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https://www.readbyqxmd.com/read/30513768/acute-endothelial-benefits-of-fat-restriction-over-carbohydrate-restriction-in-type-2-diabetes-mellitus-beyond-carbs-and-fats
#1
Renate Luzía Barbosa-Yañez, Ulrike Dambeck, Linna Li, Jürgen Machann, Stefan Kabisch, Andreas F H Pfeiffer
BACKGROUND: Cardiovascular diseases (CVD) are the major cause of mortality in type 2 diabetes patients (T2DM). The causes are embedded in a complex interplay between excess body fat, insulin resistance and serum lipid anomalies. Endothelial homeostasis is strongly affected by this pathogenic network. Even though metabolic changes and weight loss improve vascular endothelial function, the effect of different dietary approaches is still uncertain for type 2 diabetes patients. OBJECTIVE: We aimed to compare the acute effects of a hypocaloric very low carbohydrate (VLC) diet versus a hypocaloric low fat (LF) diet on flow mediated dilation (FMD), intrahepatic lipid (IHL) accumulation and visceral adipose tissue as independent risk factors of CVD in T2DM patients...
December 1, 2018: Nutrients
https://www.readbyqxmd.com/read/30373291/guiding-ketogenic-diet-with-breath-acetone-sensors
#2
Andreas T Güntner, Julia F Kompalla, Henning Landis, S Jonathan Theodore, Bettina Geidl, Noriane A Sievi, Malcolm Kohler, Sotiris E Pratsinis, Philipp A Gerber
Ketogenic diet (KD; high fat, low carb) is a standard treatment for obesity, neurological diseases (e.g., refractory epilepsy) and a promising method for athletes to improve their endurance performance. Therein, the level of ketosis must be regulated tightly to ensure an effective therapy. Here, we introduce a compact and inexpensive breath sensor to monitor ketosis online and non-invasively. The sensor consists of Si-doped WO₃ nanoparticles that detect breath acetone selectively with non-linear response characteristics in the relevant range of 1 to 66 ppm, as identified by mass spectrometry...
October 28, 2018: Sensors
https://www.readbyqxmd.com/read/30291081/outcomes-of-a-digitally-delivered-low-carbohydrate-type-2-diabetes-self-management-program-1-year-results-of-a-single-arm-longitudinal-study
#3
Laura R Saslow, Charlotte Summers, James E Aikens, David J Unwin
BACKGROUND: Type 2 diabetes mellitus has serious health consequences, including blindness, amputation, stroke, and dementia, and its annual global costs are more than US $800 billion. Although typically considered a progressive, nonreversible disease, some researchers and clinicians now argue that type 2 diabetes may be effectively treated with a carbohydrate-reduced diet. OBJECTIVE: Our objective was to evaluate the 1-year outcomes of the digitally delivered Low-Carb Program, a nutritionally focused, 10-session educational intervention for glycemic control and weight loss for adults with type 2 diabetes...
August 3, 2018: JMIR diabetes
https://www.readbyqxmd.com/read/30172260/engineering-the-oleaginous-yeast-yarrowia-lipolytica-to-produce-the-aroma-compound-%C3%AE-ionone
#4
Jeffrey J Czajka, Justin A Nathenson, Veronica T Benites, Edward E K Baidoo, Qianshun Cheng, Yechun Wang, Yinjie J Tang
BACKGROUND: β-Ionone is a fragrant terpenoid that generates a pleasant floral scent and is used in diverse applications as a cosmetic and flavoring ingredient. A growing consumer desire for natural products has increased the market demand for natural β-ionone. To date, chemical extraction from plants remains the main approach for commercial natural β-ionone production. Unfortunately, changing climate and geopolitical issues can cause instability in the β-ionone supply chain. Microbial fermentation using generally recognized as safe (GRAS) yeast offers an alternative method for producing natural β-ionone...
September 1, 2018: Microbial Cell Factories
https://www.readbyqxmd.com/read/30116319/gsh-levels-affect-weight-loss-in-individuals-with-metabolic-syndrome-and-obesity-following-dietary-therapy
#5
Nikolaos Goutzourelas, Marina Orfanou, Ioannis Charizanis, George Leon, Demetrios A Spandidos, Demetrios Kouretas
This study examined the effects of redox status markers on metabolic syndrome (MetS) and obesity before and after dietary intervention and exercise for weight loss. A total of 103 adults suffering from MetS and obesity participated in this study and followed a personalized diet plan for 6 months. Body weight, body fat (BF) percentage (BF%), respiratory quotient (RQ) and the redox status markers, reduced glutathione (GSH), thiobarbituric acid reactive substances (TBARS) and protein carbonyls (CARB), were measured twice in each individual, before and after intervention...
August 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/30075165/ketogenic-diet-as-a-metabolic-therapy-for-mood-disorders-evidence-and-developments
#6
REVIEW
Elisa Brietzke, Rodrigo B Mansur, Mehala Subramaniapillai, Vicent Balanzá-Martínez, Maj Vinberg, Ana González-Pinto, Joshua D Rosenblat, Roger Ho, Roger S McIntyre
Despite significant advances in pharmacological and non-pharmacological treatments, mood disorders remain a significant source of mental capital loss, with high rates of treatment resistance, requiring a coordinated effort in investigation and development of efficient, tolerable and accessible novel interventions. Ketogenic diet (KD) is a low-carb diet that substantially changes the energetic matrix of the body including the brain. It has been established as an effective anticonvulsant treatment, and more recently, the role of KD for mental disorders has been explored...
November 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/30065408/sugar-specific-carbon-isotope-ratio-analysis-of-coconut-waters-for-authentication-purposes
#7
David Psomiadis, Nikoleta Zisi, Claudia Koger, Balazs Horvath, Bernd Bodiselitsch
The application of sugar-specific carbon isotope analysis by combining high performance liquid chromatography and isotope ratio mass spectrometry is described, for investigating the detection of added C4-plant sugars in coconut waters. Authenticity of coconut waters gains more importance since the product is considered a juice by the European Fruit Juice Association (AIJN), while it holds an increasing consumer preference as healthy, low-carb beverage. The detection potential was compared with the conventional total sugar carbon isotope analysis and it is demonstrated that the isotopic profile of individual sugars substantially improves the limit of detection of added C4-plant sugars in coconut water...
August 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/30047223/closed-loop-driven-by-control-to-range-algorithm-outperforms-threshold-low-glucose-suspend-insulin-delivery-on-glucose-control-albeit-not-on-nocturnal-hypoglycaemia-in-prepubertal-patients-with-type-1-diabetes-in-a-supervised-hotel-setting
#8
Eric Renard, Nadia Tubiana-Rufi, Elisabeth Bonnemaison-Gilbert, Régis Coutant, Fabienne Dalla-Vale, Anne Farret, Amélie Poidvin, Natacha Bouhours-Nouet, Charlotte Abettan, Caroline Storey-London, Aurelie Donzeau, Jerome Place, Marc D Breton
This randomized control trial investigated glucose control with closed-loop (CL) versus threshold-low-glucose-suspend (TLGS) insulin pump delivery in pre-pubertal children with type 1 diabetes in supervised hotel conditions. The patients [n = 24, age range: 7-12, HbA1c: 7.5 ± 0.5% (58 ± 5 mmol/mol)] and their parents were admitted twice at a 3-week interval. CL control to range or TLGS set at 3.9 mmoL/L were assessed for 48 hour in randomized order. Admissions included three meals and one snack, and physical exercise...
July 25, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29969145/-life-threatening-ketoacidosis-in-patients-with-type-2-diabetes-on-lchf-diet
#9
Kamila Bonikowska, Peter Magnusson, Åke Sjöholm
Patients with type 2 diabetes may develop severe ketoacidosis. A low carb high fat (LCHF) diet is oftentimes used by these patients for weight loss purposes but is also ketogenic. Antidiabetic SGLT2 inhibitors may increase glucagon secretion and may predispose to ketoacidosis, which is normoglycemic and thus makes it more difficult to suspect. We present two cases of severe ketoacidosis in type 2 diabetes patients on LCHF diet, one of which was also on SGLT2 inhibitor therapy.
June 29, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29955724/web-based-recruitment-and-survey-methodology-to-maximize-response-rates-from-followers-of-popular-diets-the-adhering-to-dietary-approaches-for-personal-taste-adapt-feasibility-survey
#10
Micaela C Karlsen, Alice H Lichtenstein, Christina D Economos, Sara C Folta, Gail Rogers, Paul F Jacques, Kara A Livingston, Katherine M Rancaño, Nicola M McKeown
Background: Although there is interest in popular diets such as vegan and vegetarian, Paleo, and other "whole food" diets, existing cohort studies lack data for these subgroups. The use of electronic data capture and Web-based surveys in nutrition research may be valuable for future studies by allowing targeting of specific dietary subgroups. Objective: The aim was to perform a Feasibility Survey (FS) to assess the practicality of Web-based research methods to gather data and to maximize response rates among followers of popular diets...
May 2018: Current developments in nutrition
https://www.readbyqxmd.com/read/29949894/dietary-patterns-in-secondary-prevention-of-heart-failure-a-systematic-review
#11
REVIEW
Gabriela Dos Reis Padilha, Karina Sanches Machado d'Almeida, Stefanny Ronchi Spillere, Gabriela Corrêa Souza
BACKGROUND: Diet is an important factor in secondary prevention of heart failure (HF) but there is still no consensus as to which dietary model should be adopted by this population. This systematic review aims to clarify the relationship between dietary patterns and secondary prevention in HF. METHODS: We searched the Medline, Embase and Cochrane databases for studies with different dietary patterns and outcomes of secondary prevention in HF. No limitation was used in the search...
June 26, 2018: Nutrients
https://www.readbyqxmd.com/read/29735572/how-low-can-you-go-does-lower-carb-translate-to-lower-glucose
#12
Carly Runge, Joyce M Lee
No abstract text is available yet for this article.
June 2018: Pediatrics
https://www.readbyqxmd.com/read/29541907/overweight-and-diabetes-prevention-is-a-low-carbohydrate-high-fat-diet-recommendable
#13
REVIEW
Fred Brouns
In the past, different types of diet with a generally low-carbohydrate content (< 50-< 20 g/day) have been promoted, for weight loss and diabetes, and the effectiveness of a very low dietary carbohydrate content has always been a matter of debate. A significant reduction in the amount of carbohydrates in the diet is usually accompanied by an increase in the amount of fat and to a lesser extent, also protein. Accordingly, using the term "low carb-high fat" (LCHF) diet is most appropriate...
June 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29535083/low-calorie-and-low-carb-diets-for-weight-loss-in-primary-care
#14
Jane Feinmann
No abstract text is available yet for this article.
March 13, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29446894/the-low-carb-craze
#15
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Diabetes Forecast
https://www.readbyqxmd.com/read/29385034/liver-fat-scores-moderately-reflect-interventional-changes-in-liver-fat-content-by-a-low-fat-diet-but-not-by-a-low-carb-diet
#16
RANDOMIZED CONTROLLED TRIAL
Stefan Kabisch, Sabrina Bäther, Ulrike Dambeck, Margrit Kemper, Christiana Gerbracht, Caroline Honsek, Anna Sachno, Andreas F H Pfeiffer
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disorder all over the world, mainly being associated with a sedentary lifestyle, adiposity, and nutrient imbalance. The increasing prevalence of NAFLD accommodates similar developments for type 2 diabetes and diabetes-related comorbidities and complications. Therefore, early detection of NAFLD is an utmost necessity. Potentially helpful tools for the prediction of NAFLD are liver fat indices. The fatty liver index (FLI) and the NAFLD-liver fat score (NAFLD-LFS) have been recently introduced for this aim...
January 31, 2018: Nutrients
https://www.readbyqxmd.com/read/29368448/low-carbohydrate-diets-may-increase-risk-of-neural-tube-defects
#17
Tania A Desrosiers, Anna Maria Siega-Riz, Bridget S Mosley, Robert E Meyer
BACKGROUND: Folic acid fortification significantly reduced the prevalence of neural tube defects (NTDs) in the United States. The popularity of "low carb" diets raises concern that women who intentionally avoid carbohydrates, thereby consuming fewer fortified foods, may not have adequate dietary intake of folic acid. METHODS: To assess the association between carbohydrate intake and NTDs, we analyzed data from the National Birth Defects Prevention Study from 1,740 mothers of infants, stillbirths, and terminations with anencephaly or spina bifida (cases), and 9,545 mothers of live born infants without a birth defect (controls) conceived between 1998 and 2011...
July 3, 2018: Birth Defects Research
https://www.readbyqxmd.com/read/29351387/letter-to-the-editor-low-carb-meal-plan-and-postmeal-exercise
#18
Elsamma Chacko
No abstract text is available yet for this article.
December 1, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29320401/mediterranean-diet-and-other-dietary-patterns-in-primary-prevention-of-heart-failure-and-changes-in-cardiac-function-markers-a-systematic-review
#19
REVIEW
Karina Sanches Machado d'Almeida, Stefanny Ronchi Spillere, Priccila Zuchinali, Gabriela Corrêa Souza
BACKGROUND: Heart failure (HF) is a complex syndrome and is recognized as the ultimate pathway of cardiovascular disease (CVD). Studies using nutritional strategies based on dietary patterns have proved to be effective for the prevention and treatment of CVD. Although there are studies that support the protective effect of these diets, their effects on the prevention of HF are not clear yet. METHODS: We searched the Medline, Embase, and Cochrane databases for studies that examined dietary patterns, such as dietary approaches to stop hypertension (DASH diet), paleolithic, vegetarian, low-carb and low-fat diets and prevention of HF...
January 10, 2018: Nutrients
https://www.readbyqxmd.com/read/29317639/tectonically-triggered-sediment-and-carbon-export-to-the-hadal-zone
#20
Rui Bao, Michael Strasser, Ann P McNichol, Negar Haghipour, Cameron McIntyre, Gerold Wefer, Timothy I Eglinton
Sediments in deep ocean trenches may contain crucial information on past earthquake history and constitute important sites of carbon burial. Here we present 14 C data on bulk organic carbon (OC) and its thermal decomposition fractions produced by ramped pyrolysis/oxidation for a core retrieved from the >7.5 km-deep Japan Trench. High-resolution 14 C measurements, coupled with distinctive thermogram characteristics of OC, reveal hemipelagic sedimentation interrupted by episodic deposition of pre-aged OC in the trench...
January 9, 2018: Nature Communications
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