Hafiz Ishfaq Ahmad, Sammina Mahmood, Mubashar Hassan, Muhammad Sajid, Irfan Ahmed, Borhan Shokrollahi, Abid Hussain Shahzad, Shaista Abbas, Sanan Raza, Komal Khan, Sayyed Aun Muhammad, Dalia Fouad, Farid S Ataya, Zhengtian Li
High-altitude environments present formidable challenges for survival and reproduction, with organisms facing limited oxygen availability and scarce nutrient resources. The yak (Bos grunniens), indigenous to the Tibetan Plateau, has notably adapted to these extreme conditions. This study delves into the genomic basis of the yak's adaptation, focusing on the positive selection acting on genes involved in nutrient assimilation pathways. Employing techniques in comparative genomics and molecular evolutionary analyses, we selected genes in the yak that show signs of positive selection associated with nutrient metabolism, absorption, and transport...
March 7, 2024: Scientific Reports