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https://www.readbyqxmd.com/read/29151279/detection-of-ctcs-in-cervical-cancer-using-a-conditionally-replicative-adenovirus-targeting-telomerase-positive-cells
#1
Masahiro Takakura, Takeo Matsumoto, Mitsuhiro Nakamura, Yasunari Mizumoto, Subaru Myojyo, Rena Yamazaki, Jyunpei Iwadare, Yukiko Bono, Shunsuke Orisaka, Takeshi Obata, Takashi Izuka, Kyosuke Kagami, Kentaro Nakayama, Hideki Hayakawa, Fuminori Sakurai, Hiroyuki Mizuguchi, Yasuo Urata, Toshiyoshi Fujiwara, Satoru Kyo, Toshiyuki Sasagawa, Hiroshi Fujiwara
Circulating tumor cells (CTCs) are newly discovered biomarkers of cancers. Although many systems detect CTCs, a gold standard has not yet been established. We analyzed CTCs in uterine cervical cancer patients using an advanced version of conditionally replicative adenovirus targeting telomerase-positive cells, which was enabled to infect coxsackievirus-adenovirus receptor-negative cells and to reduce false-positive signals in myeloid cells. Blood samples from cervical cancer patients were hemolyzed and infected with the virus and then labeled with fluorescent anti-CD45 and anti-pan cytokeratin antibodies...
November 19, 2017: Cancer Science
https://www.readbyqxmd.com/read/29151266/crystal-structure-and-catalytic-characterization-of-the-dehydrogenase-reductase-sdr-family-member-4-dhrs4-from-caenorhabditis-elegans
#2
Michael Kisiela, Annette Faust, Bettina Ebert, Edmund Maser, Axel J Scheidig
The human dehydrogenase/reductase SDR family member 4 (DHRS4) is a tetrameric protein that is involved in the metabolism of several aromatic carbonyl compounds, steroids and bile acids. The only invertebrate DHRS4 that has been characterized to date is that from the model organism Caenorhabditis elegans. We have previously cloned and initially characterized this protein that was recently annotated as DHRS4_CAEEL in the UniProtKB database. Crystallization and X-ray diffraction studies of the full-length DHRS4_CAEEL protein in complex with diacetyl revealed its tetrameric structure and showed that two subunits are connected via an intermolecular disulfide bridge that is formed by N-terminal cysteine residues (Cys5) of each protein chain, which increases the enzymatic activity...
November 19, 2017: FEBS Journal
https://www.readbyqxmd.com/read/29151223/correction-to-pain-psychological-comorbidities-disability-and-impaired-quality-of-life-in-hidradenitis-suppurativa
#3
Zarine S Patel, Lauren K Hoffman, Dawn C Buse, Amy S Grinberg, Ladan Afifi, Steven R Cohen, Michelle A Lowes, Elizabeth K Seng
The original version of this article contains an error in the spelling of the title. The title should read: Pain, Psychological Comorbidities, Disability, and Impaired Quality of Life in Hidradenitis Suppurativa.
November 18, 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29151183/correction-to-a-bibliometric-analysis-of-research-on-haze-during-2000-2016
#4
Chenxi Li, Kening Wu, Jingyao Wu
The original version of this article unfortunately contains mistakes.
November 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29151047/interpretation-of-health-news-items-reported-with-or-without-spin-protocol-for-a-prospective-meta-analysis-of-16-randomised-controlled-trials
#5
Romana Haneef, Amélie Yavchitz, Philippe Ravaud, Gabriel Baron, Ivan Oranksy, Gary Schwitzer, Isabelle Boutron
INTRODUCTION: We aim to compare the interpretation of health news items reported with or without spin. 'Spin' is defined as a misrepresentation of study results, regardless of motive (intentionally or unintentionally) that overemphasises the beneficial effects of the intervention and overstates safety compared with that shown by the results. METHODS AND ANALYSIS: We have planned a series of 16 randomised controlled trials (RCTs) to perform a prospective meta-analysis...
November 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/29150969/non-operative-treatment-as-a-strategy-for-patients-with-parastomal-hernia-a-multicentre-retrospective-cohort-study
#6
L F Kroese, D P V Lambrichts, J Jeekel, G J Kleinrensink, A G Menon, E J R de Graaf, W A Bemelman, J F Lange
AIM: Parastomal hernia is the most common complication following stoma construction. Surgical treatment is usually chosen over non-operative treatment, but a clear rationale for the choice of management is often lacking. This study aims to investigate the reasons for non-operative treatment, cross-over rates, and postoperative complications. METHOD: A multicentre, retrospective cohort study was conducted. Patients diagnosed with a parastomal hernia between January 2007 and December 2012 were included...
November 18, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29150901/expression-of-the-clock-gene-rev-erb%C3%AE-in-the-brain-controls-the-circadian-organization-of-food-intake-and-locomotor-activity-but-not-daily-variations-of-energy-metabolism
#7
Satish Sen, Stéphanie Dumont, Dominique Sage-Ciocca, Sophie Reibel, Paul de Goede, Andries Kalsbeek, Etienne Challet
The nuclear receptor REV-ERBα is part of the molecular clock mechanism and thought to be involved in a variety of biological processes within metabolically active peripheral tissues as well. To investigate whether Rev-erbα (also known as Nr1d1) in the brain plays a role in the daily variations of energy metabolism, feeding behaviour and the sleep-wake cycle, we studied mice with global (GKO) or brain (BKO) deletion of Rev-erbα. Mice were studied both in a light-dark cycle and constant darkness, and 24-h variations of Respiratory quotient (RQ) and energy expenditure, as well as the temporal patterns of rest-activity and feeding behavior were recorded...
November 18, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29150898/a-model-to-characterize-psychopathological-features-in-adults-with-prader-willi-syndrome
#8
Denise Thuilleaux, Virginie Laurier, Pierre Copet, Julie Tricot, Geneviève Demeer, Fabien Mourre, Maithé Tauber, Joseba Jauregi
High prevalence of behavioral and psychiatric disorders in adults with Prader-Willi Syndrome (PWS) has been reported in last few years. However, data are confusing and often contradictory. In this article, we propose a model to achieve a better understanding of the psychopathological features in adults with PWS. The study is based on clinical observations of 150 adult inpatients, males and females. Non-parametric statistics were performed to analyse the association of psychopathological profiles with genotype, gender and age...
November 17, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29150825/correction-to-phylogenetic-insight-into-zika-and-emerging-viruses-for-a-perspective-on-potential-hosts
#9
Diana S Weber, Karen A Alroy, Samuel M Scheiner
The article Phylogenetic Insight into Zika and Emerging Viruses for a Perspective on Potential Hosts, written by Diana S. Weber, Karen A. Alroy, and Samuel M. Scheiner, was originally published Online First without open access.
November 17, 2017: EcoHealth
https://www.readbyqxmd.com/read/29150271/xenohormesis-in-early-life-new-avenues-of-research-to-explore-anti-aging-strategies-through-the-maternal-diet
#10
Philippe de Medina
Aging is a progressive internal physiological deterioration of the organism, leading to the occurrence of age-related lethal diseases. It has become a major societal challenge to understand the processes that drive aging and to develop rational pharmacological agents and dietary approaches to fight against age-related deterioration and diseases. Interestingly, several lines of evidence highlight an influence of the developmental period on the risk of age-related diseases later in life. This field is known as the developmental origins of health and disease...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29150230/cesarean-birth-what-s-in-a-name
#11
L Ni, A Elsaharty, I McConachie
BACKGROUND: Cesarean birth is known as both cesarean section (CS) or cesarean delivery (CD). The International Journal of Obstetric Anesthesia (IJOA) is the leading obstetric anesthesia journal, and a barometer of attitudes within the profession. The journal recently published the hundredth issue, spanning 25 years (to December 2016). It is an opportune time to examine the evolution of surgical birth terminology (CS versus CD) during that period. METHODS: We examined 1583 articles in IJOA, subdividing them into editorials, papers, review articles, debates and case reports...
September 28, 2017: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/29150032/thoracic-surgery-in-patients-with-aids
#12
REVIEW
Doraid Jarrar, Grace Y Song
The picture of human immunodeficiency virus (HIV)-infected patients has changed dramatically since the original description in 1981. The introduction of antiretroviral drugs in 1987 and combination antiretroviral therapy has decreased mortality by as much as 80%. We now see patients in their 60s and 70s, having lived decades with HIV and living a normal live. As outlined in the article, despite good viral control, patients with HIV may present with solid organ cancers earlier than noninfected patients and are also prone to other complications of their disease that may require the attention of a thoracic surgeon...
February 2018: Thoracic Surgery Clinics
https://www.readbyqxmd.com/read/29149888/correction-to-analysis-of-plasma-multiplex-cytokines-and-increased-level-of-il-10-and-il-1ra-cytokines-in-febrile-seizures
#13
Kyungmin Kim, Byung Ok Kwak, Aram Kwon, Jongseok Ha, Soo-Jin Kim, Sun Whan Bae, Jae Sung Son, Soo-Nyung Kim, Ran Lee
After publication of the article [1], it has been brought to our attention that several of the authors' names were formatted incorrectly in the original version of the article. The corrections are listed below -"Byungok Kwak" should be "Byung Ok Kwak"Soojin Kim" should be "Soo-Jin Kim"Sunwhan Bae" should be "Sun Whan Bae"Jaesung Son" should be "Jae Sung Son"Soonyung Kim" should be "Soo-Nyung Kim"The original version of the article has now been revised.
November 17, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29149582/corrigendum-the-science-and-practice-of-self-control
#14
(no author information available yet)
Original article: Duckworth, A. L., & Seligman, M. E. P. (2017). The science and practice of self-control. Perspectives on Psychological Science, 12, 715-718. doi:10.1177/1745691617690880 On p. 715, right column, first paragraph, Duckworth, Tsukayama, and May (2010) should have been cited instead of Emanuele et al. (2010). The reference list should not have included Emanuele et al. (2010). Instead, the following reference should have been included: Duckworth, A. L., Tsukayama, E., & May, H. (2010). Establishing causality using longitudinal hierarchical linear modeling: An illustration predicting achievement from self-control...
November 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/29149425/correction-to-efficacy-and-safety-of-full-length-pegylated-recombinant-factor-viii-with-extended-half-life-in-previously-treated-patients-with-hemophilia-a-comparison-of-data-between-the-general-and-japanese-study-populations
#15
Keiji Nogami, Midori Shima, Katsuyuki Fukutake, Teruhisa Fujii, Masashi Taki, Tadashi Matsushita, Satoshi Higasa, Tetsuji Sato, Michio Sakai, Morio Arai, Haruhiko Uchikawa, Werner Engl, Brigitt Abbuehl, Barbara A Konkle
The authors would like to correct the error in Table 2 in the original publication of the article. The "Blood type" is not described in any part of "Results" and "Discussion" and had no impact on the conclusion hence the bottom of the table is removed.
November 17, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/29148842/erratum
#16
(no author information available yet)
Yao H, Lu H, Zhao H, et al. Open reduction assisted with an external fixator and internal fixation with calcaneal locking plate for intra-articular calcaneal fractures. Foot Ankle Int. 2017;38(10):1107-1114. (Original DOI: 10.1177/1071100717715908) The above article appeared with the incorrect corresponding author. The correct corresponding author is Huading Lu, PhD. The corrected corresponding author information is below: Corresponding Author: Huading Lu, PhD, Department of Orthopaedics, The Fifth Affiliated Hospital of Sun Yat-sen University, NO...
November 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/29148237/supraclavicular-flap-repair-in-the-free-flap-era
#17
REVIEW
Jodie Trautman, Sinclair Gore, Matthew Potter, Jonathan Clark, Dylan Hyam, Ngian C Tan, Quan Ngo, Bruce Ashford
BACKGROUND: Supraclavicular flap (SCF) repair is widely reported in head and neck surgery in select patients and defects. The authors' objective is to present our series of 30 patients who underwent SCF repair for varying defects and to review the scope and outcome of SCF repair in the literature. METHODS: The authors contributed primary evidence of 30 cases of SCF repair. Our outcomes are compared with those reported in the last 5 years' literature; 33 articles published between January 2012 and January 2017 that present original clinical experience of 528 SCFs...
November 17, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29148109/notch-signaling-controls-transdifferentiation-of-pulmonary-neuroendocrine-cells-in-response-to-lung-injury
#18
Erica Yao, Chuwen Lin, Qingzhe Wu, Kuan Zhang, Hai Song, Pao-Tien Chuang
Production of an appropriate number of distinct cell types in precise locations during embryonic development is critical for proper tissue function. Homeostatic renewal or repair of damaged tissues in adults also requires cell expansion and transdifferentiation to replenish lost cells. However, the responses of diverse cell types to tissue injury are not fully elucidated. Moreover, the molecular mechanisms underlying transdifferentiation remain poorly understood. This knowledge is essential for harnessing the regenerative potential of individual cell types...
November 16, 2017: Stem Cells
https://www.readbyqxmd.com/read/29147898/-don-t-mind-the-gap-reflections-on-improvement-science-as-a-paradigm
#19
Trenholme Junghans
Responding to this issue's invitation to bring new disciplinary insights to the field of improvement science, this article takes as its starting point one of the field's guiding metaphors: the imperative to "mind the gap". Drawing on insights from anthropology, history, and philosophy, the article reflects on the origins and implications of this metaphoric imperative, and suggests some ways in which it might be in tension with the means and ends of improvement. If the industrial origins of improvement science in the twentieth century inform a metaphor of gaps, chasms, and spaces of misalignment as invariably imperfect and potentially dangerous, and therefore requiring bridging or closure, other currents that feed the discipline of improvement science suggest the potential value and uses of spaces of openness and ambiguity...
November 17, 2017: Health Care Analysis: HCA: Journal of Health Philosophy and Policy
https://www.readbyqxmd.com/read/29147801/correction-to-peripheral-markers-of-autophagy-in-polyglutamine-diseases
#20
Giorgia Puorro, Angela Marsili, Francesca Sapone, Chiara Pane, Anna De Rosa, Silvio Peluso, Giuseppe De Michele, Alessandro Filla, Francesco Saccà
Dr. Peluso's given name and family name were initially interchanged inadvertently. The correct names have been corrected above. The original article was corrected.
November 17, 2017: Neurological Sciences
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