-proteome-profiles-between-pigs-with-divergent-growth-phenotypes
#16
Peng Shang, Zhixiu Wang, Yangzom Chamba, Bo Zhang, Hao Zhang, Changxin Wu
The growth of pigs is an important economic trait that involves multiple genes and coordinated regulatory mechanisms. The growth rate and potential of skeletal muscles are largely decided by embryonic myofiber development. Tibetan pig (TP) that is a mini-type breed has a divergent phenotype in growth rate and adult body weight with Wujin pig (WJ) and large White pig (LW). In the current study, the transcriptome (using RNA-seq) and proteome (using the isobaric tag for relative and absolute quantification [iTRAQ]) data from the prenatal muscle tissues were analyzed to identify the genes related to postnatal growth rate and growth potential in pigs...
October 9, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/30298083/spatial-patterns-of-leaf-carbon-nitrogen-and-phosphorus-stoichiometry-of-aquatic-macrophytes-in-the-arid-zone-of-northwestern-china
#17
Xusheng Gong, Zhiyan Xu, Wei Lu, Yuqing Tian, Yaheng Liu, Zhengxiang Wang, Can Dai, Jinghui Zhao, Zhongqiang Li
Ecological stoichiometry is a powerful indicator for understanding the adaptation of plants to environment. However, understanding of stoichiometric characteristics of leaf carbon (C%), nitrogen (N%), and phosphorus (P%) for aquatic macrophytes remains limited. In this study, 707 samples from 146 sites were collected to study the variations in leaf C%, N%, and P%, and tried to explore how different environmental conditions affect leaf C, N, and P stoichiometry. Results showed that the mean values of leaf C%, N%, P%, and N:P ratios were 39...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/30298021/transcriptome-analysis-provides-insights-into-the-adaptive-responses-to-hypoxia-of-a-schizothoracine-fish-gymnocypris-eckloni
#18
Delin Qi, Yan Chao, Rongrong Wu, Mingzhe Xia, Qichang Chen, Zhiqin Zheng
The schizothoracine fish endemic to the Qinghai-Tibetan Plateau are comparatively well adapted to aquatic environments with low oxygen partial pressures. However, few studies have used transcriptomic profiling to investigate the adaptive responses of schizothoracine fish tissues to hypoxic stress. This study compared the transcriptomes of Gymnocypris eckloni subjected to 72 h of hypoxia (Dissolved oxygen, DO = 3.0 ± 0.1 mg/L) to those of G. eckloni under normoxia (DO = 8.4 ± 0.1 mg/L). To identify the potential genes and pathways activated in response to hypoxic stress, we collected muscle, liver, brain, heart, and blood samples from normoxic and hypoxic fish for RNA-Seq analysis...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/30297768/gene-coexpression-network-analysis-combined-with-metabonomics-reveals-the-resistance-responses-to-powdery-mildew-in-tibetan-hulless-barley
#19
Hongjun Yuan, Xingquan Zeng, Qiaofeng Yang, Qijun Xu, Yulin Wang, Dunzhu Jabu, Zha Sang, Nyima Tashi
Powdery mildew is a fungal disease that represents a ubiquitous threat to crop plants. Transcriptomic and metabolomic analyses were used to identify molecular and physiological changes in Tibetan hulless barley in response to powdery mildew. There were 3418 genes and 405 metabolites differentially expressed between the complete resistance cultivar G7 and the sensitive cultivar Z13. Weighted gene coexpression network analysis was carried out, and the differentially expressed genes were enriched in five and four major network modules in G7 and Z13, respectively...
October 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30296774/response-of-plant-production-to-growing-non-growing-season-asymmetric-warming-in-an-alpine-meadow-of-the-northern-tibetan-plateau
#20
Gang Fu, Hao Rui Zhang, Wei Sun
A field growing/non-growing season asymmetric warming experiment (C: control, i.e., no warming in the entire year; GLNG: growing season warming lower than non-growing season warming; GHNG: growing season warming higher than non-growing season warming) was conducted in an alpine meadow of the Northern Tibetan Plateau in early June 2015. The effects of growing/non-growing season asymmetric warming on the normalized difference vegetation index (NDVI), soil adjusted vegetation index (SAVI), aboveground biomass (AGB) and gross primary production (GPP) in 2015-2017 were examined...
October 3, 2018: Science of the Total Environment
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