keyword
MENU ▼
Read by QxMD icon Read
search

Schizophrenic

keyword
https://www.readbyqxmd.com/read/27900577/neuroleptic-drugs-and-pacap-differentially-affect-the-mrna-expression-of-genes-encoding-pac1-vpac-type-receptors
#1
Marta Jóźwiak-Bębenista, Edward Kowalczyk
Several lines of evidence suggest that pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide playing an important role as a neuromodulator. It has been indicated that PACAP is associated with mental diseases, and that regulation of the PACAPergic signals could be a potential target for the treatment of such psychiatric states as schizophrenia. Recent studies have suggested that action of neuroleptic drugs is mediated not only by dopaminergic and serotonergic neurotransmission, but also via neuropeptides which may act both as neurotransmitters and as neuromodulators...
November 30, 2016: Neurochemical Research
https://www.readbyqxmd.com/read/27898171/hormesis-cellular-stress-response-and-neuroinflammation-in-schizophrenia-early-onset-versus-late-onset-state
#2
REVIEW
Vittorio Calabrese, James Giordano, Rosalia Crupi, Rosanna Di Paola, Martino Ruggieri, Rio Bianchini, Maria Laura Ontario, Salvatore Cuzzocrea, Edward J Calabrese
Abnormal redox homeostasis and oxidative stress have been proposed to play a role in the etiology of several neuropsychiatric spectrum disorders. Emerging interest has recently focused on markers of oxidative stress and neuroinflammation in schizophrenic spectrum disorders, at least in particular subgroups of patients. Altered expression of genes related to oxidative stress, oxidative damage to DNA, protein and lipids, as well as reduced glutathione levels in central and peripheral tissues could act synergistically, and contribute to the course of the disease...
November 29, 2016: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27888972/the-effect-of-yoga-on-functional-recovery-level-in-schizophrenic-patients
#3
Funda Kavak, Mine Ekinci
PURPOSE: The objective of this study is to determine the effect of yoga on functional recovery level in schizophrenic patients. MATERIALS AND METHODS: The study was conducted in quasi-experimental design with pretest-posttest control group. The population of the study consisted of schizophrenic patients with registered in Malatya and Elazığ Community Mental Health Centers and regularly going to these centers. The sample group of the study consisted of totally 100 patients including 50 patients in the experimental group and 50 patients in the control group who were specified through power analysis and chosen by using random sampling method from this population...
December 2016: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/27888954/the-effect-of-internalized-stigma-on-the-self-esteem-in-patients-with-schizophrenia
#4
Sibel Asi Karakaş, Ayşe Okanlı, Emine Yılmaz
AIM: This study has been conducted to determine the relationship between internalized stigma and self-esteem in patients with schizophrenia. MATERIALS AND METHODS: This study was conducted using 60 patients with schizophrenia who were diagnosed as schizophrenic according to the DSM-IV diagnostic criteria in the psychiatric clinics of hospitals in Erzurum. The data were collected using the "Questionnaire on Internalized Stigma of Mental Illness Scale" (ISMI) that determines the socio-demographic characteristics of patients, and the "Short Form of Self-Esteem Scale" (SF-SES)...
December 2016: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/27879309/brief-episodes-of-non-specific-psychosis-later-diagnosed-as-periodic-catatonia
#5
Victor Mark Tang, Helen Park
A 73-year-old woman was known to have discrete episodes of psychosis not otherwise specified that would require a brief admission to hospital and total remission following a short course of benzodiazepine or antipsychotic treatment. She had no underlying schizophrenic or affective disorder and was completely unimpaired in between episodes, which could last several years. She presented to us with psychotic symptoms but also noted to have many catatonic features, which were also present on previous presentations...
November 22, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27875318/1846g-a-polymorphism-of-cyp2d6-gene-and-extrapyramidal-side-effects-during-antipsychotic-therapy-among-russians-and-tatars-a-pilot-study
#6
Dmitriy A Sychev, Irina S Burashnikova, Ruslan E Kazakov
BACKGROUND: Сytochrome P450 CYP2D6 activity affects antipsychotic therapy safety. 1846G>A (CYP2D6*4) polymorphism frequency varies among different ethnic groups. METHODS: We studied 1846G>A polymorphism in Tatar and Russian schizophrenic patients taking different antipsychotics and association of 1846G>A polymorphism and extrapyramidal disorders (EPD) frequency in schizophrenic patients on haloperidol monotherapy in daily doses up to 20 mg. RESULTS: Heterozygous 1846GA genotype frequency among Tatars was lower (23...
December 1, 2016: Drug Metabolism and Personalized Therapy
https://www.readbyqxmd.com/read/27872693/obsessive-compulsive-disorder-in-hospitalized-patients-with-schizophrenia
#7
Mercedeh Samiei, Koorosh Hedayati, Arash Mirabzadeh Ardekani, Behrooz Dolatshahi, Reza Daneshmand, Roya Samadi
INTRODUCTION: Comorbid obsessive-compulsive disorder (OCD) has been reported among patients with schizophrenia in other countries. But, the literature is not well-documented on this issue in Iran (Persia). The present study aimed to investigate the prevalence and severity of OCD and some of its related factors in a group of patients with schizophrenia in Iran. METHODS: This is a cross-sectional study. A total of 150 hospitalized patients with schizophrenia were recruited at Razi Psychiatric Hospital in Tehran, Iran...
October 2016: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/27869767/clinical-decision-making-in-the-treatment-of-schizophrenia-focus-on-long-acting-injectable-antipsychotics
#8
Ludovic Samalin, Marion Garnier, Candy Auclair, Pierre-Michel Llorca
The purpose of this study was to identify clinician characteristics associated with higher prescription rates of long-acting injectable (LAI) antipsychotics, as well as the sources that influence medical decision-making regarding the treatment of schizophrenia. We surveyed 202 psychiatrists during six regional French conferences (Bordeaux, Lyon, Marseille, Nice, Paris, and Strasbourg). Data on the characteristics of practice, prescription rates of antipsychotic, and information sources about their clinical decisions were collected...
November 19, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27868463/postural-changes-in-different-stages-of-schizophrenia-is-associated-with-inflammation-and-pain-a-cross-sectional-observational-study
#9
Viviane Batista Cristiano, Michele Fonseca Vieira Szortyka, Maria Inês Lobato, Keila Maria Ceresér, Paulo Belmonte-de-Abreu
OBJECTIVES: To assess the relationship between posture and inflammatory response markers (C-reactive protein [CRP] and von Willebrand factor [vWF]) in schizophrenics. METHODS: Forty patients with stable schizophrenia were divided into early-stage (<10 years since first episode, n = 15) and late-stage (≥10 years since first episode, n = 25) groups. Both groups were compared to controls (n = 26). All participants underwent postural assessment by biophotogrammetry...
November 21, 2016: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/27863321/cognitive-dysfunction-correlates-with-elevated-serum-s100b-concentration-in-drug-free-acutely-relapsed-patients-with-schizophrenia
#10
Song Chen, Li Tian, Nan Chen, Meihong Xiu, Zhiren Wang, Guigang Yang, Chuanyue Wang, Fude Yang, Yunlong Tan
S100B, a biomarker of glial dysfunction and blood-brain barrier (BBB) disruption, has been proposed to be involved in the pathophysiology of schizophrenia. In the present study, we aimed at exploring the association of serum S100B levels with cognitive deficits using MATRICS Consensus Cognitive Battery (MCCB) in schizophrenia, by excluding the impact of antipsychotics. Sixty-two unmedicated patients with schizophrenia during their acute phases were divided into a drug-naïve group (n=34) and a drug-free group (n=28)...
September 22, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27859668/the-effects-of-olanzapine-treatment-on-brain-regional-glucose-metabolism-in-neuroleptic-naive-first-episode-schizophrenic-patients
#11
Hirofumi Yoshimuta, Masayuki Nakamura, Eisuke Kanda, Seigo Fujita, Kouzou Takeuchi, Toshiro Fujimoto, Yoshiaki Nakabeppu, Yasuaki Akasaki, Akira Sano
OBJECTIVE: The current study examined metabolic alterations associated with a positive response to olanzapine and identified brain regions associated with treatment-related improvement of symptoms in neuroleptic-naive first-episode schizophrenic patients using [(18) F]fluoro-deoxy-glucose positron emission tomography analysis. METHODS: Neuroleptic-naive first-episode schizophrenic patients who showed good or poor clinical responses to olanzapine were assessed using the Positive and Negative Syndrome Scale...
November 2016: Human Psychopharmacology
https://www.readbyqxmd.com/read/27856396/oestrogens-prolactin-hypothalamic-pituitary-gonadal-axis-and-schizophrenic-psychoses
#12
REVIEW
Anita Riecher-Rössler
Interest is growing in the potential effect of gonadal hormones, prolactin, and the hypothalamic-pituitary-gonadal axis in schizophrenic psychoses. Many studies from clinical, epidemiological, and fundamental research have confirmed that oestradiol, the main component of oestrogens, can have protective effects in schizophrenic psychoses. Furthermore, many patients with schizophrenic psychoses-even in the untreated prodromal stages-have hyperprolactinaemia and gonadal dysfunction, with oestrogen deficiency in women and testosterone deficiency in men...
November 11, 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/27854090/effective-and-cheap-behavioral-modification-therapy-to-manage-complicated-polydipsia-and-seizures-in-a-chronic-mental-health-institute
#13
Yen-Wen Chen, Weilun Chung, Ching-Kuan Wu, Shih-Pin Hsu, Ping-Tao Tseng
PURPOSE: Polydipsia is one of the most serious and complicated problems causing morbidity and mortality in chronic mental health institutes. The pathophysiology of polydipsia in chronic schizophrenia remains unclear; as a result, no effective methods exist to deal with this serious problem. This report describes a patient with schizophrenia with polydipsia and seizures who benefitted from a behavioral modification program at a chronic mental health institute. CASE REPORT: A 56-year-old schizophrenic man did not have a history of physical illnesses or seizures and developed seizures following polydipsia...
June 15, 2016: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/27847928/the-significance-of-the-personality-traits-of-schizophrenic-patients-and-their-therapists-for-the-therapeutic-relationship
#14
Anna Bielańska, Andrzej Cechnicki, Igor Hanuszkiewicz
OBJECTIVES: To analyse: 1) the associations between the therapists' and patients' assessments of the relationship, 2) the relationship between the personality traits of the therapists the personality traits of the patients and their assessments of the relationship, 3) the relationship between age, sex and the personality traits of both groups and their assessment of the relationship. METHODS: 34 patients in long-term psychotherapy and their 11 therapists were investigated...
2016: Psychiatria Polska
https://www.readbyqxmd.com/read/27847925/hollow-mask-illusion-is-it-really-a-test-for-schizophrenia
#15
Hubert M Wichowicz, Sławomir Ciszewski, Krzysztof Żuk, Anna Rybak-Korneluk
OBJECTIVES: The aim of the study was an assessment of the phenomenon of depth perception in schizophrenic patients compared to healthy subjects. METHODS: We conducted a comparison erroneous assessment of the concave side of the mask as convex, using the popular website presenting rotating Charlie Chaplin's mask. The study was performed in patients hospitalized at the Stanisław Kryzan Psychiatric Hospital in Starogard Gdanski diagnosed with paranoid and undifferentiated schizophrenia based on ICD-10 criteria and control group matched for age and education; each group included 58 subjects...
2016: Psychiatria Polska
https://www.readbyqxmd.com/read/27847924/the-sense-of-body-ownership-in-schizophrenia-research-in-the-rubber-hand-illusion-paradigm
#16
Beata Mirucka
OBJECTIVES: The aim of the research was to explore the susceptibility to disturbances in one's sense of body ownership induced in patients with schizophrenia. The research questions were: 1) Is Rubber Hand Illusion (RHI) significantly more intense in a group of patients with schizophrenia than in a group of patients without a diagnosed mental illness? 2) Is there a correlation between disturbances in the sense of body ownership and the personality organization level, reflected in defense mechanisms? 3) Do the disturbances in the sense of body ownership correlate with the most common defense mechanisms? METHODS: 64 people took part in the study, including 31 patients with diagnosed schizophrenia, according to ICD-10 (93...
2016: Psychiatria Polska
https://www.readbyqxmd.com/read/27847923/stages-of-the-clinical-course-of-schizophrenia-staging-concept
#17
REVIEW
Paweł Wójciak, Agnieszka Remlinger-Molenda, Janusz Rybakowski
Clinical staging is a tool useful in medical sciences. It assumes the presence of three key elements. Firstly, pathologic indices are progressing in subsequent stages. Secondly, the patients in the individual stages present similar pathological changes. Thirdly, treatment should be most effective in the earlier stages. Such model is particularly well established in the treatment of malignancies. Staging is useful here to define prognosis, to evaluate the results of treatment, facilitate the exchange and comparison of information among treatment centres...
2016: Psychiatria Polska
https://www.readbyqxmd.com/read/27846438/mapping-autobiographical-memory-in-schizophrenia-clinical-implications
#18
REVIEW
J J Ricarte, L Ros, J M Latorre, E Watkins
Increasing evidence suggests that impaired autobiographical memory (AM) mechanisms may be associated with the onset and maintenance of psychopathology. However, there is not yet a comprehensive review of the components of autobiographical memory in schizophrenic patients. The first aim of this review is a synthesis of evidence about the functioning of AM in schizophrenic patients. The main autobiographical elements reviewed in schizophrenic patients include the study of overgeneral memory (form); self-defining memories (contents); consciousness during the process of retrieval (awareness), and the abnormal early reminiscence bump (distribution)...
November 9, 2016: Clinical Psychology Review
https://www.readbyqxmd.com/read/27846195/genome-wide-association-study-of-paliperidone-efficacy
#19
Qingqin Li, Nathan E Wineinger, Dong-Jing Fu, Ondrej Libiger, Larry Alphs, Adam Savitz, Srihari Gopal, Nadine Cohen, Nicholas J Schork
OBJECTIVE: Clinical response to the atypical antipsychotic paliperidone is known to vary among schizophrenic patients. We carried out a genome-wide association study to identify common genetic variants predictive of paliperidone efficacy. METHODS: We leveraged a collection of 1390 samples from individuals of European ancestry enrolled in 12 clinical studies investigating the efficacy of the extended-release tablet paliperidone ER (n1=490) and the once-monthly injection paliperidone palmitate (n2=550 and n3=350)...
November 11, 2016: Pharmacogenetics and Genomics
https://www.readbyqxmd.com/read/27843322/the-reduction-of-csf-tumor-necrosis-factor-alpha-levels-in-schizophrenia-no-correlations-with-psychopathology-and-coincident-metabolic-characteristics
#20
Haibing Zhu, Danfeng Wang, Xiuqin Liu
AIM: The aim of this study was to assess whether tumor necrosis factor alpha (TNF-α) levels are correlated with the behavioral syndrome of schizophrenia and/or metabolic abnormalities. METHODS: Sixty patients with first-onset schizophrenia were recruited. The concentrations of TNF-α in the cerebrospinal fluid (CSF) were determined in 22 schizophrenia patients and ten patients with nonsuppurative appendicitis using a radioimmunoassay. Physiological characteristics such as fasting blood glucose, fasting insulin, triglycerides, corrected QT interval, waist circumference, and body mass index were measured prior to CSF collection...
2016: Neuropsychiatric Disease and Treatment
keyword
keyword
17167
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"