Jian Deng, Bao-Zhong Zhang, Hin Chu, Xiao-Lei Wang, Yixin Wang, Hua-Rui Gong, Renhao Li, Dong Yang, Cun Li, Ying Dou, Peng Gao, Jian-Piao Cai, Meilin Jin, Qian Du, Jasper Fuk-Woo Chan, Richard Yi-Tsun Kao, Kwok-Yung Yuen, Jian-Dong Huang
BACKGROUND: Staphylococcus aureus is a common human pathogen capable of causing diverse illnesses with possible recurrent infections. Although recent studies have highlighted the role of cellular immunity in recurrent infections, the mechanism by which S. aureus evades host responses remains largely unexplored. METHODS: This study utilizes in vitro and in vivo infection experiments to investigate difference of pro-inflammatory responses and subsequent adaptive immune responses between adsA mutant and WT S...
August 2021: EBioMedicine