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COMPARATIVE STUDY
Douglas Fredericks, Emily B Petersen, Nicole Watson, Nicole Grosland, Katherine Gibson-Corley, Joseph Smucker
BACKGROUND: The drawbacks of iliac crest autograft as graft material for spine fusion are well reported. Despite continued modifications to improve bone healing capacity, the efficacy of synthetic graft materials as stand-alone replacements remains uncertain. The rabbit posterolateral fusion model is an established environment for testing of fusion concepts. It offers the opportunity to obtain radiographic, biomechanical and histological data on novel fusion materials. The objective of this study was to compare the spine fusion capability of two synthetic bone graft products in an established rabbit posterolateral spine fusion (PLF) model: Signafuse® Bioactive Bone Graft Putty and Actifuse® ABX...
2016: Iowa Orthopaedic Journal
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