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Health protection

X Q Ji, C H Zhu, H Y Song
Objective: To understand the healthy status of radiation workers on the staff in Nanjing, and to analysis the relationship between abnormal crystalline lens and its influencing factors. Methods: We described physical indicators including blood pressure (BP) 、blood sugar (BG) 、thyroid B ultrasound、crystalline lens、chromosome and so on among 3 349 radiation workers on the staff in the year 2016 from Jan 1 to Dec 31, and the abnormal results of crystalline lens were analyzed statistically. Results: The rate of abnormal BP、BG、WBC、Thyroid B ultrasound、crystalline lens was 19...
August 20, 2018: Chinese Journal of Industrial Hygiene and Occupational Diseases
Raymond C Rosen, Claus G Roehrborn, Michael J Manyak, Juan Manuel Palacios-Moreno, Timothy H Wilson, Zrinka Lulic, Francois Giuliano
AIMS: Five-α reductase inhibitor (5ARI) therapy has been associated with sexual dysfunction in some patients. This study assessed the impact of a fixed-dose combination of the 5ARI dutasteride 0.5 mg and the α1 -adrenoceptor antagonist tamsulosin 0.4 mg (DUT-TAM FDC) on Men's Sexual Health Questionnaire (MSHQ) domain scores in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH). METHODS: This was a post hoc analysis of a double-blind, randomized, placebo-controlled, parallel-group, multicenter study in sexually active patients, aged ≥50 years, with a confirmed clinical diagnosis of BPH...
October 13, 2018: International Journal of Clinical Practice
Ahmed E Arafa, Florian Anzengruber, Alshimaa M Mostafa, Alexander A Navarini
The striking rise in the Internet utilization worldwide has led to major changes in the methods of data collection and processing. Online surveying has been used to assess different health services, explore patients' perceptions and measure interventions. The discipline of dermatology is one of the fields that gained benefits from surveying patients and dermatologists online, however, some disadvantages such as the low response rate and participation bias were suggested. This review summarizes the applications of online surveying in dermatology and discusses the methods of enhancing response to online surveys...
October 13, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Stephen Chu-Sung Hu, Chi-Ling Lin, Hung-Pin Tu
BACKGROUND: Psoriasis is a common skin disease that has been recently found to be associated with various systemic inflammatory disorders. However, the association between psoriasis and gout has not been well defined. OBJECTIVE: We investigated whether there is an association between psoriasis, psoriatic arthritis and gout in a large population of patients in Taiwan. METHODS: A nationwide population-based cross-sectional study was performed using the Taiwanese National Health Insurance Research Database (NHIRD)...
October 14, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Mauro Finicelli, Tiziana Squillaro, Francesca Di Cristo, Anna Di Salle, Mariarosa Anna Beatrice Melone, Umberto Galderisi, Gianfranco Peluso
Metabolic syndrome (MetS) is defined as the co-occurrence of metabolic risk factors that includes insulin resistance, hyperinsulinemia, impaired glucose tolerance, type 2 diabetes mellitus, dyslipidemia, and visceral obesity. The clinical significance of MetS consists of identifying a subgroup of patients sharing a common physiopathological state predisposing to chronic diseases. Clinical and scientific studies pinpoint lifestyle modification as an effective strategy aiming to reduce several features accountable for the risk of MetS onset...
October 14, 2018: Journal of Cellular Physiology
Chen Ye, Orpheus M Butler, Ming Du, Wenzhi Liu, Quanfa Zhang
Riparian ecosystems are particularly prone to heavy metal (HM) contamination, acting as a sink for HMs coming from human activities upstream or on adjacent uplands. An advanced understanding of the spatio-temporal dynamics, environmental drivers and the likely sources of HM contamination in riparian soils will be necessary for the conservation of riparian ecosystems. Thus, we conducted a nine-year study across a 600 km stream gradient along the Yangtze river, which has come under immense pressure in recent years partly due to the establishment of the Three Gorges Dam (TGD), the largest hydropower dam in the world...
October 9, 2018: Science of the Total Environment
Elizabeth Lee Daugherty Biddison, Ruth Faden, Howard S Gwon, Darren P Mareiniss, Alan C Regenberg, Monica Schoch-Spana, Jack Schwartz, Eric S Toner
The threat of a catastrophic public health emergency causing life threatening illness or injury on a massive scale has prompted extensive federal, state, and local preparedness efforts. Modeling studies suggest that an influenza pandemic similar to that of 1918 would require ICU and mechanical ventilation capacity that is significantly greater than what is available. Several groups have published recommendations for allocating life-support measures during a public health emergency. Because there are multiple ethically permissible approaches to allocating scarce life-sustaining resources and because the public will bear the consequences of these decisions, knowledge of public perspectives and moral points of reference on these issues is critical...
October 11, 2018: Chest
Mats Hallgren, Thi-Thuy-Dung Nguyen, Andreas Lundin, Davy Vancampfort, Brendon Stubbs, Felipe Schuch, Rino Bellocco, Ylva Trolle Lagerros
Regular physical activity (PA) appears to protect against the emergence of depression, but prospective studies linked to clinician diagnoses of major depressive disorder (MDD) remain scarce. It is also unclear whether PA levels recommended for general health are prospectively related to depression onset. We explored these relationships in a cohort of adults followed over 13 years. In total, 43,863 Swedish adults were surveyed in 1997 and responses linked to clinician-diagnosed MDD obtained from specialist medical registers until 2010...
October 11, 2018: Preventive Medicine
Pedro Espitia-Pérez, Suelen Marin Albino, Lyda Espitia-Pérez, Hugo Brango, Helen da Rosa, Alexandre Kleber Silveira, Diogo Pompéu Moraes, Camila Cerveira, Moara Mingori, Camila Tiefensee Ribeiro, Daniel Pens Gelain, Carlos Eduardo Schnorr, José Cláudio Fonseca Moreira
Fish consumption and ubiquitous methylmercury (MeHg) exposure represent a public health problem globally. Micronutrients presented in fish affects MeHg uptake/distribution. Vitamin A (VitA), another fish micronutrient is used in nutritional supplementation, especially during pregnancy. However, there is no information about the health effects arising from their combined exposure. The present study aimed to examine the effects of both MeHg and retinyl palmitate administered to pregnant and lactating rats. Thirty Wistar female rats were orally supplemented with MeHg (0,5 mg/Kg/day) and retinyl palmitate (7500 µg RAE1 /Kg/day), either individually or in combination from the gestational day 0 to weaning...
October 11, 2018: Neurotoxicology
Da Hyun Kim, Woo-Chang Chung, Su-Hyun Chun, Ji Ho Han, Moon Jung Song, Kwang-Won Lee
Influenza A virus (IAV) infection is a global public health concern. It causes respiratory diseases ranging from mild illness to fatal disease. Natural killer (NK) cells are an innate immune component that kill infected cells and secrete cytokines to modulate the adaptive immune system; they constitute the first-line defense and play important roles in controlling IAV infection. This study evaluated the effect of daily administration of heat-treated Lactobacillus plantarum nF1-fortified yogurt on immunity and protection against IAV infection...
October 10, 2018: Journal of Dairy Science
Nipapun Kungskulniti, Siriwan Pitayarangsarit, Stephen L Hamann
BACKGROUND: This study reports stakeholders' ratings, and perceived gaps in World Health Organization's (WHO) Framework Convention on Tobacco Control (FCTC) Article 8 implementation in Thailand viewed against WHO's Guidelines for Article 8 and to inform action in preparing the 2017 Tobacco Product Control Act. METHODS: Stakeholder ratings of Guideline provisions of Article 8 on a three-tiered scale of implementation from understanding to effectiveness and efficiency were used to identify gaps in enforcement and compliance important to success in meeting Article 8 goals...
June 3, 2018: International Journal of Health Policy and Management
Bolaji Samson Aregbeshola, Samina Mohsin Khan
BACKGROUND: There is high reliance on out-of-pocket (OOP) health payments as a means of financing health system in Nigeria. OOP health payments can make households face catastrophe and become impoverished. The study aims to examine the financial burden of OOP health payments among households in Nigeria. METHODS: Secondary data from the Harmonized Nigeria Living Standard Survey (HNLSS) of 2009/2010 was utilized to assess the catastrophic and impoverishing effects of OOP health payments on households in Nigeria...
March 10, 2018: International Journal of Health Policy and Management
Ole F Norheim
How can evidence from economic evaluations of the type the Disease Control Priorities project have synthesized be translated to better priority setting? This evidence provides insights into how investing in health, particularly though priority interventions and expanded access to health insurance and prepaid care, can not only save lives but also help alleviate poverty and provide financial risk protection. The article discusses some of the relevant factors needed to develop a Theory of Change for translating economic evidence to better priority setting within countries, and proposes some key strategic choices that are necessary to achieve the desired outputs and outcomes...
June 30, 2018: International Journal of Health Policy and Management
Tamar Berman, Zohar Barnett-Itzhaki, Rachel Axelrod, Lital Keinan-Boker, Tal Shimony, Rebecca Goldsmith, Thomas Göen, Haim Geva, Laura Rosen
BACKGROUND: Environmental tobacco smoke (ETS) exposure in infants and children causes more frequent and severe asthma attacks, respiratory infections, ear infections, and sudden infant death syndrome. The aim of this study was to measure ETS exposure in children in Israel (ages 4-11 years) using urinary cotinine measurements, in order to compare exposure levels to other international populations, and to assess predictors of ETS exposure in children in Israel. METHODS: A subset of children who participated in the National Health and Nutrition Survey (RAV- MABAT) in 2015-2016 were invited to participate in the Second Israel Biomonitoring Survey...
October 10, 2018: Environment International
Brian Lovell, Mark A Wetherell
Affiliate stigma is one risk factor for psychological distress in familial caregivers. Few studies however, and none involving caregivers in the UK and US, have explored caregivers' characteristics and family constellation variables as risk and protective factors for affiliate stigma. This study aimed to fill this gap. Moreover, we believe this study is only second to explore these relationships among caregivers of children with autism spectrum disorder (ASD), a group particularly vulnerable to affiliate stigma...
September 22, 2018: Psychiatry Research
Suat Sari, F Betül Kaynak, Sevim Dalkara
BACKGROUND: Currently available antiepileptic drugs offer limited symptomatic treatment and fail to cure more than 30% of the epileptic seizures. (Arylalkyl)azoles are a class of anticonvulsants including nafimidone and loreclezole. Here, we report the design and synthesis of new (arylalkyl)azoles in N-[1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethylidene]hydroxylamine ester structure, their anticonvulsant screening and in silico prediction studies of their pharmacokinetic properties...
June 23, 2018: Pharmacological Reports: PR
Shaorong Luan, Solange Muhayimana, Jiuyong Xu, Xianfei Zhang, Ciying Xiao, Qingchun Huang
Emamectin benzoate (EMB) toxicity contributes a potential risk to environment and human health. To investigate the effect of α-tocopherol (VitE) and dithiothreitol (DTT) in ameliorating EMB-induced cytotoxicity in human K562 cells, in vitro cultured human K562 cells were incubated with different concentrations of EMB in supplement with VitE and DTT when the cells were in the logarithmic phase. Next, the cell growth inhibition was evaluated using the MTT assay and cellular morphology observation. Reactive oxygen species (ROS) production was monitored using DCFH-DA probe and NF-κB signaling was determined using Western blotting...
October 10, 2018: Ecotoxicology and Environmental Safety
Chengliang Luo, Qiang Yang, Yuancai Liu, Shuanhu Zhou, Jiying Jiang, Russel J Reiter, Pallab Bhattacharya, Yongchun Cui, Hongwei Yang, He Ma, Jiemin Yao, Sean E Lawler, Xinmu Zhang, Jianfang Fu, Renato Rozental, Hany Aly, Mark D Johnson, E Antonio Chiocca, Xin Wang
Melatonin is a neurohormone associated with sleep and wakefulness and is mainly produced by the pineal gland in animals. Numerous physiological functions of melatonin have been demonstrated including anti-inflammation, suppressing neoplastic growth, circadian and endocrine rhythm regulation, and its potent antioxidant activity as well as its role in regeneration of various tissues including the nervous system, liver, bone, kidney, bladder, skin, and muscle, among others. In this review, we summarize the recent advances related to the multiple protective roles of melatonin receptor agonists, melatonin and N-acetylserotonin (NAS) in brain injury, liver damage, and bone health...
October 10, 2018: Free Radical Biology & Medicine
Carolina Barnett, Vera Bril, Ahmed M Bayoumi
INTRODUCTION: Health utilities are a preference-based method of valuing health states that are used in health care research, such as economic evaluations. There are limited health utility valuation data for patients with Myasthenia Gravis OBJECTIVES: To describe health utilities for patients with Myasthenia Gravis and different health states, using the EQ-5D-5L and SF-6D utility instruments, and to explore clinical and demographic determinants of utilities in this population. METHODS: Patients completed the EQ-5D-5L and SF-6D...
October 13, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
Stelliana Goutzamanis, Joseph Doyle, Peter Higgs, Margaret Hellard
With approximately 71 million people chronically infected worldwide and 1.75 million new infections in 2015, hepatitis C virus remains a significant public health concern. In developed countries hepatitis C transmission is predominantly driven by the sharing of injecting equipment, placing people who inject drugs (PWID) at the greatest risk of infection. It is estimated that approximately half of the PWID population are hepatitis C antibody positive. This article is protected by copyright. All rights reserved...
October 13, 2018: Journal of Viral Hepatitis
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