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Diffuse alveolar hemorrhage

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https://www.readbyqxmd.com/read/28217966/pathogenesis-of-diffuse-alveolar-hemorrhage-in-murine-lupus
#1
Haoyang Zhuang, Shuhong Han, Pui Y Lee, Ravil Khaybullin, Stepan Shumyak, Li Lu, Amina Chatha, Anan Afaneh, Yuan Zhang, Chao Xie, Dina Nacionales, Lyle Moldawer, Xin Qi, Li-Jun Yang, Westley H Reeves
OBJECTIVE: Diffuse alveolar hemorrhage (DAH) in lupus patients is >50% fatal. The cause is unknown. The pathogenesis of DAH in C57BL/6 mice with pristane-induced lupus, a model of human lupus-associated DAH, was examined. METHODS: Clinical/pathological and immunological manifestations DAH in pristane-lupus were compared with human DAH. Tissue distribution of pristane was examined by mass spectrometry. Cell types responsible for disease were determined by in vivo depletion using clodronate liposomes (CloLip) and anti-neutrophil monoclonal antibodies (GR1)...
February 19, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28202865/repeated-diffuse-alveolar-hemorrhage-in-a-patient-with-hemophilia-b
#2
Hajime Kasai, Jiro Terada, Hiromasa Hoshi, Takashi Urushibara, Fumiaki Kato, Rintaro Nishimura, Koichiro Tatsumi
Diffuse alveolar hemorrhage (DAH) is a life-threatening complication that occurs in association with various diseases including coagulation disorders. In rare cases, it is caused by hemophilia. A 48-year-old man was admitted to our hospital for a third time due to DAH. Although the cause of DAH could not be identified by bronchoscopy or laboratory tests, a good response to corticosteroids suggested idiopathic DAH with pulmonary capillaritis. The patient was diagnosed with hemophilia B based on the results of a detailed inquiry, a mildly prolonged activated partial thromboplastin time, and low factor IX activity...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28138763/-haemoptysis-intensive-care-management-of-pulmonary-hemorrhage
#3
J H Ficker, W M Brückl, J Suc, A Geise
There is a wide spectrum of severities in patients with pulmonary bleeding with a range from mild haemoptysis to severe bleeding with an acute risk of asphyxiation. For the management of acute pulmonary haemorrhage, it is essential to identify the underlying cause in order to initiate a target-oriented or causal therapy. The most common causes of localized pulmonary bleeding are lung cancer as well as infections, anticoagulant therapy or bronchiectasis. Diffuse alveolar haemorrhage is mostly due to pulmonary vasculitis or connective tissue disease, but may also occur in pulmonary metastasis, congestive heart failure, coagulation disorders and from many other causes...
January 30, 2017: Der Internist
https://www.readbyqxmd.com/read/28050000/the-effects-of-plasma-exchange-on-severe-vasculitis-with-diffuse-alveolar-hemorrhage
#4
Kimihiko Goto, Kentaro Nakai, Hideki Fujii, Shinichi Nishi
Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis is a life-threatening disease characterized by rapidly progressive glomerulonephritis (RPGN) and diffuse alveolar hemorrhage (DAH). Glucocorticoids and immunosuppressants are commonly used to treat this disease but may induce irreversible side effects, particularly in elderly patients. We herein report the case of a 76-year-old woman with RPGN. After methylprednisolone pulse therapy, DAH occurred, and she required ventilatory support. After plasma exchange, her serum creatinine level improved, and she was discharged with home oxygen therapy...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28027784/analysis-of-three-cases-of-diffuse-alveolar-hemorrhage-false-negative-results-in-pulmonary-ultrasound
#5
L A Gorordo Delsol, A Jiménez Ruiz, G D Hernández López
No abstract text is available yet for this article.
December 24, 2016: Medicina Intensiva
https://www.readbyqxmd.com/read/27994935/diffuse-alveolar-hemorrhage-after-clopidogrel-use
#6
Tolga Onuk, Göktürk İpek, Mehmet Baran Karataş, Recep Hacı, Neşe Çam
No abstract text is available yet for this article.
November 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27981314/severe-alveolar-hemorrhage-what-s-in-it-for-the-gastroenterologist
#7
Alina Popp, Ciprian Jurcuţ, Daniel Vasile Balaban, Mihai Șotcan, Kaija Laurila, Mariana Jinga
BACKGROUND: Alveolar hemorrhage is a potentially life-threatening condition which is usually managed by the pulmonologist. When considering its etiology, there is a rare association that sets the disease into the hands of the gastroenterologist. CASE PRESENTATION: We report the case of a 48 year-old female who was admitted to the intensive care unit for severe anemia and hemoptysis. On imaging, diffuse pulmonary infiltrates suggestive of alveolar hemorrhage were detected and a diagnosis of pulmonary hemosiderosis was made...
December 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/27918350/a-case-of-idiopathic-pulmonary-hemosiderosis-presenting-with-signs-and-symptoms-mimicking-hemolytic-anemia
#8
Dilek Doğruel, Ayşe Erbay, Nalan Yazici, Alev Arslan, Bermal Hasbay Biçen
Idiopathic pulmonary hemosiderosis is primarily a disorder of childhood, which is characterized by hemoptysis, iron deficiency anemia, and diffuse parenchymal infiltrates on chest x-ray secondary to recurrent attacks of alveolar hemorrhage. It can be diagnosed by showing hemosiderin laden macrophages in bronchoalveolar lavage fluid after other specific causes of diffuse alveolar hemorrhage are definitely excluded. A 5-year-old male patient was admitted to our clinic with sudden-onset pallor during iron therapy given for anemia...
January 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/27895951/persistent-tachypnea-and-alveolar-hemorrhage-in-an-infant-an-unexpected-etiology
#9
John Bishara, Angela Webb, Christina Valsamis, Claudia Halaby, Melodi Pirzada
Persistent tachypnea and failure to thrive during infancy have a broad differential diagnosis which includes pulmonary and cardiovascular disorders. Diffuse alveolar hemorrhage (DAH) is a rare entity in children. DAH requires an extensive work-up as certain conditions may need chronic therapy. Cardiovascular disorders are included in the etiology of DAH. We present a case of an 8-month-old female with a moderate, restrictive patent ductus arteriosus (PDA) admitted to the hospital with respiratory distress and failure to thrive...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/27872805/sevoflurane-induced-diffuse-alveolar-hemorrhage-in-a-young-patient
#10
Adam Austin, Aakash Modi, Marc A Judson, Amit Chopra
We report a very rare case of Sevoflurane Induced Diffuse Alveolar Hemorrhage in a previously healthy young adult in the post-operative period following general anesthesia. Diffuse alveolar hemorrhage (DAH) associated with inhalation injury from halogenated gases is a unique entity in the literature that practicing clinicians should be cognizant of and considered in post-operative cases of acute respiratory distress whereby other etiologies have been excluded.
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27872767/diffuse-alveolar-hemorrhage-associated-with-edoxaban-therapy
#11
Kenichi Nitta, Hiroshi Imamura, Akihiro Yashio, Satoko Kashima, Katsunori Mochizuki
Introduction. The main adverse effect of anticoagulant therapy is bleeding, and major bleeding, including intracranial, gastrointestinal, and retroperitoneal bleeding, has been reported as an adverse effect of edoxaban, a direct oral anticoagulant (DOAC). Bleeding during systemic anticoagulation with edoxaban presents a therapeutic conundrum, because there is currently no safe or efficacious reversal agent to stop major bleeding. Case Report. A 51-year-old woman had multiple traumatic injuries, including lower limb fractures...
2016: Case Reports in Critical Care
https://www.readbyqxmd.com/read/27867668/a-rare-clinical-course-of-seronegative-pulmonary-renal-syndrome
#12
M Fröhlich-Gildhoff, W J Jabs, C Berhold, M K Kuhlmann, U Ketterer, S Kische, H Ince
Purpose. Pulmonary-renal syndrome (PRS) is characterized by diffuse alveolar hemorrhage and rapidly progressive glomerulonephritis mainly due to autoimmune etiologies. Seronegative PRS is a challenging entity to the clinician, since early diagnosis may be missed leading to delayed appropriate treatment. Materials and Methods. We present the clinical course of a 77-year-old patient who was admitted under the suspected diagnosis of pneumogenic sepsis and septic renal failure with fever, dyspnea, and elevated CRP levels...
2016: Case Reports in Critical Care
https://www.readbyqxmd.com/read/27853076/diffuse-alveolar-hemorrhage-associated-with-makyo-kanseki-to-administration
#13
Yuko Iida, Yuki Takano, Yusaku Ishiwatari, Akiko Yoshida, Tetsuo Shimizu, Reiko Ito, Tomohiro Hattori, Noriaki Takahashi, Shu Hashimoto
We herein describe the first known case of diffuse alveolar hemorrhage (DAH) associated with the administration of Makyo-kanseki-to, a Chinese herbal drug. A 64-year-old man with bronchial asthma presented with persistent cough. Makyo-kanseki-to was prescribed as an adjunctive treatment for bronchial asthma. Immediately after drug ingestion, the patient expectorated bloody sputum. DAH was diagnosed based on the presence of bilateral ground-glass opacity which was identified on chest computed tomography and bloody bronchoalveolar lavage fluid...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27851549/1914-synthetic-cathinone-inhalation-resulting-in-diffuse-alveolar-hemorrhage
#14
Masakazu Nitta, Natsuo Kamimura, Hiroshi Endoh
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851546/1911-tele-icu-regionalization-of-critical-care-and-ecmo-leptospirosis-with-diffuse-alveolar-hemorrhage
#15
Ali Tabatabai, Michael Mazzeffi, Ann Matta, Allison Hollis, Marc Zubrow, Keshava Rajagopal, Sarah Schmalze, Thomas Scalea
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851534/1899-a-rare-case-of-cannabis-induced-diffuse-alveolar-hemorrhage
#16
Umair Tariq, Hermes Velasquez
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851530/1895-rituximab-therapy-in-refractory-diffuse-alveolar-hemorrhage-associated-with-anca-vasculitis
#17
Sahil Pandya, Mona Vashi, Robert Balk
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851519/1884-unusual-case-of-collagen-vascular-disease-induced-diffuse-alveolar-hemorrhage-requiring-ecmo
#18
Zachary Gales, Ryan Hoecker, Ricardo Restrepo, Christina Heindel, Karel Calero, Robert Hooker
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851400/1765-strongyloides-an-unusual-cause-of-diffuse-alveolar-hemorrhage-in-an-immunocompromised-host
#19
Shyam Kapadia, William Mazalewski, Chakrapol Sriaroon, Ricardo Restrepo
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27843786/diffuse-alveolar-hemorrhage-in-patients-undergoing-neurointervention-a-case-report
#20
Yun Suk Choe, Na Young Kim, Ae Ryoung Lee
INTRODUCTION: Diffuse alveolar hemorrhage (DAH) is a very rare complication but acute and life-threatening event. Clopidogrel has generally administered for neurointerventional surgery, but there were no reports of DAH related to clopidogrel in patients undergoing neurointervention. CASE PRESENTATION: A 70-year-old male presented with DAH associated with clopidogrel after transfemoral cerebral angiography and coil embolization for cerebral aneurysm. The chest radiography showed bilateral symmetric peribronchial consolidation and bronchoscopy revealed diffuse hemorrhage on the bronchial wall at the bilateral lung...
October 2016: Anesthesiology and Pain Medicine
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