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https://www.readbyqxmd.com/read/27922197/variability-in-the-performance-characteristics-of-igg-anti-hev-assays-and-its-impact-on-reliability-of-seroprevalence-rates-of-hepatitis-e
#1
Maja Kodani, Nourine Ahmed, Alexandra Tejada-Strop, Amanda Poe, Maxine M Denniston, Jan Drobeniuc, Saleem Kamili
Hepatitis E is a major public health problem in developing countries and is increasingly being recognized as a cause of substantial sporadic viral hepatitis infections in industrialized countries. Variable rates of hepatitis E seroprevalence have been reported from the same geographic regions depending on the assay used. In this study, we evaluated the performance characteristics of four assays which included two commercial assays, Wantai HEV-IgG ELISA kit (Wantai, China) and DS-EIA-ANTI-HEV-G kit (DSI, Italy), one NIH-developed immunoassay (NIH-55K, Kuniholm et al...
December 6, 2016: Journal of Medical Virology
https://www.readbyqxmd.com/read/27877117/general-habit-propensity-relates-to-the-sensation-seeking-subdomain-of-impulsivity-but-not-obesity
#2
Anja Dietrich, Sanne de Wit, Annette Horstmann
According to dual-system theory, instrumental learning and performance depend on the balance between goal-directed and habitual action control. Overreliance on habits has been argued to characterize clinical conditions such as drug addiction or obsessive-compulsive disorder as well as obesity and excessive impulsivity. A tendency toward habitual action control in obesity has already been indicated in the food domain. However, impairments might not be restricted to eating behavior. This has been suggested by domain-general obesity-associated disturbances in executive function as well as alterations in corticostriatal circuits underlying the goal-directed and habitual systems...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27876742/-on-the-problem-of-voice-rehabilitation-in-the-case-of-unilateral-vocal-fold-paresis
#3
V V Shilenkova
BACKGROUND: Unilateral vocal fold paresis (UVFP) significantly deteriorates the patient's quality of life. The leading role in the rehabilitation of the patients presenting with UVFP belongs to stimulation therapy which consists in the activation of muscle re-innervation of the larynx and the compensatory mechanisms allowing to achieve the most complete closure of the vocal folds during phonation. AIM: The objective of the present study was the optimization of the conservative treatment of patients with UVFP...
2016: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/27873455/catalytic-asymmetric-reductive-condensation-of-n-h-imines-synthesis-of-c2-symmetric-secondary-amines
#4
Vijay N Wakchaure, Benjamin List
A highly diastereoselective and enantioselective Brønsted acid catalyzed reductive condensation of N-H imines was developed. This reaction is catalyzed by a chiral disulfonimide (DSI), uses Hantzsch esters as a hydrogen source, and delivers useful C2 -symmetric secondary amines.
November 22, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27870019/silica-uptake-and-release-in-live-and-decaying-biomass-in-a-northern-hardwood-forest
#5
Wim Clymans, Daniel J Conley, John J Battles, Patrick J Frings, Mary Margaret Koppers, Gene E Likens, Chris E Johnson
In terrestrial ecosystems, a large portion (20-80%) of the dissolved Si (DSi) in soil solution has passed through vegetation. While the importance of this "terrestrial Si filter" is generally accepted, few data exist on the pools and fluxes of Si in forest vegetation and the rate of release of Si from decomposing plant tissues. We quantified the pools and fluxes of Si through vegetation and coarse woody debris (CWD) in a northern hardwood forest ecosystem (Watershed 6, W6) at the Hubbard Brook Experimental Forest (HBEF) in New Hampshire, USA...
November 2016: Ecology
https://www.readbyqxmd.com/read/27869409/communication-skills-of-residents-to-families-with-down-syndrome-babies
#6
Derya G Dogan, Yesim Kutluturk, Meltem Kivilcim, Sinem K Canaloglu
BACKGROUND: Generally, pediatricians are the first health caregivers to deliver initial diagnosis of Down syndrome (DS) to the families. However, most of the parents are not satisfied with the contents and how they receive information when their child is born with DS. Pediatric residents should target educational interventions to help parents to overcome with these issues and to provide accurate information. The objective is to assess comfort levels and training requirements of pediatric residents to communicate with parents of babies born with Down syndrome...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27867131/neuronavigation-based-on-track-density-image-extracted-from-deterministic-high-definition-fiber-tractography-a-case-report
#7
Peng-Hu Wei, Fei Cong, Ge Chen, Ming-Chu Li, Xin-Guang Yu, Yu-Hai Bao
BACKGROUND: Diffusion tensor imaging(DTI)-based navigation is unable to resolve crossing fibers or to determine with accuracy the fanning, origin, and termination of fibers. It is important to improve the accuracy of localizing white matter fibers for improved surgical approaches. We propose a solution to this problem using navigation based on track density imaging(TDI)extracted from high definition fiber tractography(HDFT). CASE DESCRIPTION: A 28-year-old asymptomatic female patient with a left-lateral ventricle meningioma was enrolled in the present study...
November 17, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27861938/voice-outcome-and-voice-related-quality-of-life-after-surgery-for-pediatric-laryngotracheal-stenosis
#8
Bas Pullens, Marieke Hakkesteegt, Hans Hoeve, Marieke Timmerman, Koen Joosten
OBJECTIVES: To evaluate the long-term outcome of voice quality and voice-related quality of life after open airway surgery for pediatric laryngotracheal stenosis. STUDY DESIGN: Prospective cohort study. METHODS: Children under the age of 18 years at time of follow-up and with a history of open airway surgery for acquired laryngotracheal stenosis were included in this analysis. To assess voice-related quality of life, the pediatric voice handicap (pVHI) index was completed by the patients' parents...
November 9, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27830099/how-colposcopy-misses-invasive-cervical-cancer-a-case-report-from-the-improve-colpo-study
#9
Jeff Livingston, Emmanouil Papagiannakis
Colposcopy with biopsy is pivotal to cervical cancer prevention programs as it is called to identify the precancerous lesions on patients that screen positive. We present a cervical cancer case from IMPROVE-COLPO, a postmarketing, multicenter, two-arm observational study on US community colposcopy that collects outcomes with the adjunctive Dynamic Spectral Imaging (DSI) in its prospective arm. A 45-year-old woman was seen for suffering of heavy periods. She had cytology of Atypical Squamous Cells of Undetermined Significance (ASC-US) and was Human Papillomavirus (HPV) positive...
2016: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27811476/factors-involved-in-vocal-fatigue-a-pilot-study
#10
Evelien D'haeseleer, Mara Behlau, Laura Bruneel, Iris Meerschman, Anke Luyten, Stien Lambrecht, Mauriceia Cassol, Paul Corthals, Maryna Kryshtopava, Floris L Wuyts, Sofie Claeys, Kristiane Van Lierde
OBJECTIVE: The purpose of this retrospective study was to determine the vocal characteristics of a treatment-seeking population with the primary complaint of vocal fatigue (VF). METHODS: Forty-three men (mean age 42 years, range 19-69) and 145 women (mean age 34 years, range 18-68) were included. None of the subjects had received voice therapy or previous laryngeal surgery. A questionnaire, laryngeal and perceptual evaluations, aerodynamic and acoustic parameters, and the Dysphonia Severity Index (DSI) were used to determine vocal characteristics...
November 4, 2016: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/27810569/dignity-and-psychosocial-related-variables-in-advanced-and-non-advanced-cancer-patients-by-using-the-patient-dignity-inventory-italian-version-pdi-it
#11
Luigi Grassi, Anna Costantini, Rosangela Caruso, Serena Brunetti, Paolo Marchetti, Silvana Sabato, Maria Giulia Nanni
CONTEXT: The Patient Dignity Inventory (PDI) is a valid and reliable instrument to measure dignity, as a state of physical, mental, social and spiritual wellbeing in palliative care patients and an essential dimension for a comprehensive patient-centered approach OBJECTIVES: We examined the factor structure and the correlation of the Italian version of the PDI (PDI-IT) with psychosocial variables among advanced and non-advanced cancer outpatients in two Italian centers. METHODS: In a sample of 194 patients principal component analysis, reliability analysis (Cronbach's coefficient alpha), and correlation analysis of the PDI-IT were performed...
October 31, 2016: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/27802228/development-of-a-late-life-dementia-prediction-index-with-supervised-machine-learning-in-the-population-based-caide-study
#12
Timo Pekkala, Anette Hall, Jyrki Lötjönen, Jussi Mattila, Hilkka Soininen, Tiia Ngandu, Tiina Laatikainen, Miia Kivipelto, Alina Solomon
BACKGROUND AND OBJECTIVE: This study aimed to develop a late-life dementia prediction model using a novel validated supervised machine learning method, the Disease State Index (DSI), in the Finnish population-based CAIDE study. METHODS: The CAIDE study was based on previous population-based midlife surveys. CAIDE participants were re-examined twice in late-life, and the first late-life re-examination was used as baseline for the present study. The main study population included 709 cognitively normal subjects at first re-examination who returned to the second re-examination up to 10 years later (incident dementia n = 39)...
October 14, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27781491/feasibility-of-offline-head-neck-adaptive-radiotherapy-using-deformed-planning-ct-electron-density-mapping-on-weekly-cone-beam-computed-tomography
#13
Anantharaman Ayyalusamy, Subramani Vellaiyan, Subramanian Shanmugam
OBJECTIVE: The purpose of the study is to use deformable mapping of planning CT electron density values on weekly cone beam computed tomography (CBCT) to quantify the anatomical changes and determine the dose volume relationship in offline adaptive volumetric modulated arc therapy. METHODS: Ten patients treated with RapidArc plans who had weekly CBCTs were selected retrospectively. Planning CT was deformed to weekly CBCTs and the deformed contours were checked for any discrepancies...
October 26, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27776320/assessment-of-mechanical-behavior-of-pla-composites-reinforced-with-mg-micro-particles-through-depth-sensing-indentations-analysis
#14
S C Cifuentes, E Frutos, R Benavente, V Lorenzo, J L González-Carrasco
This work deals with the mechanical characterization by depth-sensing indentation (DSI) of PLLA and PLDA composites reinforced with micro-particles of Mg (up to 15wt%), which is a challenging task since the indented volume must provide information of the bulk composite, i.e. contain enough reinforcement particles. The composites were fabricated by combining hot extrusion and compression moulding. Physico-chemical characterization by TGA and DSC indicates that Mg anticipates the thermal degradation of the polymers but does not compromise their stability during processing...
September 21, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27775008/coordinated-regulation-of-endocannabinoid-mediated-retrograde-synaptic-suppression-in-the-cerebellum-by-neuronal-and-astrocytic-monoacylglycerol-lipase
#15
Xiaojie Liu, Yao Chen, Casey R Vickstrom, Yan Li, Andreu Viader, Benjamin F Cravatt, Qing-Song Liu
The endocannabinoid 2-arachidonoylglycerol (2-AG) mediates retrograde synaptic depression including depolarization-induced suppression of excitation (DSE) and inhibition (DSI). 2-AG is degraded primarily by monoacylglycerol lipase (MAGL), which is expressed in neurons and astrocytes. Using knockout mice in which MAGL is deleted globally or selectively in neurons or astrocytes, we investigated the relative contribution of neuronal and astrocytic MAGL to the termination of DSE and DSI in Purkinje cells (PCs) in cerebellar slices...
October 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27775007/coupling-of-carbon-and-silicon-geochemical-cycles-in-rivers-and-lakes
#16
Baoli Wang, Cong-Qiang Liu, Stephen C Maberly, Fushun Wang, Jens Hartmann
Carbon (C) and silicon (Si) biogeochemical cycles are important factors in the regulation of atmospheric CO2 concentrations and hence climate change. Theoretically, these elements are linked by chemical weathering and organism stoichiometry, but this coupling has not been investigated in freshwaters. Here we compiled data from global rivers and lakes in the United States of America and the United Kingdom, in order to characterize the stoichiometry between the biogeochemical cycles of C and Si. In rivers this coupling is confirmed by a significant relationship between HCO3(-)/Na(+) and DSi/Na(+), and DSi:HCO3(-) ratio can reflect the mineral source of chemical weathering...
October 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27743250/multimodal-analysis-to-predict-shunt-surgery-outcome-of-284-patients-with-suspected-idiopathic-normal-pressure-hydrocephalus
#17
Antti J Luikku, Anette Hall, Ossi Nerg, Anne M Koivisto, Mikko Hiltunen, Seppo Helisalmi, Sanna-Kaisa Herukka, Anna Sutela, Maria Kojoukhova, Jussi Mattila, Jyrki Lötjönen, Jaana Rummukainen, Irina Alafuzoff, Juha E Jääskeläinen, Anne M Remes, Hilkka Soininen, Ville Leinonen
OBJECTIVES: Optimal selection of idiopathic normal pressure hydrocephalus (iNPH) patients for shunt surgery is challenging. Disease State Index (DSI) is a statistical method that merges multimodal data to assist clinical decision-making. It has previously been shown to be useful in predicting progression in mild cognitive impairment and differentiating Alzheimer's disease (AD) and frontotemporal dementia. In this study, we use the DSI method to predict shunt surgery response for patients with iNPH...
October 14, 2016: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27742434/comparison-of-compressed-sensing-diffusion-spectrum-imaging-and-diffusion-tensor-imaging-in-patients-with-intracranial-masses
#18
Robert J Young, Ek T Tan, Kyung K Peck, Mehrnaz Jenabi, Sasan Karimi, Nicole Brennan, Jennifer Rubel, John Lyo, Weiji Shi, Zhigang Zhang, Marcel Prastawa, Xiaofeng Liu, Jonathan I Sperl, Robin Fatovic, Luca Marinelli, Andrei I Holodny
PURPOSE: To compare compressed diffusion spectrum imaging (CS-DSI) with diffusion tensor imaging (DTI) in patients with intracranial masses. We hypothesized that CS-DSI would provide superior visualization of the motor and language tracts. MATERIALS AND METHODS: We retrospectively analyzed 25 consecutive patients with intracranial masses who underwent DTI and CS-DSI for preoperative planning. Directionally-encoded anisotropy maps, and streamline hand corticospinal motor tracts and arcuate fasciculus language tracts were graded according to a 3-point scale...
October 11, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27721745/subcomponents-and-connectivity-of-the-inferior-fronto-occipital-fasciculus-revealed-by-diffusion-spectrum-imaging-fiber-tracking
#19
Yupeng Wu, Dandan Sun, Yong Wang, Yibao Wang
The definitive structure and functional role of the inferior fronto-occipital fasciculus (IFOF) are still controversial. In this study, we aimed to investigate the connectivity, asymmetry, and segmentation patterns of this bundle. High angular diffusion spectrum imaging (DSI) analysis was performed on 10 healthy adults and a 90-subject DSI template (NTU-90 Atlas). In addition, a new tractography approach based on the anatomic subregions and two regions of interest (ROI) was evaluated for the fiber reconstructions...
2016: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/27704641/parametrial-involvement-in-women-with-low-risk-early-stage-cervical-cancer
#20
A Vanichtantikul, P Tantbirojn, T Manchana
This study identified the incidence of parametrial involvement in low risk, early-stage cervical cancer patients and evaluated the factors associated with parametrial involvement. All stage IA2-IB1 cervical cancer patients who underwent radical hysterectomy with pelvic lymphadenectomy were retrospectively reviewed. Patients with squamous cell carcinoma or adenocarcinoma grade 1-2, tumour size less than 2 cm, no lymphovascular space invasion (LVSI), negative pelvic nodes and depth of stromal invasion (DSI) less than 10 mm were identified as the low-risk group...
October 5, 2016: European Journal of Cancer Care
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