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https://www.readbyqxmd.com/read/27921195/new-developments-in-the-pharmacodynamics-and-pharmacokinetics-of-combination-of-chinese-medicine-and-western-medicine
#1
REVIEW
Di Liu, Xiao-Chun Liang
It is very common to use Chinese medicine (CM) combined with Western medicine (WM) in clinical practice. The appropriate combination of CM with WM can reduce toxicity and enhance effects in order to make the best use of advantages and bypass the disadvantages. However, an inappropriate combination can not only affect the curative effect but even cause death. Therefore, strengthening the complementary advantages of the CM and WM to improve the therapeutic efficacy and reduce side effects has become an important research topic of clinical medicine and pharmacy...
December 5, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27919875/the-layered-learning-practice-model-lessons-learned-from-implementation
#2
Nicole R Pinelli, Stephen F Eckel, Maihan B Vu, Morris Weinberger, Mary T Roth
PURPOSE: Pharmacists' views about the implementation, benefits, and attributes of a layered learning practice model (LLPM) were examined. METHODS: Eligible and willing attending pharmacists at the same institution that had implemented an LLPM completed an individual, 90-minute, face-to-face interview using a structured interview guide developed by the interdisciplinary study team. Interviews were digitally recorded and transcribed verbatim without personal identifiers...
December 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27919396/think-time-a-novel-approach-to-analysis-of-clinicians-behavior-after-reduction-of-drug-drug-interaction-alerts
#3
Richard Schreiber, Julia A Gregoire, Jacob E Shaha, Steven H Shaha
OBJECTIVES: Pharmacologic interaction alerting offers the potential for safer medication prescribing, but research reveals persistent concerns regarding alert fatigue. Research studies have tried various strategies to resolve this problem, with low overall success. We examined the effects of targeted alert reduction on clinician behavior in a resource constrained hospital. METHODS: A physician and a pharmacy informaticist reduced alert levels of several drug-drug interactions (DDI) that clinicians almost always overrode with approval from and knowledge of the medical staff...
January 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27913988/experience-and-attitudes-toward-informed-consent-in-pharmacy-practice-research-do-pharmacists-care
#4
Dušanka M Krajnović, Dragana D Jocić
The experience and attitudes of pharmacists towards research ethics through pharmacy practice research is largely unknown. This study sought to examine the pharmacists' experience if they were research participants and their attitudes on the importance of informed consent in research practice. A cross-sectional survey was employed to achieve the aims of this study. The majority of 433 participating pharmacists were female (86.1%); the average age was 43.2 ± 9.5 years, and their average working experience was 15...
December 2, 2016: Science and Engineering Ethics
https://www.readbyqxmd.com/read/27913984/basal-insulin-persistence-associated-factors-and-outcomes-after-treatment-initiation-a-retrospective-database-study-among-people-with-type-2-diabetes-mellitus-in-japan
#5
Irene Hadjiyianni, Urvi Desai, Shuichi Suzuki, Jasmina I Ivanova, Dachuang Cao, Noam Y Kirson, Dai Chida, Caroline Enloe, Howard G Birnbaum, Magaly Perez-Nieves
INTRODUCTION: The objective of this study was to assess basal insulin persistence, associated factors, and economic outcomes for insulin-naïve people with type 2 diabetes mellitus (T2DM) in Japan. METHODS: People aged at least 18 years with T2DM with first claim for basal insulin between May 2006 and April 2013 (index date), no insulin use before index date, and continuous insurance coverage for 6 months before (baseline) and 12 months after index date were selected from the Japan Medical Center Database...
December 2, 2016: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/27908657/sex-and-gender-based-analysis-in-pharmacy-practice-research-a-scoping-review
#6
Lisa McCarthy, Emily Milne, Nancy Waite, Martin Cooke, Katie Cook, Feng Chang, Beth A Sproule
BACKGROUND: Recognizing the potential effect of sex and gender on health outcomes, there is a shift toward conducting sex and gender-based analysis (SGBA) within health research. However, little is known about the extent to which SGBA has been incorporated into pharmacy practice research. OBJECTIVES: To understand the extent to which SGBA is included in pharmacy practice research. METHOD: Scoping review of English-language studies identified through MEDLINE, Embase, International Pharmacy Abstracts (IPA), and CINAHL (inception to Jan 2014)...
November 19, 2016: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/27901600/the-role-of-the-built-environment-how-decentralized-nurse-stations-shape-communication-patient-care-processes-and-patient-outcomes
#7
Kevin Real, Shoshana H Bardach, David R Bardach
Increasingly, health communication scholars are attending to how hospital built environments shape communication, patient care processes, and patient outcomes. This multimethod study was conducted on two floors of a newly designed urban hospital. Nine focus groups interviews were conducted with 35 health care professionals from 10 provider groups. Seven of the groups were homogeneous by profession or level: nursing (three groups), nurse managers (two groups), and one group each of nurse care technicians ("techs") and physicians...
November 30, 2016: Health Communication
https://www.readbyqxmd.com/read/27896894/perspectives-of-resettled-african-refugees-on-accessing-medicines-and-pharmacy-services-in-queensland-australia
#8
Kim Bellamy, Remo Ostini, Nataly Martini, Therese Kairuz
OBJECTIVES: The aim of this study was to explore the barriers to accessing medicines and pharmacy services among refugees in Queensland, Australia, from the perspectives of resettled African refugees. METHODS: A generic qualitative approach was used in this study. Resettled African refugees were recruited via a purposive snowball sampling method. The researcher collected data from different African refugee communities, specifically those from Sudanese, Congolese and Somalian communities...
November 29, 2016: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27895442/translation-of-the-medical-fear-survey-to-serbian-psychometric-properties
#9
J Djokovic, B Milovanovic, J R Milovanovic, O Milovanovic, I Stojic, S Mrvic, M Kostic, S Stefanovic, S M Jankovic
BACKGROUND: Medical Fear Survey (MFS) is an instrument designed for measuring fear of medical and related treatments. OBJECTIVE: Aim of the present study was MFS translation into Serbian, measurement of its psychometric properties and MFS validation using other Blood-injury-injections and related stimuli instruments that have been translated from English into Serbian. METHOD: After obtaining permission from the author of the original MFS, double forward translation from English to Serbian and backward translation to English were conducted in ten steps, according to International Society for Pharmacoeconomics and Outcomes Research (ISPOR) guidelines...
January 2016: Hippokratia
https://www.readbyqxmd.com/read/27891779/using-insurance-claims-data-to-identify-and-estimate-critical-periods-in-pregnancy-an-application-to-antidepressants
#10
Elizabeth C Ailes, Regina M Simeone, April L Dawson, Emily E Petersen, Suzanne M Gilboa
BACKGROUND: Health insurance claims are a rich data source to examine medication use in pregnancy. Our objective was to identify pregnant women, their pregnancy outcomes, and date of their last menstrual period (LMP), and to estimate antidepressant dispensations in pregnancy. METHODS: From a literature search, we identified diagnosis and procedure codes indicating the end of a pregnancy. Using Truven Health MarketScan(®) Commercial Claims and Encounters Databases, we identified all inpatient admissions and outpatient service claims with these codes...
November 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27891528/preparing-nursing-home-data-from-multiple-sites-for-clinical-research-a-case-study-using-observational-health-data-sciences-and-informatics
#11
Richard D Boyce, Steven M Handler, Jordan F Karp, Subashan Perera, Charles F Reynolds
INTRODUCTION: A potential barrier to nursing home research is the limited availability of research quality data in electronic form. We describe a case study of converting electronic health data from five skilled nursing facilities to a research quality longitudinal dataset by means of open-source tools produced by the Observational Health Data Sciences and Informatics (OHDSI) collaborative. METHODS: The Long-Term Care Minimum Data Set (MDS), drug dispensing, and fall incident data from five SNFs were extracted, translated, and loaded into version 4 of the OHDSI common data model...
2016: EGEMS
https://www.readbyqxmd.com/read/27890394/purchase-habits-use-of-paracetamol-and-information-sources-on-a-reregulated-swedish-pharmacy-market-a-population-based-study
#12
T Hedenrud, H Håkonsen
Considering the general lack of knowledge on how over-the-counter paracetamol is used combined with the reported increase in paracetamol poisonings after the reregulation of the Swedish pharmacy market in 2009, we aimed to analyze purchase habits and use of paracetamol in Sweden. A further aim was to investigate sources of information about paracetamol. Data were collected in October 2015 through the Citizen Panel, a Web-based panel encompassing over 50,000 Swedes. A stratified sample of 6000 (aged 18 years and older) was emailed a survey invitation...
November 19, 2016: Health Policy
https://www.readbyqxmd.com/read/27889507/cyp2c9-genotypes-modify-benzodiazepine-related-fall-risk-original-results-from-three-studies-with-meta-analysis
#13
Annelies C Ham, Gijsbertus Ziere, Linda Broer, Karin M A Swart, Anke W Enneman, Suzanne C van Dijk, Janneke P van Wijngaarden, Nikita L van der Zwaluw, Elske M Brouwer-Brolsma, Rosalie A M Dhonukshe-Rutten, Natasja M van Schoor, M Carola Zillikens, Teun van Gelder, Oscar J de Vries, Paul Lips, Dorly J H Deeg, Lisette C P G M de Groot, Albert Hofman, Renger F Witkamp, André G Uitterlinden, Bruno H Stricker, Nathalie van der Velde
OBJECTIVE: To investigate whether the CYP2C9*2 and *3 variants modify benzodiazepine-related fall risk. DESIGN: Three prospective studies; the Rotterdam Study, B-PROOF, and LASA. SETTING: Community-dwelling individuals living in or near five Dutch cities. PARTICIPANTS: There were 11,485 participants aged ≥55 years. MEASUREMENTS: Fall incidents were recorded prospectively. Benzodiazepine use was determined using pharmacy dispensing records or interviews...
November 23, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27887691/cost-effectiveness-of-achieving-targets-of-low-density-lipoprotein-particle-number-versus-low-density-lipoprotein-cholesterol-level
#14
Michael Grabner, Deborah A Winegar, Rajeshwari S Punekar, Ralph A Quimbo, Mark J Cziraky, William C Cromwell
A recent analysis of a commercially insured US population found fewer cardiovascular disease (CVD) events in high-risk patients attaining low levels of low-density lipoprotein (LDL), as measured by LDL particle number (LDL-P) versus low LDL cholesterol (LDL-C). Here, we investigated the cost effectiveness of LDL-lowering therapy guided by LDL-P. Patients were selected from the HealthCore Integrated Research Database and followed for 12 to 36 months. Patients who achieved LDL-P <1,000 nmol/l were placed into the LDL-P cohort, whereas those without LDL-P tests, but who achieved LDL-C <100 mg/dl, were placed into the LDL-C cohort...
October 31, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27885711/the-importance-of-research-and-scholarly-activity-in-pharmacy-training
#15
Eli N Deal, Paul M Stranges, Whitney D Maxwell, Jennifer Bacci, Emily J Ashjian, David L DeRemer, Sandra L Kane-Gill, Nicholas B Norgard, Lauren Dombrowski, Robert B Parker
Regardless of practice setting, it is imperative that pharmacists be able to either participate in generating new knowledge or use the ever-expanding body of literature to guide patient care. However, competing priorities in Pharm.D. curricula and residency training programs have resulted in limited emphasis on acquiring research and scholarly skills. Factors likely contributing to this reduced focus include the lack of curricular and postgraduate training standards emphasizing the development of research skills, time to commit to scholarly activity, and accessibility to experienced mentors...
November 25, 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/27883003/opportunities-to-develop-the-professional-role-of-community-pharmacists-in-the-care-of-patients-with-asthma-a-cross-sectional-study
#16
Kim Watkins, Aline Bourdin, Michelle Trevenen, Kevin Murray, Peter A Kendall, Carl R Schneider, Rhonda Clifford
There are many indications in Australia and globally that asthma management is suboptimal. Ideally, patients need to proactively self-manage the condition with the support of health professionals. Community pharmacists are a highly accessible resource for patients but currently provide inconsistent services. General practitioners also face many barriers to the provision of chronic disease management for asthma patients. The aim of this research was to characterise patients with asthma who present to community pharmacy...
November 24, 2016: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/27882838/a-pragmatic-randomized-trial-comparing-telephone-based-enhanced-pharmacy-care-and-usual-care-to-support-smoking-cessation
#17
Jason Gong, Christine L Baker, Kelly H Zou, Marianna Bruno, Zhanna Jumadilova, David Lawrence, Beth Wilson, Cynthia Ewel
BACKGROUND: Smoking is the leading preventable cause of death, and tobacco control professionals continue to make progress in cessation efforts. Pharmacists can assist smokers seeking to quit by offering counseling on smoking cessation pharmacotherapies. Pragmatic randomized trials are useful for investigating practical questions about an intervention's risks, benefits, and costs in routine clinical practice. OBJECTIVE: To evaluate an enhanced pharmacy care (EPC) program involving personalized pharmacist-provided telephone counseling for supporting prescription smoking cessation medications compared with usual care (UC)...
December 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27882832/geographic-variation-in-the-quality-and-cost-of-care-for-patients-with-rheumatoid-arthritis
#18
Jason Shafrin, Arijit Ganguli, Yuri Sanchez Gonzalez, Jin Joo Shim, Seth A Seabury
BACKGROUND: There is considerable push to improve value in health care by simultaneously increasing quality while lowering or containing costs. However, for diseases that are best treated with comparatively expensive treatments, such as rheumatoid arthritis (RA), there could be tension between these aims. In this study, we measured geographic variation in quality, access, and cost for patients with RA, a disease with effective but costly specialty treatments. OBJECTIVE: To assess the geographic differences in the quality, access, and cost of care for patients with RA...
December 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27882579/learner%C3%A2-%C3%A2-preceptor-ratios-for-practice-based-learning-across-health-disciplines-a-systematic-review
#19
Peter Loewen, Michael Legal, Allison Gamble, Kieran Shah, Stacey Tkachuk, Peter Zed
CONTEXT: Practice-based learning is a cornerstone of developing clinical and professional competence in health disciplines. Practice-based learning systems have many interacting components, but a key facet is the number of learners per preceptor. Different learner : preceptor ratios may have unique benefits and pose unique challenges for participants. This is the first comprehensive systematic review of the topic. Our research questions were: What are the benefits and challenges of each learner : preceptor ratio in practice-based learning from the perspectives of the learners, preceptors, patients and stakeholder organisations (i...
November 23, 2016: Medical Education
https://www.readbyqxmd.com/read/27879233/ashp-research-and-education-foundation-s-pharmacy-forecast-an-essential-resource-for-pharmacy-practice
#20
EDITORIAL
Stephen J Allen
No abstract text is available yet for this article.
November 22, 2016: American Journal of Health-system Pharmacy: AJHP
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