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Bipolar type 2

Hehe Zhang, Sijung Yoo, Stephan Menzel, Carsten Funck, Felix Cüppers, Dirk J Wouters, Cheol Seong Hwang, Rainer Waser, Susanne Hoffmann-Eifert
Redox-type resistive random access memories (ReRAM) based on transition metal oxides are studied as adjustable two-terminal devices for integrated network applications beyond von Neumann computing. The prevailing, so-called, counter-eight-wise (c8w) polarity of the switching hysteresis in filamentary-type valence change mechanism (VCM) devices originates from a temperature and field controlled drift-diffusion process of mobile ions, predominantly oxygen vacancies in the switching oxide. Recently, a bipolar resistive switching (BRS) process with opposite polarity, so-called, eight-wise (8w) switching has been reported that, especially for TiO2 cells, is still not completely understood...
August 8, 2018: ACS Applied Materials & Interfaces
Niloy Ghosh, Jeremiah H Moon, Jonathan A Henderson, Robert P Kauffman
An 18-year-old virginal woman was referred to the reproductive endocrinology clinic with primary amenorrhoea and secondary sexual development in the absence of pelvic pain. Additionally, she had significant congenital sensorineural hearing loss, autism, bipolar disorder and class III obesity. On physical examination, secondary sexual development was confirmed (Tanner 5 breasts and Tanner 4 pubic hair). She refused further pelvic examination following prior attempts by the referring physicians. Serum leutinizing hormone (LH), follicle sitmulating hormone (FSH)...
July 30, 2018: BMJ Case Reports
Dmitry Filatov, Inga Kazantseva, Dmitry Antonov, Ivan Antonov, Maria Shenina, Dmitry Pavlov, Oleg Gorshkov
We report on the investigation of the resistive switching (RS) in the ultrathin (≈5 nm in thickness) yttria-stabilized zirconia (YSZ) films with single layers of Au nanoparticles (NPs) by conductive atomic force microscopy (CAFM). Besides the butterfly-type hysteresis loops in the current-voltage ( I - V ) curves of the contact of the CAFM probe to the investigated film surface corresponding to the bipolar RS, the negative differential resistance (NDR) has been observed in the I - V curves of the AFM probe contact to the YSZ films with Au NPs in the conductive ("ON") state...
2018: Scanning
Emmanuelle Bostock, Kenneth Kirkby, Michael Garry, Bruce Taylor, Jason A Hawrelak
Background: DSM-5 introduced the diagnostic category of substance/medication-induced bipolar and related disorder. This systematic review examines published reports linking mania with the consumption of herbal medicines (HM), excluding cannabis. Putative pathophysiological mechanisms that may account for the reported HM being associated with mania are discussed. Methods: A systematic search of EMBASE, CINAHL, Health Source, PsychINFO, and PubMed. The quality of case reports meeting inclusion criteria was assessed using the modified Quality Assessment Scale by Agbabiaka...
2018: Frontiers in Psychiatry
David A Kahn
In this issue of the journal, 2 case reports are presented that illustrate explicit influences of structural brain lesions on psychiatric symptoms. In both cases, the patients had preexisting, classically diagnosed psychiatric disorders-schizophrenia in the first case and bipolar I disorder in the second case. In the first case, a 61-year-old woman with chronic paranoid schizophrenia experienced a marked reduction in psychotic symptoms after bilateral frontal strokes. In the second case, a 60-year-old man who had experienced manic and depressive episodes since his 20s developed partial complex seizures after having repeated head trauma in his 40s, with subsequent onset of chronic personality changes associated with temporal lobe epilepsy that made his psychiatric treatment a greater challenge...
May 2018: Journal of Psychiatric Practice
Carina Kelbsch, Archana Jalligampala, Torsten Strasser, Paul Richter, Katarina Stingl, Christoph Braun, Daniel L Rathbun, Eberhart Zrenner, Helmut Wilhelm, Barbara Wilhelm, Tobias Peters, Krunoslav Stingl
The purpose was to evaluate retinal function by measuring pupillary responses to sinusoidal transcorneal electrostimulation in healthy young human subjects. This work also translates data from analogous in vitro experiments and connects it to the pupillary responses obtained in human experiments. 14 healthy human subjects participated (4 males, 10 females); for the in vitro experiments, two male healthy mouse retinas (adult wild-type C57B/6J) were used. Pupillary responses to sinusoidal transcorneal electrostimulation of varying stimulus carrier frequencies (10, 20 Hz; envelope frequency constantly kept at 1...
July 10, 2018: Experimental Eye Research
V Lequimener-de Lorgeril, M Chirio-Espitalier, M Grall-Bronnec
INTRODUCTION: Bipolar disorder is a mental illness that is associated with a long-term impairment in psychosocial functioning and quality of life. The objective of this study was to evaluate the influence of a therapeutic education program on the quality of life of patients with bipolar disorder (type 1 or 2). METHOD: This study included 18 patients with bipolar disorder (type 1 or 2) following the therapeutic education program on bipolar disorder which includes 8 sessions of 2hours each...
July 5, 2018: L'Encéphale
Van Quang Nguyen, Thi Huong Nguyen, Van Thiet Duong, Ji Eun Lee, Su-Dong Park, Jae Yong Song, Hyun-Min Park, Anh Tuan Duong, Sunglae Cho
ᅟ: We report on the successful preparation of Bi-doped n-type polycrystalline SnSe by hot-press method. We observed anisotropic transport properties due to the (h00) preferred orientation of grains along the pressing direction. The electrical conductivity perpendicular to the pressing direction is higher than that parallel to the pressing direction, 12.85 and 6.46 S cm-1 at 773 K for SnSe:Bi 8% sample, respectively, while thermal conductivity perpendicular to the pressing direction is higher than that parallel to the pressing direction, 0...
July 6, 2018: Nanoscale Research Letters
Jérémy Lambert, Michael Chekroun, Hélène Gilet, Catherine Acquadro, Benoit Arnould
BACKGROUND: Patients with chronic conditions are required to take long-term treatments for their disease itself or to prevent any potential health risks. Measuring patient acceptance of their medication should help to better understand and predict patients' behavior toward treatment. This study aimed to describe the level of patient acceptance toward various long-term treatments in real life using an online patient community. METHODS: This was an observational, cross-sectional study conducted through the French Carenity platform...
July 6, 2018: Health and Quality of Life Outcomes
Antonio L Teixeira, Clarissa S Gama, Natalia P Rocha, Mauro M Teixeira
Eotaxin-1/CCL11 is a chemokine originally implicated in the selective recruitment of eosinophils into inflammatory sites during allergic reactions, being thoroughly investigated in asthma, allergic rhinitis, and other eosinophil-related conditions. Eotaxin-1/CCL11 is also involved with a skewed immune response toward a type-2 (Th2) profile. In addition to its role in immune response, recent studies have shown that eotaxin-1/CCL11 is associated with aging, neurogenesis and neurodegeneration, being able to influence neural progenitor cells, and microglia...
2018: Frontiers in Psychiatry
Rebecca H Campbell, Michael Diduch, Kristen N Gardner, Christopher Thomas
Schizophrenia and bipolar disorder are severe and debilitating psychiatric disorders. Despite the availability of numerous antipsychotic drugs, many patients still experience poor outcomes and treatment-limiting adverse side effects. Cariprazine is a novel antipsychotic with unique pharmacodynamic and pharmacokinetic properties. It is both a dopamine type 2 and dopamine type 3 partial agonist with 2 equipotent metabolites, desmethyl cariprazine and didesmethyl cariprazine, of which didesmethyl cariprazine has a half-life of 1 to 3 weeks...
September 2017: The mental health clinician
Lisa Masucci, Aysegul Erman, Murray D Krahn, Dean Elterman
INTRODUCTION: Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland, which results in the development of lower urinary tract symptoms that can interfere with a patient's daily activities and negatively impact their quality of life. The gold standard treatment for moderate to severe BPH has been transurethral resection of the prostate (TURP), however, this procedure is associated with prolonged hospitalizations and increased complications. An alternative to TURP is Greenlight photoselective vaporization of the prostate (PVP), which is associated with better perioperative safety...
June 19, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Jaclyn A Friedman, Jacqueline M K Wong, Angela Chaudhari, Susan Tsai, Magdy P Milad
PURPOSE OF REVIEW: Submucosal uterine leiomyomas are a common benign pelvic tumor that can cause abnormal uterine bleeding and may contribute to infertility and miscarriage. Hysteroscopic myomectomy is the treatment of choice to alleviate bleeding from these myomas and to normalize the uterine cavity. This review discusses the techniques and recent evidence for hysteroscopic myomectomy and examines the two primary surgical tools employed today: the bipolar resectoscope and hysteroscopic mechanical morcellator...
August 2018: Current Opinion in Obstetrics & Gynecology
Gul Karacetin, Ayse Rodopman Arman, Nese Perdahli Fis, Esra Demirci, Sevgi Ozmen, Selma Tural Hesapcioglu, Didem Oztop, Ali Evren Tufan, Umit Tural, Evrim Aktepe, Hatice Aksu, Ulku Akyol Ardic, Senem Basgul, Oznur Bilac, Murat Coskun, Gonca Gul Celik, Sevcan Karakoc Demirkaya, Onur Burak Dursun, Ibrahim Durukan, Tulin Fidan, Salih Gencoglan, Cem Gokcen, Emel Sari Gokten, Isık Gorker, Vahdet Gormez, Ozlem Yildiz Gundogdu, Cihat Kagan Gurkan, Sabri Herguner, Hasan Kandemir, Birim Gunay Kilic, Ayse Kilincaslan, Tuba Mutluer, Serhat Nasiroglu, Ozlem Ozel Ozcan, Mucahit Ozturk, Sermin Yalin Sapmaz, Serkan Suren, Nilfer Sahin, Aysegul Yolga Tahiroglu, Fevziye Toros, Fatih Unal, Pinar Vural, Ipek Percinel Yazici, Kemal Utku Yazici, Veli Yildirim, Yasemin Yulaf, Murat Yuce, Tugba Yuksel, Devrim Akdemir, Hatice Altun, Basak Ayik, Ayhan Bilgic, Ozlem Hekim Bozkurt, Emine Demirbas Cakir, Veysi Ceri, Nagehan Ucok Demir, Gulser Dinc, Mustafa Yasin Irmak, Dursun Karaman, Mehmet Fatih Kinik, Betul Mazlum, Nursu Cakin Memik, Dilsad Foto Ozdemir, Hayati Sinir, Bedia Ince Tasdelen, Beril Taskin, Cagatay Ugur, Pınar Uran, Taciser Uysal, Ozden Sukran Uneri, Savas Yilmaz, Sultan Seval Yilmaz, Burak Acikel, Huseyin Aktas, Rumeysa Alaca, Betul Gul Alic, Mahmoud Almbaidheen, Fatma Pinar Ari, Cihan Aslan, Ender Atabay, Merve Gunay Ay, Hilal Aydemir, Gülseda Ayranci, Zehra Babadagi, Hasan Bayar, Pelin Con Bayhan, Ozlem Bayram, Nese Dikmeer Bektas, Kivanc Kudret Berberoglu, Recep Bostan, Yasemin Cakan, Merve Arici Canli, Mehmet Akif Cansiz, Cansin Ceylan, Nese Coskun, Seyma Coskun, Ibrahim Demir, Nuran Demir, Esen Yildirim Demirdogen, Busra Dogan, Yunus Emre Donmez, Funda Donder, Aysegul Efe, Safak Eray, Seda Erbilgin, Semih Erden, Elif Gokce Ersoy, Tugba Eseroglu, Sumeyra Kina Firat, Ezgi Eynalli Gok, Seyda Celik Goksoy, Gulen Guler, Zafer Gules, Gulay Gunay, Serkan Gunes, Adem Gunes, Gokcen Guven, Havvana Horozcu, Ayse Irmak, Umit Isik, Ozlem Kahraman, Bilge Merve Kalayci, Umut Karaaslan, Mehmet Karadag, Hilal Tugba Kilic, Fethiye Kilicaslan, Duygu Kinay, Esra Bulanik Koc, Omer Kocael, Rahime Kadir Mutlu, Zejnep San, Kevser Nalbant, Nilufer Okumus, Fatih Ozbek, Fatma Akkus Ozdemir, Hanife Ozdemir, Borte Gurbuz Ozgur, Selcuk Ozkan, Esra Yildirim Ozyurt, Berna Polat, Hatice Polat, Ebru Sekmen, Mehmet Sertcelik, Feyza Hatice Sevgen, Oguz Sevince, Ulker Shamkhalova, Funda Suleyman, Nurcan Eren Simsek, Yasar Tanir, Mehmet Tekden, Seyhan Temtek, Melike Topal, Zehra Topal, Tugba Turk, Halit Necmi Ucar, Filiz Ucar, Duygu Uygun, Necati Uzun, Zeynep Vatansever, Neslihan Gokce Yazgili, Dilsad Miniksar Yildiz, Nazike Yildiz, Eyup Sabri Ercan
AIM: To determine the prevalence of affective disorders in Turkey among a representative sample of Turkish population. METHODS: This study was conducted as a part of the "The Epidemiology of Childhood Psychopathology in Turkey" (EPICPAT-T) Study, which was designed by the Turkish Association of Child and Adolescent Mental Health. The inclusion criterion was being a student between the second and fourth grades in the schools assigned as study centers. The assessment tools used were the K-SADS-PL, and a sociodemographic form that was designed by the authors...
May 30, 2018: Journal of Affective Disorders
M Valentin, L Radon, J Duclos, F Curt, N Godart
PURPOSE: Anorexia nervosa is often accompanied by comorbid mood disorders, in particular depression, but individual or family history of bipolar disorders has not frequently been explored in anorexia nervosa. The objectives of the present study were: (1) to assess the frequency of bipolar disorders in patients with anorexia nervosa hospitalized in adolescence and in their parents, (2) to determine whether the patients with a personal or family history of bipolar disorders present particular characteristics in the way in which anorexia nervosa manifests itself, in their medical history, in the secondary diagnoses established, and in the treatments prescribed...
June 20, 2018: L'Encéphale
Lee-Won Chong, Chih-Chao Hsu, Chang-Yin Lee, Ruey-Hwang Chou, Cheng-Li Lin, Kuang-Hsi Chang, Yi-Chao Hsu
BACKGROUND: Bipolar disorder (BD), a type of psychiatric mood disorder, is manifested by chronic and recurrent mood fluctuations. This study aims to determine whether hepatitis B virus (HBV) or hepatitis C virus (HCV) infection is a risk factor for BD. METHODS: A total of 48,215 patients with newly diagnosed viral hepatitis from 2000 to 2010 were identified and frequency-matched with 192,860 people without hepatitis. Both groups were followed until diagnosis with BD, withdrawal from the national health insurance program, or the end of 2011...
June 22, 2018: Journal of Translational Medicine
Torur Dalsgaard, Morten D Jensen, Dorthe Hartwell, Berit J Mosgaard, Annemette Jørgensen, Bente R Jensen
OBJECTIVE: To study musculoskeletal workload in experienced surgeons during laparoscopic surgery (LS) compared with robotic assisted laparoscopy (RALS). BACKGROUND: 70-90% of surgeons who regularly perform LS report musculoskeletal symptoms, mainly in neck and shoulders. Data regarding the potential ergonomic benefits of RALS in a clinical setting is very limited. METHODS: Twelve surgeons with advanced experience in both LS and RALS each performed 2 hysterectomies on the same day...
June 19, 2018: Annals of Surgery
Priyanka Bhatia, Ajeet Sidana, Subhash Das, Manoj Kumar Bajaj
Background: A substantial proportion of euthymic bipolar disorder patients have neuropsychological impairment which can have a significant impact on the overall functional recovery. Materials and Methods: A total of 60 bipolar disorder patients, currently in euthymic phase for the last 3 months with minimum duration of illness 2 years and current Young Mania Rating Scale <7 and Hamilton Depression Rating Scale <6, currently on medications were administrated various neuropsychological tests...
May 2018: Indian Journal of Psychological Medicine
Vasily Kerov, Joseph G Laird, Mei-Ling Joiner, Sharmon Knecht, Daniel Soh, Jussara Hagen, Sarah H Gardner, Wade Gutierrez, Takeshi Yoshimatsu, Sajag Bhattarai, Teresa Puthussery, Nikolai O Artemyev, Arlene V Drack, Rachel O Wong, Sheila A Baker, Amy Lee
α2 δ-4 is an auxiliary subunit of voltage-gated Cav 1.4 L-type channels that regulate the development and mature exocytotic function of the photoreceptor ribbon synapse. In humans, mutations in the CACNA2D4 gene encoding α2 δ-4 cause heterogeneous forms of vision impairment in humans, the underlying pathogenic mechanisms of which remain unclear. To investigate the retinal function of α2 δ-4, we used genome editing to generate an α2 δ-4 knock-out (α2 δ-4 KO) mouse. In male and female α2 δ-4 KO mice, rod spherules lack ribbons and other synaptic hallmarks early in development...
July 4, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Amy M Bauer, Sarah Hodsdon, Jared M Bechtel, John C Fortney
BACKGROUND: Despite a proliferation of patient-facing mobile apps for mental disorders, there is little literature guiding efforts to incorporate mobile tools into clinical care delivery and integrate patient-generated data into care processes for patients with complex psychiatric disorders. OBJECTIVE: The aim of this study was to seek to gain an understanding of how to incorporate a patient-provider mobile health (mHealth) platform to support the delivery of integrated primary care-based mental health services (Collaborative Care) to rural patients with posttraumatic stress disorder and/or bipolar disorder...
June 6, 2018: Journal of Medical Internet Research
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