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Mako Fukano, Toru Fukubayashi, Scott Arthur Banks
The ankle joint, including the talocrural and subtalar joints, plays an important role in human locomotion. Sex differences in walking patterns among young and old adults have been studied; however, little information exists on sex-based variations in talocrural and subtalar joint kinematics during walking. Thus, the purpose of this study was to investigate sex-based differences in the talocrural and subtalar joint kinematics during walking. We obtained lateral fluoroscopic images from 10 male and 7 female healthy volunteers during stance phase, and determined the three-dimensional bone orientations using 3D-2D model-image registration techniques to compare sex-specific differences...
August 4, 2018: Human Movement Science
Yoshiki Moriizumi, Kazuhito V Tabata, Rikiya Watanabe, Tomohiro Doura, Mako Kamiya, Yasuteru Urano, Hiroyuki Noji
We developed a novel hybrid cell reactor system via functional fusion of single Escherichia coli protoplast cells, that are deficient in cell wall and expose plasma membrane, with arrayed lipid bilayer chambers on a device in order to incorporate the full set of cytosolic and membrane constituents into the artificial chambers. We investigated gene expression activity to represent the viability of the hybrid cell reactors: over 20% of hybrid cells showed gene expression activity from plasmid or mRNA. This suggests that the hybrid cell reactors retained fundamental activity of genetic information transduction...
August 6, 2018: Scientific Reports
Patrycja Makoś, Andrzej Przyjazny, Grzegorz Boczkaj
The paper presents novel nonionic and hydrophobic deep eutectic solvents which were synthesized from natural compounds, i.e., thymol, ±camphor, decanoic and 10-undecylenic acids. Fundamental physicochemical properties of the synthesized deep eutectic solvents were determined, followed by their application as extractants in ultrasound-assisted dispersive liquid-liquid microextraction to isolate and enrich polycyclic aromatic hydrocarbons from aqueous samples characterized by a complex matrix. The final determination was carried out by gas chromatography-mass spectrometry...
July 27, 2018: Journal of Chromatography. A
Chika Kubota, Takashi Okada, Mako Morikawa, Yukako Nakamura, Aya Yamauchi, Masahiko Ando, Tomoko Shiino, Masako Ohara, Satomi Murase, Setsuko Goto, Atsuko Kanai, Tomoko Masuda, Branko Aleksic, Norio Ozaki
This study aimed to assess the situation of postpartum depression and maternal bonding in Nagoya, a city distant from the epicenter of the Great East Japan Earthquake that occurred on March 11, 2011. Among the participants at 1 month after childbirth between March 11, 2010 and March 10, 2013 (n = 188), 152 fully responded to the Edinburgh Postnatal Depression Scale (EPDS) and Mother-Infant Bonding Questionnaire (MIBQ). They were divided into pre-quake (n = 58), and 0-6, 6-12, 12-18, and 18-24 months after the earthquake groups (n = 20, 26, 29, and 19, respectively)...
August 2, 2018: Scientific Reports
Mako Fukano, Takayuki Inami, Kento Nakagawa, Takaya Narita, Shigeo Iso
Prolonged running results in lowering of the foot arch and a low arch is associated with subsequent chronic injuries. Foot posture alteration and recovery following a marathon run remain unknown. Therefore, the present study aimed to evaluate foot posture alteration following a full marathon run. The three-dimensional foot posture data of 11 collegiate runners were obtained using an optical foot scanner system before, and immediately, 1 day, 3 days, and 8 days after a full marathon. The navicular height and arch height ratio significantly decreased from before to immediately, 1 day, 3 days, and 8 days after the marathon (navicular height: before, 44...
July 23, 2018: European Journal of Sport Science
Lindsay Jane Millar, Matthew Banger, Philip John Rowe, Mark Blyth, Bryn Jones, Angus Maclean
Recently, systems have been developed to improve alignment of unicompartmental knee arthroplasty (UKA) implants, although improvement in function has been difficult to document. The MAKO RIO robotic surgery system has previously shown improvements in in knee flexion during weight acceptance (WA) in comparison to conventional methods at a one year follow up. This study aimed to determine if these improvements remained at five years follow up. Twenty five MAKO and 21 conventional knees were tested using three dimensional gait analysis to measure knee kinematics...
July 19, 2018: Gait & Posture
Takahiro Hamada, Mako Yako, Marina Minegishi, Mayuko Sato, Yasuhiro Kamei, Yuki Yanagawa, Kiminori Toyooka, Yuichiro Watanabe, Ikuko Hara-Nishimura
Stress granules, a type of cytoplasmic RNA granules in eukaryotic cells, are induced in response to various environmental stresses, including high temperature. However, how high temperatures induce the formation of these stress granules in plant cells is largely unknown. Here, we characterized the process of stress granule formation in Arabidopsis thaliana by combining live imaging and electron microscopy analysis. In seedlings grown at 22 °C, stress granule formation was induced at temperatures above a critical threshold level of 34 °C in the absence of transpiration...
July 20, 2018: Journal of Cell Science
Yuji Shimizu, Shimpei Sato, Yuko Noguchi, Jun Koyamatsu, Hirotomo Yamanashi, Miho Higashi, Mako Nagayoshi, Shin-Ya Kawashiri, Yasuhiro Nagata, Noboru Takamura, Takahiro Maeda
BACKGROUND: Age-related low-grade inflammation causing endothelial disruption influences sarcopenia, hypertension, and atherosclerosis. We reported previously that maintenance of muscle strength in elderly hypertensive men with high platelet levels is positively associated with subclinical atherosclerosis but not in those with low platelet levels. Since reduced tongue pressure is related to sarcopenia, tongue pressure may be associated with subclinical carotid atherosclerosis in hypertensive elderly subjects, and platelet levels may function as an indicator of the association between tongue pressure and subclinical carotid atherosclerosis...
July 18, 2018: Environmental Health and Preventive Medicine
Mako Hayase, Mieko Shimada
AIM: To elucidate the changes in the daily variation seen in the autonomic nervous system during pregnancy brought about by maternity yoga and to evaluate how maternal yoga affects stress and sleep. METHODS: A prospective, longitudinal study was conducted between January 2013 and December 2014. Pregnant women who were attending maternity yoga classes at Palmore Hospital between 20 and 23 weeks' gestation were enrolled as the yoga group, and a matched control group was also enrolled...
July 17, 2018: Journal of Obstetrics and Gynaecology Research
Aya Yamauchi, Takashi Okada, Masahiko Ando, Mako Morikawa, Yukako Nakamura, Chika Kubota, Masako Ohara, Satomi Murase, Setsuko Goto, Atsuko Kanai, Norio Ozaki
Background: The Highs scale has been developed to evaluate hypomanic symptoms in the first postpartum week. However, it has not been elucidated whether this scale is also applicable to pregnant women. To address this issue, we confirmed the factor structure, reliability, and validity of the Japanese version of the Highs scale for pregnant and postpartum women. Methods: 418 women provided effective responses to both the Highs scale and the Edinburgh Postnatal Depression Scale (EPDS) during early pregnancy (before week 25), late pregnancy (around week 36), at 5 days and at 1 month after delivery...
2018: Frontiers in Psychiatry
Mako Yasuda-Yamahara, Manuel Rogg, Kosuke Yamahara, Jasmin I Maier, Tobias B Huber, Christoph Schell
Podocytes are highly-specialized epithelial cells essentially required for the generation and the maintenance of the kidney filtration barrier. This elementary function is directly based on an elaborated cytoskeletal apparatus establishing a complex network of primary and secondary processes. Here, we identify the actin-bundling protein allograft-inflammatory-inhibitor 1 like (AIF1L) as a selectively expressed podocyte protein in vivo. We describe the distinct subcellular localization of AIF1L to actin stress fibers, focal adhesion complexes and the nuclear compartment of podocytes in vitro...
2018: PloS One
Satoshi Ida, Naoki Hiki, Takeaki Ishizawa, Yugo Kuriki, Mako Kamiya, Yasuteru Urano, Takuro Nakamura, Yasuo Tsuda, Yosuke Kano, Koshi Kumagai, Souya Nunobe, Manabu Ohashi, Takeshi Sano
Purpose: Postoperative pancreatic fistula is a serious and fatal complication of gastrectomy for gastric cancer. Blunt trauma to the parenchyma of the pancreas can result from an assistant's forceps compressing and retracting the pancreas, which in turn may result in pancreatic juice leakage. However, no published studies have focused on blunt trauma to the pancreas during laparoscopic surgery. Our aim was to investigate the relationship between compression of the pancreas and pancreatic juice leakage in a swine model...
June 2018: Journal of Gastric Cancer
Ryan C Rauck, Jason L Blevins, Michael B Cross
Bell et al.'s "Improved Accuracy of Component Positioning with Robotic-Assisted Unicompartmental Knee Arthroplasty: Data from a Prospective, Randomized Controlled Study" compared the accuracy of a robotic-assisted unicompartmental knee arthroplasty (UKA) using the MAKO Robotic Interactive Orthopedic Arm (RIO) system to a conventional UKA using standardized instrumentation. This review examines the authors' findings and their relevance to clinical practice. Bell et al. conclude that the MAKO RIO system leads to more accurate implantation of both the tibial and femoral components in UKA in the sagittal, coronal, and axial planes...
July 2018: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
Shohei Yoshida, Kosuke Yamahara, Shinji Kume, Daisuke Koya, Mako Yasuda-Yamahara, Naoko Takeda, Norihisa Osawa, Masami Chin-Kanasaki, Yusuke Adachi, Kenji Nagao, Hiroshi Maegawa, Shin-Ichi Araki
Extending healthy lifespan is an emerging issue in an aging society. This study was designed to identify a dietary method of extending lifespan, promoting renoprotection, and preventing muscle weakness in aged mice, with a focus on the importance of the balance between dietary essential (EAAs) and nonessential amino acids (NEAAs) on the dietary restriction (DR)-induced antiaging effect. Groups of aged mice were fed ad libitum, a simple DR, or a DR with recovering NEAAs or EAAs. Simple DR significantly extended lifespan and ameliorated age-related kidney injury; however, the beneficial effects of DR were canceled by recovering dietary EAA but not NEAA...
June 25, 2018: Aging Cell
Hideaki Kondo, Keiko Tanio, Yuki Nagaura, Mako Nagayoshi, Chikage Mitoma, Masutaka Furue, Takahiro Maeda
PURPOSE: Patients with Yusho, a condition caused by exposure to dioxins and dioxin-like compounds, have diverse mental and physical complaints. However, the relationship between dioxins and sleep disorders has not yet been examined. This cross-sectional study was designed to investigate problems associated with sleep among patients with Yusho. METHODS: A total of 140 participants (52.9% men, average age: 67.1 ± 12.2 years) were examined using questionnaires and medical interviews by an expert on sleep medicine...
June 13, 2018: Environmental Research
Wakana Izumi, Yuko Takuma, Ryo Ebihara, Wataru Mizunoya, Ryuichi Tatsumi, Mako Nakamura
Myogenesis is precisely proceeded by myogenic regulatory factors. Myogenic stem cells are activated, proliferated and fused into a multinuclear myofiber. Pax7, paired box 7, one of the earliest markers during myogenesis. It has been reported that Pax7 regulates the muscle marker genes, Myf5 and MyoD toward differentiation. The possible roles of Pax7 in myogenic cells have been well researched. However, it has not yet been clarified if Pax7 itself is able to induce myogenic fate in nonmyogenic lineage cells...
June 13, 2018: Animal Science Journal, Nihon Chikusan Gakkaihō
Hiroaki Tabe, Kei Sukenobe, Toru Kondo, Atsunori Sakurai, Minako Maruo, Akari Shimauchi, Mitsuharu Hirano, Shin-Nosuke Uno, Mako Kamiya, Yasuteru Urano, Michio Matsushita, Satoru Fujiyoshi
We prepared a pair with a visible-absorbing donor dye and a near-infrared fluorescing acceptor dye. The donor and the acceptor were covalently linked close enough for Förster resonance energy transfer to occur. Under cryogenic conditions at 1.7 K, we observed the fluorescence excitation spectra of the individual pairs in a water matrix. We tested one rhodamine, two Bodipy, and one carbopyronine derivatives as the donor. Among these donors, Bodipy derivatives show the narrowest spectral width of the individuals with respect to the ensemble width...
July 12, 2018: Journal of Physical Chemistry. B
Joshua D Bundy, Lydia A Bazzano, Dawei Xie, Janet Cohan, Jacqueline Dolata, Jeffrey C Fink, Chi-Yuan Hsu, Kenneth Jamerson, James Lash, Gail Makos, Susan Steigerwalt, Xue Wang, Katherine T Mills, Jing Chen, Jiang He
BACKGROUND AND OBJECTIVES: Previous studies suggest that tobacco, alcohol, and illicit drug use is associated with CKD. We examined the associations of substance use with CKD progression and all-cause mortality among patients with CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: The Chronic Renal Insufficiency Cohort Study is a prospective, longitudinal cohort study among 3939 participants with CKD in the United States. Self-reported tobacco smoking, alcohol drinking, marijuana use, and hard illicit drug (cocaine, heroin, or methamphetamine) use were obtained at baseline and annual follow-up visits...
July 6, 2018: Clinical Journal of the American Society of Nephrology: CJASN
Hideaki Ohtsubo, Yusuke Sato, Yuji Matsuyoshi, Takahiro Suzuki, Wataru Mizunoya, Mako Nakamura, Ryuichi Tatsumi, Yoshihide Ikeuchi
The data presented in this article are related to the research articles entitled "APOBEC2 negatively regulates myoblast differentiation in muscle regeneration" and "Data supporting possible implication of APOBEC2 in self-renewal functions of myogenic stem satellite cells: toward understanding the negative regulation of myoblast differentiation" (Ohtsubo et al., 2017a, 2017b) [1,2]. This article provides in vivo phenotypical data to show that Paired Box Transcription Factor 7 (Pax7)-positive cell number (per myofiber) is significantly lower in APOBEC2 (a member of apoB mRNA editing enzyme, catalytic polypeptide-like family)-knockout muscle than the control wild-type tissue at the same age of 8-wk-old in mice...
April 2018: Data in Brief
Tomoe Nakao, Mitsushige Nishikawa, Mako Hisakado, Toshihiko Kasahara, Takumi Kudo, Eijun Nishihara, Mitsuru Ito, Shuji Fukata, Hirotoshi Nakamura, Mitsuyoshi Hirokawa, Akira Miyauchi
Background: There is little information regarding the natural course of hypoechoic thyroid lesions that are probable or possible thyroid lymphoma based on fine needle aspiration cytology (FNAC) results. Methods: Sixty-five patients who were diagnosed as probable or possible thyroid lymphoma by ultrasonography (US) and FNAC were investigated. Forty-three patients with strong suspicion underwent thyroid surgery for the diagnosis at our hospital, and 22 patients were followed up with periodic US examination...
2018: Thyroid Research
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