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SEP or micropeptides

Yangyang Yang, Jun Hou, Peifang Wang, Chao Wang, Xun Wang, Guoxiang You
The presence of abundant extracellular polymeric substances (EPS) play a vital role in affecting heteroaggregation process and toxicity of nanoparticles (NPs) to Microcystis aeruginosa. Interactions between n-CeO2 and cyanobacteria with/without EPS and the toxicity of n-CeO2 to M. aeruginosa were investigated in this study. Aggregation kinetics of n-CeO2 under both soluble EPS (SEPS) and bound EPS (BEPS) indicated the presence of EPS could induced the formation of EPS-NPs aggregates. Heteroaggregation between cells and n-CeO2 was confirmed through co-settling experiment and SEM-EDS observation...
August 7, 2018: Environmental Pollution
Hussain Al-Thaiban, Nada Al-Tamimi, Murad Helaleh
A simple and fast method for the determination of PAHs in smoked meat samples was described. The QuEChERS (Z-Sep) procedure was used for sample preparation. Gas chromatograph-mass spectrometer with electron ionization (EI) was used to separate and detect the PAHs. All 16 common PAHs were analyzed successfully. Matrix-matched calibration was applied. Spiked samples were performed at 1 ng/g ( n =10) and 10 ng/g ( n =10) for two days. Overall recoveries of PAHs were within 74 to 117%, with RSDs within 1.15 to 37...
2018: Journal of Analytical Methods in Chemistry
Emily A Knapp, Lorraine T Dean
PURPOSE: Credit scores may operate as a socioeconomic indicator of health: they represent cumulative financial history that directly influences ability to access financial and nonfinancial resources related to health. Yet, little is known about the relationship of credit score and health or to traditional measures of socioeconomic position (SEP). Our objectives were to (1) evaluate the association between area-level credit score and individual self-rated health and (2) compare credit score to traditional markers of area-level SEP in predicting self-rated health...
July 31, 2018: Annals of Epidemiology
Jong-Shik Kim, In-Kyoung Lee, Bong-Sik Yun
Yeast biosurfactants have potent applications in medical, cosmeceutical, and food industries due to their specific modes of action, low toxicity, and applicability. In this study, biosurfactant-producing yeasts were screened for various industrial applications. Among them, Aureobasidium pullulans strain A11211-4-57 with potent surfactant activity from fleabane flower, Erigeron annus (L.) pers., was selected. From culture supernatant of strain A11211-4-57, five new low-surface-tension chemicals designated as pullusurfactans A-E were identified through consecutive chromatography steps, involving ODS, silica gel, Sephadex LH-20, and ODS Sep-pak cartridge columns...
August 15, 2018: Journal of Antibiotics
Li-Juan Wang, Xi-Feng Wu, Ling Sun, Wei Zhuang, Qiang Song
OBJECTIVE: To compare the clinical efficacy of small dose CAG regimen and MA regimen in the senile patients with acute myeloid leukemia(AML). METHODS: The clinical data of 83 senile patients with AML from Sep. 2012 to Sep. 2016 in our Hospital were analyzed retrospectively. According to the chemotherapy regimens, the patients were divided into CAG group and MA group; 36 patients in CAG group were treated with small dose CAG, while 47 patients in MA group were treated with MA...
August 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
Anders Emanuelsen, Michael Voigt, Pascal Madeleine, Pia Kjær, Sebastian Dam, Nikolaj Koefoed, Ernst A Hansen
Voluntary rhythmic movements, such as, for example, locomotion and other cyclic tasks, are fundamental during everyday life. Patients with impaired neural or motor function often take part in rehabilitation programs, which include rhythmic movements. Therefore, it is imperative to have the best possible understanding of control and behaviour of human voluntary rhythmic movements. A behavioural phenomenon termed repeated bout rate enhancement has been established as an increase of the freely chosen index finger tapping frequency during the second of two consecutive tapping bouts...
2018: Frontiers in Neuroscience
Marilia B Antonio, Gabriel T Cuba, Ricardo P Vasconcelos, Ana Paula P S Alves, Bruna Oliveira da Silva, Vivian Iida Avelino-Silva
BACKGROUND: Although doxycycline is widely used as alternative to benzathine penicillin for the treatment of early and late latent syphilis, data on serological response following treatment with doxycycline among HIV-infected patients is limited. METHODS: In this study, we analyzed serological response to syphilis treatment with doxycycline among HIV-infected patients treated during a benzathine penicillin shortage period and compared with treatment response among patients treated with benzathine penicillin...
August 9, 2018: AIDS
Jane Maddock, Wahyu Wulaningsih, Juan Castillo Fernandez, George B Ploubidis, Alissa Goodman, Jordana Bell, Diana Kuh, Rebecca Hardy
BACKGROUND: Body size, nutrition and socioeconomic position (SEP) in early life have been associated with a wide range of long-term health effects. Epigenetics is one possible mechanism through which these early life exposures can impact later life health. We conducted a systematic review examining the observational evidence for the impact of body size, nutrition and SEP in early life on the epigenome in humans. METHODS: This systematic review is registered with the PROSPERO database (registration number: CRD42016050193)...
2018: PloS One
Gerrit Groenhof, Jussi Toppari
When photoactive molecules interact strongly with confined light modes, new hybrid light-matter states may form: the polaritons. These polaritons are coherent super-positions of excitations of the molecules and of the cavity photon. Recently, po-laritons were shown to mediate energy transfer be-tween chromophores at distances beyond the Förster limit. Here we explore the potential of strong coupling for light-harvesting applications by means of atomistic molecular dynamics simulations of mixtures of photo-reactive and non-photo-reactive molecules strongly coupled to a single con-fined light mode...
August 7, 2018: Journal of Physical Chemistry Letters
Sheng Wang, Shiyang Fei, Zongan Wang, Yu Li, Jinbo Xu, Feng Zhao, Xin Gao
Summary: PredMP is the first web service, to our knowledge, that aims at de novo prediction of the membrane protein (MP) 3D structure followed by the embedding of the MP into the lipid bilayer for visualization. Our approach is based on a high-throughput Deep Transfer Learning (DTL) method that first predicts MP contacts by learning from non-MPs and then predicts the 3D model of the MP using the predicted contacts as distance restraints. This algorithm is derived from our previous Deep Learning (DL) method originally developed for soluble protein contact prediction, which has been officially ranked No...
August 4, 2018: Bioinformatics
Jie Xu, Xin Zhou, Xiaoguang Guo, Guoyou Wang, Shijie Fu, Lei Zhang
BACKGROUND Anterior cruciate ligament (ACL) injury can cause knee proprioception degeneration, on which the electroacupuncture (EA) treatment has a definite effect. However, it is still not clear whether conducting EA intervention on the injured side can promote bilateral proprioception recovery. MATERIAL AND METHODS We randomly selected 6 of 9 normal cynomolgus monkeys to develop unilateral ACL injury models via arthroscopy. All knees were divided into 5 groups: the normal control (NC) group, injured side of blank model (ISBM) group, contralateral side of blank model (CSBM) group, injured side of EA (ISE) group, and contralateral side of EA (CSE) group...
August 7, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Tao Qi, Lei Ye, Zheng Chen, Zhan-Sen Huang, Bo Wang, Hao Li, Bin Zhang, Jun Chen
This study is aimed to evaluate the effectiveness and safety of the treatment of highflow priapism with superselective transcatheter embolization. From Sep. 1999 to Jan. 2013, six patients with high-flow priapism underwent superselective transcatheter embolization of the cavernous artery. Recurrence of priapism, and change in erectile function detected by nocturnal penile tumescence and rigidity (NPTR) test and the International Index of Erectile Function 5-item questionnaire (IIEF-5) were evaluated during a mean follow-up of 12 months...
February 2018: Current medical science
Jieyun Hu, Lu Lin, Min Chen, Weiling Yan
Staphylococcal enterotoxins (SEs) produced by Staphylococcus aureus ( S. aureus ) are the cause of Saphylococcal food poisoning (SFP) outbreaks. Thus, estimation of the time to detection (TTD) of SEs, that is, the time required to reach the SEs detection limit, is essential for food preservation and quantitative risk assessment. This study was conducted to explore an appropriate method to predict the TTD of SEs in cooked chicken product under variable environmental conditions. An S. aureus strain that produces staphylococcal enterotoxin A (SEA) was inoculated into cooked chicken meat...
2018: Frontiers in Microbiology
Berta Baca-Bocanegra, Julio Nogales-Bueno, Francisco José Heredia, José Miguel Hernández-Hierro
Near infrared hyperspectral data were collected for 200 Syrah and Tempranillo grape seed samples. Next, a sample selection was carried out and the phenolic content of these samples was determined. Then, quantitative (modified partial least square regressions) and qualitative (K-means and lineal discriminant analyses) chemometric tools were applied to obtain the best models for predicting the reference parameters. Quantitative models developed for the prediction of total phenolic and flavanolic contents have been successfully developed with standard errors of prediction (SEP) in external validation similar to those previously reported...
July 26, 2018: Sensors
Matthew M Hamill, Louise Seppings, Vivienne Kit, Sheelah Antao
We believe this to be the first report of co-existing PCR-confirmed primary genital and ocular syphilis in a patient with penicillin allergy treated with doxycycline. The case examines the use of non-penicillin and corticosteroid treatment of ocular syphilis and highlights the risk of eye involvement early in the disease process.
July 24, 2018: Sexually Transmitted Diseases
Fatma W Nazer, Wael Sabbah
Objective: To assess whether there are ethnic differences in tooth loss among adult Americans aged <40 years and whether socioeconomic position attenuates these differences if they exist. Methods: Data were from the 2014 Behavioral Risk Factor Surveillance System, a health-related telephone cross-sectional survey of a nationally representative sample of US adults. Tooth loss (one tooth or more) was used as the outcome variable. Ethnicity was the main explanatory variable...
2018: Ethnicity & Disease
Richard Knochenmuss, Surajit Maity, Franziska Balmer, Charlotte Müller, Samuel Leutwyler
Using the stimulated-emission-pumping/resonant 2-photon ionization (SEP-R2PI) method, we have determined accurate intermolecular dissociation energies D0 of supersonic jet-cooled intermolecular complexes of 1-naphthol (1NpOH) with alkanes, 1NpOH·S, with S = methane, ethane, propane, and n-butane. Experimentally, the smaller alkanes form a single minimum-energy structure, while 1-naphthol·n-butane forms three different isomers. The ground-state dissociation energies D0 (S0 ) for the complexes with propane and n-butane (isomers A and B) were bracketed within ±0...
July 21, 2018: Journal of Chemical Physics
Mattia F Pagnotta, Mukesh Dhamala, Gijs Plomp
Brain function arises from networks of distributed brain areas whose directed interactions vary at subsecond time scales. To investigate such interactions, functional directed connectivity methods based on nonparametric spectral factorization are promising tools, because they can be straightforwardly extended to the nonstationary case using wavelet transforms or multitapers on sliding time window, and allow estimating time-varying spectral measures of Granger-Geweke causality (GGC) from multivariate data. Here we systematically assess the performance of various nonparametric GGC methods in real EEG data recorded over rat cortex during unilateral whisker stimulations, where somatosensory evoked potentials (SEPs) propagate over known areas at known latencies and therefore allow defining fixed criteria to measure the performance of time-varying directed connectivity measures...
July 20, 2018: NeuroImage
Enrico De Martino, Matteo Zandalasini, Siobhan Schabrun, Laura Petrini, Thomas Graven-Nielsen
Impaired corticomotor function is reported in patients with lateral epicondylalgia, but the causal link to pain or musculotendinous overloading is unclear. In this study, sensorimotor cortical changes were investigated using a model of persistent pain combined with an overloading condition. In 24 healthy subjects, the effect of nerve growth factor (NGF) induced pain, combined with delayed onset muscle soreness (DOMS), was examined on pain perception, pressure pain sensitivity, maximal force, and sensorimotor cortical excitability...
July 20, 2018: Pain
Russel C G Chidya, Sherif M Abdel-Dayem, Kazuhiko Takeda, Hiroshi Sakugawa
This study investigated spatio-temporal variations of selected pesticide residues in the Kurose River in Higashi-Hiroshima city (Hiroshima Prefecture), Japan. Water samples were collected from the river at seven sites every month for 1 year (March 2016 to February 2017). Pesticide residues were extracted from the samples by a solid phase extraction using Sep Pack C18 cartridges. Once extracted, the samples were analyzed for cyanazine, simetryn, fenarimol, isoprothiolane, and diazinon using a reversed-phase high-performance liquid chromatography ultraviolet visible (HPLC-UV Vis) system...
July 23, 2018: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
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