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SEP or micropeptides

Ezgi Atik, Hande Gorucu-Coskuner, Tulin Taner
OBJECTIVE: The aim was to compare the clinical performance of uncoated and adhesive precoated brackets bonded with either self-etching primer (SEP) or conventional two-step etch and primer method (CEM). SUBJECTS AND METHODS: The sample consisted of 63 patients with a mean age of 15.20 ± 1.6 years. In group I (n = 15), uncoated brackets and CEM; in group II (n = 16), precoated brackets and CEM; in group III (n = 16), uncoated brackets and SEP; in group IV (n = 16), precoated brackets and SEP were used for bonding...
November 30, 2018: Clinical Oral Investigations
Seth R Bauer, Judith A Gonet, Rebecca F Rosario, Lori A Griffiths, Tracy Kingery, Anita J Reddy
BACKGROUND: The Early Management Bundle, Severe Sepsis/Septic Shock (SEP-1) quality measure is complex to abstract, which may lead to discrepancies between abstractors. This study was designed to evaluate inter-rater agreement between abstractors at individual hospitals in a health system and a lead abstractor on abstraction elements and measure compliance for SEP-1. METHODS: Patient cases qualifying for abstraction for SEP-1 over a four-month period in 2016 were initially abstracted at a local hospital and then centrally by a lead abstractor...
November 29, 2018: Joint Commission Journal on Quality and Patient Safety
Christine L Baker, Amol D Dhamane, Jack Mardekian, Oluwaseyi Dina, Cristina Russ, Lisa Rosenblatt, Melissa Lingohr-Smith, Brandy Menges, Jay Lin, Anagha Nadkarni
INTRODUCTION: Continuous usage of direct oral anticoagulants (DOACs) among nonvalvular atrial fibrillation (NVAF) patients is essential to maintain stroke prevention. We examined switching and discontinuation rates for the three most frequently initiated DOACs in NVAF patients in the USA. METHODS: Patients who initiated apixaban, rivaroxaban, or dabigatran (index event/date) were identified from the Pharmetrics Plus claims database (Jan 1, 2013-Sep 30, 2016, includes patients with commercial and Medicare coverage) and grouped into cohorts by index DOAC...
November 29, 2018: Advances in Therapy
Sreenath Madathil, Christine Blaser, Belinda Nicolau, Hugues Richard, Marie-Élise Parent
Background: Previous studies on socioeconomic position (SEP) and risk of prostate cancer (PCa) have produced contradictory results. Most measured SEP only once during the individuals' life span. The aim of the study was to identify life course models that describe best the relationship between SEP measured during childhood/adolescence, early- and late-adulthood, and risk of PCa overall as well as according to tumor aggressiveness at diagnosis. Methods: We used data from a population-based case-control study of PCa conducted in the predominantly French-speaking population in Montreal, Canada...
2018: Frontiers in Oncology
Margaret B Greenwood-Ericksen, Craig Rothenberg, Nicholas Mohr, Shawn D Andrea, Todd Slesinger, Tiffany Osborn, Jessica Whittle, Pawan Goyal, Nalani Tarrant, Jeremiah D Schuur, Donald M Yealy, Arjun Venkatesh
PURPOSE: The Centers for Medicare and Medicaid Services (CMS) and the American College of Emergency Physicians (ACEP) developed national quality measures for emergency department (ED) sepsis care. Like care for many conditions, meeting sepsis quality metrics can vary between settings. We sought to examine and compare sepsis care quality in rural vs urban hospital-based EDs. METHODS: We analyzed data from EDs participating in the national Emergency Quality Network (E-QUAL)...
November 28, 2018: Journal of Rural Health
Jaakko Anttila, Mimmi Tolvanen, Rami Kankaanpää, Satu Lahti
AIMS: In 2007, Finnish authorities gave a national recommendation that schools should not sell sweet products. This study aimed to determine the effects of the national recommendation on school-level intermediary determinants (factors related to oral health inequalities) and if the changes were different according to school-level socio-economic position (SEP). METHODS: This ecological and longitudinal study combined school-level data from two independent studies from Finnish upper comprehensive schools ( N = 970): the School Health Promotion study (SHPS) and the School Sweet Selling survey (SSSS)...
November 29, 2018: Scandinavian Journal of Public Health
Giuseppe Ciconte, Žarko Ćalović, Luke C McSpadden, Kyungmoo Ryu, Jan Mangual, Igor Caporaso, Mario Baldi, Massimo Saviano, Amarild Cuko, Raffaele Vitale, Manuel Conti, Luigi Giannelli, Gabriele Vicedomini, Vincenzo Santinelli, Carlo Pappone
PURPOSE: Cardiac resynchronization therapy (CRT) with multipoint left ventricular (LV) pacing (MultiPoint™ Pacing [MPP]) improves long-term LV reverse remodeling, though questions persist about how to program LV pacing vectors and delays. We evaluated if an empirical method of programming MPP vectors and delays between pacing pulses improved CRT response similar to pressure-volume loop (PVL) optimized MPP programming. METHODS: Patients undergoing CRT implant (Quadra Assura MP™ CRT-D and Quartet™ LV lead) received MPP with programmed settings optimized either by PVL measurements at implant (PVL-OPT group) or empirically determined by maximizing the spatial separation between the two cathodes and minimal delays between the three ventricular pacing pulses (MAX-SEP group)...
November 27, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Snaha Sanghvi, Mikhail Podlog, Ryan D Aycock
No abstract text is available yet for this article.
October 25, 2018: Annals of Emergency Medicine
Akihiro Higuchi
Dry eye syndrome is a multifactorial condition on the tear and ocular surface. Autologous serum eye drop is an effective method for treating dry eye. Autologous serum eye drops are now widely used by specialists since a first report in 1975. The results of a systematic study showed that the efficacy of autologous serum eye drops remains ambiguous because its preparation methods and clinical application have not been standardized. To elucidate the efficacy of autologous serum eye drops, well-designed, large-scale, high-quality randomized controlled trials need to be conducted with standardized treatment and use...
November 1, 2018: Investigative Ophthalmology & Visual Science
Behzad Eyvazi, Ahmad Jamshidi-Zanjani, Ahmad Khodadadi Darban
Nano-magnetic MnFe2 O4 was prepared and examined to immobilize Cr(VI) in the soil. According to the results of scanning electron microscopy (SEM) and X-ray diffraction (XRD) the formation of nano-magnetic MnFe2 O4 with the particle size of less than 200 nm was demonstrated. Compared with the untreated soil, the leachability of Cr(VI) was reduced from 70.95% to 4.22% through toxicity characteristic leaching procedure (TCLP) at a dosage of 2 g/L of nanoparticles and 192 h remediation time. At the same condition, the physiologically based extraction test (PBET) human bioaccessibility of chromium was reduced from 86...
November 12, 2018: Journal of Hazardous Materials
D B MacDonald, C Dong, R Quatrale, F Sala, S Skinner, F Soto, A Szelényi
Intraoperative somatosensory evoked potentials (SEPs) provide dorsal somatosensory system functional and localizing information, and complement motor evoked potentials. Correct application and interpretation require in-depth knowledge of relevant anatomy, electrophysiology, and techniques. It is advisable to facilitate cortical SEPs with total intravenous propofol-opioid or similarly favorable anesthesia. Moreover, SEP optimization is recommended to enhance surgical feedback speed and accuracy by maximizing signal-to-noise ratio (SNR); it consists of selecting highest-SNR peripheral and cortical derivations while omitting low-SNR channels...
November 14, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Sue Peters, Katlyn E Brown, S Jayne Garland, W Richard Staines, Todd C Handy, Bea A Francisco, Lara A Boyd
The ability to actively suppress, or gate, irrelevant sensory information is needed for safe and efficient walking in sensory-rich environments. Both attention and the late phase of motor preparation alter somatosensory evoked potentials (SEPs) in healthy adults. The aim of this study was to examine the effect of attention on the processing of irrelevant somatosensory information during the early phase of preparation of plantarflexion movements. Young healthy individuals received tibial nerve stimulation while electroencephalography (EEG) recorded SEPs over the Cz electrode...
November 20, 2018: Brain Research
Sohail Ahmad Malik, Ihsan Ahmad Qureshi, Raza Muhammad
BACKGROUND: Detection of foreign body oesophagus has always been a challenge for the otolaryngologists. Among different investigations available X -ray is valuable for detection of foreign bodies as it is readily available, inexpensive and easy to operate. However, this still remains to be decided that how accurate it is? The objective of the study is to determine the diagnostic accuracy of plain X ray lateral neck in the diagnosis of foreign bodies in cervical oesophagus keeping esophagoscopy as the gold standard...
July 2018: Journal of Ayub Medical College, Abbottabad: JAMC
Martin Unger, Andrea Morelli, Mervyn Singer, Peter Radermacher, Sebastian Rehberg, Helmut Trimmel, Michael Joannidis, Gottfried Heinz, Vladimír Cerny, Pavel Dostál, Christian Siebers, Fabio Guarracino, Francesca Pratesi, Gianni Biancofiore, Massimo Girardis, Pavla Kadlecova, Olivier Bouvet, Michael Zörer, Barbara Grohmann-Izay, Kurt Krejcy, Christoph Klade, Günther Krumpl
BACKGROUND: In patients with septic shock, the presence of an elevated heart rate (HR) after fluid resuscitation marks a subgroup of patients with a particularly poor prognosis. Several studies have shown that HR control in this population is safe and can potentially improve outcomes. However, all were conducted in a single-center setting. The aim of this multicenter study is to demonstrate that administration of the highly beta1-selective and ultrashort-acting beta blocker landiolol in patients with septic shock and persistent tachycardia (HR ≥ 95 beats per minute [bpm]) is effective in reducing and maintaining HR without increasing vasopressor requirements...
November 19, 2018: Trials
(no author information available yet)
Reports an error in "Not the same old thing: Establishing the unique contribution of drinking identity as a predictor of alcohol consumption and problems over time" by Kristen P. Lindgren, Jason J. Ramirez, Cecilia C. Olin and Clayton Neighbors ( Psychology of Addictive Behaviors , 2016[Sep], Vol 30[6], 659-671). In the article, in Table 2, the values reported for the Implicit ID Time interaction for the model predicting alcohol problems, when controlling for baseline consumption for the count portion of the model are incorrect...
November 2018: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
Gabriel Liberale, Paul H Sugarbaker
Sclerosing encapsulating peritonitis (SEP) is a rare entity characterized by encapsulation of the small bowel and/or the colon by a fibrous tissue that forms a shell. Intraperitoneal chemotherapy (IPC) has been reported to be a potential causative factor of secondary SEP. However, few studies have reported on secondary SEP related to cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Here, we review results from four clinical cases of SEP associated with CRS and HIPEC. In all four patients, additional surgery was necessary to alleviate recurrent episodes of small bowel obstruction...
December 2018: Surgical Oncology
S Lamy, R Guimbaud, L Digue, I Cirilo-Cassaigne, V Bousser, E Oum-Sack, J Goddard, E Bauvin, C Delpierre, P Grosclaude
BACKGROUND: Studies have shown clinical practices variation between centers in colorectal cancer (CRC) management. After the implementation of national cancer plans, we tested for differences in center and patients' socioeconomic position (SEP)-related variation in CRC guidelines. METHODS: All patients aged 18 years and over, cared for a first CRC in 2010 in Southwest of France. We used mixed effect model to test for center-related heterogeneity (CRH) in recommendation, from the oldest to the more recent: (1) at least 12 lymph nodes analysed for stage II, (2) the prescription of adjuvant chemotherapy stage III and (3) the assessment of CRC molecular phenotype regarding KRAS status for stage IV...
November 14, 2018: Clinics and Research in Hepatology and Gastroenterology
Laura Seiverling, Keith E Williams, Helen M Hendy, Whitney Adams, Stella Yusupova, Aleksandra Kaczor
The present study developed the 22-item Sensory Eating Problems Scale (SEPS) to measure sensory aspects for children surrounding eating, documented psychometrics of SEPS subscales, and examined their association with mealtime behavior problems. Study participants were 449 caretakers of children referred to feeding clinics, including children in three special needs status groups: autism spectrum disorder (ASD), other special needs, and no special needs. Caretakers completed surveys to report children's demographics, four measures of children's mealtime behavior problems, and five-point ratings for how often children showed various sensory feeding reactions...
November 14, 2018: Appetite
Linda Ejlskov, Henrik Bøggild, Claus D Hansen, Jesper Wulff, Steen M Hansen, Liis Starkopf, Theis Lange, Thomas Gerds, Christian Torp-Pedersen
Background: Early-life socioeconomic position (SEP) is associated with lifestyle-related diseases in adulthood. However, evidence is lacking on the extent to which adult SEP mediates this association. Methods: Time to either chronic obstructive pulmonary disease (COPD), cardiovascular disease or diabetes were assessed in the Danish population born between 1961 and 1971 (n = 793 674) from age 30 until 2015. Early-life position was assessed in 1981 (by parental) and again at age 30 (own) by four markers; income, occupation, education-divided into high, middle, low-and a combined score for all markers...
November 14, 2018: European Journal of Public Health
Lihui Wang, Yihong Ye
In this issue of Molecular Cell, Weith et al. (2018) demonstrate that p97, together with a SEP adaptor, can catalyze ordered subunit exchange to facilitate the biogenesis of protein phosphatase-1 (PP1) holoenzyme, establishing a novel ubiquitin-independent "segregase" function for this versatile ATPase.
November 15, 2018: Molecular Cell
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