keyword
https://read.qxmd.com/read/38608629/rapid-screening-of-infertility-associated-gynecological-conditions-via-ambient-glow-discharge-mass-spectrometry-utilizing-urine-metabolic-fingerprints
#1
JOURNAL ARTICLE
Yijiao Qu, Ming Chen, Yiran Wang, Liangliang Qu, Ruiyue Wang, Huihui Liu, Liping Wang, Zongxiu Nie
Infertility presents a widespread challenge for many families worldwide, often arising from various gynecological diseases (GDs) that hinder successful pregnancies. Current diagnostic methods for GDs have disadvantages such as low efficiency, high cost, misdiagnose, invasive injury and etc. This paper introduces a rapid, non-invasive, efficient, and straightforward analytical method that utilizes desorption, separation, and ionization mass spectrometry (DSI-MS) platform in conjunction with machine learning (ML) to detect urine metabolite fingerprints in patients with different GDs...
April 8, 2024: Talanta
https://read.qxmd.com/read/38584942/distinct-differences-of-vertical-phytoplankton-community-structure-in-mainstream-and-a-tributary-bay-of-the-three-gorges-reservoir-china
#2
JOURNAL ARTICLE
Lan Wang, Lu Tan, Qinghua Cai
The vertical distribution of phytoplankton plays a crucial role in shaping the dynamics and structure of aquatic communities. In highly dynamic reservoir systems, water level fluctuations significantly affect the physiochemical conditions and the phytoplankton community. However, the specific effects on the vertical characteristics of phytoplankton between the mainstream and the tributary bay of the reservoir remain unstudied. This study investigated the vertical aspects of phytoplankton density, biomass, α and β diversity through monthly sampling over two years in the mainstream (Chang Jiang, CJ) and a tributary bay (Xiang Xi, XX) of the Three Gorges Reservoir in China...
2024: Frontiers in Plant Science
https://read.qxmd.com/read/38584029/experiences-of-patients-with-unilateral-vocal-fold-paralysis-a-mixed-methods-study-of-the-insider-s-perspective
#3
JOURNAL ARTICLE
Imke Kissel, Iris Meerschman, Peter Tomassen, Evelien D'haeseleer, Kristiane Van Lierde
OBJECTIVE: Unilateral vocal fold paralysis (UVFP) is often characterized by severe dysphonia and has a significant impact on a patient's communication in daily and vocational situations. Having a better understanding of how UVFP influences quality of life and patient experiences can help improve patient-centered care in this population. Therefore, the purpose of this study was to explore the lived experiences of patients with UVFP. METHODS: Twenty-five adults with UVFP (age range: 39-84years) participated in the study...
April 6, 2024: Journal of Voice
https://read.qxmd.com/read/38579447/impact-of-typhoons-on-anthropogenic-nitrogen-sources-in-lake-sihwa-south-korea
#4
JOURNAL ARTICLE
Seung-Hee Kim, Min-Seob Kim, Dong-Hun Lee, Kyung-Hoon Shin
This study investigated the nitrate dual isotopic compositions (δ15 NNO3 and δ18 ONO3 ) of water samples to trace nitrate sources in Lake Sihwa, which encompasses various land-use types (e.g., urban, industry, wetland, and agriculture). The biogeochemical interactions of anthropogenic nitrogen sources (e.g., soil, road dust, and septic water) were also evaluated through multiple pathways from terrestrial boundaries to the water column. Based on increased concentrations of dissolved total nitrogen (DTN; 3...
April 3, 2024: Marine Pollution Bulletin
https://read.qxmd.com/read/38576769/randomized-controlled-trial-of-the-effect-of-an-exercise-rehabilitation-program-on-symptom-burden-in-maintenance-hemodialysis-a-clinical-research-protocol
#5
JOURNAL ARTICLE
Emilie Ford, Krista Stewart, Eric Garcia, Monica Sharma, Reid Whitlock, Ruth Getachew, Krista Rossum, Todd A Duhamel, Mauro Verrelli, James Zacharias, Paul Komenda, Navdeep Tangri, Claudio Rigatto, Jennifer M MacRae, Clara Bohm
BACKGROUND: People receiving hemodialysis experience high symptom burden that contributes to low functional status and poor health-related quality of life. Management of symptoms is a priority for individuals receiving hemodialysis but limited effective treatments exist. There is emerging evidence that exercise programming can improve several common dialysis-related symptoms. OBJECTIVE: The primary aim of this study is to evaluate the effect of an exercise rehabilitation program on symptom burden in individuals receiving maintenance hemodialysis...
2024: Canadian Journal of Kidney Health and Disease
https://read.qxmd.com/read/38575713/development-and-validation-of-a-questionnaire-for-assessing-visual-and-auditory-spatial-localization-abilities-in-dual-sensory-impairment
#6
JOURNAL ARTICLE
Yingzi Xiong, Joseph Paul Nemargut, Chris Bradley, Walter Wittich, Gordon E Legge
Spatial localization is important for social interaction and safe mobility, and relies heavily on vision and hearing. While people with vision or hearing impairment compensate with their intact sense, people with dual sensory impairment (DSI) may require rehabilitation strategies that take both impairments into account. There is currently no tool for assessing the joint effect of vision and hearing impairment on spatial localization in this large and increasing population. To this end, we developed a novel Dual Sensory Spatial Localization Questionnaire (DS-SLQ) that consists of 35 everyday spatial localization tasks...
April 4, 2024: Scientific Reports
https://read.qxmd.com/read/38566116/association-between-days-for-concussion-recovery-and-initial-specialty-clinic-evaluation-within-48%C3%A2-hours
#7
JOURNAL ARTICLE
Abel S Mathew, Todd Caze, August M Price, Desi Vasquez, John P Abt, Scott O Burkhart
BACKGROUND: Researchers have highlighted the importance of early access to concussion care within one week of injury in reducing recovery times. However, a persisting question for concussion researchers is "just how early is important?" The purpose of this study was to examine differences in recovery time as predicted by the number of days elapsed since injury (DSI) to initial evaluation among patients who had access to a specialty concussion clinic within seven days. We hypothesized that DSI group membership, even within seven days, would significantly predict risk of protracted recovery (i...
April 2, 2024: BMC Sports Science, Medicine and Rehabilitation
https://read.qxmd.com/read/38565736/a-new-clinical-model-for-predicting-lymph-node-metastasis-in-t1-colorectal-cancer
#8
RANDOMIZED CONTROLLED TRIAL
Kai Wang, Hui He, Yanyun Lin, Yanhong Zhang, Junguo Chen, Jiancong Hu, Xiaosheng He
PURPOSE: Lymph node metastasis (LNM) is a crucial factor that determines the prognosis of T1 colorectal cancer (CRC) patients. We aimed to develop a practical prediction model for LNM in T1 CRC. METHODS: We conducted a retrospective analysis of data from 825 patients with T1 CRC who underwent radical resection at a single center in China. All enrolled patients were randomly divided into a training set and a validation set at a ratio of 7:3 using R software. Risk factors for LNM were identified through multivariate logistic regression analyses...
April 3, 2024: International Journal of Colorectal Disease
https://read.qxmd.com/read/38558534/within-individual-reproducibility-of-a-dual-sample-oral-cholate-challenge-test-duo-and-simplified-versions-of-the-hepquant-shunt-test
#9
JOURNAL ARTICLE
Michael P McRae, John Kittelson, Steve M Helmke, Gregory T Everson
Current noninvasive liver tests measure fibrosis, inflammation, or steatosis and do not measure function. The HepQuant platform of noninvasive tests uniquely assesses both liver function and physiology through the hepatic uptake of stable isotopes of cholate. However, the prototypical HepQuant SHUNT test (SHUNT V1.0) is cumbersome to administer, requiring intravenous and oral administration of cholate and six peripheral venous blood samples over 90 min. To alleviate the burden of test administration, we explored whether an oral only (DuO) version, and other simplified versions, of the test could provide reproducible measurements of liver function...
April 2024: Clinical and Translational Science
https://read.qxmd.com/read/38556175/establishment-and-validation-of-a-2d-primary-gill-cell-culture-of-the-sevenband-grouper-hyporthodus-septemfasciatus
#10
JOURNAL ARTICLE
Rahul Rajendran, Rahul Krishnan, Myung-Joo Oh
A 2D primary gill cell culture system of the sevenband grouper (Hyporthodus septemfasciatus) was established to validate the pathogenesis of nervous necrosis virus (NNV) as observed in previous studies. This system, developed using the double-seeded insert (DSI) technique, yielded confluent cell layers. Upon challenge with NNV in a setup containing both autoclaved salt water and L15 media in the apical compartment, viral replication akin to that anticipated based on previous studies was observed. Consequently, we advocate for the utilization of primary gill cell culture as a viable alternative to conventional methodologies for investigating host pathogen interactions...
March 29, 2024: Journal of Virological Methods
https://read.qxmd.com/read/38555791/impaired-glymphatic-clearance-in-multiple-system-atrophy-a-diffusion-spectrum-imaging-study
#11
JOURNAL ARTICLE
Chuanying Shi, Guifang Guo, Weifei Wang, Haiyan Yu, Hua Fan, Peng Wu, Peiji Song, Dianrong Gong
INTRODUCTION: Impaired α-synuclein clearance is pivotal in the pathogenesis of neurodegenerative diseases. We evaluated glymphatic clearance in multiple system atrophy (MSA) patients using advanced imaging. METHODS: Forty-four MSA patients (11 with MSA-parkinsonian type [MSA-P] and 33 with MSA-cerebellar type [MSA-C]) and 30 healthy controls were studied using diffusion spectrum magnetic resonance imaging (DSI-MRI). Diffusivities were measured along the x-, y-, and z-axes to calculate the Analysis Along the Perivascular Space (ALPS) index...
March 29, 2024: Parkinsonism & related Disorders
https://read.qxmd.com/read/38545363/the-effectiveness-of-the-flip-technique-in-vertical-ductal-stenting
#12
JOURNAL ARTICLE
Bedri Aldudak, Süleyman Geter, Mehmet Murat
BACKGROUND: In this study, the flip technique was compared with the classical method in terms of procedural success and procedure time during ductal stent implantation (DSI) via the carotid artery in patients whose pulmonary blood flow is dependent on the vertical type of ductus arteriosus (DA). METHODS: Between January 2019 and June 2023, 40 patients (24 males, 16 females; mean age: 15.9±15.4 days; range, 1 to 68 days) with vertical ductus-dependent pulmonary circulation who underwent patent DA stent implantation via the carotid artery were included in the study...
January 2024: Türk Göğüs Kalp Damar Cerrahisi Dergisi
https://read.qxmd.com/read/38539603/qualitative-and-visual-along-tract-analysis-of-diffusion-based-parameters-in-patients-with-diffuse-gliomas
#13
JOURNAL ARTICLE
Markus Fahlström, Sadia Mirza, Åsa Alberius Munkhammar, Maria Zetterling, Francesco Latini
BACKGROUND: Grade 2-3 diffuse gliomas (DGs) show extensive infiltration through white matter (WM) tracts. Along-tract analysis of WM tracts based on diffusion tensor tractography (DTI) can been performed to assess the microstructural integrity of WM tracts. The clinical implication of these DTI-related findings is still under debate, especially in tumor patients. The aim of this study was to analyze and compare diffusion-based parameters along WM tracts and variables specific to WM -tumor interactions in DGs and correlate them with preoperative neuropsychological assessment...
February 26, 2024: Brain Sciences
https://read.qxmd.com/read/38539094/associations-between-cooking-fuel-use-its-transitions-and-worsening-sensory-impairments-among-chinese-middle-aged-and-older-adults-a-cohort-study
#14
JOURNAL ARTICLE
Shaojie Li, Guanghui Cui, Mingzheng Hu, Yang Hu, Longbing Ren, Yuling Jiang, Jing Sun, Zhe Luan, Kejia Hu, Yunquan Zhang, Gang Sun, Yao Yao
BACKGROUND: This study aimed to explore the associations between household air pollution (HAP), measured by cooking fuel use, sensory impairments (SI), and their transitions in Chinese middle-aged and older adults. METHODS: Participants were recruited from the 2011 China Health and Retirement Longitudinal Study (CHARLS) and were subsequently followed up until 2018. Data on SI were collected by self-reported hearing and vision impairments, which were divided into three categories: non-SI, single SI (hearing or vision impairment), and dual SI (DSI)...
March 27, 2024: BMC Geriatrics
https://read.qxmd.com/read/38538402/voice-treatment-of-school-aged-children-with-vocal-nodules-with-abclove-rehabilitation
#15
JOURNAL ARTICLE
Yanrui Bian, Jingmiao Wang, Haizhong Zhang, Xiaoyan Yin, Yubo Zhang
BACKGROUND: This study was to explore the effectiveness of the ABCLOVE exercise on school-aged children with vocal nodules after the treatment of budesonide. METHODS: Eighty-six school-aged children with vocal nodules were divided into control and ABCLOVE therapy groups. Subjective voice assessment and dysphonia severity index (DSI) assessment were performed before and after the 3-month of therapy. RESULTS: A significant improvement was observed in the ABCLOVE therapy group as compared with the control group (p = 0...
March 24, 2024: Pediatrics and Neonatology
https://read.qxmd.com/read/38523151/adequate-iodine-nutrition-and-higher-salt-intake-in-chinese-adults-aged-18-59-years-recommended-by-international-organizations
#16
JOURNAL ARTICLE
Diqun Chen, Ying Ye, Ying Lan, Meng He, Jiani Wu, Lijin Wang, Zhihui Chen
Iodine deficiency and excessive salt intake have adverse health effects. This study evaluated the iodine level and salt intake in Chinese adults aged 18-59 years after implementing the salt reduction program and compared with both the World Health Organization (WHO) and Chinese recommendations. Adults aged 18-59 years were randomly selected using multi-stage stratified random sampling in coastal urban area (CUA), non-coastal urban area (Non-CUA), coastal rural area (CRA), and non-coastal rural area (Non-CRA) of Fujian Province, China...
March 24, 2024: Scientific Reports
https://read.qxmd.com/read/38520359/a-practical-evaluation-of-measures-derived-from-compressed-sensing-diffusion-spectrum-imaging
#17
JOURNAL ARTICLE
Hamsanandini Radhakrishnan, Chenying Zhao, Valerie J Sydnor, Erica B Baller, Philip A Cook, Damien A Fair, Barry Giesbrecht, Bart Larsen, Kristin Murtha, David R Roalf, Sage Rush-Goebel, Russell T Shinohara, Haochang Shou, M Dylan Tisdall, Jean M Vettel, Scott T Grafton, Matthew Cieslak, Theodore D Satterthwaite
Diffusion Spectrum Imaging (DSI) using dense Cartesian sampling of q-space has been shown to provide important advantages for modeling complex white matter architecture. However, its adoption has been limited by the lengthy acquisition time required. Sparser sampling of q-space combined with compressed sensing (CS) reconstruction techniques has been proposed as a way to reduce the scan time of DSI acquisitions. However prior studies have mainly evaluated CS-DSI in post-mortem or non-human data. At present, the capacity for CS-DSI to provide accurate and reliable measures of white matter anatomy and microstructure in the living human brain remains unclear...
April 2024: Human Brain Mapping
https://read.qxmd.com/read/38511614/enhancing-tomato-disease-resistance-through-endogenous-antifungal-proteins-and-introduced-nematode-targeting-dsrna-of-biocontrol-agent-bacillus-velezensis-hs-3
#18
JOURNAL ARTICLE
Juan Han, Jinchi Zhu, Shuyuan Liu, Xuehan Sun, Shunchang Wang, Guopeng Miao
BACKGROUND: As a type of biological control agents (BCAs), Bacillus velezensis possesses the efficacy of inhibiting pathogenic microorganisms, promoting plant growth, and overcoming continuous cropping obstacles (CCOs). However, there is limited reporting on the optimization of the cultivation conditions for such biocontrol agents and their role as dsRNA delivery vectors. RESULTS: In this study, a B. velezensis strain HS-3 was isolated from the root zone of tomato plants with in vitro anti-Botrytis cinerea activity...
March 21, 2024: Pest Management Science
https://read.qxmd.com/read/38506649/strategies-used-during-the-cognitive-evaluation-of-older-adults-with-dual-sensory-impairment-a-scoping-review
#19
REVIEW
Shirley Dumassais, Margaret Kathleen Pichora-Fuller, Dawn Guthrie, Natalie A Phillips, Marie Savundranayagam, Walter Wittich
BACKGROUND: Dual sensory impairment (DSI), the combination of visual and hearing impairments, is associated with increased risk for age-related cognitive decline and dementia. Administering cognitive tests to individuals with sensory impairment is challenging because most cognitive measures require sufficient hearing and vision. Considering sensory limitations during cognitive test administration is necessary so that the effects of sensory and cognitive abilities on test performance can be differentiated and the validity of test results optimized...
March 1, 2024: Age and Ageing
https://read.qxmd.com/read/38504119/exploring-the-personality-and-relationship-factors-that-mediate-the-connection-between-differentiation-of-self-and-phubbing
#20
JOURNAL ARTICLE
Ora Peleg, Meyran Boniel-Nissim
One of the family patterns crucial for mental and physical well-being is differentiation of self. In this study, our aim was to investigate its impact on the phenomenon of phubbing-where individuals prioritize smartphones over in-person interactions. The prevalence of phubbing behavior has risen substantially in tandem with the increased adoption of smartphones. The study investigated familial, interpersonal, and personal factors that could potentially contribute to the escalation of phubbing behaviors. It was hypothesized that differentiation of self would be associated with phubbing through the mediation of fear of missing out, romantic relationship satisfaction, and loneliness in intimate relationships...
March 19, 2024: Scientific Reports
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