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https://www.readbyqxmd.com/read/30537080/dressings-and-topical-agents-for-preventing-pressure-ulcers
#1
REVIEW
Zena Eh Moore, Joan Webster
BACKGROUND: Pressure ulcers, localised injuries to the skin or underlying tissue, or both, occur when people cannot reposition themselves to relieve pressure on bony prominences. These wounds are difficult to heal, painful, expensive to manage and have a negative impact on quality of life. Prevention strategies include nutritional support and pressure redistribution. Dressing and topical agents aimed at prevention are also widely used, however, it remains unclear which, if any, are most effective...
December 6, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/30527658/in-vitro-evaluation-of-the-polymerization-properties-of-n-butyl-cyanoacrylate-iodized-oil-mixtures-for-lymphatic-interventions
#2
Daniel Kuetting, Hans H Schild, Claus C Pieper
PURPOSE: To evaluate polymerization of N-butyl cyanoacrylate (NBCA)/iodized oil mixtures for lymphatic interventions in vitro. MATERIALS AND METHODS: Polymerization times of different NBCA/iodized oil mixtures (ratios of 1:0-1:7) were investigated in a static and dynamic experimental setup (performed in a lymph flow model in a silicone tube). Eight lymphatic samples with different triglyceride (TG) concentrations (low TGs, < 50 mg/dL; medium TGs, approximately 100-400 mg/dL; high TGs, > 700 mg/dL) were investigated...
December 6, 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/30509075/freeze-float-selection-of-ice-nucleators
#3
Yuki Kamijo, Ratmir Derda
In this manuscript, we developed a screening system that employs the difference in density between liquid water and ice (0.9998 g/cm3 v.s. 0.9168 g/cm3 at 0 °C) to identify ice-nucleating agents (INAs) that are encapsulated into droplets of water suspended in silicone oil of intermediate density (0.939 g/cm3 ). Droplets of liquid water stably reside at the interface of the silicone oil and perfluoro oil (1.6658 g/cm3 ); freezing causes the aqueous droplets to float to the top of the silicone oil layer. We demonstrated the feasibility of this screening system by using droplets that contained well-defined ice-nucleator Snomax...
December 4, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/30506018/fine-particle-sources-and-cognitive-function-in-an-older-puerto-rican-cohort-in-greater-boston
#4
Renee Wurth, Marianthi-Anna Kioumourtzoglou, Katherine L Tucker, John Griffith, Justin Manjourides, Helen Suh
Background: Puerto Ricans living in the mainland US have substantially higher rates of impairment to cognitive performance as compared to non-Hispanic Whites, with air pollutant exposures a potential risk factor. We investigated whether exposures to specific air pollution sources were associated with performance across several cognitive domains in a cohort of Puerto Rican older adults. Objectives: To investigate the association between sources of PM2.5 and cognitive performance in each of five cognitive domains...
September 2018: Environmental epidemiology
https://www.readbyqxmd.com/read/30505129/surgical-outcome-in-optic-disc-pit-maculopathy
#5
Ronel Soibam, Parvez Ahmad Bhat, Manabjyoti Barman, Harsha Bhattacharjee, Arsalan Un Nisa
The purpose of this study was to present the surgical outcome in optic disc pit associated maculopathy in a patient who was treated with vitrectomy, internal limiting membrane (ILM) peeling, barrage laser photocoagulation, and silicone oil tamponade. A 21-year-old Indian male was diagnosed with optic disc pit maculopathy in his left eye with a best-corrected visual acuity (BCVA) of 20/200. A 23-gauge pars plana vitrectomy with peeling of ILM was done using brilliant blue dye. After completion of vitrectomy, fluid-air exchange was performed and silicone oil was instilled into eye...
September 2018: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/30504664/-toward-the-proper-biophysical-characterization-of-aggregates-in-biopharmaceuticals
#6
Susumu Uchiyama
Biopharmaceuticals are often formulated as liquid dosage forms. During manufacturing and storage, protein molecules and active pharmaceutical ingredients form aggregates due to various stresses, including shaking and agitation, as well as by contact with silicone oils coated on pre-fillable syringes. The diameter of protein aggregates ranges from 15-20 nm, and that of dimers comprising a large number of antibody molecules can be up to 100 μm. Among these aggregates, those with a diameter of <100 nm are called nanometer aggregates, while those ranging between 100 nm and 1 μm are called sub-micron aggregates, and those ranging between 1 and 100 μm are called micron aggregates...
2018: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/30501760/squeeze-strengthening-effect-of-silicone-oil-based-magnetorheological-fluid-with-nanometer-fe%C3%A2-o%C3%A2-addition-in-high-torque-magnetorheological-brakes
#7
Ningning Wang, Xinhua Liu, Xiaohui Zhang
With the aim of studying the squeeze-strengthening effect of silicone oil-based magnetorheological fluid (MRF) with nanometer Fe₃O₄ addition in high-torque magnetorheological (MR) brakes, the theoretical analysis of the disc brake is presented and a high-torque squeezing MRF brake with a water cooling method for heat dissipation is designed. Furthermore, an experimental system to evaluate the squeeze-strengthening performance of the MRF in the high-torque MR brake is established and relevant experiments are performed...
May 1, 2019: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/30496028/vitrectomy-with-silicone-oil-tamponade-in-rhegmatogenous-retinal-detachment-following-acute-retinal-necrosis-clinical-outcomes-and-prognostic-factors
#8
Vivek Pravin Dave, Rajeev R Pappuru, Avinash Pathengay, Mudit Tyagi, Raja Narayanan, Subhadra Jalali
PURPOSE: The purpose of the study is to report the prognostic factors and outcomes of vitrectomy (PPV) with silicone oil tamponade in rhegmatogenous retinal detachment (RRD) secondary to acute retinal necrosis (ARN). METHODS: This retrospective, non-randomized, interventional comparative study included 38 eyes of 38 patients. All cases underwent PPV with silicone oil tamponade. The main outcome measure was improvement of final visual acuity relative to the presenting visual acuity and factors affecting the same Group A included eyes with favorable vision of 20/400 or better and Group B included the others...
November 29, 2018: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/30487050/silicone-based-simulation-models-for-peripheral-nerve-microsurgery
#9
Burcin Ustbas Gul, Deniz Kilic Yanilmaz, Dilan Arslan, Mehmet Bayramicli, Ozge Akbulut
BACKGROUND: There is a need for a peripheral nerve model on which surgeons-in-training can simulate the repair of nerve injuries at their own pace. Although practicing on animal models/cadavers is considered the "gold standard" of microsurgical training, the proposed model aims to provide a platform for improving the technical skills of surgical trainees prior to their practice on cadaver/animal models. In addition, this model has the potential to serve as a standardized test medium for assessing the skill sets of surgeons...
November 15, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/30486345/facile-oil-removal-from-water-in-oil-stable-emulsions-using-pu-foams
#10
Suset Barroso-Solares, Javier Pinto, Despina Fragouli, Athanassia Athanassiou
Superhydrophobic and oleophilic polyurethane foams were obtained by spray-coating their surfaces with solutions of thermoplastic polyurethane and hydrophobic silicon oxide nanoparticles. The developed functionalized foams were exploited as reusable oil absorbents from stable water-in-oil emulsions. These foams were able to remove oil efficiently from a wide range of emulsions with oil contents from 10 to 80 v.%, stabilized using Span80. The modified foams could reach oil absorption capacities up to 29 g/g, becoming a suitable candidate for water-in-oil stable emulsions separation...
November 27, 2018: Materials
https://www.readbyqxmd.com/read/30484963/adhesion-of-silicone-oil-and-emulsification-an-in-vitro-assessment-using-a-microfluidic-device-and-eye-on-a-chip
#11
Yongjie Lu, Yau Kei Chan, Long Hei Lau, Youchuang Chao, Kendrick Co Shih, Shiu Ming Lai, David Wong, Ho Cheung Shum
PURPOSE: Silicone oil (SiO) with additives of high-molecular-weight (HMW) SiO molecules, eases both the injection and removal. When used inside an eye, it remains unclear how increasing extensional viscosity of SiO might reduce emulsification. Using cell-lined models, this study aims to understand the reason why SiO with HMW is less prone to emulsification. METHODS: The adhesion of SiO was studied and recorded in a cell-coated microchannel by optical microscopy...
November 28, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30471289/quantification-of-silicone-oil-and-its-degradation-products-in-aqueous-pharmaceutical-formulations-by-1h-nmr-spectroscopy
#12
Joan Malmstrøm
During the past years there has been an increasing focus on the presence of silicone oil as a contaminant in pharmaceutical formulations kept in pre-filled syringes. As the pre-filled syringes are coated on the inner wall with silicone oil (PDMS) there is a potential risk that the oil can migrate from the inner surface of the primary packing material into the aqueous solution. Several studies have demonstrated that presence of silicone oil as droplets in a high-concentrated protein formulation can cause protein aggregation...
November 21, 2018: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/30468871/small-scale-culture-of-plasmodium-falciparum-using-%C3%AE-slide-angiogenesis-followed-by-automatic-infection-rate-counting-to-assess-drug-effects
#13
Muneaki Hashimoto, Yusuke Ido, Masato Tanaka, Kazumichi Yokota, Kazuaki Kajimoto, Masatoshi Kataoka
It is very important to reduce the costs involved in malarial drug development by small-scale culture of Plasmodium falciparum, and automation of the assay system for drug efficacy against the parasites for high-throughput screening. In this study, we report that P. falciparum-infected erythrocytes can be stably cultured on μ-Slide Angiogenesis, which is used to investigate angiogenesis in tube formation assays, followed by automatic counting of the infection rate (parasitaemia). After 10 μL of parasite-infected erythrocytes were added to the inner well of μ-Slide Angiogenesis to prevent a multilayer of erythrocytes, 30 μL of silicon oil was overlaid on the culture medium to avoid evaporation of the medium, leading to stable small-scale parasite cultivation...
November 20, 2018: Parasitology International
https://www.readbyqxmd.com/read/30457153/colloidal-stability-dictates-drop-breakup-under-electric-fields
#14
Javier A Lanauze, Rajarshi Sengupta, Blake J Bleier, Benjamin A Yezer, Aditya S Khair, Lynn M Walker
Electric fields can deform drops of fluid from their equilibrium shape, and induce breakup at sufficiently large field strengths. In this work, the electric field induced breakup of a squalane drop containing a colloidal suspension of carbon black particles with polyisobutylene succinimide (OLOA 11000) surfactant is studied. The drop is suspended in silicone oil. The breakup mode of a drop containing carbon black depends strongly on the suspension stability. It is observed that a drop of a stable suspension of carbon black has the same breakup mode as a drop with surfactant alone, i...
November 28, 2018: Soft Matter
https://www.readbyqxmd.com/read/30457137/disposable-silicon-glass-microfluidic-devices-precise-robust-and-cheap
#15
ZhenBang Qi, Lining Xu, Yi Xu, Junjie Zhong, Ali Abedini, Xiang Cheng, David Sinton
Si-glass microfluidics have long provided unprecedented precision, robustness and optical clarity. However, chip fabrication is costly (∼500 USD per chip) and in practice, devices are not heavily reused. We present a method to reduce the cost-per-chip by two orders of magnitude (∼5 USD per chip), rendering Si-glass microfluidics disposable for many applications. The strategy is based on reducing the area of the chip and a whole-chip manifolding strategy that achieves reliable high-pressure high-temperature fluid connectivity...
November 20, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/30456320/production-of-hollow-type-spherical-bacterial-cellulose-as-a-controlled-release-device-by-newly-designed-floating-cultivation
#16
Toru Hoshi, Kazuyoshi Yamazaki, Yuki Sato, Takaya Shida, Takao Aoyagi
We developed a novel cultivating system for hollow-type spherical bacterial cellulose (HSBC) gel production without any molds or template. It consisted of floating aqueous medium droplet containing Gluconacetobacter xylinus ( G. xylinus ) at the boundary of two non-mixed silicone oil layers. The fibrils of bacterial cellulose (BC) were produced at the interface of water and oil phases. Fibril layers effectively thickened layer-by-layer and eventually formed a shell structure. The size of the HSBC gel can be controlled by the volume of dropped cell suspension...
October 2018: Heliyon
https://www.readbyqxmd.com/read/30453027/silicone-oil-migration-into-periorbital-space-surrounding-an-extraocular-muscle-after-sutureless-23-gauge-vitrectomy-in-a-child
#17
Jessica Ruzicki, Sarah Simpson, James Farmer, Peter J Kertes, Yi Ning J Strube
No abstract text is available yet for this article.
November 16, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/30451195/bimanual-25-gauge-chandelier-technique-for-direct-perfluorocarbon-liquid-silicone-oil-exchange-in-retinal-detachments-associated-with-giant-retinal-tear
#18
Stuti Astir, Daraius N Shroff, Charu Gupta, Cyrus M Shroff, Indranil Saha, Ranjan Dutta
Direct perfluorocarbon liquid (PFCL)-silicone oil exchange presents its own set of challenges in the micro incision vitreous surgery era. We propose a simple bimanual technique to circumvent this problem. Thirteen eyes of patients with retinal detachment associated with giant retinal tears underwent vitrectomy followed by self-retaining endo illuminator (Chandelier) assisted direct PFCL-silicone exchange. No intra or postoperative complications related to the surgical technique were noted. All patients had attached retinas and satisfactory visual recovery at 6 months...
December 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/30450308/air-tamponade-and-without-heavy-liquid-usage-in-pars-plana-vitrectomy-for-rhegmatogenous-retinal-detachment-repair
#19
Zhong Lin, Qi-Hua Liang, Ke Lin, Zhi-Xiang Hu, Tian-Yu Chen, Rong-Han Wu, Nived Moonasar
AIM: To report the results of rhegmatogenous retinal detachment (RRD) repair after pars plana vitrectomy (PPV) without operative use of heavy liquid, and utilizing air tamponade in selected cases. METHODS: RRD patients without severity of proliferative vitreoretinopathy C2 or more underwent PPV without operative use of heavy liquid, and utilizing air tamponade were consecutively enrolled. Alternative postoperative facedown position or lateral position was required for 3-5d...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/30446552/diversity-in-co-2-concentrating-mechanisms-among-chemolithoautotrophs-from-genera-hydrogenovibrio-thiomicrorhabdus-and-thiomicrospira-ubiquitous-in-sulfidic-habitats-worldwide
#20
Kathleen M Scott, Juliana M Leonard, Rich Boden, Dale Chaput, Clare Dennison, Edward Haller, Tara L Harmer, Abigail Anderson, Tiffany Arnold, Samantha Budenstein, Rikki Brown, Juan Brand, Jacob Byers, Jeanette Calarco, Timothy Campbell, Erica Carter, Max Chase, Montana Cole, Deandra Dwyer, Jonathon Grasham, Christopher Hanni, Ashlee Hazle, Cody Johnson, Ryan Johnson, Brandi Kirby, Katherine Lewis, Brianna Neumann, Tracy Nguyen, Jonathon Nino Charari, Ooreoluwa Morakinyo, Bengt Olsson, Shanetta Roundtree, Emily Skjerve, Ashley Ubaldini, Robert Whittaker
Members of Hydrogenovibrio, Thiomicrospira and Thiomicrorhabdus fix carbon at hydrothermal vents, coastal sediments, hypersaline lakes, and other sulfidic habitats. The genome sequences of these ubiquitous and prolific chemolithoautotrophs suggest a surprising diversity of mechanisms for dissolved inorganic carbon (DIC) uptake and fixation; these mechanisms are verified here. Carboxysomes are apparent in transmission electron micrographs of most of these organisms; lack of carboxysomes in Thiomicrorhabdus sp...
November 16, 2018: Applied and Environmental Microbiology
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