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Cardiopulmonary test prediction

Jon Magne Letnes, Håvard Dalen, Elisabeth K Vesterbekkmo, Ulrik Wisløff, Bjarne M Nes
Aims: The majority of previous research on the association between cardiorespiratory fitness (CRF) and cardiovascular disease (CVD) is based on indirect assessment of CRF in clinically referred predominantly male populations. Therefore, our aim was to examine the associations between VO2peak measured by the gold-standard method of cardiopulmonary exercise testing and fatal and non-fatal coronary heart disease (CHD) in a healthy and fit population. Methods and results: Data on VO2peak from 4527 adults (51% women) with no previous history of cardiovascular or lung disease, cancer, and hypertension or use of antihypertensive medications participating in a large population-based health-study (The HUNT3 Study), were linked to hospital registries and the cause of death registry...
November 29, 2018: European Heart Journal
Kiran K Mirza, Mette H Jung, Per E Sigvardsen, Klaus F Kofoed, Marie B Elming, Kasper Rossing, Finn Gustafsson
Using four-dimensional (4D) cardiac computed tomography (CCT) scans at rest and immediately after exercise, we examined the right heart chamber sizes and systolic function and its association with exercise capacity in left ventricular assist device (LVAD) recipients. Fifteen patients with HeartMate (HM) II or 3 underwent echocardiography and maximal cardiopulmonary exercise test. Subsequently, contrast-enhanced CCT scans were performed at rest and immediately after two minutes of supine 25 Watt ergometer bike exercise...
November 27, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Yahui Zhang, Zhihao Jiang, Lin Qi, Lisheng Xu, Xingguo Sun, Xinmei Chu, Yanling Liu, Tianjing Zhang, Stephen E Greenwald
Objective: This study aimed to compare differences in cardiorespiratory function between untreated hypertensive subjects (UHS) and healthy subjects (HS) during cardiopulmonary exercise testing (CPET). Additionally, it also aimed to explore the potential mechanisms of different exercise responses in cardiorespiratory function before, during and after CPET. Methods: Thirty subjects (15 UHS and 15 HS) were enrolled. Photoplethysmography (PPG), respiratory signal, and ECG were simultaneously collected while subjects were performing CPET...
2018: Frontiers in Physiology
A E Harwood, S Pymer, L Hitchman, J Totty, T Wallace, G E Smith, D Carradice, S Carroll, I C Chetter
INTRODUCTION: Patients with abdominal aortic aneurysms (AAA) often have low exercise tolerance due to comorbidities and advance age. Cardiopulmonary exercise testing (CPET) is predictive of post-operative morbidity and mortality in patients with AAA. We aimed to assess the intra- and inter-rater reliability of both treadmill and cycle ergometer based CPET variables. METHODS: Patients with a AAA (>3.5cm) were randomised to treadmill or bike CPET. Participants were asked to perform two separate CPET tests seven days apart after a familiarisation protocol...
November 23, 2018: Annals of Vascular Surgery
Jane L Woodward, Mark Connolly, Patrick W Hennessy, Carey L Holleran, Gordhan B Mahtani, Gabrielle Brazg, Meghan Fahey, Kameswari Maganti, T George Hornby
Background: The 6-minute walk test (6MWT) is a common clinical assessment used to evaluate locomotor function in patients after stroke. Previous work suggests the 6MWT can estimate peak metabolic capacity (VO2peak) without cardiorespiratory assessments during graded exercise tests (GXTs) which may assist with exercise prescription. However, selected research also indicated increased heart rates (HRs) during 6MWTs beyond levels considered safe without GXTs. Objective: The goal of this study was to examine cardiorespiratory responses during 6MWTs and GXTs in individuals with chronic stroke and their associations with demographic or clinical characteristics...
November 26, 2018: Physical Therapy
Nicola Riccardo Pugliese, Iacopo Fabiani, Giulia Elena Mandoli, Giacinta Guarini, Gian Giacomo Galeotti, Mario Miccoli, Alberto Lombardo, Anca Simioniuc, Giovanni Bigalli, Roberto Pedrinelli, Frank L Dini
Aims: Peak cardiac power output-to-mass (CPOM) represents a measure of the rate at which cardiac work is delivered respect to the potential energy stored in left ventricular (LV) mass. We studied the value of CPOM and cardiopulmonary exercise test (CPET) in risk stratification of patients with heart failure (HF). Materials and results: We studied 159 patients with chronic HF (mean rest LV ejection fraction 30%) undergoing CPET and exercise stress echocardiography...
November 23, 2018: European Heart Journal Cardiovascular Imaging
Adam W Powell, Wayne A Mays, Sandra K Knecht, Clifford Chin
BACKGROUND: A transannular patch is often used in the contemporary surgical repair of tetralogy of Fallot. This can lead to significant pulmonary insufficiency and increased right ventricular volumes and ultimately pulmonary valve replacement. Cardiopulmonary exercise testing is used to assess exercise capacity in tetralogy of Fallot patients before pulmonary valve replacement. There is only few published literatures on how lung function affects functional capacity in tetralogy of Fallot patients repaired with a transannular patch...
November 26, 2018: Cardiology in the Young
Ingunn Skjørten, Janne Mykland Hilde, Morten Nissen Melsom, Jonny Hisdal, Viggo Hansteen, Kjetil Steine, Sjur Humerfelt
Background: Pulmonary hypertension (PH) in patients with COPD is associated with reduced exercise capacity. A subgroup of COPD patients has normal mean pulmonary artery pressure (mPAP) at rest, but develops high mPAP relative to cardiac output (CO) during exercise, a condition we refer to as exercise-induced pulmonary hypertension (EIPH). We hypothesized that COPD patients with EIPH could be identified by cardiopulmonary exercise test (CPET) and that these patients have lower exercise capacity and more abnormal CPET parameters compared to COPD patients with normal hemodynamic exercise response...
2018: International Journal of Chronic Obstructive Pulmonary Disease
Michael Furian, Deborah Flueck, Tsogyal D Latshang, Philipp M Scheiwiller, Sebastian Daniel Segitz, Séverine Mueller-Mottet, Christian Murer, Adrian Steiner, Silvia Ulrich, Thomas Rothe, Malcolm Kohler, Konrad E Bloch
Objective: To evaluate the effects of altitude travel on exercise performance and symptoms in lowlanders with COPD. Design: Randomized crossover trial. Setting: University Hospital Zurich (490 m), research facility in mountain villages, Davos Clavadel (1,650 m) and Davos Jakobshorn (2,590 m). Participants: Forty COPD patients, Global Initiative for Obstructive Lung Disease (GOLD) grade 2-3, living below 800 m, median (quartiles) age 67 y (60; 69), forced expiratory volume in 1 second 57% predicted (49; 70)...
2018: International Journal of Chronic Obstructive Pulmonary Disease
Joshua R Smith, Jose R Medina-Inojosa, Veronica Layrisse, Steve R Ommen, Thomas P Olson
Hypertrophic obstructive cardiomyopathy (HOCM) patients exhibit compromised peak exercise capacity (VO₂peak). Importantly, severely reduced VO₂peak is directly related to increased morbidity and mortality in these patients. Therefore, we sought to determine clinical predictors of VO₂peak in HOCM patients. HOCM patients who performed symptom-limited cardiopulmonary exercise testing between 1995 and 2016 were included for analysis. Peak VO₂ was reported as absolute peak VO₂, indexed to body weight and analyzed as quartiles, with quartile 1 representing the lowest VO₂peak...
November 18, 2018: Journal of Clinical Medicine
Sheng-Hui Tuan, Hung-Tzu Su, Yi-Jen Chen, Chia-Hsin Chen, Wan-Jung Tsai, Guan-Bo Chen, Ko-Long Lin
The oxygen uptake efficiency slope (OUES) is a well-established substitute for maximum oxygen uptake ((Equation is included in full-text article.)O2 max) in submaximal exercise effort among adolescents and adults. Few studies have analyzed the exercise capacity (EC) and OUES of children aged 4 to 6 (preschoolers). Body fat has been proved to negatively affect EC among schoolchildren. The purposes of this study were to assess the capacity of preschoolers in achieving (Equation is included in full-text article...
November 2018: Medicine (Baltimore)
Ernesto Crisafulli, Marina Aiello, Panagiota Tzani, Antonella Ielpo, Chiara Longo, Veronica Alfieri, Giuseppina Bertorelli, Alfredo Chetta
BACKGROUND: In patients with COPD, limited data have been reported concerning the association between dyspnea perception and exercise tests. Moreover, the perception of dyspnea has not been analyzed in patients with the same severity of air-flow obstruction. The aim of our study was to evaluate the relationship between the degree of dyspnea and exercise capacity in subjects with COPD who had the same severity of air-flow obstruction. METHODS: We assessed dyspnea perception and maximum exercise capacity by using the modified Medical Research Council dyspnea scale (mMRC) questionnaire and by using the symptom-limited incremental cardiopulmonary exercise test, respectively...
November 13, 2018: Respiratory Care
H-Y Tsai, W-J Tsai, L-Y Kuo, Y-S Lin, B-Y Chen, W-H Lin, S-L Shen, H-Y Huang
OBJECTIVES: The ventilatory efficiency and functional capacity measured by the cardiopulmonary exercise test (CPET) have been used as important prognostic variables in congestive heart failure. This study sought to identify whether these predictors before heart transplantation (HTX) play a key role in predicting adverse events in patients with heart failure after HTX. METHODS: This was a retrospective cohort study design. HTX recipients were included for analysis...
November 2018: Transplantation Proceedings
Gisela Arsa, Fernanda Cordoba Lanza, Lucieli Teresa Cambri, Ednei Luiz Antonio, Neif Murad, Marco Túlio de Mello, Alexandra Alberto Santos, Paulo de Tarso Camillo de Carvalho, José Antonio Silva-Junior, Danilo Sales Bocalini, Barbara Sampaio Dias Martins Mansano, Paulo José Ferreira Tucci, Andrey Jorge Serra
This study compared maximum oxygen consumption (VO2 max) on a 20-meter multistage shuttle run test (20-Srt) with a cardiopulmonary exercise test (CPET) to determine a VO2 max prediction equation for a 20-Srt in children aged 6-10 years. Eighty healthy children performed the CPET on a treadmill, while the 20-Srt took place on a sports court. Heart rate (HR) was measured and the expired gases were continuously measured breath-by-breath using a portable gas analyzer. The VO2 max was lower (p<0.05) in CPET than 20-Srt for all, female, and male participants, respectively (46...
November 6, 2018: International Journal of Sports Medicine
Andreza L Gomes, Vanessa A Mendonça, Tatiane Dos Santos Silva, Crislaine K V Pires, Liliana P Lima, Alcilene M Silva, Ana Cristina R Camargos, Camila D C Neves, Ana C R Lacerda, Hércules R Leite
BACKGROUND: Previous studies speculated that the Incremental Shuttle Walking Test (ISWT) is a maximal test in children and adolescents, however comparison between ISWT with cardiopulmonary exercise test has not yet performed. Furthermore, there is no regression equation available in the current literature to predict oxygen peak consumption (VO2 peak) in this population. This study aimed to assesses and correlate the cardiorespiratory responses of the ISWT with the cardiopulmonary exercise (CEPT) and to develop and validate a regression equation to predict VO2 peak in healthy sedentary adolescent boys...
2018: PloS One
Małgorzata Kurpaska, Paweł Krzesiński, Grzegorz Gielerak, Beata Uziębło-Życzkowska, Małgorzata Banak, Katarzyna Piotrowicz, Adam Stańczyk
INTRODUCTION: Arterial hypertension (AH) can lead to the development of heart failure. AIM: Evaluating the relationship between parameters of exercise capacity assessed via a six-minute walk test (6MWT) and cardiopulmonary exercise test (CPET), with a hemodynamic assessment via impedance cardiography (ICG), in patients with AH. METHODS: Exercise capacity was assessed in 98 hypertensive patients (54.5 ± 8.2 years) by means of oxygen uptake (VO2 ) get from CPET, 6MWT distance (6MWTd) and hemodynamic parameters measured by ICG: heart rate (HR), stroke volume (SV), cardiac output (CO)...
October 31, 2018: Clinical and Experimental Hypertension: CHE
Anne S Ersbøll, Annemie S Bojer, Maria G Hauge, Marianne Johansen, Peter Damm, Finn Gustafsson, Niels G Vejlstrup
Background Long-term clinical studies of peripartum cardiomyopathy ( PPCM ) are few. We aimed to measure the long-term effect of PPCM on cardiac function in comparison with the long-term effects of severe preeclampsia and uncomplicated pregnancy. Methods and Results A nationwide Danish cohort of women diagnosed with PPCM from 2005 to 2014 ( PPCM group) were invited to participate in a clinical follow-up study including maximal cardiopulmonary exercise testing and cardiac magnetic resonance imaging. Matched women with previous severe preeclampsia (preeclampsia group) and previous uncomplicated pregnancies (uncomplicated pregnancies group) served as comparison groups...
October 16, 2018: Journal of the American Heart Association
Patricia Corzo, Anna Pros, Juana Martinez-Llorens, Luis Molina, Stephanie Fenxi Ling, Eva Balcells
INTRODUCTION: Diffusing capacity for carbon monoxide (DLco) reduction is the first detectable pulmonary functional test (PFT) change in systemic sclerosis (SSc)-related pulmonary complications. reduction in patients without cardiopulmonary alterations has also been observed; a good characterisation of these patients is lacking. The objective of this study is to describe the characteristics of SSc patients with isolated DLco reduction and compare these patients to SSc patients with DLco reduction with a known cause...
December 2018: Clinical Rheumatology
Marco Ranucci, Valeria Pistuddi, Umberto Di Dedda, Lorenzo Menicanti, Carlo De Vincentiis, Ekaterina Baryshnikova
Platelet dysfunction after cardiac surgery is a determinant of postoperative bleeding. The existing guidelines suggest the use of desmopressin and/or platelet concentrate transfusions in case of platelet dysfunction in bleeding patients, but no cut-off values for platelet activity exist in the literature. The Platelet Function in the Operating Room (PLATFORM) study aims to identify the relationship between platelet function after cardiopulmonary bypass and severe bleeding, finding adequate predictive values of platelet function for severe bleeding...
October 26, 2018: Platelets
Carlos Ac Hossri, Isabela Pm Alves de Souza, Joana St de Oliveira, Luiz E Mastrocola
BACKGROUND: Oxygen-uptake efficiency slope (OUES) is an objective measure of functional capacity that does not require a maximal effort but is considerably dependent on anthropometric variables and requires the generation of an appropriate reference value in children. This study aimed to establish normal reference values for OUES/kg in children with and without congenital heart diseases. Besides that, reference values are presented secondarily for OUES per body surface area (OUES/BSA)...
October 24, 2018: European Journal of Preventive Cardiology
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