Akshay Gupta, Archana Proddutur, Yun-Juan Chang, Vidhatri Raturi, Jenieve Guevarra, Yash Shah, Fatima S Elgammal, Vijayalakshmi Santhakumar
Semilunar granule cells (SGCs) have been proposed as a morpho-functionally distinct class of hippocampal dentate projection neurons contributing to feedback inhibition and memory processing in juvenile rats. However, the structural and physiological features that can reliably classify granule cells (GCs) from SGCs through postnatal development remain unresolved. Focusing on postnatal days 11-13, 28-42, and > 120, corresponding with human infancy, adolescence, and adulthood, we examined the somato-dendritic morphology and inhibitory regulation in SGCs and GCs to determine the cell-type specific features...
December 2020: Brain Structure & Function