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internal medicine researches

Judita Kinkorová, Ondřej Topolčan
Biobanks have during last two decades gained an important role in the whole process of biomedical research and health care not only in Europe but also worldwide. Biobanks are one of the pillars in personalised medicine tackling all its aspects such as prevention, diagnosis, treatment and monitoring closely the specific characteristics of an individual patient. The current and future power of biobanks is the amount of samples of high-quality and related information available for current and future research of diseases, for optimising patients´ prevention, diagnosis, treatment and monitoring...
December 2018: EPMA Journal
Hassan Rasouli
From that time AgNPs become one of the most accessible and important antibacterial agents in our world, thousands of papers published regarding investigating all aspects of these materials. When the time elapsed and novel methods contrived to follow the fingerprint of AgNPs in the in vivo models, some critical concerns and arguments also appeared between researchers about the safety of these compounds for living cells. The paper by Dehvari and Ghahaghaei published in Volume 108 International Journal of Biological Macromolecules, pages 1128-1139 (Dehvari and Ghahghaei, 2018) suffered from some errors from safety concerns to obscurities in the results and the application of paper for applicable uses in medicine or elsewhere...
December 8, 2018: International Journal of Biological Macromolecules
Janice B Schwartz, Kenneth E Schmader, Joseph T Hanlon, Darrell R Abernethy, Shelly Gray, Jacqueline Dunbar-Jacob, Holly M Holmes, Michael D Murray, Robert Roberts, Michael Joyner, Josh Peterson, David Lindeman, Ming Tai-Seale, Laura Downey, Michael W Rich
OBJECTIVES: To identify the top priority areas for research to optimize pharmacotherapy in older adults with cardiovascular disease (CVD). DESIGN: Consensus meeting. SETTING: Multidisciplinary workshop supported by the National Institute on Aging, the American College of Cardiology, and the American Geriatrics Society, February 6-7, 2017. PARTICIPANTS: Leaders in the Cardiology and Geriatrics communities, (officers in professional societies, journal editors, clinical trialists, Division chiefs), representatives from the NIA; National Heart, Lung, and Blood Institute; Food and Drug Administration; Centers for Medicare and Medicaid Services, Alliance for Academic Internal Medicine, Patient-Centered Outcomes Research Institute, Agency for Healthcare Research and Quality, pharmaceutical industry, and trainees and early career faculty with interests in geriatric cardiology...
December 7, 2018: Journal of the American Geriatrics Society
Liliana E Ortiz-Moreira, Eduardo A Fasce-Henry, Olga B Matus-Betancourt, Ivone Campos C
Medical education in Chile has a good research productivity. National educators are skilled in complex curricular design processes and in didactic innovation. However, the question of what it means to be doctor in a society that moves towards interculturality, has not been addressed thoroughly. Using the structure of a clinical record, we outline our critical view about the relationship between medical education and diversity. To describe the medical history, we refer to some variables of the training process such as the Hegemonic Model of Medicine, the epistemological beliefs of the students, the hidden curriculum and the educational environment...
July 2018: Revista Médica de Chile
Vimal Mishra, Shin-Ping Tu, Joseph Heim, Heather Masters, Lindsey Hall, Ralph R Clark, Alan W Dow
BACKGROUND: Hospitals are complex adaptive systems within which multiple components such as patients, practitioners, facilities, and technology interact. A careful approach to optimization of this complex system is needed because any change can result in unexpected deleterious effects. One such approach is discrete event simulation, in which what-if scenarios allow researchers to predict the impact of a proposed change on the system. However, studies illustrating the application of simulation in optimization of general internal medicine (GIM) team inpatient operations are lacking...
November 28, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Ivy Muya, Joanne Garside, Marco Van-der Plas, Mohammed Ali Mohammed
Introduction: Bosasso General Hospital is located in Puntland Somalia, an area affected by prolonged civil conflict, terrorism, clan fighting and piracy. International evidence highlights that staff skills and competence may have a significant impact on patient outcomes however there has been little research on emergency education in such an austere and volatile environment. The purpose of this study therefore was to identify current practices and gaps in delivering emergency medicine education in this resource-deprived environment...
December 2018: African Journal of Emergency Medicine Revue Africaine de la Médecine D'urgence
Sheng-Yan Xi, Gerald Yosel Minuk
Traditional Chinese Medicines (TCMs) have been employed for centuries in the treatment of patients with hepatocellular carcinoma (HCC). Previous reviews of this topic have focused on certain aspects of TCM treatment rather than an overall assessment of their value and mechanisms of action. Both the Chinese and English medical literatures were reviewed to identify where TCM might be of value in the treatment of HCC and the justification for such treatment. TCM treatment corrects the "internal disequilibriums" thought to be responsible for the development, growth, and spread of the tumor...
November 27, 2018: World Journal of Hepatology
Timothy C Clapper, Joanna Lee, Jeffrey Phillips, Kapil Rajwani, Neel Naik, Kevin Ching
Background: The Team Strategies and Tools to Enhance Performance and Patient Safety (TeamSTEPPS® ) program provides a situation-monitoring tool that allows health-care professionals to perform an environmental scan. This process includes scanning the status of the patient, team members, and the environment, to ensure that patient care is progressing toward the goal. It is assumed that health-care professionals will act in a certain way by providing feedback and support based on the scan...
May 2018: Education for Health: Change in Training & Practice
Prashant Mahajan, Timothy Visclosky, Sanjeev Bhoi, Sagar Galwankar, Nathan Kuppermann, Robert Neumar
Despite the fact that emergency care can impact health of populations, the global epidemiology of emergencies in children and adults is unknown and substantial variation exists in emergency infrastructure among different nations, especially among the low and middle income countries. Various research networks which are etiology specific or subspecialty specific, including emergency care based networks have positively impacted the health of populations. However, emergency departments (ED) in low and middle income counties are underrepresented in most international networks...
November 23, 2018: American Journal of Emergency Medicine
Klaus Rose, Jane M Grant-Kels
Pediatric drug development (PDD) became an industry goal when the Food and Drug Administration (FDA) granted patent extensions. This was later expanded to obligations for pediatric studies and to the European Medicines Agency's (EMA's) strict pediatric investigation plans (PIPs). Industry now sponsors many often international studies in young patients that are difficult or impossible to recruit. PDD's intellectual foundations characterize children as "therapeutic orphans," allegedly discriminated in drug treatment and development...
December 9, 2018: Therapeutic Innovation & Regulatory Science
H Kim Lyerly, Jun Ren, Renzo Canetta, Gi Hyun Kim, Sumimasa Nagai, Tomohiro Yamaguchi, Ken Hatogai, Hiroshi Katayama, Silvy Da Rocha Dias, Daniel McManus, Kathy Soltys, Zhimin Yang, Olufumilayo Olopade, Nancy Goodman, Greg Reaman, Thomas Gross
Advances in genetic sequencing and other diagnostic technologies have enabled the use of precision medicine in clinical cancer care, as well as the development of novel therapies that are targeted to specific molecular drivers of cancer. Developing these new agents and making them accessible to patients requires global clinical studies and regulatory review and approval by different national regulatory agencies. Whereas these global trials present challenges for drug developers who conduct them and regulatory agencies who oversee them, they also raise practical issues about patients with low-frequency cancers who need these therapies...
December 2018: Journal of Global Oncology
Dawna L Cato, Kathy Walker, Deborah Aders, Fuyang Liu, Mary T McFadden
As a result of recent global health events, US health care leaders are strengthening international relationships to share best practices, health research, and support of workforce capacity. The Institute for Healthcare Improvement, the National Academies of Sciences, Engineering, and Medicine, the American Nurses Credentialing Center, and the Joint Commission International have all committed to expanding their vision and mission to improve health and health care globally. To support excellence in international health care delivery, the authors embarked on a Chief Nursing Officer (CNO) US Healthcare Immersion Program...
January 2019: Nursing Administration Quarterly
S Slipchenko, O Shyshka, S Buletsa, O Sinegubov, R Hrynko
The purpose of this study is to assess the current state of international legal regulation of cadaveric donation and determine the possibility of its further unification. Therefore, the subject of the study was the legal regulation of cadaveric donation as a certain part of medicine. In particular, the work examined the norms of international law, as well as the separate provisions of the national legislation of different countries, aimed at regulating relations in the field of cadaveric donation. Also analyzed the results of scientific research on this subject...
October 2018: Georgian Medical News
Victoria Bell, Jorge Ferrão, Lígia Pimentel, Manuela Pintado, Tito Fernandes
Changes in present-day society such as diets with more sugar, salt, and saturated fat, bad habits and unhealthy lifestyles contribute to the likelihood of the involvement of the microbiota in inflammatory diseases, which contribute to global epidemics of obesity, depression, and mental health concerns. The microbiota is presently one of the hottest areas of scientific and medical research, and exerts a marked influence on the host during homeostasis and disease. Fermented foods and beverages are generally defined as products made by microbial organisms and enzymatic conversions of major and minor food components...
December 3, 2018: Foods (Basel, Switzerland)
Lia Daniels, Vijay Daniels
Background: Achievement goal theory is consistently associated with specific cognitions, emotions, and behaviours that support learning in many domains, but has not been examined in postgraduate medical education. The purpose of this research was to examine internal medicine residents' achievement goals, and how these relate to their sense of self-efficacy, epistemic emotions, and valuing of formative compared to summative assessments. These outcomes will be important as programs transition more to competency based education that is characterized by ongoing formative assessments...
November 2018: Canadian Medical Education Journal
Emily G Lattie, Susan M Kaiser, Nameyeh Alam, Kathryn N Tomasino, Elizabeth Sargent, Caryn Kseniya Rubanovich, Hannah L Palac, David C Mohr
BACKGROUND: The ability to successfully recruit participants for electronic health (eHealth) clinical trials is largely dependent on the use of efficient and effective recruitment strategies. Determining which types of recruitment strategies to use presents a challenge for many researchers. OBJECTIVE: The aim of this study was to present an analysis of the time-efficiency and cost-effectiveness of recruitment strategies for eHealth clinical trials, and it describes a framework for cost-effective trial recruitment...
November 29, 2018: Journal of Medical Internet Research
Ho Young Kim, Ju Young Kim, Hwa Yeon Park, Ji Hye Jun, Hye Yeon Koo, In Young Cho, Jinah Han, Yuliya Pak, Hyun Jung Baek, Ju Yeon Lee, Sung Hee Chang, Jung Hun Lee, Ji Soo Choe, Sun-Kyung Yang, Kyung Chul Kim, Jeong Ha Park, Seul Ki Paik
BACKGROUND: With the significant growth of migration and expatriation, facilitated by increased global mobility, the number of Koreans living abroad as of 2016 is approximately 7.4 million (15% of the Korean population). Healthcare utilization or health problems, especially among expatriates in developing countries, have not been well researched despite the various health risks these individuals are exposed to. Consequently, we identified the health utilization patterns and healthcare needs among Korean expatriates in Vietnam, Cambodia, and Uzbekistan...
November 29, 2018: Globalization and Health
Anna G Manidaki, Ioanna Tsiligianni, Constatinos Trompoukis
The present article reports on the career of Professor Nikolaos Louros and his contribution to the development of obstetrics and gynaecology. The data presented is based on desk research with the aim to gather and analyse relevant credible information from documents existing in primary and secondary resources in the archive of Foundation History of Medicine N. Louros. As a Professor at the University of Athens, Louros introduced new teaching methods. His multifaceted work includes writing, teaching, research, and the clinical and laboratory context...
December 2018: Acta Medico-historica Adriatica: AMHA
Markus Luster, Cumali Aktolun, Isabel Amendoeira, Marcin Barczyński, Keith C Bible, Leonidas H Duntas, Rossella Elisei, Daria Handkiewicz-Junak, Martha Hoffmann, Barbara Jarzab, Laurence Leenhardt, Thomas J Musholt, Kate Newbold, Iain James Nixon, Jan Smit, Manuel Sobrinho-Simões, Julie Ann Sosa, R Michael Tuttle, Frederik Verburg, Leonard Wartofsky, Dagmar Führer-Sakel
BACKGROUND: The American Thyroid Association (ATA) Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer (DTC) are highly influential practice recommendations. The latest revision appeared in 2015 ("ATA 2015"). These guidelines were developed predominantly by North American experts. European experts frequently have different perspectives, given epidemiological, technological/methodological, practice organization, and medicolegal differences between the respective regions...
November 28, 2018: Thyroid: Official Journal of the American Thyroid Association
Ting-Ting Wang, Li-Yun He, Ming Zhang, Shao-Mo Wang, Ai-Guang Zhao, Lei Chu, Li-Yuan Zhang, Sheng-Fu You, Jie You
OBJECTIVE: To develop an improved version of the Quality-of-Life Assessment instrument for Lung Cancer Patients Based on Traditional Chinese Medicine (QLASTCM-Lu) and to evaluate its psychometric property. METHODS: The structured group method and the theory in developing rating scale were employed to revise the preliminary scale. The psychometric property (reliability, validity, and responsiveness) of the established QLASTCM-Lu (modified) were evaluated by quality of life data measured in 100 lung cancer patients...
November 27, 2018: Chinese Journal of Integrative Medicine
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