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Inhalant allergy

Sofie Ravall, Susanna Simberg
OBJECTIVES: Singers have reported higher prevalence of vocally harmful behaviors, vocal symptoms, and voice disorders than nonsingers have. The purpose of this study was to investigate the prevalence of voice disorders among choir singers and to discover the risk factors associated with voice disorders. Another purpose was to explore the choir singers' knowledge about the anatomy and physiology of the voice, and voice ergonomics. METHODS: Three hundred and fifteen adult choir singers, 65% women, and 35% men, completed a web-questionnaire...
August 10, 2018: Journal of Voice: Official Journal of the Voice Foundation
Jung-Hyun Kim, Sae-Hoon Kim, Heung-Woo Park, Sang-Heon Cho, Yoon-Seok Chang
Background: Oral allergy syndrome (OAS) is a type of allergic reaction that mainly occurs on oral contact with raw fruit, vegetables, or nuts. The most common type of OAS is birch pollen-related food allergy. Although OAS is a common food allergy in adults, only few epidemiologic studies have been reported in Korea. Here we investigate the prevalence and triggers of birch pollen-related food allergy. Methods: We conducted a retrospective chart review of 1,427 patients who underwent a skin prick test for inhalant allergens at the Asthma and Allergy Clinic in Seoul National University Bundang Hospital from January 2011 to December 2016...
August 13, 2018: Journal of Korean Medical Science
Cecilia Gretchen Navarro-Locsin, Margaret Lim-Jurado
Background: There is a large global variation in sensitization patterns to aeroallergens due to differences in climate, urbanization, and lifestyle. Knowledge of the most common inhalant allergens is important for appropriate prevention and management of allergic rhinitis (AR). Objective: This study aims to provide data on aeroallergen sensitization patterns and associated comorbid diseases of adult Filipinos with AR. Methods: Medical records of adult Filipinos seen in an Otolaryngology-Allergy Clinic from January 2011 to 2016 were reviewed...
July 2018: Asia Pacific Allergy
Jarmila Čelakovská, Josef Bukač, Karel Ettler, Jaroslava Vaneckova, Kvetuse Ettlerova
Background: In adult patients suffering from atopic dermatitis (AD), studies investigating the co-prevalence of AD and food allergy are still scarce, and exact data are not available. Aims and Objectives: To evaluate the occurrence of food allergy to peanuts in significant relation to food hypersensitivity, inhalant allergy and to asthma bronchial and rhinitis. Materials and Methods: Altogether 332 patients of AD 14 year or older were included in the study...
July 2018: Indian Journal of Dermatology
Hevertton Luiz Bozzo Silva Santos, Silvia de Souza E Silva, Estela de Paula, Lilian Pereira-Ferrari, Liya Mikami, Carlos Antônio Riedi, Herberto José Chong-Neto, Nelson Augusto Rosário
OBJECTIVE: To verify the relationship between polymorphisms of the vitamin D receptor gene (VDR), clinical findings, and serum vitamin D (VD) levels in asthmatics. METHODS: A cross sectional study of 77 children aged 7 to 14 years old, who were attended at a specialized clinic. The children were divided into 3 groups: asthmatics who had been using inhaled corticosteroids (ICS) for more than one year; asthmatics who had not been using ICS; non-asthmatics, and children without allergies (according to the International Study of Asthma and Allergies in Childhood -- ISAAC)...
July 26, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Shaista Khan, Muhammad Hassan Khaskheli, Ghulam Nabi, Bikha Ram Deverajani, Naima Memon, Ghulam Abbas Shar
Wheat allergy specifically refers to the adverse reaction involving IgE antibody to one or more protein fraction of wheat such as albumin, globulin, gliadin and glutenin (gluten). The majority of IgE-mediated reactions to wheat involve albumin and globulin fraction while gluten (gliadin & glutenin) also cause allergy (Celiac disease). Allergic reactions to wheat may be caused by ingestion of wheat containing foods or inhalation of flour (Bakers asthma). The present study was an effort to explore the antibody response of different proteins present in wheat...
July 2018: Pakistan Journal of Pharmaceutical Sciences
Vijaya Knight, Molly L Wolf, Anita Trikha, Douglas Curran-Everett, Melissa Hiserote, Ronald J Harbeck
Although skin-prick testing (SPT) is commonly used by allergists in the evaluation of allergy, in-vitro testing for specific IgE (sIgE) is an attractive alternate because it can be performed remotely and is of utility when SPT is contraindicated, as in patients on anti-histamines, or with dermatitis or severe eczema. It is, however, necessary to determine the extent of correlation between the in-vitro and in-vivo methods. In this study, we examined the qualitative concordance between SPT and sIgE as measured on the HYTEC™288 platform for 10 commonly encountered inhalant allergens in 232 subjects, and analysed the performance characteristics for the HYTEC™288...
July 19, 2018: Journal of Immunological Methods
S Hashimoto, L H Rijssenbeek-Nouwens, K B Fieten, E J Weersink, E H Bel
BACKGROUND: High-altitude climate therapy has been shown to benefit patients with severe asthma but it is not known which patients benefit most from this treatment. In the current study we aimed to identify clinical, functional and inflammatory predictors of favourable outcome of high-altitude climate therapy. METHODS: This is a secondary analysis of a prospective cohort including 136 adult patients with a diagnosis of severe refractory asthma, referred to the Dutch Asthma Centre in Davos (1600 metres above sea level), Switzerland...
July 2018: Netherlands Journal of Medicine
Johannes Waage, Marie Standl, John A Curtin, Leon E Jessen, Jonathan Thorsen, Chao Tian, Nathan Schoettler, Carlos Flores, Abdel Abdellaoui, Tarunveer S Ahluwalia, Alexessander C Alves, Andre F S Amaral, Josep M Antó, Andreas Arnold, Amalia Barreto-Luis, Hansjörg Baurecht, Catharina E M van Beijsterveldt, Eugene R Bleecker, Sílvia Bonàs-Guarch, Dorret I Boomsma, Susanne Brix, Supinda Bunyavanich, Esteban G Burchard, Zhanghua Chen, Ivan Curjuric, Adnan Custovic, Herman T den Dekker, Shyamali C Dharmage, Julia Dmitrieva, Liesbeth Duijts, Markus J Ege, W James Gauderman, Michel Georges, Christian Gieger, Frank Gilliland, Raquel Granell, Hongsheng Gui, Torben Hansen, Joachim Heinrich, John Henderson, Natalia Hernandez-Pacheco, Patrick Holt, Medea Imboden, Vincent W V Jaddoe, Marjo-Riitta Jarvelin, Deborah L Jarvis, Kamilla K Jensen, Ingileif Jónsdóttir, Michael Kabesch, Jaakko Kaprio, Ashish Kumar, Young-Ae Lee, Albert M Levin, Xingnan Li, Fabian Lorenzo-Diaz, Erik Melén, Josep M Mercader, Deborah A Meyers, Rachel Myers, Dan L Nicolae, Ellen A Nohr, Teemu Palviainen, Lavinia Paternoster, Craig E Pennell, Göran Pershagen, Maria Pino-Yanes, Nicole M Probst-Hensch, Franz Rüschendorf, Angela Simpson, Kari Stefansson, Jordi Sunyer, Gardar Sveinbjornsson, Elisabeth Thiering, Philip J Thompson, Maties Torrent, David Torrents, Joyce Y Tung, Carol A Wang, Stephan Weidinger, Scott Weiss, Gonneke Willemsen, L Keoki Williams, Carole Ober, David A Hinds, Manuel A Ferreira, Hans Bisgaard, David P Strachan, Klaus Bønnelykke
Allergic rhinitis is the most common clinical presentation of allergy, affecting 400 million people worldwide, with increasing incidence in westernized countries1,2 . To elucidate the genetic architecture and understand the underlying disease mechanisms, we carried out a meta-analysis of allergic rhinitis in 59,762 cases and 152,358 controls of European ancestry and identified a total of 41 risk loci for allergic rhinitis, including 20 loci not previously associated with allergic rhinitis, which were confirmed in a replication phase of 60,720 cases and 618,527 controls...
August 2018: Nature Genetics
Anna Bednarek, Anna Bodajko-Grochowska, Małgorzata Bartkowiak-Emeryk, Robert Klepacz, Janusz Ciółkowski, Danuta Zarzycka, Andrzej Emeryk
Introduction: Asthma control is an important measure of disease stabilization, which is linked to the treatment and lifestyle recommendations. Aim: To assess the impact of selected factors on asthma control in adolescents, as assessed using the Asthma Control Test (ACT™). Material and methods: The prospective study included 100 asthma patients aged between 12 and 19. Asthma was assessed in three consecutive follow-up visits spaced 3 months apart, using the standardized ACT™ questionnaire...
June 2018: Postȩpy Dermatologii i Alergologii
Arshad H Rahmani, Ahmad Almatroudi, Ali Yousif Babiker, Amjad A Khan, Mohammed A Alsahly
BACKGROUND: Cement contains various types of chemicals in addition to lime and silica, and such chemicals cause different health complications and pathogenesis in addition to respiratory disorders. The most important occupational hazards for cement workers are allergy and complication related to respiratory system. AIM: The current study was performed by analysing the questionnaire distributed among the workers and also by the sputum collected from them to study the general health conditions and other life activities...
June 20, 2018: Open Access Macedonian Journal of Medical Sciences
S B Batmaz
INTRODUCTION AND OBJECTIVES: Atopic dermatitis (AD) is an eczematous skin disease. Our aim was to evaluate the clinical and laboratory findings of children with AD and identify the higher responsive group to moisturizers. MATERIALS AND METHODS: Total and specific IgE, eosinophil count, prick/patch test results of patients with AD were retrospectively analyzed. The presentation SCORAD was compared between the demographic and clinical subgroups. The SCORAD change (presentation to third month) between the intrinsic and extrinsic groups was compared...
July 3, 2018: Allergologia et Immunopathologia
Moumita B Sarkar, Gaurab Sircar, Nandini Ghosh, Abhishek K Das, Kuladip Jana, Angira Dasgupta, Swati G Bhattacharya
Papaya has been reported to elicit IgE-mediated hypersensitivity via pollen inhalation and fruit consumption. Certain papaya sensitive patients with food allergy were found to experience recurrent respiratory distresses even after quitting the consumption of fruits. This observation prompted us to investigate the allergens commonly present in fruits and pollen grains of papaya. A discovery approach consisting of immunoproteomic detection followed by molecular characterization led to the identification of a novel papaya allergen designated as Cari p 1...
2018: Frontiers in Plant Science
Eugene Wong, Aneeza W Hamizan, Raquel Alvarado, Carolyn A Orgain, Larry Kalish, Raymond Sacks, Richard J Harvey
PURPOSE: Middle turbinate head edema has recently been found to have high specificity for diagnosis of inhalant allergy. However, subtle mucosal edema can be difficult to appreciate under white light endoscopy. Narrow band imaging (NBI) has the potential to demonstrate edema by identifying reduced mucosal vascularity and improve sensitivity for the detection of mucosal edema. Narrow band imaging was assessed to determine its utility in objectifying mucosal edema. MEATERIALS AND METHODS: A cross-sectional diagnostic study was performed on patients with edematous mucosa of the middle turbinate head...
June 22, 2018: American Journal of Otolaryngology
Suriani Alimuddin, Iris Rengganis, Cleopas M Rumende, Siti Setiati
BACKGROUND: nowadays, specific IgE measurement has been conducted in Indonesia, however there is still lack of data regarding diagnostic test to detect inhalant allergen in patients with respiratory allergies.This study aimed to determine the accuracy of specific IgE test in diagnosing specific sensitization of inhalant allergen in patients with respiratory allergies. METHODS: this was a cross sectional study in patients with respiratory allergies and part of epidemiology study regarding to specific IgE sensitization in Allergy-Immunollogy Division, Cipto Mangunkusumo Hospital, Jakarta within November-December 2016...
April 2018: Acta Medica Indonesiana
Carl M Philpott, Sally Erskine, Claire Hopkins, Nirmal Kumar, Shahram Anari, Naveed Kara, Sankalp Sunkaraneni, Jaydip Ray, Allan Clark, Andrew Wilson, Sally Erskine, Carl Philpott, Allan Clark, Claire Hopkins, Alasdair Robertson, Shahzada Ahmed, Naveed Kara, Sean Carrie, Vishnu Sunkaraneni, Jaydip Ray, Shahram Anari, Paul Jervis, Jaan Panesaar, Amir Farboud, Nirmal Kumar, Russell Cathcart, Robert Almeyda, Hisham Khalil, Peter Prinsley, Nicolas Mansell, Mahmoud Salam, Jonathan Hobson, Jane Woods, Emma Coombes
BACKGROUND: Chronic rhinosinusitis (CRS) is a common disorder associated with other respiratory tract diseases such as asthma and inhalant allergy. However, the prevalence of these co-morbidities varies considerably in the existing medical literature and by phenotype of CRS studied. The study objective was to identify the prevalence of asthma, inhalant allergy and aspirin sensitivity in CRS patients referred to secondary care and establish any differences between CRS phenotypes. METHODS: All participants were diagnosed in secondary care according to international guidelines and invited to complete a questionnaire including details of co-morbidities and allergies...
June 27, 2018: Respiratory Research
Ioana Adriana Muntean, Ioana Corina Bocsan, Diana Deleanu
Wheat is the most commonly grown cereal. Immunological reaction to wheat may be IgE or T-cell- mediated. Asthma could be induced by inhaled flour or by exposure to allergens present in bakery products. In patients with IgE-mediated allergy to wheat proteins there is no specific therapy, except oral immunotherapy (OIT). There are few data regarding OIT with wheat protein in allergic patients. We present a case of a 32-yearold female patient, who worked for 5 years in wheat and bakery products industry, who developed an occupational asthma and chronic urticaria after flour inhalation or ingestion of foods that containit...
June 2018: Iranian Journal of Allergy, Asthma, and Immunology
Eun Lee, Young-Ho Kim, Hyun-Ju Cho, Ji-Sun Yoon, Sungsu Jung, Song-I Yang, Hyung Young Kim, Ji-Won Kwon, Ju-Hee Seo, Hyo Bin Kim, So Yeon Lee, Soo-Jong Hong
BACKGROUND: Bronchial hyperresponsiveness (BHR), one of the key features of asthma, shows a diverse natural course in school-aged children, but, studies on BHR phenotypes are lacking. OBJECTIVE: We classified BHR phenotypes according to onset age and persistence in children and investigated the characteristics and factors associated with each phenotype in a longitudinal study. METHODS: We analyzed 1,305 elementary school children from the Children's HEalth and Environmental Research (CHEER) study, a 4-year prospective follow-up study with 2-year intervals starting at a mean age of 7 years...
June 7, 2018: Annals of Allergy, Asthma & Immunology
Marsha D W Ward, Lisa B Copeland
Allergic diseases (atopy) include asthma, allergic rhinitis, conjunctivitis, and allergic sinusitis. It is estimated that up to 90% of asthmatics are atopic and have an allergy trigger for asthmatic episodes. In order to assess the risk of allergy induction associated with inhalation exposure, animal models of protein allergy have been developed. These models have been used both to identify proteins as allergens and to assess their relative potency. Often these research situations include allergens that are not well characterized or are unknown...
2018: Methods in Molecular Biology
Petr Panzner, Martina Vachová, Tomáš Vlas, Petra Vítovcová, Petra Brodská, Marek Malý
Background: The major sources of allergens in the indoor air include house dust mites, dander derived from domestic animals and rodents, cockroach, and several fungi. Mites are the main cause of allergies in some countries with a warmer climate, but the epidemiological significance of mite and cockroach allergens in Central Europe has not been established yet. Methods: We assessed sensitization profiles of allergy patients in a Central European region in regard to sensitization to mites and cockroach...
2018: Clinical and Translational Allergy
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