Xiangchao Luo, Qi Wang, Xuli Tang, Jixiang Xu, Mengxue Wang, Pinglin Li, Guoqiang Li
Thirteen new linear terpenes, including 11 rare acyclic manoalide derivatives ( 1 - 11 ), one polyprenylphenol derivative ( 12 ), and one polyprenylbenzaldehyde derivative ( 13 ), together with three known compounds ( 14 - 16 ) were isolated from the sponge Luffariella variabilis collected in the South China Sea. The planar structures were resolved by NMR and MS analyses, while the absolute configurations were fully elucidated by NOESY experiments, combined with experimental and calculated ECD spectra, acetal formation, empirical rules of 1 H and 13 C NMR shifts, DP4+ probability analyses, and Mosher's method...
December 28, 2020: Journal of Natural Products