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https://www.readbyqxmd.com/read/28538830/subjective-memory-complaints-and-their-relation-with-verbal-fluency-in-active-older-people
#1
Flavia Rodrigues Bernardes, Camila Kretzer Machado, Monique Coan Souza, Marcos José Machado, Aline Megumi Arakawa Belaunde
Purpose: To verify subjective memory complaints and their relation to verbal fluency in older people participating in community groups. Methods: An epidemiological quantitative study performed in community groups for older people in Florianópolis, state of Santa Catarina, Brazil. Data were collected by structured interview using the Memory Complaint Questionnaire (MAC-Q) and the Verbal Fluency Test (VFT) by semantic categories "animals/minute". For an inferential descriptive analysis, data with p < 5% were considered...
May 22, 2017: CoDAS
https://www.readbyqxmd.com/read/28538627/early-heparin-administration-after-tbi-prolonged-cognitive-recovery-associated-with-reduced-cerebral-edema-and-neutrophil-sequestration
#2
Katsuhiro Nagata, Kevin D Browne, Yujin Suto, Kenichiro Kumasaka, John Cognetti, Victoria E Johnson, Joshua Marks, Douglas H Smith, Jose L Pascual
BACKGROUND: Early administration of unfractionated heparin (UFH) after TBI reduces early in vivo circulating leukocytes (LEU) in peri-injury penumbral brain tissue, enhancing cognitive recovery 2 days after injury. It remains unclear how long this effect lasts and if this is related to persistently accumulating LEU in penumbral brain tissue. We hypothesized that UFH reduces LEU brain tissue sequestration resulting in prolonged cognitive recovery. METHODS: CD1 male mice underwent either TBI by controlled cortical impact (CCI) or sham craniotomy...
May 22, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28538520/radiation-induced-cerebellar-cerebral-functional-connectivity-alterations-in-nasopharyngeal-carcinoma-patients
#3
Qiongmin Ma, Ling-Li Zeng, Jian Qin, Zhiguo Luo, Jianpo Su, Donglin Wu, Shijun Qiu, Dewen Hu
The current study aimed to investigate the altered cerebellar-cerebral functional connectivity (FC) induced by radiotherapy to nasopharyngeal carcinoma (NPC) patients. Twenty-four NPC patients without treatment, and 35 NPC patients receiving radiotherapy underwent functional MRI scanning. Montreal cognitive assessment (MoCA) was performed to evaluate the cognitive status of all participants. FC between 10 predefined cerebellar seeds, which were demonstrated to be involved in different brain functional networks, and all brain voxels was obtained for each participant...
May 19, 2017: Neuroreport
https://www.readbyqxmd.com/read/28538227/self-directedness-predicts-quality-of-life-in-individuals-with-psychotic-experiences-a-1-year-follow-up-study
#4
Letícia Oliveira Alminhana, Miguel Farias, Gordon Claridge, C Robert Cloninger, Alexander Moreira-Almeida
There is a high prevalence of psychotic-like experiences in nonclinical patient cohorts from Brazil. This study aimed to test whether personality dimensions, as well as schizotypy, are important predictors of quality of life (QoL) in individuals with psychotic experiences (PE). METHOD: 115 participants were recruited from Spiritist Centers in Brazil. At the 1-year follow up, 90 participants (78%) were reassessed. Instruments were the SCID-I (Structured Clinical Interview for DSM-IV), TCI-R 140 (Revised Temperament and Character Inventory), OLIFE-R (Oxford-Liverpool Inventory of Feelings and Experiences), and WHOQOL-BREF (World Health Organization QoL Instrument)...
May 25, 2017: Psychopathology
https://www.readbyqxmd.com/read/28538226/exploring-neural-efficiency-in-multiple-sclerosis-patients-during-the-symbol-digit-modalities-test-a-functional-magnetic-resonance-imaging-study
#5
María Sol Fittipaldi-Márquez, Álvaro Javier Cruz-Gómez, Carla Sanchis-Segura, Antonio Belenguer, César Ávila, Cristina Forn
BACKGROUND: Reduced information-processing speed (IPS) is a primary cognitive deficit of multiple sclerosis (MS) patients. The neural efficiency hypothesis describes an inverse relationship between cognitive performance in a task and the amount of cognitive resources devoted to it. Previous studies have shown that the neural efficiency hypothesis provides an appropriate framework to explore cognitive dysfunction in neurological patients. OBJECTIVE: The aim of this study was to explore the neural efficiency hypothesis regarding IPS capabilities in cognitively preserved MS patients...
May 25, 2017: Neuro-degenerative Diseases
https://www.readbyqxmd.com/read/28538108/moderate-to-vigorous-physical-activity-executive-functions-and-prefrontal-brain-oxygenation-in-children-a-functional-near-infrared-spectroscopy-study
#6
Manuel Mücke, Christian Andrä, Markus Gerber, Uwe Pühse, Sebastian Ludyga
Despite accumulating evidence that regular exercise improves executive functioning, the underlying neurophysiological mechanisms have rarely been investigated. The present study aimed to compare cognitive performance as well as task-specific concentration changes in oxygenated haemoglobin in the prefrontal cortex between children with higher and lower moderate-to-vigorous physical activity (MVPA). Physical activity was measured over 7 consecutive days using actigraphy. Afterwards, participants (N = 50) completed verbal fluency tests (VFTs) and mental arithmetic (MA) for the assessment of cognitive flexibility and working memory capacity...
May 24, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28538088/effects-of-the-insulin-sensitizer-metformin-in-alzheimer-disease-pilot-data-from-a-randomized-placebo-controlled-crossover-study
#7
Aaron M Koenig, Dawn Mechanic-Hamilton, Sharon X Xie, Martha F Combs, Anne R Cappola, Long Xie, John A Detre, David A Wolk, Steven E Arnold
Epidemiological studies have identified a robust association between type II diabetes mellitus and Alzheimer disease (AD), and neurobiological studies have suggested the presence of central nervous system insulin resistance in individuals with AD. Given this association, we hypothesized that the central nervous system-penetrant insulin-sensitizing medication metformin would be beneficial as a disease-modifying and/or symptomatic therapy for AD, and conducted a placebo-controlled crossover study of its effects on cerebrospinal fluid (CSF), neuroimaging, and cognitive biomarkers...
April 2017: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/28538087/total-brain-and-hippocampal-volumes-and-cognition-in-older-american-indians-the-strong-heart-study
#8
Brenna Cholerton, Adam Omidpanah, Tara M Madhyastha, Thomas J Grabowski, Astrid M Suchy-Dicey, Dean K Shibata, Lonnie A Nelson, Steven P Verney, Barbara V Howard, William T Longstreth, Thomas J Montine, Dedra Buchwald
BACKGROUND: Estimates of hippocampal volume by magnetic resonance imaging have clinical and cognitive correlations and can assist in early Alzheimer disease diagnosis. However, little is known about the relationship between global or regional brain volumes and cognitive test performance in American Indians. MATERIALS AND METHODS: American Indian participants (N=698; median age, 72 y) recruited for the Cerebrovascular Disease and its Consequences in American Indians study, an ancillary study of the Strong Heart Study cohort, were enrolled...
April 2017: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/28538047/auditory-processing-disorder-what-does-it-mean-and-what-can-be-done
#9
Krista Bartlett, Elissa Kelley, Julie Purdy, Martin T Stein
Julian, an 11-year-old boy in the sixth grade with a compliant disposition and a positive attitude, has had a significant decline in his academic performance over the last 2 years. He spends much of his time in the nurse's office with headaches and fatigue. He reports that he cannot concentrate or follow along in class. Vision and hearing screenings were normal.Julian's teachers report that although he has no behavior problem, he is inattentive and does not put forth the effort she feels he is capable of giving...
May 22, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28538042/counterbalanced-comparison-of-the-bsid-ii-and-bayley-iii-at-eighteen-to-twenty-two-months-corrected-age
#10
Meghan Sharp, Sara B DeMauro
OBJECTIVE: To evaluate differences in developmental assessments using the current version of the Bayley Scales of Infant Development (Bayley-III) as compared to the older BSID-II. Previous studies suggest that average scores on the Bayley-III may be significantly higher than scores on the previous version, but the magnitude and potential impact of differences between these 2 assessments are uncertain. METHODS: We enrolled 77 former preterm infants (born <32 wk gestation and ≤2000 g) at 18 to 22 months corrected age in this randomized crossover study...
May 19, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28535638/-application-of-long-term-video-electroencephalogram-and-resting-state-functional-magnetic-resonance-imaging-in-detection-of-cognition-in-patients-with-benign-epilepsy-of-childhood-with-centrotemporal-spikes
#11
X X Yan, Q Yu, Y T Gao, L T Li, D H Yu, Y Chen, X J Yao, W D Yang, Z J Chen, J Z Yin, Y An, K Tan
Objective: To study the relationship between the changes of brain network and cognition in patients with benign epilepsy of childhood with centrotemporal spikes (BECTS) by using long term video electroencephalogram (VEEG) and resting-state functional magnetic resonance imaging (RS-fMRI) technology. Methods: Eleven patients with right-handed were recruited (from April 2015 to September 2016) from epilepsy specialist outpatients and functional department of neurosurgery of Tianjin Medical University General Hospital...
May 23, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28535408/differences-in-clinical-and-cognitive-variables-in-seasonal-affective-disorder-compared-to-depressive-related-disorders-evidence-from-a-population-based-study-in-finland
#12
I Morales-Muñoz, S Koskinen, T Partonen
BACKGROUND: Seasonal affective disorder (SAD) is a type of depression with seasonal pattern. Although it involves some idiosyncratic symptoms, it can overlap with other depressive disorders such as major depressive disorder (MDD) or dysthymia. We aimed to characterize the differences in specific cognitive and clinical symptoms between SAD and depressive-related disorders. METHODS: In total, 4554 Finnish subjects from the population-based Health 2011 Survey were interviewed with the Munich version of Composite International Diagnostic Interview (M-CIDI) and filled in the Seasonal Pattern Assessment Questionnaire (SPAQ)...
March 28, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28535277/sensory-impairments-and-cognitive-function-in-middle-aged-adults
#13
Carla R Schubert, Karen J Cruickshanks, Mary E Fischer, Yanjun Chen, Barbara E K Klein, Ronald Klein, A Alex Pinto
Background: Hearing, visual, and olfactory impairments have been associated with cognitive impairment in older adults but less is known about associations with cognitive function in middle-aged adults. Methods: Sensory and cognitive functions were measured on participants in the baseline examination (2005-2008) of the Beaver Dam Offspring Study. Cognitive function was measured with the Trail Making tests A (TMTA) and B (TMTB) and the Grooved Peg Board test. Pure-tone audiometry, Pelli-Robson letter charts, and the San Diego Odor Identification test were used to measure hearing, contrast sensitivity, and olfaction, respectively...
May 23, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28535111/relative-validity-and-reproducibility-of-an-interviewer-administered-14-item-ffq-to-estimate-flavonoid-intake-among-older-adults-with-mild-moderate-dementia
#14
Katherine Kent, Karen Charlton
There is a large burden on researchers and participants when attempting to accurately measure dietary flavonoid intake using dietary assessment. Minimizing participant and researcher burden when collecting dietary data may improve the validity of the results, especially in older adults with cognitive impairment. A short 14-item food frequency questionnaire (FFQ) to measure flavonoid intake, and flavonoid subclasses (anthocyanins, flavan-3-ols, flavones, flavonols, and flavanones) was developed and assessed for validity and reproducibility against a 24-hour recall...
May 23, 2017: Journal of Nutrition in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28535099/do-sideline-concussion-assessments-predict-subsequent-neurocognitive-impairment-after-sport-related-concussion
#15
Alicia Sufrinko, Jamie McAllister-Deitrick, Melissa Womble, Anthony Kontos
CONTEXT:   Comprehensive, multi-domain assessment is the standard of care after sport-related concussion. However, the relationship between performance on sideline concussion-assessment tools and in-office computerized neurocognitive testing has received little attention, and the prognostic utility of sideline measures is unknown. OBJECTIVE:   To evaluate concurrent impairment on commonly used concussion measures 24 to 48 hours postinjury while also determining the predictive utility of sideline measures on computerized neurocognitive testing in the acute to subacute recovery periods postinjury...
May 23, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28535073/paced-auditory-serial-addition-test-pasat-3-0%C3%A2-s-demographically-corrected-norms-for-the-portuguese-population
#16
Claudia Sofia Sousa, Mariana Rigueiro Neves, Ana Margarida Passos, Aristides Ferreira, Maria José Sá
The main goal of this study was to produce adjusted normative data for the Portuguese population on the Paced Auditory Serial Addition Test (PASAT 3.0 s), the version used in the Brief Repeatable Battery of Neuropsychological Tests developed by the National Multiple Sclerosis Society. The study included 326 community-dwelling individuals (199 women and 127 men) aged between 20 and 70 (mean = 40.33, SD = 14.40), who had educational backgrounds ranging from 4 to 23 years of schooling (mean = 12...
May 23, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28534935/effect-of-fasudil-on-cognitive-function-following-status-convulsion-in-rats
#17
Rong He, Wei Han, Xiaojie Song, Xiaoju Tang, Li Cheng, Li Jiang
Fasudil has been demonstrated to possess a protective effect in neural injury; however, its protective effect on convulsive brain injury remains to be assessed. The aim of the present study was to investigate the latent mechanism and effect of fasudil on cognitive function following status convulsion (SC) in rats. Initially, to determine the effects of SC, the expression levels of Ras homolog gene family, member A (RhoA)/Rho‑associated protein kinase (ROCK) signaling pathway‑associated proteins were measured by western blot analysis in 16 rats...
May 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28534798/alzheimer-s-disease-diagnosis-using-landmark-based-features-from-longitudinal-structural-mr-images
#18
Jun Zhang, Mingxia Liu, Le An, Yaozong Gao, Dinggang Shen
Structural magnetic resonance imaging (MRI) has been proven to be an effective tool for Alzheimer's disease (AD) diagnosis. While conventional MRI-based AD diagnosis typically uses images acquired at a single time point, a longitudinal study is more sensitive in detecting early pathological changes of AD, making it more favorable for accurate diagnosis. In general, there are two challenges faced in MRI-based diagnosis. First, extracting features from structural MR images requires timeconsuming nonlinear registration and tissue segmentation, whereas the longitudinal study with involvement of more scans further exacerbates the computational costs...
May 16, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28534796/predicting-progression-from-mild-cognitive-impairment-to-alzheimer-s-disease-using-autoregressive-modelling-of-longitudinal-and-multimodal-biomarkers
#19
Sidra Minhas, Aasia Khanum, Farhan Riaz, Shoab Khan, Atif Alvi
Mild Cognitive Impairment is a preclinical stage of Alzheimer's disease (AD). For effective treatment of AD, it is important to identify MCI patients who are at a high risk of developing AD over the course of time. İn this study, autoregressive modelling of multiple heterogeneous predictors of Alzheimer's dısease is performed to capture their evolution over time. The models are trained using three different arrangements of longitudinal data. These models are then used to estimate future biomarker readings of individual test subjects...
May 16, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28534735/the-use-of-the-gaps-in-noise-test-as-an-index-of-the-enhanced-left-temporal-cortical-thinning-associated-with-the-transition-between-mild-cognitive-impairment-and-alzheimer-s-disease
#20
Vasiliki Vivian Iliadou, Doris-Eva Bamiou, Christos Sidiras, Nikolaos P Moschopoulos, Magda Tsolaki, Ioannis Nimatoudis, Gail D Chermak
BACKGROUND: The known link between auditory perception and cognition is often overlooked when testing for cognition. PURPOSE: To evaluate auditory perception in a group of older adults diagnosed with mild cognitive impairment (MCI). RESEARCH DESIGN: A cross-sectional study of auditory perception. STUDY SAMPLE: Adults with MCI and adults with no documented cognitive issues and matched hearing sensitivity and age. DATA COLLECTION: Auditory perception was evaluated in both groups, assessing for hearing sensitivity, speech in babble (SinB), and temporal resolution...
May 2017: Journal of the American Academy of Audiology
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