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Dry eye refractive surgery

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https://www.readbyqxmd.com/read/30499532/-secondary-dry-eye-syndrome-after-keratorefractive-surgeries-and-approaches-to-its-treatment-and-prevention
#1
I A Bubnova, G B Egorova, T S Mitichkina, V V Averich, E I Fettser
The article reviews the particularities of development and pathogenesis of secondary dry eye syndrome (DES) after refractive surgeries including a complex of problems related to changes in tear film content, damage of eye surface and neurotrophic epitheliopathy. Additionally, modern algorithms of treatment and prevention of secondary DES in patients after refractive surgeries are described. Despite the transient nature of the changes, excimer-laser surgery can lead to lasting deficiencies of eye surface in some patients...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/30481814/dry-eye-after-lasik
#2
Ikuko Toda
Post-LASIK dry eye is the most common postoperative dry eye after ophthalmic surgeries. The clinical signs of post-LASIK dry eye include positive vital staining of the ocular surface, decreased tear breakup time and Schirmer test values, reduced corneal sensitivity, and decreased functional visual acuity. The symptoms and signs usually last for about 1 month after LASIK. A small number of patients continue to experience symptoms more than 1 year postoperatively. It has been suggested that the loss of corneal innervation caused by flap-making is the major cause, affecting the corneal-lacrimal gland, corneal-blinking, and blinking-meibomian gland reflexes, resulting in decreased aqueous and lipid tear secretion and mucin expression...
November 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/30481803/functional-visual-acuity
#3
Minako Kaido
Dry eye (DE) causes irregularity of the ocular surface and reduces the quality of vision. An intact, regular tear film is essential for high-quality retinal images; however, visual tasks requiring sustained gazing can disrupt the tear film, eventually degrading visual function. A functional visual acuity (FVA) measurement system has been uniquely developed in Japan to evaluate visual function related to tear stability in patients with DE. FVA has been shown to correlate with optical quality. The system measures the change in visual acuity (VA) over time automatically in aqueous-deficient DE and short tear breakup tear film DE characterized by decreased tear stability and minimal epithelial damage...
November 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/30385451/the-feasibility-of-finger-prick-autologous-blood-fab-as-a-novel-treatment-for-severe-dry-eye-disease-ded-protocol-for-a-randomised-controlled-trial
#4
Shafi Balal, Arit Udoh, Yannis Pappas, Erica Cook, Garry Barton, Ali Hassan, Karen Hayden, Rupert Richard Alexander Bourne, Sajjad Ahmad, Shahina Pardhan, Michael Harrison, Benjamin Sharma, Mohammad Wasil, Anant Sharma
INTRODUCTION: Patients with severe dry eye disease (DED) often have limited treatment options with standard non-surgical management focused on the use of artificial tears for lubrication and anti-inflammatory drugs. However, artificial tears do not address the extraordinary complexity of human tears. Crudely, human tears with its vast constituents is essentially filtered blood. Blood and several blood-derived products including autologous serum, have been studied as tear substitutes. This study proposes to test the use of whole, fresh, autologous blood obtained from a finger prick for treatment of severe DED...
October 31, 2018: BMJ Open
https://www.readbyqxmd.com/read/30347561/-effect-of-different-medication-time-prior-to-corneal-refractive-surgery-on-tear-film-stability
#5
K J Chen, T Yu, J Pan, L N Liu, M Lang, J Bai
Objective: To investigate the effect of different medication time prior to corneal refractive surgery on tear film stability. Methods: Prospective cohort study. A total of 60 patients (60 eyes), including 38 males (63.3%) and 22 females (37.7%) with an average age of (24.2±5.1) years (form 18 to 37 years), who had planned for corneal refractive surgery with normal ocular surface disease index score were included in this study. The patients were divided into 1d group (medication of 1 day, 30 eyes) and 3d group (medication of 3 days, 30 eyes) randomly...
October 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/30240724/repeatability-and-reproducibility-of-corneal-epithelial-thickness-mapping-with-spectral-domain-optical-coherence-tomography-in-normal-and-diseased-cornea-eyes
#6
Ruti Sella, Linda M Zangwill, Robert N Weinreb, Natalie A Afshari
PURPOSE: To evaluate the performance of the epithelial thickness mapping (ETM) of the iVue spectral domain optical coherence tomography (SD-OCT) (Optovue Inc., Fremont, CA) in normal and diseased cornea eyes. DESIGN: Reliability and validity analysis. METHODS: Sixty eyes of 60 subjects were recruited for the study that included normal subjects (n=12) and patients with corneal diseases (12 each with dry eye syndrome (DES), contact lens (CL) wear, post laser refractive surgery (LRS), and keratoconus (KCN))...
September 18, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30228689/small-incision-lenticule-extraction-smile-the-future-of-refractive-surgery-is-here
#7
John F Doane, Jae E Cauble, Jace J Rickstrew, J Quinten Tuckfield
Small Incision Lenticule Extraction (SMILE) is a relatively new one-step refractive procedure that has recently been approved by the FDA for the treatment of myopia. It is anticipated myopic astigmatism will be FDA-approved in 2019. The SMILE procedure is shown to have similar efficacy, safety, predictability, and stability as current surgical options, such as LASIK, but has been gaining popularity due to fewer potential complications, such as dry eye incidence and greater biomechanical stability, and faster recovery time...
January 2018: Missouri Medicine
https://www.readbyqxmd.com/read/30211743/epidemiology-of-persistent-postsurgical-pain-manifesting-as-dry-eye-like-symptoms-after-cataract-surgery
#8
Ravin Sajnani, Sophia Raia, Allister Gibbons, Victoria Chang, Carol L Karp, Constantine D Sarantopoulos, Roy C Levitt, Anat Galor
PURPOSE: To evaluate the epidemiology of persistent postsurgical pain (PPP) manifesting as dry eye (DE)-like symptoms 6 months after surgery. METHODS: This single-center study included 119 individuals whose cataract surgeries were performed by a single surgeon at the Bascom Palmer Eye Institute and who agreed to participate in a phone survey 6 months after surgery. Patients were divided into 2 groups: the PPP group was defined as those with a Dry Eye Questionnaire-5 score ≥6 and without PPP as those with a Dry Eye Questionnaire-5 score <6 at 6 months after cataract surgery...
December 2018: Cornea
https://www.readbyqxmd.com/read/30170707/-smile-small-incision-lenticule-extraction-among-the-corneal-refractive-surgeries-in-2018-french-translation-of-the-article
#9
REVIEW
A Chiche, L Trinh, C Baudouin, A Denoyer
Refractive surgery is a field in constant evolution. In recent years, a new procedure has appeared under the name SMILE (Small Incision Lenticule Extraction). This technique, carried out solely with a femtosecond laser, should make it possible to better preserve corneal innervation and biomechanics. After a detailed review of the technique itself, we then focus on the scientific evidence for the safety and efficacy of SMILE and its current indications. Advantages of SMILE will be discussed in comparison to disadvantages of the conventional techniques, particularly concerning dry eye and the risk of corneal ectasia with LASIK...
September 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/30089184/topography-guided-custom-photorefractive-keratectomy-for-myopia-in-primary-eyes-with-the-wavelight-ex500-platform
#10
Fernando Faria-Correia, Sara Ribeiro, Tiago Monteiro, Bernardo T Lopes, Marcella Q Salomão, Renato Ambrósio
PURPOSE: To evaluate the outcomes after topography-guided ablation treatment (T-CAT) for the correction of myopia and myopic astigmatism with photorefractive keratectomy (PRK). METHODS: This was a retrospective, non-comparative case series study of 25 patients (40 eyes) with low to moderate myopia with or without astigmatism who underwent topography-guided custom PRK with the Wave-Light EX500 excimer laser platform (Alcon Laboratories, Inc., Fort Worth, TX). The customized treatment plan was based on Topolyzer Vario topography system (Alcon Laboratories, Inc...
August 1, 2018: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29959753/initial-single-site-surgical-experience-with-smile-a-comparison-of-results-to-fda-smile-and-the-earliest-and-latest-generation-of-lasik
#11
Majid Moshirfar, Michael S Murri, Tirth J Shah, Steven H Linn, Yasmyne Ronquillo, Orry C Birdsong, Phillips C Hoopes
INTRODUCTION: The primary objective was to show our initial surgical single-site experience with small incision lenticule extraction (SMILE) after the official enrollment in March 2017 following Food and Drug Administration (FDA) approval for simple myopia in late 2016 in the United States and, subsequently, compare our results to the earliest and most advanced generation of excimer platforms for laser-assisted in situ keratomileusis (LASIK) surgery. METHODS: This was a retrospective single-site study of 68 eyes from 35 patients who had SMILE surgery...
June 29, 2018: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/29914764/smile-small-incision-lenticule-extraction-among-the-corneal-refractive-surgeries-in-2018
#12
REVIEW
A Chiche, L Trinh, C Baudouin, A Denoyer
Refractive surgery is a field in constant evolution. In recent years, a new procedure has appeared under the name SMILE (SMall Incision Lenticule Extraction). This technique, carried out solely with a femtosecond laser, should make it possible to better preserve corneal innervation and biomechanics. After a detailed review of the technique itself, we then focus on the scientific evidence for the safety and efficacy of SMILE and its current indications. Advantages of SMILE will be discussed in comparison to the conventional techniques, particularly concerning dry eye and the risk of corneal ectasia related to LASIK...
June 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29844658/evaluation-of-femtosecond-laser-in-flap-and-cap-creation-in-corneal-refractive-surgery-for-myopia-a-3-year-follow-up
#13
Mohamed Nagy Elmohamady, Walid Abdelghaffar, Ahmed Daifalla, Tamer Salem
Purpose: To evaluate femtosecond laser in flap and cap creation, detect some corneal biomechanical changes, and evaluate dry eye after laser in situ keratomileusis (LASIK), Femto-LASIK, and small incision lenticule extraction (SMILE) with 3-year follow-up. Patients and methods: Preoperative evaluation taken: full ophthalmic examination, Pentacam, ocular response analyzer, ocular surface disease index (OSDI), and tear breakup time (TBUT). LASIK flap was created using Moria microkeratome in 30 eyes (LASIK group) and using VisuMax femtosecond laser in 38 eyes (FS-LASIK group) and SMILE was done by VisuMax in 35 eyes (SMILE group)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29782336/a-review-of-small-incision-lenticule-extraction-complications
#14
REVIEW
Ronald R Krueger, Caio S Meister
PURPOSE OF REVIEW: As a flapless procedure, SMILE brings benefits to refractive surgery, such as lower corneal biomechanical impact, less dry eye risk and less stromal bed exposure. However, the longer learning curve can be a risk factor for complications. This article aims to discuss SMILE complications and proposes a categorized analysis of occurrences, dividing into two groups: intraoperative and postoperative complications. Among intraoperative, we also suggest a subdivision between those related to the laser (lenticule construction), tissue separation (lenticule dissection) and tissue removal (lenticule extraction)...
July 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29675272/topical-osmoprotectant-for-the-management-of-postrefractive-surgery-induced-dry-eye-symptoms-a-randomised-controlled-double-blind-trial
#15
R M Hazarbassanov, N G T Queiroz-Hazarbassanov, J N Barros, J A P Gomes
Background: Dry eye disease (DED) is one of the most common complications following refractive surgery. Purpose: Evaluate the efficacy of an osmoprotective eye drop (Optive®) for the management of induced DED in refractive surgery patients. Design: Double-masked randomised controlled trial. Methods: Twenty-two refractive surgery patients oriented to apply FreshTears (FT; n = 13) or Optive (Op; n = 9), topically, QID, for 3 months...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29600182/three-year-results-of-small-incision-lenticule-extraction-and-wavefront-guided-femtosecond-laser-assisted-laser-in-situ-keratomileusis-for-correction-of-high-myopia-and-myopic-astigmatism
#16
Li-Kun Xia, Jing Ma, He-Nan Liu, Ce Shi, Qing Huang
AIM: To compare and calculate the 3-year refractive results, higher-order aberrations (HOAs), contrast sensitivity (CS) and dry eye parameters after small incision lenticule extraction (SMILE) and wavefront-guided femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for correction of high myopia and myopic astigmatism. METHODS: In this prospective, non-randomized comparative study, 78 eyes with spherical equivalent (SE) of -8.11±1.09 diopters (D) received a SMILE surgery, and 65 eyes with SE of -8...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29504953/epidemiology-of-persistent-dry-eye-like-symptoms-after-cataract-surgery
#17
Eugenia Iglesias, Ravin Sajnani, Roy C Levitt, Constantine D Sarantopoulos, Anat Galor
PURPOSE: To evaluate the frequency and risk factors for persistent postsurgical pain (PPP) after cataract surgery, defined as mild or greater dry eye (DE)-like symptoms 6 months after surgery. METHODS: This single-center study included 86 individuals who underwent cataract surgery between June and October 2016 and had DE symptom information available 6 months after surgery. Patients were divided into 2 groups: controls were defined as those without DE symptoms 6 months after surgery (defined by a Dry Eye Questionnaire 5 (DEQ5) score <6), cases were defined as those with mild or greater DE-like symptoms 6 months after surgery (DEQ5 ≥6)...
July 2018: Cornea
https://www.readbyqxmd.com/read/29283117/refractive-lenticule-extraction-small-incision-lenticule-extraction-a-new-refractive-surgery-paradigm
#18
REVIEW
Sri Ganesh, Sheetal Brar, Raghavender Reddy Arra
Small incision lenticule extraction (SMILE), a variant of refractive lenticule extraction technology is becoming increasingly popular, as a flapless and minimally invasive form of laser vision correction (LVC) for the treatment of myopia and myopic astigmatism. This review aims at summarizing the principles, surgical technique, and clinical outcomes in terms of visual and refractive results, safety, efficacy, postoperative dry eye, aberrations, and biomechanics of SMILE and its comparison with other conventional techniques of LVC, such as laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK)...
January 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29182030/biomarkers-of-ocular-surface-disease-using-impression-cytology
#19
REVIEW
Suzanne Hagan
Impression cytology (IC) is a technique which permits the retrieval of the outermost layer of ocular surface cells via the use of various types of filters. It is a minimally invasive method of evaluating human conjunctival epithelial cell morphology in the diagnosis of dry eye disease, a common and distressing disorder associated with ageing, contact lens wear, autoimmune disorders and refractive (LASIK) surgery. IC may also be utilized in the diagnosis of other ocular diseases, such as keratoconus and thyroid orbitopathy...
December 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/29102130/early-clinical-outcomes-after-small-incision-lenticule-extraction-surgery-smile
#20
Alberto Recchioni, Andreas Hartwig, Jay Dermott, Sundeep Vaswani, Jay Bhatt, Robert Morris, Clare O'Donnell
PURPOSE: Dry eye is known to impact on clinical outcomes after laser vision correction and the use of a newer 'all femtosecond laser' surgical approach may be associated with less impact on the ocular surface post-operatively. The purpose of this study was to evaluate the early clinical outcomes and tear instability after the first small incision lenticule extraction (SMILE) cases undertaken by three surgeons at a single site in the UK. METHODS: Retrospective audit...
February 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
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