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Rishabh C Date, Emmanuel Y Chang, Veeral S Shah
PURPOSE: To present a case of visually significant retinal injury due to internal limiting membrane (ILM) peeling using ILM forceps alone. METHODS: Case report. RESULTS: A 60-year-old woman who underwent ILM peeling for an epiretinal membrane presented with linear central scotomata. Peeling had been initiated and performed with ILM forceps alone, without the use of other surgical instruments. Fundus examination and spectral domain optical coherence tomography imaging confirmed the presence of several discrete areas of inner and outer retinal injury in the macula, which corresponded to her scotomata...
August 2, 2018: Retinal Cases & Brief Reports
Peipei Zhou, Kai Chen, Man Gao, Jingang Qu, Zhanen Zhang, Randy A Dahlgren, Yanyan Li, Wei Liu, Hong Huang, Xuedong Wang
Conventional magnetic effervescent tablet has many drawbacks, such as not practicable for field processing, rapid moisture absorption, and poor tablet storage characteristics. Herein, we developed a novel magnetic effervescent tablet containing ionic liquid microextraction (MET-ILM) for determination of pyrethroids in dairy milk. It contains only Na2 CO3 as an alkali source (no acidic source) in the Fe3 O4 magnetic tablet; the CO2 -forming reaction is initiated in the acidic solution containing the analytes, and thus the prepared tablet can be stored for long time periods without deterioration...
December 1, 2018: Food Chemistry
Andrea Russo, Francesco Morescalchi, Elena Gambicorti, Anna Cancarini, Ciro Costagliola, Francesco Semeraro
PURPOSE: To compare the retinal sensitivity after complete internal limiting membrane (ILM) peeling with that after foveal-sparing ILM peeling during vitrectomy for Type I epiretinal membrane. METHODS: This was a prospective, randomized, comparative study. Thirty-eight eyes were randomized to undergo complete peeling of the ILM (CP group) or peeling with foveal sparing (FS group). The main outcome measures were foveal and perifoveal retinal sensitivity, visual acuity, and central retinal thickness...
July 30, 2018: Retina
Tian Tian, Haiying Jin, Qi Zhang, Xiang Zhang, Hongtao Zhang, Peiquan Zhao
PURPOSE: To investigate the long-term results of a modified technique for parafoveal multiple curvilinear internal limiting membrane (ILM) peeling to preserve the epi-foveal ILM in myopic foveoschisis surgery. METHODS: Thirty-two consecutive patients (36 eyes) were retrospectively reviewed. Patients were divided into two groups according to the extent of ILM peeled: the fovea-sparing ILM peeling group (FS) (18 eyes) and total ILM peeling group (TP) (18 eyes). Patients were followed up for at least 12 months...
July 30, 2018: Eye
Naresh Babu Kannan, Piyush Kohli, Haemoglobin Parida, O O Adenuga, Kim Ramasamy
BACKGROUND: The anatomical success rate of macular hole surgery ranges around 93-98%. However, the prognosis of large macular holes is generally poor. The study was conducted to compare the anatomical and visual outcomes of Internal Limiting Membrane (ILM) peeling vis-a-vis inverted ILM flap for the treatment of idiopathic large Full-Thickness Macular Holes (FTMH). METHODS: This was a prospective randomized control trial. The study included patients with idiopathic FTMH, with a minimum diameter ranging from 600 to 1500 μm...
July 20, 2018: BMC Ophthalmology
Kelvin Yi Chong Teo, Shu Yen Lee, Amutha Veluchamy Barathi, Sai Bo Bo Tun, Licia Tan, Ian Jeffery Constable
Purpose: To determine if the surgical removal of the internal limiting membrane (ILM) in nonhuman primates (NHPs) will result in safe and effective transfection of adeno-associated viral (AAV2) vectors using green fluorescent protein (GFP) as a reporter. Methods: Six Macaca fascicularis NHP eyes underwent vitrectomy, ILM peel with layering of 1.7 × 1013 genome copies per milliliter of AAV2-GFP under air. Four control eyes underwent only vitrectomy and pooling under air...
July 2, 2018: Investigative Ophthalmology & Visual Science
Matteo Fallico, Andrea Russo, Antonio Longo, Alfredo Pulvirenti, Teresio Avitabile, Vincenza Bonfiglio, Niccolò Castellino, Gilda Cennamo, Michele Reibaldi
BACKGROUND: Internal limiting membrane (ILM) peeling during primary vitrectomy for rhegmatogenous retinal detachment (RRD) prevents the formation of postoperative macular epiretinal membrane (ERM). However, studies that compared vitrectomy with and without ILM peeling for RRD, have reported controversial outcomes. OBJECTIVE: To assess the efficacy of ILM peeling versus non-ILM peeling during vitrectomy for RRD by a systematic review and meta-analysis of published studies...
2018: PloS One
Javad Tavakoli, John J Costi
The mechanical role of elastic fibers in the inter-lamellar matrix (ILM) is unknown; however, it has been suggested that they play a role in providing structural integrity to the annulus fibrosus (AF). Therefore, the aim of this study was to measure the viscoelastic and failure properties of the elastic fiber network in the ILM of ovine discs under both tension and shear directions of loading. Utilizing a technique, isolated elastic fibers within the ILM from ovine discs were stretched to 40% of their initial length at three strain rates of 0...
July 12, 2018: Acta Biomaterialia
Megh D Patel, Fareshta Khushzad, Heather E Moss
Background: Optic nerve head measurements extracted from optical coherence tomography (OCT) show promise for monitoring clinical conditions with elevated optic nerve heads. The aim of this study is to compare reliability within and between raters and between image acquisition devices of optic nerve measurements derived from OCT scans in eyes with varying degrees of optic nerve elevation. Methods: Wide angle line scans and narrow angle radial scans through optic nerve heads were obtained using three spectral domain(SD) OCT devices on 5 subjects (6 swollen optic nerves, 4 normal optic nerves)...
2018: Eye and Vision (London, England)
Li-Anne S Lim, Guillermo Fernandez-Sanz, Steven Levasseur, John R Grigg, Alex P Hunyor
Background: Macular holes in children are generally associated with trauma. Case presentation: We report the first case of an idiopathic full thickness macular hole in a 10-year-old girl. 23-gauge transconjunctival pars plana vitrectomy, induction of a posterior vitreous detachment, ILM blue-assisted internal limiting membrane peel, fluid-air exchange and air-26% sulfur hexafluoride (SF6) exchange was performed with subsequent macular hole closure. Conclusion: This is the first reported case of an idiopathic full thickness macular hole in a child...
2018: International Journal of Retina and Vitreous
Matias Iglicki, Alejandro Lavaque, Malgorzata Ozimek, Hermino Pablo Negri, Mali Okada, Jay Chhablani, Catharina Busch, Anat Loewenstein, Dinah Zur
PURPOSE: We aimed to investigate biomarkers and predictive factors for visual and anatomical outcome in patients with naïve diabetic macular edema (DME) who underwent small gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling as a first line treatment. DESIGN: Multicenter, retrospective, interventional study. PARTICIPANTS: 120 eyes from 120 patients with naïve DME treated with PPV and ILM peeling with a follow up of 24 months...
2018: PloS One
Nicolas A Yannuzzi, Natalia F Callaway, Jayanth Sridhar, William E Smiddy
PURPOSE: To evaluate the visual and potential economic impact of primary internal limiting membrane (ILM) peeling in primary treatment of rhegmatogenous retinal detachment. METHODS: A PubMed search was performed to extract data regarding the rate of epiretinal membrane formation and the rate of secondary pars plana vitrectomy with membrane peel after repair of rhegmatogenous retinal detachment with or without ILM peeling. Data were aggregated and analyzed in a meta-analysis...
July 9, 2018: Retina
J L Lauermann, A K Woetzel, M Treder, M Alnawaiseh, C R Clemens, N Eter, Florian Alten
PURPOSE: To assess the prevalences of segmentation errors and motion artifacts in optical coherence tomography angiography (OCT-A) in different retinal diseases METHODS: In a retrospective analysis, multimodal retinal imaging including OCT-A was performed in one eye of 57 healthy controls (50.96 ± 22.4 years) and 149 patients (66.42 ± 14.1 years) affected by different chorioretinal diseases: early/intermediate age-related macular degeneration (AMD; n = 26), neovascular AMD (nAMD; n = 22), geographic atrophy due to AMD (GA; n = 6), glaucoma (n = 28), central serous chorioretinopathy (CSC; n = 14), epiretinal membrane (EM; n = 26), retinal vein occlusion (RVO; n = 11), and retinitis pigmentosa (RP; n = 16)...
July 7, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Jae Hyan Kim, Seong-Il Bin, Bum-Sik Lee, Jong-Min Kim, Nam-Ki Kim, Chang-Rack Lee
INTRODUCTION: Little is known about peripheral rim instability (PRI) of adult discoid lateral meniscus (DLM). We compared PRI of the intact DLM (iDLM) to those of intact normal lateral meniscus (LM) in adult patients and also investigated whether there was any association between PRI and DLM tears. MATERIALS AND METHODS: We investigated PRI in 17 DLMs and 60 normal LMs without tears during arthroscopic surgery for medial compartmental pathologies between June 2012 and October 2015...
July 5, 2018: Archives of Orthopaedic and Trauma Surgery
Mario R Romano, Gennaro Ilardi, Mariantonia Ferrara, Gilda Cennamo, Barbara Parolini, Cesare Mariotti, Stefania Staibano, Giovanni Cennamo
PURPOSE: To describe functional and histopathological findings after macular peeling using different dyes. METHODS: Prospective, randomized, comparative, interventional, and immunohistochemical study. Forty-five eyes from 45 patients with idiopathic epiretinal membrane (ERM) underwent pars plana chromovitrectomy with ERM and inner limiting membrane (ILM) using trypan blue 0.15% + brilliant blue 0.05% + lutein 2% in group 1 (15 eyes), trypan blue 0.15% + brilliant blue 0...
June 8, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Jingjing Liu, Yiye Chen, Shiyuan Wang, Xiang Zhang, Peiquan Zhao
BACKGROUND: To evaluate inner retinal dimples after peeling of the inner limiting membrane (ILM) for macular holes (lamellar macular hole [LMH] and full-thickness macular hole [FTMH]) via multiple imaging modes of spectral-domain optical coherence tomography (OCT) and to assess their relationship with preoperative vitreoretinal interface conditions. METHODS: The data of 38 eyes in 35 patients who underwent surgery for LMH, and FTMH were retrospectively studied. The presence of postoperative inner retinal dimples was judged by a combination of en face OCT layer images and cross-sectional images...
June 27, 2018: BMC Ophthalmology
Christoph Leisser, Stefan Palkovits, Nino Hirnschall, Marlies Ullrich, Julius Hienert, Hannah Zwickl, Stefan Georgiev, Oliver Findl
PURPOSE: Internal limiting membrane (ILM) flap transposition in surgical repair of macular holes represents a new technique offering good anatomical success rates with large macular holes. The aim of the study was to examine microperimetric outcomes 1 year after ILM flap transposition for surgical repair of macular holes. METHODS: Patients with idi-opathic macular holes scheduled for 23-G pars plana vitrectomy with ILM peeling, ILM flap transposition, and SF6 tamponade were examined in a prospective case series...
June 22, 2018: Ophthalmic Research
Bhuvan Chanana, Garima Kajla, Sudhank Bharti
Glaucoma drainage devices are mostly used for refractory glaucoma. Early postoperative complications include flat anterior chamber, choroidal effusion, and suprachoroidal hemorrhage. An 8-year-old male patient with a prior history of vitreous surgery for traumatic vitreous hemorrhage, presented to us with angle recession glaucoma in his right eye. His intraocular pressure (IOP) was 44 mmHg despite maximum antiglaucoma medication. Ahmed glaucoma valve (AGV) surgery was performed to control his IOP. In the early postoperative period, the patient developed premacular subinternal limiting membrane (ILM) hemorrhage, which did not resolve even after 4 weeks...
May 2018: Oman Journal of Ophthalmology
Leah B Helou, Clark A Rosen, Wei Wang, Katherine Verdolini Abbott
Purpose: Research suggests that abnormal levels of intrinsic laryngeal muscle (ILM) contraction is a potential causal factor in stress-induced voice disorders. This study seeks to characterize the ILM stress response in a cohort of vocally healthy women. Method: The authors used an unblinded, nonrandomized, repeated-measures design. Forty vocally healthy female adults were subjected to a stressful speech preparation task. Measurements of heart rate, blood pressure, trapezius muscle (positive control) activation, and tibialis muscle (negative control) activation were obtained from 37 participants before and during stressor exposure, in a nonvoice and nonspeaking task paradigm, to confirm physiological stress response compared to baseline...
July 13, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
Taku Wakabayashi, Yasushi Ikuno, Nobuhiko Shiraki, Nagakazu Matsumura, Hirokazu Sakaguchi, Kohji Nishida
PURPOSE: The aim of this study was to investigate the efficacy of pars plana vitrectomy with inverted internal limiting membrane (ILM) insertion for macular hole retinal detachment (MHRD) in high myopia. METHODS: We studied 49 eyes of 49 consecutive patients who underwent vitrectomy for MHRD and were followed for more than 12 months postoperatively. Eyes that underwent vitrectomy with inverted ILM insertion from October 2013 to August 2015 were compared with eyes that underwent standard ILM peeling from October 2006 to September 2013...
June 18, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
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