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Liming Liang

Linan Liu, Lihua Wang, Wenhong Song, Liang Yang, Liming Yin, Shaopan Xia, Hailong Wang, Peter James Strong, Zhaoliang Song
Fruit shell residue from Xanthoceras sorbifolia was investigated as a potential biosorbent to remove crude oil from aqueous solution. The shell powder and its carbonized material were compared while assessing various factors that influenced oil removal capacity. The structure and sorption mechanism were characterized using scanning electron microscopy and Fourier-transform infrared spectroscopy. The oil removal capacity of the raw material (75.1 mg g-1 ) was better than the carbonized material (49.5 mg g-1 )...
August 18, 2018: Environmental Science and Pollution Research International
Qingwen Zhu, Yufei Ni, Jing Wang, Honggang Yin, Qin Zhang, Lingli Zhang, Wenjun Bian, Bo Liang, Lingyin Kong, Liming Xuan, Naru Lu
Cerebral palsy (CP) is a non-progressive neurological disease, of which susceptibility is linked to genetic and environmental risk factors. More and more studies have shown that CP might be caused by multiple genetic factors, similar to other neurodevelopmental disorders. Due to the high genetic heterogeneity of CP, we focused on investigating related molecular pathways. Ten children with CP were collected for whole-exome sequencing by next-generation sequencing (NGS) technology. Customized processes were used to identify potential pathogenic pathways and variants...
August 14, 2018: Genes & Genomics
Yan Zhou, Hanyang Liu, Jun Song, Liang Cao, Liming Tang, Chunjian Qi
Sinomenine (SIN), a pure alkaloid isolated from Sinomenium acutum, has been widely used in arthritis for its anti‑inflammatory effect, but little is known about the effect of SIN on human ulcerative colitis (UC). In the present study, the effect and mechanism of SIN was examined in a dextran sulfate sodium (DSS)‑induced murine colitis model, which mimics human UC. Oral administration of SIN significantly suppressed the elevated disease activity index and ameliorated colonic histological damage in a DSS‑induced colitis model...
August 10, 2018: Molecular Medicine Reports
Mohammad L Rahman, Liming Liang, Linda Valeri, Li Su, Zhaozhong Zhu, Shangzhi Gao, Golam Mostofa, Qazi Qamruzzaman, Russ Hauser, Andrea Baccarelli, David C Christiani
Altered expression of microRNAs (miRNAs) is implicated in fetal growth. However, the mechanisms by which placenta-derived miRNAs regulate birthweight are not well understood. In Phase 1, we compared the expression of 754 miRNAs in the placenta of mothers from two extreme birthweight groups (0.8-2.2 kg vs. 3.3-3.9 kg, n = 77 each) selected from an arsenic-exposed Bangladeshi birth cohort (n = 1,141). We identified 49 miRNAs associated with the extreme birthweight groups and/or gestational age in Phase 1, which were further analyzed in Phase 2 among 364 randomly selected mother-infant pairs...
August 13, 2018: Epigenetics: Official Journal of the DNA Methylation Society
Yuting Duan, Liming Lu, Juexuan Chen, Chunxiao Wu, Jielin Liang, Yan Zheng, Jinjian Wu, Peijing Rong, Chunzhi Tang
BACKGROUND: Alzheimer disease (AD) is the most common type of dementia with cognitive decline as one of the core symptoms in older adults. Numerous studies have suggested the value of psychosocial interventions to improve cognition in this population, but which one should be preferred are still matters of controversy. Consequently, we aim to compare and rank different psychosocial interventions in the management of mild to moderate AD with cognitive symptoms. METHODS: We did a network meta-analysis to identify both direct and indirect evidence in relevant studies...
August 7, 2018: BMC Geriatrics
Sen Liang, Rongguo Zhang, Dayang Liang, Tianci Song, Tao Ai, Chen Xia, Liming Xia, Yan Wang
Non-invasive prediction of isocitrate dehydrogenase ( IDH ) genotype plays an important role in tumor glioma diagnosis and prognosis. Recently, research has shown that radiology images can be a potential tool for genotype prediction, and fusion of multi-modality data by deep learning methods can further provide complementary information to enhance prediction accuracy. However, it still does not have an effective deep learning architecture to predict IDH genotype with three-dimensional (3D) multimodal medical images...
July 30, 2018: Genes
Liang Chen, Zhengu Chen, Yafei Kuang, Chenxi Xu, Liming Yang, Minjie Zhou, Binhong He, Mingjun Jing, Zhi Li, Fangyi Li, Zhongxue Chen, Zhaohui Hou
Biomass with abundant resources and low price is regarded as potential sources of functionalized carbon-based energy storage and conversion electrode materials. Rational construction and development of biomass-derived carbon equipped with proper morphology, structure, and composition prove the key to highly efficient utilization of advanced energy storage systems. Herein, we use palm tree bark hair as a biomass source and prepare edge/defect-rich quasi-mesoporous carbon (QMC) by a direct pyrolysis followed by NaOH etching strategy...
August 15, 2018: ACS Applied Materials & Interfaces
Xin You, Hongqiang Qin, Jiawei Mao, Yu Tian, Mingming Dong, Zhimou Guo, Xinmiao Liang, Liming Wang, Yan Jin, Mingliang Ye
Compared with N-linked glycosylation, the analysis of O-GalNAc glycosylation is extremely challenging due to the high structure diversity of glycans and lack of glycosidases to release O-GalNAc glycans. In this work, we presented a glycoform simplification strategy by combining HILIC enrichment with chemical de-sialylation to characterize O-GalNAc glycosylation of human serum. This method was first validated by using the bovine fetuin as the test sample. It was found that more than 90% of the sialic acid residues could be removed from bovine fetuin by the acid-assisted de-sialylation method, which significantly simplified the glycan structure and improved identification sensitivity...
July 22, 2018: Proteomics
Liming Cai, Zhenxiang Xi, André M Amorim, M Sugumaran, Joshua S Rest, Liang Liu, Charles C Davis
Whole-genome duplications (WGDs) are widespread and prevalent in vascular plants and frequently coincide with major episodes of global and climatic upheaval, including the mass extinction at the Cretaceous-Tertiary boundary (c. 65 Ma) and during more recent periods of global aridification in the Miocene (c. 10-5 Ma). Here, we explore WGDs in the diverse flowering plant clade Malpighiales. Using transcriptomes and complete genomes from 42 species, we applied a multipronged phylogenomic pipeline to identify, locate, and determine the age of WGDs in Malpighiales using three means of inference: distributions of synonymous substitutions per synonymous site (Ks ) among paralogs, phylogenomic (gene tree) reconciliation, and a likelihood-based gene-count method...
July 21, 2018: New Phytologist
Mohammad Mohebbi, Liang Ding, Russell L Malmberg, Cory Momany, Khaled Rasheed, Liming Cai
miRNAs are involved in many critical cellular activities through binding to their mRNA targets, e.g. in cell proliferation, differentiation, death, growth control, and developmental timing. Accurate prediction of miRNA targets can assist efficient experimental investigations on the functional roles of miRNAs. Their prediction, however, remains a challengeable task due to the lack of experimental data about the tertiary structure of miRNA-target binding duplexes. In particular, correlations of nucleotides in the binding duplexes may not be limited to the canonical Watson Crick base pairs (BPs) as they have been perceived; methods based on secondary structure prediction (typically minimum free energy (MFE)) have only had mix success...
May 7, 2018: Journal of Bioinformatics and Computational Biology
Liang Huang, Diana Santiago, Patricia Loyselle, Liming Dai
Along with the quick development of flexible and wearable electronic devices, there is an ever-growing demand for light-weight, flexible, and wearable power sources. Because of the high power density, excellent cycling stability and easy fabrication, flexible supercapacitors are widely studied for this purpose. Graphene-based nanomaterials are attractive electrode materials for flexible and wearable supercapacitors owing to their high surface area, good mechanical and electrical properties, and excellent electrochemical stability...
July 15, 2018: Small
Tian Liu, Jinming Luo, Xiaoyang Meng, Liming Yang, Bin Liang, Meijun Liu, Chengbin Liu, Aijie Wang, Xia Liu, Yong Pei, Jili Yuan, John Crittenden
Although noble metal electrocatalysts are highly efficient in the dehalogenation of halogenated antibiotics, the prohibitive cost hinders their practical applications. In this study, a cobalt-phosphorous/oxide (CoP/O) composite prepared via a one-step electrodeposition was for the first time applied in electroreductive dechlorination of halogenated antibiotics (HA), including chloramphenicol (CAP), florfenicol (FLO) and thiamphenicol (TAP). CoP/O had a higher FLO dechlorination efficiency (91%) than Pd/C (69...
September 15, 2018: Journal of Hazardous Materials
Christopher Papandreou, Mònica Bulló, Yan Zheng, Miguel Ruiz-Canela, Edward Yu, Marta Guasch-Ferré, Estefanía Toledo, Clary Clish, Dolores Corella, Ramon Estruch, Emilio Ros, Montserrat Fitó, Fernando Arós, Miquel Fiol, José Lapetra, Lluís Serra-Majem, Enrique Gómez-Gracia, Liming Liang, Georgios A Fragkiadakis, Cristina Razquin, Frank B Hu, Jordi Salas-Salvadó
Background: The role of trimethylamine-N-oxide (TMAO) in type 2 diabetes (T2D) is currently partially understood and controversial. Objective: The aim of this study was to investigate associations between TMAO and related metabolites with T2D risk in subjects at high risk of cardiovascular disease. Design: This is a case-cohort design study within the Prevención con Dieta Mediterránea (PREDIMED) study, with 251 incident T2D cases and a random sample of 694 participants (641 noncases and 53 overlapping cases) without T2D at baseline (median follow-up: 3...
July 1, 2018: American Journal of Clinical Nutrition
Zheng Li, Xue Xu, Liming Deng, Ruoxian Liao, Ruiying Liang, Bo Zhang, Luyong Zhang
The cardiovascular complications were highly prevalent in type 2 diabetes mellitus (T2DM), even at the early stage of T2DM or the state of intensive glycemic control. Therefore, there is an urgent need for the intervention of cardiovascular complications in T2DM. Herein, the new hybrids of NO donor and SGLT2 inhibitor were design to achieve dual effects of anti-hyperglycemic and anti-thrombosis. As expected, the preferred hybrid 2 exhibited moderate SGLT2 inhibitory effects and anti-platelet aggregation activities, and its anti-platelet effect mediated by NO was also confirmed in the presence of NO scavenger...
June 14, 2018: Bioorganic & Medicinal Chemistry
Ona Anilionyte, Hong Liang, Xiaoqiang Ma, Liming Yang, Kang Zhou
Expression of recombinant proteins in Escherichia coli often requires use of inducible promoters to shorten the lag phase and improve protein productivity and final protein titer. Synthetic molecules that cannot be metabolized by E. coli, such as isopropyl thiogalactopyranoside (IPTG), have been frequently used to trigger the protein expression during early exponential growth phase. This practice has many drawbacks, including high cost and toxicity of IPTG, complex operating procedure, and non-uniform protein expression pattern (some cells in the population do not express recombinant proteins)...
August 2018: Applied Microbiology and Biotechnology
Deirdre K Tobias, Clary Clish, Samia Mora, Jun Li, Liming Liang, Frank B Hu, JoAnn E Manson, Cuilin Zhang
BACKGROUND: Circulating branched-chain amino acids (BCAAs; isoleucine, leucine, valine) are consistently associated with increased type 2 diabetes (T2D) risk, but the relationship with dietary intake of BCAAs is less clear. METHODS: The longitudinal Nurses' Health Study II cohort conducted a blood collection from 1996 to 1999. We profiled plasma metabolites among 172 incident T2D cases and 175 age-matched controls from women reporting a history of gestational diabetes before blood draw...
August 2018: Clinical Chemistry
Ying Chu, Liming Qin, Liang Zhen, Qinmin Pan
Smart miniaturized aquatic devices have many important applications, but their locomotion at different interfaces remains a challenge. Here, we report a smart miniaturized submarine moving at various air/liquid or oil/water interfaces. The microsubmarine is fabricated by a CO2 -responsive superhydrophobic copper mesh and is driven by the Marangoni effect. The microsubmarine can not only transfer among different interfaces reversibly but also move horizontally at the interfaces freely. The unique locomotion of the device is attributed to a CO2 -triggered switch between superhydrophobicity and underwater superoleophobicity...
July 25, 2018: ACS Applied Materials & Interfaces
Xinpei Li, Ying Sun, Liming Yuan, Li Liang, Yanxiao Jiang, Huilan Piao, Daqian Song, Aimin Yu, Xinghua Wang
This work describes a nanohybrid material consisting of gold nanoparticles (AuNPs) and nanosheets of layered double hydroxides (NLDHs) of Mg(II) and Al(III). Mono-disperse AuNPs were immobilized on the surface of the LDHs via Au-O bonding. The nanohybrid sorbent was packed in an organic filter along with a syringe and applied to the microextraction of triazine herbicides with the help of an injection pump. The collected hexane eluate was concentrated and directly injected into a HPLC column for quantification...
June 23, 2018: Mikrochimica Acta
Shuai Li, Wenbin Hua, Kun Wang, Yong Gao, Songfeng Chen, Wei Liu, Yu Song, Xinghuo Wu, Ji Tu, Liang Kang, Kangcheng Zhao, Liming Xiong, Yukun Zhang, Cao Yang
Autophagy dysfunction has been observed in intervertebral disc degeneration (IVDD) cells, a main contributing factor to cell death, but the precise role of autophagy during IVDD is still controversial. This study aimed to investigate the role of autophagy involved in the pathogenesis of human IVDD and determine the signal transduction pathways responsible for compression-induced autophagy in human nucleus pulposus (NP) cells. Autophagy, suppressing the induction of apoptosis, was activated in NP cells exposed to compression...
September 1, 2018: Experimental Cell Research
Jun Li, Xiaoyan Zhu, Kuai Yu, Haijing Jiang, Yizhi Zhang, Biqi Wang, Xuezhen Liu, Siyun Deng, Jie Hu, Qifei Deng, Huizhen Sun, Huan Guo, Xiaomin Zhang, Weihong Chen, Jing Yuan, Meian He, Yansen Bai, Xu Han, Bing Liu, Chuanyao Liu, Yanjun Guo, Bing Zhang, Zhihong Zhang, Frank B Hu, Wenjing Gao, Liming Li, Mark Lathrop, Catherine Laprise, Liming Liang, Tangchun Wu
BACKGROUND: Aging is related to an increased risk of morbidity and mortality and is affected by environmental factors. Exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with adverse health outcomes; but the association of such exposure with DNA methylation aging, a novel aging marker, is unclear. OBJECTIVES: Our aim was to investigate the association of PAH exposure with methylation aging. METHODS: We trained and validated a methylation age predictor suitable for Chinese populations using whole blood methylation data in 989 Chinese and 160 Caucasians...
June 2018: Environmental Health Perspectives
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