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https://www.readbyqxmd.com/read/30336618/a-chemometrics-approach-comparing-volatile-changes-during-the-shelf-life-of-apple-juice-processed-by-pulsed-electric-fields-high-pressure-and-thermal-pasteurization
#1
Biniam Kebede, Pui Yee Lee, Sze Ying Leong, Vidya Kethireddy, Qianli Ma, Kemal Aganovic, Graham T Eyres, Nazimah Hamid, Indrawati Oey
High-Pressure Processing (HPP) and Pulsed Electric Fields (PEF) processing technologies are being used increasingly on a commercial basis, with high-quality labelled fruit juices being one of the most important promotion strategies. Quality-related enzymes, which might still be active after HPP and PEF pasteurization, can cause undesirable aroma changes during storage. This study investigated volatile changes during the shelf life of PEF (15.5 kV/cm and specific energy of 158 kJ/L), HPP (600 MPa for 3 min), and thermally (72 °C for 15 s) pasteurized Jazz apple juices-up to five weeks...
October 17, 2018: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/30327622/investigating-the-role-of-the-primary-motor-cortex-in-musical-creativity-a-transcranial-direct-current-stimulation-study
#2
Aydin Anic, Kirk N Olsen, William Forde Thompson
Neuroscientific research has revealed interconnected brain networks implicated in musical creativity, such as the executive control network, the default mode network, and premotor cortices. The present study employed brain stimulation to evaluate the role of the primary motor cortex (M1) in creative and technically fluent jazz piano improvisations. We implemented transcranial direct current stimulation (tDCS) to alter the neural activation patterns of the left hemispheric M1 whilst pianists performed improvisations with their right hand...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/30325089/a-novel-approach-to-avoid-baclofen-withdrawal-when-faced-with-infected-baclofen-pumps
#3
Roy S Hwang, Vishad Sukul, Claire Collison, Julia Prusik, Julie G Pilitsis
BACKGROUND: Intrathecal (IT) Baclofen is beneficial for spasticity, but if pumps become infected necessitating removal, baclofen withdrawal is difficult to manage and life-threatening. Furthermore there is no consistency between dosing and severity of withdrawal. Case reports detail full baclofen withdrawal at dosages of 260 μg/day. OBJECTIVE: To demonstrate that in patients on stable IT baclofen for prolonged periods, externalizing a patient's original IT pump is a safe, effective way to wean IT doses...
October 16, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30264870/early-us-experience-with-stimulation-of-the-dorsal-root-ganglia-for-the-treatment-of-peripheral-neuropathy-in-the-lower-extremities-a-multicenter-retrospective-case-series
#4
Steven Falowski, Jason E Pope, Adil Raza
BACKGROUND: Peripheral neuropathy is a chronic pain disorder involving physical, chemical, or metabolic damage to peripheral nerves. Its pain can be intense and disabling. Dorsal root ganglion (DRG) stimulation is an effective treatment for neuropathic pain, including cases with the limited regional distributions that often characterize peripheral neuropathy. METHODS: A retrospective analysis was completed. Patients were included on the basis of having chronic intractable peripheral neuropathy of the legs and/or feet and responding successfully to a trial of DRG stimulation with leads at L4-S1...
September 28, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30169321/treatment-of-paediatric-narcolepsy-with-sodium-oxybate-a-double-blind-placebo-controlled-randomised-withdrawal-multicentre-study-and-open-label-investigation
#5
Giuseppe Plazzi, Chad Ruoff, Michel Lecendreux, Yves Dauvilliers, Carol L Rosen, Jed Black, Rupa Parvataneni, Diane Guinta, Youyu Grace Wang, Emmanuel Mignot
BACKGROUND: Narcolepsy is a lifelong neurological disorder with onset commonly in childhood or adolescence. No drugs are indicated for cataplexy and excessive daytime sleepiness in paediatric patients with narcolepsy. Sodium oxybate is approved for use in adult patients with excessive daytime sleepiness or cataplexy, or both, in narcolepsy. We aimed to examine the safety and efficacy of sodium oxybate oral solution treatment in children and adolescents who have narcolepsy with cataplexy...
July 2018: Lancet Child & Adolescent Health
https://www.readbyqxmd.com/read/30134929/transnational-pharmacogovernance-emergent-patterns-in-the-jazz-of-pharmaceutical-policy-convergence
#6
Mary Wiktorowicz, Kathy Moscou, Joel Lexchin
BACKGROUND: As a transnational policy network, the International Council for Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) aligns international regulatory standards to address the pressures of globalization on the pharmaceutical industry and increase access to new medicines. Founding ICH members include regulators and pharmaceutical industry trade associations in the European Union, the United States and Japan. In this paper we explore the manner in which state interdependence fosters the conditions for regulatory harmonization by tracing the underlying parallels between ICH and member state pharmacogovernance to clarify emergent patterns in regulatory policy convergence...
August 22, 2018: Globalization and Health
https://www.readbyqxmd.com/read/30113235/scavenger-receptor-class-bi-sr-bi-mediates-uptake-of-cpx-351-into-k562-leukemia-cells
#7
Yunyun Di, Ellen K Wasan, Jacqueline Cawthray, Kishor M Wasan
PURPOSE: CPX-351 is a liposomal formulation of cytarabine and daunorubicin encapsulated at a 5:1 molar ratio, for the treatment of acute myeloid leukemia. The Scavenger Receptor class B type I (SR-BI) plays an important role in mediating the uptake of high-density lipoproteins. The purpose of this study is to assess the role of the cell surface lipoprotein receptor SR-BI in the uptake of CPX-351 liposomes (Jazz Pharmaceuticals) into K562 leukemia cells. METHODS: K562 cells were pre-treated with 10 nM siRNA for 48 h and then treated with varying amount of CPX-351 for 24, 48 and 72 h...
September 5, 2018: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/30010370/rapid-timing-of-musical-aesthetic-judgments
#8
Amy M Belfi, Anna Kasdan, Jess Rowland, Edward A Vessel, G Gabrielle Starr, David Poeppel
In recent years, psychological models of perception have undergone reevaluation due to a broadening of focus toward understanding not only how observers perceive stimuli but also how they subjectively evaluate stimuli. Here, we investigated the time course of such aesthetic evaluations using a gating paradigm. In a series of experiments, participants heard excerpts of classical, jazz, and electronica music. Excerpts were of different durations (250 ms, 500 ms, 750 ms, 1,000 ms, 2,000 ms, 10,000 ms) or note values (eighth note, quarter note, half note, dotted-half note, whole note, and entire 10,000 ms excerpt)...
July 16, 2018: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/30005061/species-in-ecosystems-and-all-that-jazz
#9
Oswald J Schmitz
Ecosystem ecologists explore how different kinds of species fit together to drive ecosystem processes such as nutrient cycling and productivity. This research is motivated by theories that assume that the suite of traits that characterize a species' form determines its function, that these traits have become fixed over evolutionary time, and that ensuing ecosystem process are not resilient to environmental change. Here, I explore new research that re-evaluates this theory. Recent results suggest that functional traits are malleable, enabling species to rapidly respond and adapt to each other as environmental conditions change with predictable effects on ecosystem processes...
July 2018: PLoS Biology
https://www.readbyqxmd.com/read/29952176/the-effect-of-jazz-dance-on-physical-and-mental-health-of-students-with-different-physical-fitness-a-randomized-controlled-trial
#10
Ziheng Wang, Guanghui An, Wanting Zhang, Guang Yang
BACKGROUND: The physical and mental health of college students tends to continuously decline worldwide. Thus, improving their health is necessary. Jazz dance may be one of the effective exercises to improve one's health. However, the effect of jazz dance exercise on different physical fitness level and whether the intensity of jazz dance exercises can improve physical and mental health simultaneously and efficiently need to be investigated. In this study, we systematically assessed the effect of jazz dance on physical and mental health of college students by a rigorous randomized, parallel-controlled design...
June 27, 2018: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29735764/autoregulation-of-the-s-mutans-slor-metalloregulator-is-constitutive-and-driven-by-an-independent-promoter
#11
Patrick Monette, Richard Brach, Annie Cowan, Roger Winters, Jazz Weisman, Foster Seybert, Kelsey Goguen, James Chen, Arthur Glasfeld, Grace Spatafora
Streptococcus mutans , one of ∼600 bacterial species in the human oral cavity, is among the most acidogenic constituents of the plaque biofilm. Considered to be the primary causative agent of dental caries, S. mutans harbors a 25kDa SloR metalloregulatory protein which controls metal ion transport across the bacterial cell membrane to maintain essential metal ion homeostasis. The expression of SloR derives, in part, from transcriptional readthrough of the sloABC operon which encodes a Mn2+ /Fe2+ ABC transport system...
May 7, 2018: Journal of Bacteriology
https://www.readbyqxmd.com/read/29691698/food-approach-conditioning-and-discrimination-learning-using-sound-cues-in-benthic-sharks
#12
Catarina Vila Pouca, Culum Brown
The marine environment is filled with biotic and abiotic sounds. Some of these sounds predict important events that influence fitness while others are unimportant. Individuals can learn specific sound cues and 'soundscapes' and use them for vital activities such as foraging, predator avoidance, communication and orientation. Most research with sounds in elasmobranchs has focused on hearing thresholds and attractiveness to sound sources, but very little is known about their abilities to learn about sounds, especially in benthic species...
July 2018: Animal Cognition
https://www.readbyqxmd.com/read/29688097/-doctor-jazz-lessons-that-medical-professionals-can-learn-from-jazz-musicians
#13
Allard E van Ark, Marjo Wijnen-Meijer
BACKGROUND: The worlds of a physician and a jazz musician seem entirely different. Various studies, however, relating the concepts behind jazz music to medical practice and education, have been published. The aim of this essayistic review is to summarize previously described concepts behind jazz music and its required artistic skills that could be translated to medicine, encouraging doctors, medical students and medical educators to see their professional environment from a different perspective...
April 24, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29599738/peer-learning-in-instrumental-practicing
#14
Siw G Nielsen, Guro G Johansen, Harald Jørgensen
In higher music education (HME), the notion of "private teaching, private learning" has a long tradition, where the learning part rests on the student's individual practicing between instrumental lessons. However, recent research suggests that collaborative learning among peers is beneficial in several aspects, such as sense of belonging, motivation and self-efficacy. This is consistent with the concept of vicarious learning. In this study, we conducted a survey among bachelor music students in church music, performance or music education programs enrolled in a music academy ( N = 96), where parts of the questionnaire addressed peer learning and peer's influence on the students's instrumental practicing, and the degree of satisfaction with their practicing...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29515867/shared-periodic-performer-movements-coordinate-interactions-in-duo-improvisations
#15
Tuomas Eerola, Kelly Jakubowski, Nikki Moran, Peter E Keller, Martin Clayton
Human interaction involves the exchange of temporally coordinated, multimodal cues. Our work focused on interaction in the visual domain, using music performance as a case for analysis due to its temporally diverse and hierarchical structures. We made use of two improvising duo datasets-(i) performances of a jazz standard with a regular pulse and (ii) non-pulsed, free improvizations-to investigate whether human judgements of moments of interaction between co-performers are influenced by body movement coordination at multiple timescales...
February 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29479917/neurosyphilis-in-anglo-american-composers-and-jazz-musicians
#16
REVIEW
Darko Breitenfeld, Davor Kust, Tomislav Breitenfeld, Marin Prpić, Marko Lucijanić, Davor Zibar, Vedran Hostić, Maja Franceschi, Ante Bolanča
Syphilis is a sexually transmitted, systemic disease caused by the spirochete bacterium Treponema pallidum. The most common mechanism of transmission is sexual intercourse. Although there are several hypotheses, the exact origin of the disease remains unknown. Newly published evidence suggests that the hypothesis supporting the theory of the American origin of the disease is the valid one. Among 1500 analyzed pathographies of composers and musicians, data on ten Anglo-American composers and jazz musicians having suffered from neurosyphilis (tertiary stage of the disease) were extracted for this report...
September 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29428927/dancing-for-healthy-aging-functional-and-metabolic-perspectives
#17
Josianne Rodrigues-Krause, Mauricio Krause, Alvaro Reischak-Oliveira
Context • Dancing has been used as a form of exercise to improve functional and metabolic outcomes during aging. The field lacks randomized, clinical trials (RCTs) evaluating metabolic outcomes related to dance interventions, but dancing may be a form of exercise that could induce positive effects on the metabolic health of older adults. However, primary studies seem very heterogonous regarding the trial designs, characteristics of the interventions, the methods for outcomes assessments, statistical powers, and methodological quality...
February 10, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29408646/utrophin-up-regulation-by-artificial-transcription-factors-induces-muscle-rescue-and-impacts-the-neuromuscular-junction-in-mdx-mice
#18
Cinzia Pisani, Georgios Strimpakos, Francesca Gabanella, Maria Grazia Di Certo, Annalisa Onori, Cinzia Severini, Siro Luvisetto, Stefano Farioli-Vecchioli, Irene Carrozzo, Antonio Esposito, Tamara Canu, Elisabetta Mattei, Nicoletta Corbi, Claudio Passananti
Up-regulation of the dystrophin-related gene utrophin represents a promising therapeutic strategy for the treatment of Duchenne Muscular Dystrophy (DMD). In order to re-program the utrophin expression level in muscle, we engineered artificial zinc finger transcription factors (ZF-ATFs) that target the utrophin 'A' promoter. We have previously shown that the ZF-ATF "Jazz", either by transgenic manipulation or by systemic adeno-associated viral delivery, induces significant rescue of muscle function in dystrophic "mdx" mice...
April 2018: Biochimica et biophysica acta. Molecular basis of disease
https://www.readbyqxmd.com/read/29364920/correlated-microtiming-deviations-in-jazz-and-rock-music
#19
Mathias Sogorski, Theo Geisel, Viola Priesemann
Musical rhythms performed by humans typically show temporal fluctuations. While they have been characterized in simple rhythmic tasks, it is an open question what is the nature of temporal fluctuations, when several musicians perform music jointly in all its natural complexity. To study such fluctuations in over 100 original jazz and rock/pop recordings played with and without metronome we developed a semi-automated workflow allowing the extraction of cymbal beat onsets with millisecond precision. Analyzing the inter-beat interval (IBI) time series revealed evidence for two long-range correlated processes characterized by power laws in the IBI power spectral densities...
2018: PloS One
https://www.readbyqxmd.com/read/29318615/playing-off-the-beat-applying-the-jazz-paradigm-to-psychotherapy
#20
David Read Johnson
A jazz paradigm is applied to traditional psychotherapy practice, illuminating the links between psychotherapy and the Romantic aesthetic tradition, primarily in the centrality of concepts such as attunement. Modernist disruptions of realism during the early 20th century, such as jazz, elaborated dissonant and improvisational artistic impulses that brought new vitality to their art forms. The psychotherapeutic relationship also has potential avenues for multilevel and discrepant communication that open possibilities of freedom...
February 2018: Journal of Clinical Psychology
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