keyword
https://read.qxmd.com/read/34408561/ocular-manifestations-of-skin-diseases-with-pathological-keratinization-abnormalities
#21
REVIEW
Alexander Zdebik, Natalia Zdebik, Matthias Fischer
Keratinization means cytodifferentiation of keratinocytes turning into corneocytes in the stratum corneum. Disorders of keratinization (hyperkeratosis, parakeratosis and dyskeratosis) are causing many dermatological diseases, including various types of ichthyoses, pachyonychia congenita, pityriasis rubra pilaris, all subtypes of psoriasis, pityriasis lichenoides, dyskeratosis congenita, leukoplakia and keratosis follicularis, which apart from skin lesions may affect the eye's adnexae causing ectropion, entropion, blepharitis, madarosis, and trichiasis, the ocular surface causing keratitis, conjunctivitis, corneal ulceration and episcleritis, which in turn cause uveitis and various fundoscopic changes (proliferative retinopathy, retinal vasculopathy, macular oedema and birdshot chorioretinopathy)...
February 2021: Postȩpy Dermatologii i Alergologii
https://read.qxmd.com/read/34124175/symptom-based-identification-of-g-4-chili-leaf-diseases-based-on-rotation-invariant
#22
JOURNAL ARTICLE
Sufola Das Chagas Silva Araujo, V S Malemath, K Meenakshi Sundaram
Instinctive detection of infections by carefully inspecting the signs on the plant leaves is an easier and economic way to diagnose different plant leaf diseases. This defines a way in which symptoms of diseased plants are detected utilizing the concept of feature learning (Sulistyo et al., 2020). The physical method of detecting and analyzing diseases takes a lot of time and has chances of making many errors (Sulistyo et al., 2020). So a method has been developed to identify the symptoms by just acquiring the chili plant leaf image...
2021: Frontiers in Robotics and AI
https://read.qxmd.com/read/33823264/efficiency-of-prophylactic-ablation-of-the-tributary-venous-pathways-draining-around-the-saphenofemoral-junction-to-decrease-the-rate-of-future-varicose-vein-and-symptoms-occurence
#23
JOURNAL ARTICLE
Mustafa Ozer Ulukan, Atalay Karakaya, Korhan Erkanli, Metin Onur Beyaz, Didem Melis Oztas, Murat Ugurlucan
BACKGROUND: There are various other collaterals draining into the venous system around the saphenofemoral junction in addition to the great saphenous vein. We aimed to determine the efficiency of prophylactic ablation of tributary veins in long term varicose vein and symptom recurrence. METHODS: Two hundred and sixty three consecutive patients whom underwent radiofrequency ablation therapy for the treatment of superficial venous reflux disease were investigated...
April 3, 2021: Annals of Vascular Surgery
https://read.qxmd.com/read/33799037/associations-between-baseline-cortisol-and-trajectory-of-symptom-improvement-in-depressed-adolescents-receiving-psychological-therapy
#24
JOURNAL ARTICLE
Ankit Chadha, Sharon Neufeld, Ian Michael Goodyer, Peter Fonagy, Nick Midgley, Paul Oliver Wilkinson
BACKGROUND: Cortisol hypersecretion in depressed adolescents and adults is associated with more persistent illness and may signal a lower response to psychological therapies. A meta-analysis of small and heterogenous studies demonstrated that higher pre-treatment basal cortisol levels were associated with poorer response specifically to psychological therapy for depression. The objective of this study was to investigate the relationship between both morning and evening salivary cortisol levels and response to psychological therapy in depressed adolescents participating in one large randomised controlled trial...
March 23, 2021: Journal of Affective Disorders
https://read.qxmd.com/read/33691368/-depression-symtoms-and-related-factors-of-fire-fighters
#25
JOURNAL ARTICLE
X C Zhang, X Y Yang, C Liu, J J Luo
Objective: To analysis the status of the mental health and related factors of fire fighters in Tianjin Binhai New District, and to provide suggestions for their psychological health protection. Methods: 399 fire fighters in Tianjin Binhai New District were selected as study subjects in Jan to April 2019. Depression symptoms were measured by the depression module of the Patient Health Questionnaire (PHQ-9) . The Chinese version of Efrort Reword Imbalance (ERI) Questionnnaire were used to investigate and evaluate their occupational stress...
February 20, 2021: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://read.qxmd.com/read/33474718/-recurrent-psychotic-symtoms-over-several-years-were-caused-by-huntington-s-disease
#26
JOURNAL ARTICLE
Per Breimer, Åsa Petersén, Håkan Widner
Huntington disease (HD) is a progressive neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. It is inherited in an autosomal dominant fashion with full penetrance. Around 15% of cases arise from spontaneous expansion of the CAG repeat. The clinical presentation includes involuntary movements (chorea) with dysarthria and dysphagia as well as cognitive and psychiatric symptoms and weight loss. The combination of these symptoms and signs should lead to further investigations regarding HD, even in absence of a known family history...
January 19, 2021: Läkartidningen
https://read.qxmd.com/read/33259817/clinical-and-biochemical-parameters-of-covid-19-patients-with-prior-or-active-dengue-fever
#27
JOURNAL ARTICLE
Isabella Márcia Soares Nogueira Teotônio, Juliana Lott de Carvalho, Luiz Cláudio Castro, Nadjar Nitz, Luciana Hagström, Geraldo Gonçalves Rios, Maria de Fátima Rodrigues de Oliveira, Bruno Stéfano Lima Dallago, Mariana Hecht
Originated in Wuhan, China, the coronavirus 19 disease (COVID-19) has quickly spread worldwide, reaching countries that already faced other endemics and epidemics. In Brazil, such a concerning situation includes arboviruses, among which the dengue virus stands out. Here, we determined the rate of SARS-CoV-2/dengue virus co-infection in a total of 178 patients with COVID-19 symtoms admitted into a large public hospital of the Federal District of Brazil. Furthermore, we evaluated whether prior or active dengue virus infection influenced hematological, biochemical, and clinical parameters of such patients...
February 2021: Acta Tropica
https://read.qxmd.com/read/32859497/severe-linezolid-induced-lactic-acidosis-in-a-child-with-acute-lymphoblastic-leukemia-a-case-report
#28
Vratislav Smolka, Marie Rohanova, Barbora Ludikova, Zbynek Novak, Martin Zapalka, Dagmar Pospisilova, Jana Volejnikova
Linezolid is an antibiotic increasingly used for treatment of resistant Gram-positive infections, which blocks bacterial proteosythesis through direct inhibition of mitochondrial ribosomes. The most common adverse effects of linezolid include gastrointestinal symtoms, peripheral neuropathy, bone marrow depression and lactic acidosis. Here we present a rare case of a 9-year-old female, a survivor of acute lymphoblastic leukemia (ALL) and a hematopoietic stem cell transplant (HSCT), who developed life-threatening lactic acidosis with vomiting, impaired consciousness and Kussmaul breathing after 51 days of intravenous linezolid administration due to mycobacterial infection...
August 25, 2020: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/32813936/sex-differences-in-the-association-between-ptsd-symptoms-with-cardiac-autonomic-function-and-subclinical-atherosclerotic-risk
#29
JOURNAL ARTICLE
Michael E Holmstrup, Brock T Jensen, Alaina C Glasgow, Kevin S Heffernan
BACKGROUND: Posttraumatic stress disorder (PTSD) is a public health concern that may elevate the risk for cardiovascular disease (CVD). There are established sex-differences in both PTSD risk and CVD risk. PURPOSE: To examine sex-specific associations between subclinical PTSD symptom severity and subclinical CVD risk in young men and women. METHODS: 61 young adults (women: n=29, mean age: 26±7 years) completed the post-traumatic stress disorder civilian checklist (PCL) and the Center for Epidemiologic Studies Depression scale (CES-D)...
August 19, 2020: Clinical Physiology and Functional Imaging
https://read.qxmd.com/read/32584440/white-matter-lesions-and-temporal-atrophy-are-associated-with-cognitive-and-neuropsychiatric-symptoms-in-patients-with-hypertension-and-alzheimer%C3%A2-s-disease
#30
JOURNAL ARTICLE
José María García-Alberca, Silvia Mendoza, Esther Gris, José Luis Royo, José Manuel Cruz-Gamero, Natalia García-Casares
OBJECTIVES: An increasing evidence suggests hypertension (HTN) could be linked to cognitive impairment and incident Alzheimer disease (AD). The precise mechanisms linking HTN and AD are not well known. The aim of this study was to assess the putative association between HTN and AD. METHODS: We assessed in patients with AD associations between HTN and demographic and clinical data, vascular risk factors, treatments, APOE genotypes, brain white matter hyperintensities (WMH), and medial temporal atrophy (MTA) in multivariate analysis of covariance...
June 25, 2020: International Journal of Geriatric Psychiatry
https://read.qxmd.com/read/32513546/an-attachment-perspective-on-the-risk-for-psychosis-clinical-correlates-and-the-predictive-value-of-attachment-patterns-and-mentalization
#31
JOURNAL ARTICLE
Tommaso Boldrini, Maria Pontillo, Annalisa Tanzilli, Guido Giovanardi, Giuseppe Di Cicilia, Silvia Salcuni, Stefano Vicari, Vittorio Lingiardi
BACKGROUND: In a longitudinal design, the present study examined: (a) the nature of attachment patterns and reflective functioning (RF) in individuals at ultra-high risk for psychosis (UHR); (b) the association between RF and subclinical psychotic symtoms; and (c) the psychosis-predictive value of attachment patterns, RF, and the interaction between these factors. METHOD: The sample comprised 57 UHR subjects and 53 clinical controls (non-UHR). UHR subjects were followed over a mean period of 14 months (SD = 2...
June 5, 2020: Schizophrenia Research
https://read.qxmd.com/read/32463475/-rapid-point-of-care-serology-testing-for-sars-cov-2
#32
JOURNAL ARTICLE
Otto Stackelberg, Mouna Esmaeilzadeh, Björn Olsen, Åke Lundkvist
Increasing evidence indicates immunity against severe acute respiratory syndrome coronavirus 2 (sars-cov-2) after covid-19, but it remains unclear for how long the protection remains. Serology testing seems to have a higher sensitivity than molecular diagnostics from 8 days after onset of symtoms, and should be part of risk assessment and epidemiological studies of COVID-19. The performance of commercial serological point-of-care (POC) lateral flow tests are highly manufacturer-dependant. Low sensitivity increases the risk of false negative results and could result in unnecessary quarantine of test persons with developed antibodies...
May 27, 2020: Läkartidningen
https://read.qxmd.com/read/32410653/a-rare-case-of-pediatric-recurrent-rhabdomyolysis-with-compound-heterogenous-variants-in-the-lpin1
#33
JOURNAL ARTICLE
Ruochen Che, Chunli Wang, Bixia Zheng, Xuejuan Zhang, Guixia Ding, Fei Zhao, Zhanjun Jia, Aihua Zhang, Songming Huang, Quancheng Feng
BACKGROUND: Lipin-1, encoded by LPIN1 gene, serves as an enzyme and a transcriptional co-regulator to regulate lipid metabolism and mitochondrial respiratory chain. Autosomal recessive mutations in LPIN1 were recognized as one of the most common causes of pediatric recurrent rhabdomyolysis in western countries. However, to date, there were only a few cases reported in Asian group. This study aims to report the first pediatric case of recurrent rhabdomyolysis with a novel LPIN1 mutation in China mainland in order to raise the awareness of both pediatricians and patients...
May 14, 2020: BMC Pediatrics
https://read.qxmd.com/read/32344167/umifenovir-treatment-is-not-associated-with-improved-outcomes-in-patients-with-coronavirus-disease-2019-a-retrospective-study
#34
JOURNAL ARTICLE
N Lian, H Xie, S Lin, J Huang, J Zhao, Q Lin
OBJECTIVES: Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Umifenovir (Arbidol®) is an antiviral drug being used to treat influenza in Russia and China. This study aimed to investigate the effectiveness and safety of umifenovir for COVID-19. METHODS: A retrospective study was performed in a non-intensive care unit (ICU) ward in Jinyintan Hospital from 2 February 2020 to 20 March 2020. COVID-19 was confirmed by real-time reverse-transcriptase polymerase chain reaction (RT-PCR) assay of pharyngeal swab specimens...
July 2020: Clinical Microbiology and Infection
https://read.qxmd.com/read/32324968/does-high-cardiorespiratory-fitness-confer-some-protection-against-pro-inflammatory-responses-after-infection-by-sars-cov-2
#35
REVIEW
Hermann Zbinden-Foncea, Marc Francaux, Louise Deldicque, John A Hawley
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated in China in late 2019 and has since spread rapidly to every continent in the world. This pandemic continues to cause widespread personal suffering, along with severe pressure on medical and health care providers. The symtoms of SARS-CoV-2 and the subsequent prognosis is worsened in individuals who have pre-exisiting comorbidities prior to infection by the virus. Individuals with obesity/overweight, insulin resistance and diabetes typically have chronic low-grade inflammation characterized by increased levels of several pro-inflammatory cytokines and the inflammasome: this state predisposes to greater risk for infection along with more adverse outcomes...
April 23, 2020: Obesity
https://read.qxmd.com/read/32106087/the-influence-of-restless-legs-symptoms-on-musculoskeletal-pain-in-depression
#36
JOURNAL ARTICLE
Piritta Auvinen, Hannu Koponen, Hannu Kautiainen, Katariina Korniloff, Tiina Ahonen, Mauno Vanhala, Pekka Mäntyselkä
Background and aims Restless legs syndrome is a sensorimotor disorder associated with mental health conditions notably depression. Restless legs symptoms and depression are commonly associated with pain. The study investigated the influence of restless legs symptoms on musculoskeletal pain in patients with depression or with increased depressive symptoms. Methods A cross-sectional study of primary care patients in the Central Finland Hospital District. The prevalence of restless legs symptoms was studied in patients with depressive symptoms (n = 695) and controls without a psychiatric diagnosis (n = 410) by using a structured questionnaire...
February 27, 2020: Scandinavian Journal of Pain
https://read.qxmd.com/read/31729207/posterior-reversible-encephalopathy-syndrome-in-children-with-acute-lymphoblastic-leukemia-during-remission-induction-chemotherapy-a-single-center-retrospective-study
#37
JOURNAL ARTICLE
Wei Lin, Jing Xie, Jishui Zhang, Hua Cheng, Haijing Cui, Yuanyuan Zhang, Ying Wu, Jiaole Yu, Peijing Qi, Jia Fan, Huifang Gao, Fang Wang, Ruidong Zhang, Huyong Zheng
BACKGROUND: This study investigated the clinical characteristics, cranial magnetic resonance imaging (MRI) features, MRI follow-up, and prognosis of children with acute lymphoblastic leukemia (ALL) who developed posterior reversible encephalopathy syndrome (PRES) during remission induction chemotherapy. METHODS: We analyzed the age, gender, PRES symptoms and signs, cranial MRI findings, therapeutic effect, and prognosis of children with ALL who developed PRES during chemotherapy from January 2010 to December 2013 at the Hematology Oncology Center of Beijing Children's Hospital...
November 11, 2019: Minerva Pediatrica
https://read.qxmd.com/read/31591874/overview-of-echinococcus-multilocularis-in-turkey-and-in-the-world
#38
JOURNAL ARTICLE
Ali Tümay Gürler, Cenk Soner Bölükbaş, Mustafa Açıcı, Şinasi Umur
Echinococcus multilocularis , a heteroxen and zoonotic parasite, is found in the intestine of carnivores, particularly foxes. Adult cestodes are regarded apathogenic in definitive hosts, while metacestode, the alveolar form, is high pathogenic for intermediate hosts. The alveolar cyst causes a maling tumor-like lesions with infiltrative, proliferative and destructive character which locates in the liver primarily, then metastasizes to other organs. If it is not treated in intermediate hosts it causes irreversible symtoms and death after located in vital organs such as liver, lungs, brain...
October 7, 2019: Türkiye Parazitolojii Dergisi
https://read.qxmd.com/read/31432989/epidemiological-profile-of-zika-dengue-and-chikungunya-virus-infections-identified-by-medical-and-molecular-evaluations-in-rondonia-brazil
#39
JOURNAL ARTICLE
Deusilene Souza Vieira, Miriam Ribas Zambenedetti, Luciana Requião, Ivo Alberto Borghetti, Luciano Kleber de Souza Luna, Alcione de Oliveira Dos Santos, Roger Lafontaine Mesquita Taborda, Dhelio Batista Pereira, Marco Aurélio Krieger, Juan Miguel Villalobos Salcedo, Rita de Cássia Pontello Rampazzo
Several arboviruses have emerged and/or re-emerged in North, Central and South-American countries. Viruses from some regions of Africa and Asia, such as the Zika and Chikungunya virus have been introduced in new continents causing major public health problems. The aim of this study was to investigate the presence of RNA from Zika, Dengue and Chikungunya viruses in symptomatic patients from Rondonia, where the epidemiological profile is still little known, by one-step real-time RT-PCR. The main clinical signs and symtoms were fever (51...
August 19, 2019: Revista do Instituto de Medicina Tropical de São Paulo
https://read.qxmd.com/read/31319121/%C3%AE-glucosidase-inhibitory-activity-and-in-vivo-antihyperglycemic-effect-of-secondary-metabolites-from-the-leaf-infusion-of-ocimum-campechianum-mill
#40
JOURNAL ARTICLE
Javier A Ruiz-Vargas, Dulce L Morales-Ferra, Guillermo Ramírez-Ávila, Alejandro Zamilpa, Elizabeth Negrete-León, Juan José Acevedo-Fernández, Luis M Peña-Rodríguez
ETHNOPHARMACOLOGICAL RELEVANCE: Wild basil (Ocimum campechianum Mill.), an aromatic herb of the Lamiaceae family known as "albahaca de monte" (Spanish) or "x'kakaltun" (Mayan) in Yucatan, is used in Mayan traditional medicine to treat diabetes, as well as to alleviate fever symtoms, stomach pain, conjunctivitis, and various skin affections. AIM OF THE STUDY: To isolate and identify the bioactive metabolites responsible for the α-glucosidase inhibitory activity previously detected in the leaf infusion O...
July 15, 2019: Journal of Ethnopharmacology
keyword
keyword
171753
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.