keyword
https://read.qxmd.com/read/38520902/targeted-and-untargeted-metabolomics-reveals-meat-quality-in-grazing-yak-during-different-phenology-periods-on-the-qinghai-tibetan-plateau
#1
JOURNAL ARTICLE
Tongqing Guo, Qian Zhang, Xungang Wang, Xianli Xu, Yalin Wang, Lin Wei, Na Li, Hongjin Liu, Linyong Hu, Na Zhao, Shixiao Xu
Yak meat is more popular among consumers because of its high nutritional value, but little attention has been paid to its meat quality, which is affected by different phenology periods grass. We hypothesized that seasonal variations in grass composition influenced the ruminal bacteria community, and eventually affected the meat quality of yaks. This study aims to investigate the relationship of meat quality in grazing yak as well as the key rumen bacteria using targeted and untargeted metabolomics and 16S rRNA during different phenology periods...
February 27, 2024: Food Chemistry
https://read.qxmd.com/read/38512994/impact-of-annual-community-directed-treatment-with-ivermectin-on-the-incidence-of-epilepsy-in-mvolo-a-two-year-prospective-study
#2
JOURNAL ARTICLE
Luís-Jorge Amaral, Stephen Raimon Jada, Aimee Kemayou Ndjanfa, Jane Y Carter, Gasim Abd-Elfarag, Samuel Okaro, Makoy Yibi Logora, Yak Yak Bol, Thomson Lakwo, Joseph N Siewe Fodjo, Robert Colebunders
OBJECTIVES: The potential impact of cumulative community-directed treatment with ivermectin (CDTI) on epilepsy epidemiology in Mvolo County, South Sudan, an onchocerciasis-endemic area with high epilepsy prevalence, was investigated. Annual CDTI was introduced in 2002 in Mvolo, with interruptions in 2016 and 2020. METHODS: Comprehensive house-to-house surveys in Mvolo (June 2020 and 2022) identified cases of epilepsy, including probable nodding syndrome (pNS). Community workers screened households in selected sites for suspected epilepsy, and medical doctors confirmed the diagnosis and determined the year of seizure onset...
March 21, 2024: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/38503100/heme-oxygenase-1-ho1-regulates-autophagy-and-apoptosis-via-the-pi3k-akt-mtor-signaling-pathway-of-yak-sertoli-cells
#3
JOURNAL ARTICLE
Qiu Yan, Qi Wang, Jinghong Nan, Tingting Chen, Juntao Wang, Yong Zhang, Ligang Yuan
Successful male reproduction depends on healthy testes. Autophagy has been confirmed to be active during many cellular events associated with the testes. It is not only crucial for testicular spermatogenesis but is also an essential regulatory mechanism for Sertoli cell (SCs) ectoplasmic specialization integrity and normal function of the blood-testis-barrier. Hypoxic stress induces oxidative damage, apoptosis, and autophagy, negatively affecting the male reproductive system. Cryptorchidism is a common condition associated with infertility...
March 13, 2024: Theriogenology
https://read.qxmd.com/read/38487638/suspected-cutaneous-anthrax-in-a-yak-herder-in-a-highland-community-in-bhutan-2023-a-case-report
#4
Ugyen Chophel, Sangay Dorji, Kuenga Sonam, Thinley Dorji
This case presents cutaneous anthrax in yak herder from a central highland community in Bhutan. We highlight the clinical presentation, diagnosis and management of the case in a resource-limited setting, and the public health response through the One Health approach.
March 2024: Clinical Case Reports
https://read.qxmd.com/read/38484587/defb114-protein-enhances-host-resistance-to-fungal-infection-through-the-nod1-2-atg16l1-nf-%C3%AE%C2%BAb-signaling-pathway
#5
JOURNAL ARTICLE
Jingyun Chen, Qundi Mei, Li Wang, Yong Wei
The overuse of antibiotics has led to the enhanced resistance of many pathogenic bacteria, posing a threat to human health. Therefore, there is a need to develop green and safe alternatives to antibiotics. Beta-defensins play a crucial role in host defense against pathogens and have multifunctional properties, exerting key roles in innate and adaptive immunity, as well as non-immune processes. In this study, a 210 bp long cDNA sequence of yak DEFB114 gene was amplified and successfully expressed in a prokaryotic system...
March 4, 2024: Bioorganic Chemistry
https://read.qxmd.com/read/38473080/genome-wide-transcriptome-profiling-reveals-the-mechanisms-underlying-hepatic-metabolism-under-different-raising-systems-in-yak
#6
JOURNAL ARTICLE
Mengfan Zhang, Xita Zha, Xiaoming Ma, Yongfu La, Xian Guo, Min Chu, Pengjia Bao, Ping Yan, Xiaoyun Wu, Chunnian Liang
Yak meat is nutritionally superior to beef cattle but has a low fat content and is slow-growing. The liver plays a crucial role in lipid metabolism, and in order to determine whether different feeding modes affect lipid metabolism in yaks and how it is regulated, we employed RNA sequencing (RNA-seq) technology to analyze the genome-wide differential gene expression in the liver of yaks maintained under different raising systems. A total of 1663 differentially expressed genes (DEGs) were identified (|log2FC| ≥ 0 and p -value ≤ 0...
February 23, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38472894/association-between-single-nucleotide-polymorphisms-of-prkd1-and-kcnq3-gene-and-milk-quality-traits-in-gannan-yak-bos-grunniens
#7
JOURNAL ARTICLE
Xiaoyong Ma, Guowu Yang, Juanxiang Zhang, Rong Ma, Jinwei Shen, Fen Feng, Daoning Yu, Chun Huang, Xiaoming Ma, Yongfu La, Xiaoyun Wu, Xian Guo, Min Chu, Ping Yan, Chunnian Liang
Protein kinase D1 (PRKD1) functions primarily in normal mammary cells, and the potassium voltage-gated channel subfamily Q member 3 ( KCNQ3 ) gene plays an important role in controlling membrane potential and neuronal excitability, it has been found that this particular gene is linked to the percentage of milk fat in dairy cows. The purpose of this study was to investigate the relationship between nucleotide polymorphisms (SNPs) of PRKD1 and KCNQ3 genes and the milk quality of Gannan yak and to find molecular marker sites that may be used for milk quality breeding of Gannan yak...
March 2, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38466638/potential-effects-of-no-induced-hypoxia-inducible-factor-1%C3%AE-on-yak-meat-tenderness-during-post-mortem-aging
#8
JOURNAL ARTICLE
Nan Sun, Zhuo Wang, Xijin Zhu, Siyi Tan, Rende Song, Wenying Shi, Ling Han, Qunli Yu
The objective of this study was to investigate the mechanism underlying nitric oxide (NO)-induced hypoxia-inducible factor-1α (HIF-1α) and its impact on yak muscle tenderness during post-mortem aging. The Longissimus thoracis et lumborum (LTL) muscle of yak were incubated at 4 °C for 0, 3, 6, 9, 12, 24, and 72 h after treatment with 0.9% saline, NO activator, or a combination of the NO activator and an HIF-1α inhibitor. Results indicated that elevated NO levels could increase HIF-1α transcription to achieve stable expression of HIF-1α protein ( P < 0...
March 11, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38466437/leading-report-of-molecular-prevalence-of-tick-borne-anaplasma-marginale-and-theileria-ovis-in-yaks-bos-grunniens-from-pakistan
#9
JOURNAL ARTICLE
Muqaddas Nawaz, Rehmat Ullah, Zia Ur Rehman, Muhammad Naeem, Afshan Khan, Mohammed Bourhia, Muhammad Mudassir Sohail, Takbir Ali, Adil Khan, Tanveer Hussain, Furhan Iqbal
Domestic yak (Bos grunniens) is an economically important feature of the mountainous region of Gilgit-Baltistan in Pakistan where agriculture is restricted and yaks play multiple roles which includes being a source of milk, meat, hides, fuel and power. However little is known about the parasitic infections in Pakistani yaks. Aim of this research was to report the prevalence and genetic diversity of protozoa parasite (Theileria ovis, 18 S rDNA gene was targeted) and an obligate bacterium (Anaplasma marginale, msp-1 gene was amplified) in the blood that was sampled from 202 yaks collected from four districts in Gilgit-Baltistan during January 2023 till January 2024...
March 11, 2024: Archives of Microbiology
https://read.qxmd.com/read/38453987/genomic-insights-into-yak-bos-grunniens-adaptations-for-nutrient-assimilation-in-high-altitudes
#10
JOURNAL ARTICLE
Hafiz Ishfaq Ahmad, Sammina Mahmood, Mubashar Hassan, Muhammad Sajid, Irfan Ahmed, Borhan Shokrollahi, Abid Hussain Shahzad, Shaista Abbas, Sanan Raza, Komal Khan, Sayyed Aun Muhammad, Dalia Fouad, Farid S Ataya, Zhengtian Li
High-altitude environments present formidable challenges for survival and reproduction, with organisms facing limited oxygen availability and scarce nutrient resources. The yak (Bos grunniens), indigenous to the Tibetan Plateau, has notably adapted to these extreme conditions. This study delves into the genomic basis of the yak's adaptation, focusing on the positive selection acting on genes involved in nutrient assimilation pathways. Employing techniques in comparative genomics and molecular evolutionary analyses, we selected genes in the yak that show signs of positive selection associated with nutrient metabolism, absorption, and transport...
March 7, 2024: Scientific Reports
https://read.qxmd.com/read/38453548/rinderpest-a-disease-of-the-past-and-a-present-threat
#11
REVIEW
Mariana Marrana, Muhammad Javed Arshed, Mo Salman
Rinderpest is a highly contagious viral disease that affects ungulates such as cattle, buffalo, yak, and various wildlife species, leading to significant morbidity and mortality. The global eradication of rinderpest was successfully accomplished in 2011 through extensive vaccination efforts. Today, safeguarding against the re-emergence of rinderpest in animal populations is paramount. The Food and Agriculture Organization of the United Nations and the World Organization for Animal Health are entrusted through a series of resolutions with the responsibility to prevent the re-emergence of rinderpest in animals...
March 6, 2024: Veterinary Clinics of North America. Food Animal Practice
https://read.qxmd.com/read/38439875/sodium-acetate-and-sodium-butyrate-attenuate-diarrhea-in-yak-calves-by-regulating-gut-microbiota-and-metabolites
#12
JOURNAL ARTICLE
Qinghui Kong, Xiushuang Chen, Yang Liu, Farah Ali, Asif Idrees, Farid Shokry Ataya, Zhenda Shang, Kun Li
Diarrhea is a severe issue in calves that causes fertility problems and economic issues worldwide. Sodium acetate/sodium butyrate (SA/SB) alleviates diarrhea in mice; however, little information is available about the preventive effect of SA/SB on diarrheic yak calves living on the Tibet plateau. Yak calves (n = 19) of age ≥4 months and weight 37 ± 2 Kg were randomly divided into control (C, n = 10) and supplement groups (S, n = 9). Yaks belonging to the supplement group were given sodium butyrate (10 g/kg) and sodium acetate (5 g/kg) for 28 days, along with normal feed, seasonal grasses, pasture, and water...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38432684/profiling-and-functional-analysis-of-circular-rnas-in-yaks-intramuscular-fat
#13
JOURNAL ARTICLE
Quyangangmao Su, Sayed Haidar Abbas Raza, Zhanhong Gao, Fengshuo Zhang, ZhenLing Wu, QiuRong Ji, TingLi He, Bandar Hamad Aloufi, Ahmed A El-Mansi, Mamdouh Eldesoqui, Deema Kamal Sabir, Linsheng Gui
Circular RNAs (circRNAs) are a new class of endogenous RNA regulating gene expression. However, the regulatory mechanisms of lipid metabolism in yaks involved in circRNAs remain poorly understood. The IMF plays a crucial role in the quality of yak meat, to greatly improve the meat quality. In this study, the fatty acid profiles of yak IMF were determined and circRNAs were sequenced. The results showed that the total of polyunsaturated fatty acid (PUFA) content of adult yak muscle was significantly higher than that in yak calves (p < 0...
March 3, 2024: Journal of Animal Physiology and Animal Nutrition
https://read.qxmd.com/read/38426365/multi-disciplinary-diabetic-limb-salvage-programme-in-octogenarians-with-diabetic-foot-ulcers-is-not-futile-an-observational-study-with-historical-controls
#14
JOURNAL ARTICLE
Lixia Ge, Jiashen Zhao, Matthew Tan, Elaine Tan, Huiling Liew, Enming Yong, Jeremy Hoe, Claris Shi, Dexter Yak Seng Chan, Gary Yee Ang, Joseph Antonio Molina, Yan Sun, Wai Han Hoi, Sadhana Chandraskear, Zhiwen Joseph Lo
This study evaluated the effectiveness of a multi-disciplinary diabetic limb salvage programme in improving clinical outcomes and optimising healthcare utilisation in 406 patients aged ≥80 years with diabetic foot ulcers (DFUs), compared to 2392 younger patients enrolled from June 2020 to June 2021 and against 1716 historical controls using one-to-one propensity score matching. Results showed that elderly programme patients had lower odds of amputation-free survival (odds ratio: 0.64, 95% CI: 0...
March 2024: International Wound Journal
https://read.qxmd.com/read/38423309/large-herbivore-grazing-accelerates-litter-decomposition-in-terrestrial-ecosystems
#15
JOURNAL ARTICLE
Ao Jiang, Tserang Donko Mipam, Luhuai Jing, Zhe Li, Tao Li, Jianquan Liu, Liming Tian
Plant litter decomposition is critical for carbon and nutrient cycling globally. However, the effect of large herbivore grazing on litter decomposition and its mechanisms remain less explored. Here, 1203 paired observations and 381 independent experiments were analyzed to determine how litter decomposition and nutrient cycling respond to changes in grazing intensity. Grazing significantly increased litter decomposition rate by 14.08 % and litter carbon release by 5.03 %, and this effect was observed in grasslands and croplands but not in forests...
February 27, 2024: Science of the Total Environment
https://read.qxmd.com/read/38419639/ruminal-microbiota-and-muscle-metabolome-characteristics-of-tibetan-plateau-yaks-fed-different-dietary-protein-levels
#16
JOURNAL ARTICLE
Kaiyue Pang, Jianmei Wang, Shatuo Chai, Yingkui Yang, Xun Wang, Shujie Liu, Cheng Ding, ShuXiang Wang
INTRODUCTION: The dietary protein level plays a crucial role in maintaining the equilibrium of rumen microbiota in yaks. To explore the association between dietary protein levels, rumen microbiota, and muscle metabolites, we examined the rumen microbiome and muscle metabolome characteristics in yaks subjected to varying dietary protein levels. METHODS: In this study, 36 yaks were randomly assigned to three groups ( n = 12 per group): low dietary protein group (LP, 12% protein concentration), medium dietary protein group (MP, 14% protein concentration), and high dietary protein group (HP, 16% protein concentration)...
2024: Frontiers in Microbiology
https://read.qxmd.com/read/38406648/-will-i-be-able-to-be-myself-or-will-i-be-forced-to-lie-all-the-time-how-trans-and-non-binary-students-balance-professionalism-authenticity-and-safety-in-canadian-medical-programs
#17
JOURNAL ARTICLE
Kat Butler, Meredith Vanstone, Adryen Yak, Albina Veltman
INTRODUCTION: Promoting the inclusion of trans and non-binary (TNB) medical trainees is a key step in building an inclusive health workforce well-positioned to provide high-quality healthcare to all patients. Existing data on the experiences of TNB physicians and trainees describe widespread challenges related to prejudice and discrimination, with most trainees concealing their gender identity for fear of discrimination. We aimed to understand how TNB medical students have experienced professionalism and professional identity formation...
2024: Perspectives on Medical Education
https://read.qxmd.com/read/38397577/milk-and-its-derivatives-as-sources-of-components-and-microorganisms-with-health-promoting-properties-probiotics-and-bioactive-peptides
#18
REVIEW
Laura Quintieri, Francesca Fanelli, Linda Monaci, Vincenzina Fusco
Milk is a source of many valuable nutrients, including minerals, vitamins and proteins, with an important role in adult health. Milk and dairy products naturally containing or with added probiotics have healthy functional food properties. Indeed, probiotic microorganisms, which beneficially affect the host by improving the intestinal microbial balance, are recognized to affect the immune response and other important biological functions. In addition to macronutrients and micronutrients, biologically active peptides (BPAs) have been identified within the amino acid sequences of native milk proteins; hydrolytic reactions, such as those catalyzed by digestive enzymes, result in their release...
February 16, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38396627/mutations-in-the-foxo3-gene-and-their-effects-on-meat-traits-in-gannan-yaks
#19
JOURNAL ARTICLE
Youpeng Qi, Xiangyan Wang, Chune Zhu, Baohong Mi, Changze Cui, Shaopeng Chen, Zhidong Zhao, Fangfang Zhao, Xiu Liu, Jiqing Wang, Bingang Shi, Jiang Hu
The FOXO3 gene, a prominent member of the FOXO family, has been identified as a potential quantitative trait locus for muscle atrophy and lipid metabolism in livestock. It is also considered a promising candidate gene for meat quality traits such as Warner-Bratzler shear force (WBSF) and water holding capacity (WHC). The aim of this study was to identify sequence mutations in the FOXO3 gene of yaks and to analyze the association of genotypes and haplotypes with meat traits such as WBSF and WHC. Quantitative reverse-transcriptase PCR (RT-qPCR) was applied to determine the expression levels of FOXO3 in yak tissues, with the results revealing a high expression in the yak longissimus dorsi muscle...
February 6, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38395831/identification-of-circrna-associated-cerna-networks-in-the-longissimus-dorsi-of-yak-under-different-feeding-systems
#20
JOURNAL ARTICLE
Xiaoming Ma, Xian Guo, La Yongfu, Tong Wang, Pengjia Bao, Min Chu, Xiaoyun Wu, Ping Yan, Chunnian Liang
BACKGROUND: Yaks (Bos grunniens), prized for their ability to thrive in high-altitude environments, are indispensable livestock in the plateau region. Modifying their feeding systems holds significant promise for improving their growth and meat quality. Tenderness, a key determinant of yak meat quality and consumer appeal, is demonstrably influenced by dietary regimen. Indoor feeding regimes have been shown to enhance tenderness by lowering shear stress and optimizing pH values. CircRNAs, well-known modulators of circulatory function, also play a crucial role in skeletal muscle development across various animal species...
February 24, 2024: BMC Veterinary Research
keyword
keyword
171762
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.