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Pharmacy research

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https://www.readbyqxmd.com/read/28214219/perpetuating-stigma-or-reducing-risk-perspectives-from-naloxone-consumers-and-pharmacists-on-pharmacy-based-naloxone-in-2-states
#1
Traci C Green, Patricia Case, Haley Fiske, Janette Baird, Shachan Cabral, Dina Burstein, Victoriana Schwartz, Nathan Potter, Alexander Y Walley, Jeffrey Bratberg
OBJECTIVES: Little is known about attitudes of pharmacists and consumers to pharmacy naloxone. We examined perceptions and experiences of pharmacy naloxone from people with opioid use disorder, patients taking chronic opioids for pain, caregivers of opioid users, and pharmacists from 2 early pharmacy naloxone adopter states: Massachusetts and Rhode Island. DESIGN: Eight focus groups (4 per state) were held in October to December 2015. SETTING AND PARTICIPANTS: Participants were recruited from pharmacies, health clinics, and community organizations; pharmacists were recruited from professional organizations and pharmacy colleges...
February 14, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28213493/development-of-the-critical-care-pharmacotherapy-trials-network
#2
Seth R Bauer, Prasad E Abraham, Jeffrey F Barletta, Gretchen M Brophy, Brian L Erstad, Jeffrey P Gonzales, Curtis E Haas, Robert MacLaren, Eric W Mueller, Keith M Olsen, Ishaq Lat
PURPOSE: The development of the Critical Care Pharmacotherapy Trials Network (CCPTN) as a model for practice-based pharmacotherapy research is described. SUMMARY: The CCPTN was formed in 2010 as a collaborative research network dedicated to scientific investigation in the field of critical care pharmacotherapy. The CCPTN organizational structure is consistent with many professional pharmacy and interdisciplinary organizations and organized into 3 primary domains: executive committee, working committees, and network membership...
March 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28209159/do-coursework-summative-assessments-predict-clinical-performance-a-systematic-review
#3
Rebecca Terry, Wayne Hing, Robin Orr, Nikki Milne
BACKGROUND: Two goals of summative assessment in health profession education programs are to ensure the robustness of high stakes decisions such as progression and licensing, and predict future performance. This systematic and critical review aims to investigate the ability of specific modes of summative assessment to predict the clinical performance of health profession education students. METHODS: PubMed, CINAHL, SPORTDiscus, ERIC and EMBASE databases were searched using key terms with articles collected subjected to dedicated inclusion criteria...
February 16, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28198174/a-comparative-review-of-common-laxatives-in-the-treatment-of-constipation
#4
Kyle Fiorini, Steven Sato, Christopher M Schlachta, Nawar A Alkhamesi
Constipation is a common condition that affects people all over the world. Frequently sought out solution to this problem consists of laxatives, especially since these medications are easily accessible over-the-counter in most pharmacies. This has lead laxative spending in North America alone to be approximately $500 million per year. Due to this large expenditure, a review of the available laxative data was completed and common laxative classes were evaluated and contrasted for the purposes of evaluating cost-effectiveness...
February 14, 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/28197420/the-challenges-of-electronic-health-records-and-diabetes-electronic-prescribing-implications-for-safety-net-care-for-diverse-populations
#5
REVIEW
Neda Ratanawongsa, Lenny L S Chan, Michelle M Fouts, Elizabeth J Murphy
Widespread electronic health record (EHR) implementation creates new challenges in the diabetes care of complex and diverse populations, including safe medication prescribing for patients with limited health literacy and limited English proficiency. This review highlights how the EHR electronic prescribing transformation has affected diabetes care for vulnerable patients and offers recommendations for improving patient safety through EHR electronic prescribing design, implementation, policy, and research. Specifically, we present evidence for (1) the adoption of RxNorm; (2) standardized naming and picklist options for high alert medications such as insulin; (3) the widespread implementation of universal medication schedule and language-concordant labels, with the expansion of electronic prescription 140-character limit; (4) enhanced bidirectional communication with pharmacy partners; and (5) informatics and implementation research in safety net healthcare systems to examine how EHR tools and practices affect diverse vulnerable populations...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28182023/a-randomized-single-blind-parallel-group-study-comparing-monoherbal-formulation-containing-holarrhena-antidysenterica-extract-with-mesalamine-in-chronic-ulcerative-colitis-patients
#6
Sarika Johari, Tejal Gandhi
BACKGROUND: Incidences of side effects and relapses are very common in chronic ulcerative colitis patients after termination of the treatment. AIMS AND OBJECTIVES: This study aims to compare the treatment with monoherbal formulation of Holarrhena antidysenterica with Mesalamine in chronic ulcerative colitis patients with special emphasis to side effects and relapse. SETTINGS AND DESIGN: Patients were enrolled from an Ayurveda Hospital and a private Hospital, Gujarat...
July 2016: Ancient Science of Life
https://www.readbyqxmd.com/read/28179739/engaging-in-collaborative-research-focus-on-the-pharmacy-practitioner
#7
Melissa Badowski, Joseph E Mazur, Simon W Lam, Marta Miyares, Lucas Schulz, Sarah Michienzi
Research offers an opportunity for investigators to explore unanswered questions, highlight best practices, and engage in collaboration. Clinical research can engage health care professionals to identify treatments or procedures to enhance patient care, quality of life, and outcomes. Research may also include experiences in a unique practice site or teaching methodology of trainees, staff, or patients. The goal of research is to improve individual patient care via dissemination of knowledge through publications...
January 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/28179712/identifying-best-practices-for-and-utilities-of-the-pharmacy-curriculum-outcome-assessment-examination
#8
REVIEW
Timothy Y Mok, Frank Romanelli
Objective. A review was conducted to determine implementation strategies, utilities, score interpretation, and limitations of the Pharmacy Curriculum Outcome Assessment (PCOA) examination. Methods. Articles were identified through the PubMed and American Journal of Pharmaceutical Education, and International Pharmaceutical Abstracts databases using the following terms: "Pharmacy Curriculum Outcomes Assessment," "pharmacy comprehensive examination," and "curricular assessment." Studies containing information regarding implementation, utility, and predictive values for US student pharmacists, curricula, and/or PGY1/PGY2 residents were included...
December 25, 2016: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28156503/health-care-utilization-and-costs-at-end-of-life-among-patients-with-leukemia-or-lymphoma-in-a-regional-cancer-registry-insurance-claims-linked-database
#9
Catherine R Fedorenko, Karma L Kreizenbeck, Ted Conklin, Bruce Smith, Gary H Lyman, Scott David Ramsey
: 184 Background: End-of-life (EOL) care for persons with hematologic malignancies is variable and often involves high-intensity services at death approaches, which may not reflect patient or family preferences. We characterized healthcare utilization and associated costs in the last 30 days of life among subjects with leukemia or lymphoma to better understand patterns of care in this population. METHODS: We linked enrollment and claims records from two regional commercial insurers to Surveillance, Epidemiology, and End Results (SEER) records for patients diagnosed with leukemia or lymphoma in Western Washington state between January 1, 2007 and December 31, 2015...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156501/using-cancer-registry-records-linked-with-health-insurance-records-to-measure-costs-and-services-at-end-of-life
#10
Catherine R Fedorenko, Kristine Stickney, Cara L McDermott, Ted Conklin, Bruce Smith, Gary H Lyman, Scott David Ramsey
: 186 Background: Studies suggest that end-of-life (EOL) care for persons with cancer in the United States is variable and often misaligned with patient and family preferences. To better understand these issues, we developed reports on high-priority quality indicators and costs at EOL. METHODS: Surveillance, Epidemiology, and End Results (SEER) records for solid tumor patients diagnosed with cancer in Western Washington state between 1/1/2007 and 12/31/2015 were linked with enrollment and claims from two regional commercial insurers...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28154015/potential-ways-to-address-shortage-situations-of-mo-99-tc-99m
#11
Leah Filzen, Lacey Ellingson, Andrew Paulsen, Joseph Hung
: Technetium 99m (Tc-99m) is the most common radioisotope used in nuclear medicine, which is produced in a nuclear reactor from the decay of molybdenum-99 (Mo-99). There are only a few aging nuclear reactors around the world that produce Mo-99 and one of the major contributors, the NRU (National Research Universal, Canada), will cease production on October 31, 2016. The NRU produces approximately 40% of the world's Mo-99 supply, so with its impending shut down, shortages of Mo-99/Tc-99m are expected...
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28153705/supporting-patients-with-mental-illness-deconstructing-barriers-to-community-pharmacist-access
#12
Samantha Calogero, Charles F Caley
OBJECTIVES: To discuss the barriers faced by individuals with mental health conditions attempting to access their community pharmacists and to propose solutions toward deconstructing those barriers. SUMMARY: Given the prevalence of mental illness and the frequency at which psychotropic medications are dispensed, community pharmacists have a daily opportunity to engage patients with mental illness and be active participants in community-based mental health care. Yet multiple barriers affect patient access to community pharmacists...
January 30, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28152723/a-multidisciplinary-quality-improvement-project-to-improve-the-safety-of-oral-chemotherapy-in-hospitalized-patients
#13
Amer Sidani, Gelenis Calzadilla Domingo, Diana Sullivan, Katherine Sencion, Dominic Ho, Christina Haaf, Adam Bursua, Neeta K Venepalli
: 110 Background: At the University of Illinois Hospital and Health Sciences System (UIC), inpatient IV chemotherapy administration occurs in the setting of specific protocols and multidisciplinary safety assessments while oral chemotherapy agent (OCA) inpatient administration occurs less formally. Baseline 8 week review of 174 admissions to the oncology service revealed that of 16 patients (9.2%) on outpatient OCA, 50% received OCAs while inpatient, with 12. 55% having a formal chemotherapy note in place...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152714/data-collection-for-care-pathways-in-the-cleveland-clinic-health-system
#14
Chad W Cummings, Marc A Shapiro, Dennis Urbanek, Brian James Bolwell
: 115 Background: Care pathways are established methods of reducing healthcare costs and disparities in oncology care. To demonstrate their impact, health systems must measure and report data on care pathway adherence and outcomes in near real-time. Automating data abstraction across a health system for oncology is difficult due to the amount and detail of data required. Manual abstraction of data is considered slow and costly. Many consider Electronic Medical Record (EMR) integration of care pathways essential in order to successfully implement and assess...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152686/patient-centered-outcomes-with-post-approval-nivolumab-in-metastatic-nsclc-at-the-cleveland-clinic-taussig-cancer-institute-tci
#15
Katherine Glass, Alicia M Redden, Nathan A Pennell, James Stevenson, Vamsidhar Velcheti, Emily Van Wagoner, Chad W Cummings, Brian James Bolwell
: 29 Background: Patient-centered outcomes are important quality metrics of value-based cancer care. For NSCLC, these include chemotherapy administration within 30 days of death and end of life hospitalizations. Nivolumab was initially FDA approved in March 2015 for second-line therapy of squamous NSCLC and subsequently for non-squamous NSCLC. To evaluate the impact of post-approval nivolumab use on patient-centered outcomes, a retrospective review was performed of patients (pts) with metastatic NSLCC receiving nivolumab at TCI main campus and regional centers...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28151951/comorbidities-of-hiv-infection-and-health-care-seeking-behavior-among-hiv-infected-patients-attending-public-sector-healthcare-facilities-in-kwazulu-natal-a-cross-sectional-study
#16
Manimbulu Nlooto
BACKGROUND: HIV-infected people may present with co-infections, comorbidities, and side effects associated with antiretroviral therapy. This study explored the prevalence of comorbid health problems and determined the extent of the use of traditional medicine for treatment of co-infections, comorbidities of HIV infection and side effects. METHODS: A cross sectional study, using researcher-administered questionnaires, was carried out among HIV-infected patients in eight public sector healthcare facilities in KwaZulu-Natal between April and October 1024...
2017: PloS One
https://www.readbyqxmd.com/read/28128095/antimicrobial-prescribing-patterns-in-a-large-tertiary-hospital-in-shanghai-china
#17
Yuan-Yuan Wang, Ping Du, Fang Huang, Dong-Jie Li, Jun Gu, Fu-Ming Shen, Yuan-Ying Jiang
Whilst the 'Principles of clinical use of antibiotics' was released by the Ministry of Health of the People's Republic of China in 2004, limited research has been conducted to evaluate the quality of antibiotic use in real-world practice. In this study, we sought to examine antimicrobial prescribing patterns in a large tertiary hospital in Shanghai, China. De-identified outpatient and emergency department pharmacy records containing antimicrobials were extracted from the hospital electronic health records system...
December 2016: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28125699/uptake-and-acceptability-of-oral-hiv-self-testing-among-community-pharmacy-clients-in-kenya-a-feasibility-study
#18
Peter M Mugo, Murugi Micheni, Jimmy Shangala, Mohamed H Hussein, Susan M Graham, Tobias F Rinke de Wit, Eduard J Sanders
BACKGROUND: While HIV testing and counselling is a key entry point for treatment as prevention, over half of HIV-infected adults in Kenya are unaware they are infected. Offering HIV self-testing (HST) at community pharmacies may enhance detection of undiagnosed infections. We assessed the feasibility of pharmacy-based HST in Coastal Kenya. METHODS: Staff at five pharmacies, supported by on-site research assistants, recruited adult clients (≥18 years) seeking services indicative of HIV risk...
2017: PloS One
https://www.readbyqxmd.com/read/28125406/the-association-between-chronic-pancreatitis-and-the-inos-2087a-g-polymorphism
#19
V Pădureanu, Anca Ştefania Enescu, Isabela Siloşi, Maria Forţofoiu, Aurelia Enescu, Maria Bogdan, M C Forţofoiu, Amelia Genunche Dumitrescu, Diana Rodica Tudorascu, A Mita, Ioana Streata, M Ioana, F Petrescu, A Săftoiu
Chronic pancreatitis is morphologically characterized by ductal dysplasia, breeding grounds for the proliferation of the ductal cells, the degenerative changes in pancreatic acinar cells and fibrosis, and it is defined on the basis of the clinical, morphological and functional criteria. The aim of our study is to examine the existence of a possible correlation between the iNOS-2087A>G polymorphism and chronic pancreatitis by means of the genetic analysis. We have conducted the study at the Gastroenterology Clinic and the Research Center of Gastroenterology and Hepatology of the University of Medicine and Pharmacy, Craiova, between March 2015 - September 2016...
January 25, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28125370/a-systematic-review-of-the-effect-of-cancer-treatment-on-work-productivity-of-patients-and-caregivers
#20
Khalid M Kamal, Jordan R Covvey, Ankur Dashputre, Somraj Ghosh, Surbhi Shah, Monali Bhosle, Christopher Zacker
BACKGROUND: Cancer is a leading cause of death with substantial financial costs. While significant data exist on the economic burden of care, less is known about the indirect costs of treatment and, specifically, the effect on work productivity of patients and their caregivers. To examine the full effect of cancer and the potential value of new therapies, all aspects of care, including indirect costs and patient-reported outcomes, should be evaluated. OBJECTIVE: To perform a systematic review of the literature examining the effect of cancer treatment on work productivity in patients and their caregivers...
February 2017: Journal of Managed Care & Specialty Pharmacy
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