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https://www.readbyqxmd.com/read/29034705/considering-the-future-direction-of-children-s-and-young-people-s-nursing
#1
Sonya Clark, Alan Glasper, Jim Richardson
Sonya Clark, Senior Lecturer in Children's Nursing at Queen's University Belfast, Emeritus Professor Alan Glasper, from the University of Southampton and Jim Richardson, Senior Lecturer in Children's Nursing at Kingston University and St George's, University of London, discuss the concerns of the academic community.
October 12, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28976902/clinical-laboratory-tests-in-some-acute-exogenous-poisonings
#2
Stoilka G Tufkova, Ivan V Yankov, Diana A Paskaleva
BACKGROUND: There is no specific toxicological screening of clinical laboratory parameters in clinical toxicology when it comes to acute exogenous poisoning. AIM: To determine routine clinical laboratory parameters and indicators for assessment of vital functions in patients with acute intoxications. MATERIALS AND METHODS: One hundred and fifty-three patients were included in the present study. They were hospitalized in the Department of Clinical Toxicology at St...
September 1, 2017: Folia Medica
https://www.readbyqxmd.com/read/28947014/characteristics-of-patients-with-increasing-copd-assessment-test-scores-within-3-years
#3
Hidehiro Irie, Shotaro Chubachi, Minako Sato, Akihiro Tsutsumi, Ichiro Nakachi, Naoki Miyao, Kazumi Nishio, Hidetoshi Nakamura, Koichiro Asano, Tomoko Betsuyaku
BACKGROUND: The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a subjective measure of quality of life. The aim of this study was to examine the characteristics of COPD patients with increasing CAT scores within 3 years. METHODS: Keio University and its affiliate hospitals conducted an observational COPD cohort study over 3 years. St. George's Respiratory Questionnaire (SGRQ) and CAT were completed at baseline and annually thereafter. Patients who had at least 3 CAT scores were included (n = 315)...
October 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28933002/mepolizumab-for-treating-severe-eosinophilic-asthma-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#4
REVIEW
Iñigo Bermejo, Matt Stevenson, Katy Cooper, Sue Harnan, Jean Hamilton, Mark Clowes, Christopher Carroll, Tim Harrison, Shironjit Saha
As part of its single technology appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited the company (GlaxoSmithKline) that manufactures mepolizumab (Nucala(®)) to submit evidence on the clinical and cost effectiveness of mepolizumab for the treatment of severe eosinophilic asthma. The School of Health and Related Research Technology Appraisal Group (ScHARR-TAG) at the University of Sheffield was commissioned to act as the independent evidence review group (ERG). The ERG produced a review of the evidence for the clinical and cost effectiveness of mepolizumab as add-on to standard of care (SoC) compared with SoC and omalizumab, based upon the company's submission to NICE...
September 20, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28928190/interdisciplinary-model-of-care-radicals-for-early-detection-and-management-of-chronic-obstructive-pulmonary-disease-copd-in-australian-primary-care-study-protocol-for-a-cluster-randomised-controlled-trial
#5
Jenifer Liang, Michael J Abramson, Nicholas Zwar, Grant Russell, Anne E Holland, Billie Bonevski, Ajay Mahal, Benjamin van Hecke, Kirsten Phillips, Paula Eustace, Eldho Paul, Kate Petrie, Sally Wilson, Johnson George
INTRODUCTION: Up to half of all smokers develop clinically significant chronic obstructive pulmonary disease (COPD). Gaps exist in the implementation and uptake of evidence-based guidelines for managing COPD in primary care. We describe the methodology of a cluster randomised controlled trial (cRCT) evaluating the efficacy and cost-effectiveness of an interdisciplinary model of care aimed at reducing the burden of smoking and COPD in Australian primary care settings. METHODS AND ANALYSIS: A cRCT is being undertaken to evaluate an interdisciplinary model of care (RADICALS - Review of Airway Dysfunction and Interdisciplinary Community-based care of Adult Long-term Smokers)...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28910351/lab-meets-real-life-a-laboratory-assessment-of-spontaneous-thought-and-its-ecological-validity
#6
Christine Kuehner, Annett Welz, Iris Reinhard, Georg W Alpers
People's minds frequently wander towards self-generated thoughts, which are unrelated to external stimuli or demands. These phenomena, referred to as "spontaneous thought" (ST) and "mind wandering" (MW), have previously been linked with both costs and benefits. Current assessments of ST and MW have predominantly been conducted in the laboratory, whereas studies on the ecological validity of such lab-related constructs and their interrelations are rare. The current study examined the stability of ST dimensions assessed in the lab and their predictive value with respect to MW, repetitive negative thought (uncontrollable rumination, RUM), and affect in daily life...
2017: PloS One
https://www.readbyqxmd.com/read/28875803/-establish-trusting-relationships
#7
(no author information available yet)
Jayne Marshall trained as a nurse at Guy's Hospital in London before starting midwifery training at King's College Hospital in 1982. She became the head of the school of midwifery at Kingston University and St George's University of London in 2014, and in July became the first professor of midwifery at the University of Leicester.
September 6, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28851252/fetal-heart-rate-changes-observed-on-the-ctg-trace-during-instrumental-vaginal-delivery
#8
Wanying Xie, Abigail Archer, Chao Li, Hongyan Cui, Edwin Chandraharan
INTRODUCTION: Instrumental vaginal delivery (IVD) helps expedite delivery during second stage of labour so as to avoid a second stage caesarean section. However, due to mechanical effects on the fetal head, vacuum and forceps may cause cardiotocograph (CTG) abnormalities due to vigal stimulation as well as increased intracranial pressure. OBJECTIVE: To determine the features observed on the CTG during IVD in term pregnancy and correlate them to perinatal outcomes...
September 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28845375/correlation-between-ki-67-index-world-health-organization-grade-and-patient-survival-in-glial-tumors-with-astrocytic-differentiation
#9
George S Stoyanov, Deyan L Dzhenkov, Martina Kitanova, Ivan S Donev, Peter Ghenev
Background Glioblastoma multiforme (GBM) is a class IV astrocytic tumor, the most malignant of the four groups of World Health Organization (WHO) tumors with astrocytic differentiation. Aim The aim of this study was to estab-lish whether a correlation exists between the Ki-67 index of tumors with astrocytic differentiation, WHO grade, and patient survival. Materials and methods A retrospective non-clinical approach to patient selection was chosen for the aim of the study. A total of 47 patients diagnosed and treated for CNS tumors with astrocytic differentiation in the St...
June 26, 2017: Curēus
https://www.readbyqxmd.com/read/28838152/etiology-of-severe-acute-watery-diarrhea-in-children-in-the-global-rotavirus-surveillance-network-using-quantitative-polymerase-chain-reaction
#10
MULTICENTER STUDY
Darwin J Operario, James A Platts-Mills, Sandrama Nadan, Nicola Page, Mapaseka Seheri, Jeffrey Mphahlele, Ira Praharaj, Gagandeep Kang, Irene T Araujo, Jose Paulo G Leite, Daniel Cowley, Sarah Thomas, Carl D Kirkwood, Francis Dennis, George Armah, Jason M Mwenda, Pushpa Ranjan Wijesinghe, Gloria Rey, Varja Grabovac, Chipo Berejena, Chibumbya J Simwaka, Jeannine Uwimana, Jeevan B Sherchand, Hlaing Myat Thu, Geethani Galagoda, Isidore J O Bonkoungou, Sheriffo Jagne, Enyonam Tsolenyanu, Amadou Diop, Christabel Enweronu-Laryea, Sam-Aliyah Borbor, Jie Liu, Timothy McMurry, Benjamin Lopman, Umesh Parashar, John Gentsch, A Duncan Steele, Adam Cohen, Fatima Serhan, Eric R Houpt
Background: The etiology of acute watery diarrhea remains poorly characterized, particularly after rotavirus vaccine introduction. Methods: We performed quantitative polymerase chain reaction for multiple enteropathogens on 878 acute watery diarrheal stools sampled from 14643 episodes captured by surveillance of children <5 years of age during 2013-2014 from 16 countries. We used previously developed models of the association between pathogen quantity and diarrhea to calculate pathogen-specific weighted attributable fractions (AFs)...
July 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28820440/medical-students-attitudes-and-beliefs-towards-psychotherapy-a-mixed-research-methods-study
#11
Costas S Constantinou, Maria Georgiou, Maria Perdikogianni
Background: Research findings suggest that attitudes towards psychotherapy predict willingness to seek therapy. However, understanding how medical students think about using and referring their patients for psychotherapy is limited. Aims: The aims of this study are to measure medical students' attitudes towards professional help seeking, and to investigate the reasons for whether or not they would refer their patients to psychotherapy in their future role as doctors. Method: The participants were 127 medical students in their first and second year of the MBBS4 programme at the Cyprus campus of St George's University of London, who completed a self-report measure of attitudes towards psychotherapy and a semi-structured interview...
August 18, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28751970/service-evaluation-of-the-implementation-of-a-digitally-enabled-care-pathway-for-the-recognition-and-management-of-acute-kidney-injury
#12
Alistair Connell, Hugh Montgomery, Stephen Morris, Claire Nightingale, Sarah Stanley, Mary Emerson, Gareth Jones, Omid Sadeghi-Alavijeh, Charles Merrick, Dominic King, Alan Karthikesalingam, Cian Hughes, Joseph Ledsam, Trevor Back, Geraint Rees, Rosalind Raine, Christopher Laing
Acute Kidney Injury (AKI), an abrupt deterioration in kidney function, is defined by changes in urine output or serum creatinine. AKI is common (affecting up to 20% of acute hospital admissions in the United Kingdom), associated with significant morbidity and mortality, and expensive (excess costs to the National Health Service in England alone may exceed £1 billion per year). NHS England has mandated the implementation of an automated algorithm to detect AKI based on changes in serum creatinine, and to alert clinicians...
2017: F1000Research
https://www.readbyqxmd.com/read/28727669/differential-pulmonary-rehabilitation-outcomes-in-patients-with-and-without-copd-role-of-gender
#13
Lam-Phuong Nguyen, Emily Beck, Katherine Cayetano, Chin-Shang Li, Kimberly Hardin
PURPOSE: Individuals with all forms of pulmonary disease are referred for pulmonary rehabilitation. This study examines pulmonary rehabilitation outcomes between individuals with chronic obstructive lung disease (COPD) and non-COPD disease and the impact of gender. METHODS: This is a retrospective study at a tertiary center. The primary endpoint was the difference in 6-min walk test distance. Secondary measurements included treadmill and NuStep minutes; biceps curls and front arm raises load; quality of life measured by the St George's Respiratory Questionnaire; and University of California San Diego-Shortness of Breath Questionnaire (UCSD-SOBQ) scores...
September 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28727274/the-effect-of-depression-and-side-effects-of-antiepileptic-drugs-on-injuries-in-patients-with-epilepsy
#14
S Gur-Ozmen, M Mula, N Agrawal, H R Cock, D Lozsadi, T J von Oertzen
BACKGROUND AND PURPOSE: People with epilepsy are at increased risk of accidents and injuries but, despite several studies on this subject, data regarding preventable causes are still contradictory. The aim of this study was to investigate the relationship between injuries, side effects of antiepileptic drugs (AEDs) and depression. METHODS: Data from a consecutive sample of adult patients with epilepsy attending the outpatient clinics at St George's University Hospital in London were included...
September 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28712689/enhancing-medical-curricula-the-role-of-a-1-day-plastic-surgery-course-as-an-educational-adjunct-for-medical-students
#15
Harry V M Spiers, Alexander Zargaran, Aasim Nisar Murtaza, Amal Thomas, Mohammed Adil A Turki, Farida Ali
INTRODUCTION: Plastic surgery is underrepresented in medical school curricula. The St George׳s Surgical Society hosted a 1-day undergraduate course in plastic surgery. Our aim was to introduce students to plastic surgery and teach basic plastic surgical skills. METHODOLOGY: The skills day consisted of lectures from consultants and a core trainee followed by registrar-taught workshops in suturing, tendon repair, and local flap design. Precourse and postcourse questionnaires assessed perceptions of plastic surgery, confidence in performing basic plastic surgical skills, and usefulness of course components...
July 13, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28562077/medical-student-perceptions-of-clinical-neurosurgery-teaching-in-an-undergraduate-medical-school-curriculum
#16
James Knight, Lauren Stroud, Thomas Geyton, Anthony Stead, Hannah R Cock
AIM: The aim of this study was to evaluate undergraduate medical student perceptions as to the value of different types of neurosurgical teaching to their general neuroscience education, delivered in the penultimate year of a U.K medical school. METHODS: We surveyed penultimate-year medical students at St George's Hospital Medical School, University of London (SGUL), who were undertaking their clinical neuroscience attachment from August 2014 to July 2015. A questionnaire comprising closed Likert scale questions and an open question inviting participants to comment freely was used to assess student perception about the value of Neurosurgical sessions within their overall neuroscience education...
May 31, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28532471/perfusion-by-arterial-spin-labelling-following-single-dose-tadalafil-in-small-vessel-disease-pastis-study-protocol-for-a-randomised-controlled-trial
#17
Mathilde M H Pauls, Natasha Clarke, Sarah Trippier, Shai Betteridge, Franklyn A Howe, Usman Khan, Christina Kruuse, Jeremy B Madigan, Barry Moynihan, Anthony C Pereira, Debbie Rolfe, Egill Rostrup, Caroline E Haig, Thomas R Barrick, Jeremy D Isaacs, Atticus H Hainsworth
BACKGROUND: Cerebral small vessel disease is a common cause of vascular cognitive impairment in older people, with no licensed treatment. Cerebral blood flow is reduced in small vessel disease. Tadalafil is a widely prescribed phosphodiesterase-5 inhibitor that increases blood flow in other vascular territories. The aim of this trial is to test the hypothesis that tadalafil increases cerebral blood flow in older people with small vessel disease. METHODS/DESIGN: Perfusion by Arterial Spin labelling following Single dose Tadalafil In Small vessel disease (PASTIS) is a phase II randomised double-blind crossover trial...
May 22, 2017: Trials
https://www.readbyqxmd.com/read/28454553/ambulatory-oxygen-in-fibrotic-lung-disease-ambox-study-protocol-for-a-randomised-controlled-trial
#18
Dina Visca, Vicky Tsipouri, Letizia Mori, Ashi Firouzi, Sharon Fleming, Morag Farquhar, Elizabeth Leung, Toby M Maher, Paul Cullinan, Nick Hopkinson, Athol U Wells, Winston Banya, Jennifer A Whitty, Huzaifa Adamali, Lisa G Spencer, Piersante Sestini, Elisabetta A Renzoni
BACKGROUND: Fibrotic interstitial lung diseases (ILDs) are chronic and often progressive conditions resulting in substantial morbidity and mortality. Shortness of breath, a symptom often linked to oxygen desaturation on exertion, is tightly linked to worsening quality of life in these patients. Although ambulatory oxygen is used empirically in their treatment, there are no ILD-specific guidelines on its use. To our knowledge, no studies are available on the effects of ambulatory oxygen on day-to-day life in patients with ILD...
April 28, 2017: Trials
https://www.readbyqxmd.com/read/28448942/assessing-knowledge-of-symptoms-and-first-aid-care-of-epilepsy-in-grenada-west-indies
#19
Sean C Cofano, Disep Ojukwu, Natasha Mozumdar, Zainab Raza, Shipra Saigal, Shashank Musku, Safwan Zar, Michael Merolla, Tuula O Jalonen
Epilepsy is a chronic neurological disorder that is increasingly prevalent in developing countries. It is critical to provide appropriate support to patients during seizures in order to prevent injuries. False beliefs regarding the etiology or pathogenesis of the epilepsy and inadequate health information may put patients with epilepsy or other seizure disorders at increased risk of injury. Our objective was to assess the level of epilepsy awareness amongst the general population in Grenada and educate the participants regarding proper first-aid measures...
May 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28384106/diagnostic-dilemmas-in-hepatitis-c-virus-infection-for-hemodialysis-patients
#20
Radka T Komitova, Maria V Atanasova, Toska A Pavlova, Monica Sh Nyagolov, Aneta V Ivanova
BACKGROUND: Hepatitis C virus (HCV) is a leading cause of chronic hepatitis in dialysis patients. The diagnosis of HCV infection in these patients is predominantly based on laboratory tests because of the specificity of the clinical course of the disease. AIM: The present prospective study aimed at determining very accurately the prevalence rate of HCV infection in patients on dialysis by simultaneously testing them for anti-HCV and for HCV RNA levels. MATERIALS AND METHODS: For the present cross-sectional longitudinal study we recruited and followed up 93 patients from St George University Hospital Hemodialysis Unit between July 2013 and December 2014...
March 1, 2017: Folia Medica
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