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Noelle E Carlozzi, Phillip A Ianni, Rael T Lange, Tracey A Brickell, Michael A Kallen, Elizabeth A Hahn, Louis M French, David Cella, Jennifer A Miner, David S Tulsky
OBJECTIVE: To examine the reliability and validity of the short form (SF) and computer adaptive test (CAT) versions of the Patient Reported Outcomes Measurement Information System (PROMIS) measures of social health of caregivers of civilians and service members/veterans (SMVs) with traumatic brain injury (TBI). DESIGN: Self-report questionnaires administered through an on-line data collection platform. SETTING: Hospital and community-based outreach at three TBI Model Systems rehabilitation hospitals, an academic medical center, and a military medical treatment facility PARTICIPANTS: 560 (344 civilians and 216 military) caregivers of individuals with a documented TBI INTERVENTION: N/A MAIN OUTCOME MEASURES: 5 PROMIS Social Health Measures RESULTS: All five PROMIS social health measures exceeded the a priori criterion for internal consistency reliability (≥ 0...
July 31, 2018: Archives of Physical Medicine and Rehabilitation
Karsten Wolter, Georges Decker, Daniel Kuetting, Jonel Trebicka, Steffen Manekeller, Carsten Meyer, Hans Schild, Daniel Thomas
BACKGROUND: Acute portal vein thrombosis is a potentially fatal condition. In symptomatic patients not responding to systemic anticoagulation, interventional procedures have emerged as an alternative to surgery. This study sought to retrospectively evaluate initial results of interventional treatment of acute portal vein thrombosis (aPVT) using a transjugular interventional approach. MATERIALS AND METHODS: Between 2014 and 2016, 11 patients were treated because of aPVT (male: 7; female: 4; mean age: 41...
August 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
Agnieszka Ścibior, Agnieszka Adamczyk, Dorota Gołębiowska, Joanna Kurus
The impact of vanadium (V) and magnesium (Mg) as sodium metavanadate (SMV, 0.125 mg V/ml) and magnesium sulfate (MS, 0.06 mg Mg/ml) on lipid peroxidation (LPO) and selected elements in the rat erythrocytes (RBCs) was investigated. Relationships between some indices determined in RBC were also studied. SMV alone (Group II) elevated the malondialdehyde level (MDARBC ) (by 95% and 60%), compared with the control (Group I) and MS-supplemented rats (Group III), respectively, reduced the concentration of CuRBC (by 23...
July 18, 2018: Chemico-biological Interactions
Yunqiang Cai, Yongbin Li, Pan Gao, Xin Wang, Bing Peng
It is technical challenging to perform laparoscopic pancreaticoduodenectomy (LPD) with major venous resection. Herein, we reported the first case of LPD with major venous resection and reconstruction with repassed round ligament. Between November 2015 and January 2018, a total of 35 LPD with major venous resection were performed in our department; however, only one patient underwent LPD with major venous resection and reconstruction with repassed round ligament. The patient suffered from pancreatic ductal adenocarcinoma with superior mesenteric vein and portal vein (SMV/PV) involvement...
June 2018: Annals of Translational Medicine
Traian Dumitrascu, Alexandru Martiniuc, Vladislav Brasoveanu, Cezar Stroescu, Leonard David, Simona Dima, Oana Stanciulea, Mihnea Ionescu, Irinel Popescu
Introduction: Invasion of portal vein (PV)/ superior mesenteric vein (SMV) in pancreatic ductal adenocarcinoma (PDAC) is no longer a contraindication for resection when reconstruction is technically feasible. However, the literature data reached conflicting conclusions regarding the early and long-term outcomes of patients with venous resection and pancreatectomies for PDAC. The study aims to present the outcomes in a large series of patients with pancreatectomies and associated PV/ SMV resection for PDAC, in a single center experience...
May 2018: Chirurgia
Ifukibot Levi Usende, Chibuisi G Alimba, Benjamin O Emikpe, Adekunle A Bakare, James Olukayode Olopade
Pollution of environment due to increased exploitation of minerals has been on the rise, and vanadium, a metal in the first transition series essential for mammalian existence, is a major component of air pollution. This study investigated the clinico-pathological, hepato-renal toxicity, and cytogenotoxicity of intraperitoneal exposure of African giant rats (AGRs), a proposed model for ecotoxicological research to sodium metavanadate. A total of 27 adult male African giant rats weighing 975 ± 54.10 g were distributed into two major groups: sodium metavanadate (SMV) treated and control...
July 6, 2018: Environmental Science and Pollution Research International
Giovanni Battista Gaeta, Alessio Aghemo, Barbara Menzaghi, Gianpiero D'Offizi, Alessia Giorgini, Hamid Hasson, Giuseppina Brancaccio, Maria Palma, Roberta Termini
The combination of the direct-acting antivirals, simeprevir (SMV) and sofosbuvir (SOF), was the first highly efficacious interferon-free combination for treating patients with hepatitis C virus (HCV), and was widely used in Italy as a result.The aim of this study was to evaluate effectiveness and safety of SMV in Italian patients with HCV genotype (GT) 1 and 4 overall, by treatment regimen [SMV/SOF and SMV/SOF+ribavirin (RBV)], cirrhosis status, and GT (GT1a, GT1b, and GT4).An observational multicenter cohort study was conducted in 46 centers across Italy...
July 2018: Medicine (Baltimore)
Yingliang Qiu, Yingmei Jia, Huasong Cai, Ziping Li, Chenyu Song, Shiting Feng
OBJECTIVE: To compare the difference of the diameters of superior mesenteric vein (SMV) and gastrocolic trunk (GCT) between patients with cecum-ascending colon cancer and normal individuals, and to assess the diagnostic value of the diameters of SMV and GCT in cecum-ascending colon cancer. METHODS: Preoperative imaging data of 60 patients with primary cecum-ascending colon cancer confirmed by postoperative pathology at the First Affiliated Hospital of Sun Yat-sen University from June 2014 to December 2016 were retrospectively analyzed...
June 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Christian Manzardo, Maria C Londoño, Lluis Castells, Milagros Testillano, José Luis Montero, Judit Peñafiel, Marta Subirana, Ana Moreno, Victoria Aguilera, María Luisa González-Diéguez, Jorge Calvo-Pulido, Xavier Xiol, Magdalena Salcedo, Valentin Cuervas-Mons, José Manuel Sousa, Francisco Suarez, Trinidad Serrano, Jose Ignacio Herrero, Miguel Jiménez, José R Fernandez, Carlos Giménez, Santos Del Campo, Juan I Esteban-Mur, Gonzalo Crespo, Asunción Moreno, Gloria de la Rosa, Antoni Rimola, Jose M Miro
Direct-acting antivirals have proved to be highly efficacious and safe in monoinfected liver transplant (LT) recipients who experience recurrence of hepatitis C virus (HCV) infection. However, there is a lack of data on effectiveness and tolerability of these regimens in HCV/HIV-coinfected patients who experience recurrence of HCV infection after LT. In this prospective, multicenter cohort study, the outcomes of 47 HCV/HIV-coinfected LT patients who received DAAs therapy (with or without ribavirin [RBV]) were compared with those of a matched cohort of 148 HCV-monoinfected LT recipients who received similar treatment...
July 2, 2018: American Journal of Transplantation
S F Murphy, M Durand, J P McMorrow, J F Meaney, M Guiney
We present the case of a 71-year-old lady with a background of significant alcohol intake who presented with frank lower gastrointestinal (GI) bleeding, lower abdominal pain and haemoglobin 6.3g/dL. CT abdominal angiogram showed right-sided colonic thickening, atrophic liver and enlarged superior mesenteric vein (SMV) and right-sided pelvic varix. This lead to a diagnosis of portal hypertensive colopathy secondary to alcoholic liver cirrhosis. The patient failed conservative management and underwent a Transjugular Intrahepatic Portosystemic Shunt (TIPSS) procedure...
February 9, 2018: Irish Medical Journal
Hui Li, Xiaoxia Liu, Xiaoming Liu, J P Michaud, Haijian Zhi, Kai Li, Xiangrui Li, Zhen Li
Coevolutionary interactions between pathogens and their insect vectors can dramatically impact the fitness of herbivorous insects and patterns of plant disease transmission. Soybean mosaic virus (SMV) is a common disease in soybean production worldwide. Infected seed is the primary source of inoculum in fields and the virus is secondarily spread among plants by the soybean aphid, Aphis glycines Matsumura (Hemiptera: Aphididae), in a nonpersistent manner. In this study, we compared the biological fitness of A...
June 26, 2018: Journal of Economic Entomology
Mian Wu, Wen-Ping Wu, Cheng-Chen Liu, Ying-Na Liu, Xiao-Yi Wu, Fang-Fang Ma, An-Qi Zhu, Jia-Yin Yang, Bin Wang, Jian-Qun Chen
In the soybean cultivar Suweon 97, BCMV-resistance gene was fine-mapped to a 58.1-kb region co-localizing with the Soybean mosaic virus (SMV)-resistance gene, Rsv1-h raising a possibility that the same gene is utilized against both viral pathogens. Certain soybean cultivars exhibit resistance against soybean mosaic virus (SMV) or bean common mosaic virus (BCMV). Although several SMV-resistance loci have been reported, the understanding of the mechanism underlying BCMV resistance in soybean is limited. Here, by crossing a resistant cultivar Suweon 97 with a susceptible cultivar Williams 82 and inoculating 220 F2 individuals with a BCMV strain (HZZB011), we observed a 3:1 (resistant/susceptible) segregation ratio, suggesting that Suweon 97 possesses a single dominant resistance gene against BCMV...
June 16, 2018: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
H Pott-Junior, G Bricks, G Grandi, J Figueiredo Senise, A Castelo Filho
OBJECTIVE: To investigate the efficacy and safety of sofosbuvir (SOF) plus daclatasvir (DCV) or simeprevir (SMV) in a randomized, open-label, noninferiority trial of patients infected with hepatitis C virus genotype 1, who were previously unresponsive to pegylated interferon and ribavirin or were treatment naive. METHODS: Patients were randomly assigned to receive SOF (400 mg once daily) plus DCV (60 mg once daily) or SMV (150 mg once daily) for 12 weeks. The analysis included all participants who received at least one dose of the study drugs...
June 12, 2018: Clinical Microbiology and Infection
Run-Chen Miao, Yong Wan, Xiao-Gang Zhang, Xing Zhang, Yan Deng, Chang Liu
A 61-year-old female patient with chronic hepatitis B virus infection was diagnosed with liposarcoma in a community hospital. Fine needle aspiration biopsy confirmed the diagnosis of well-differentiated liposarcoma. Abdominal computed tomographic angiography (CTA) showed that the mass adhered to and constricted the main trunk and branch of the superior mesenteric vein (SMV), especially the ileocolic vein, and collateral circulation was observed during the vascular reconstruction scan. The abdominal liposarcoma was resected...
June 14, 2018: World Journal of Gastroenterology: WJG
Hirohito Kan, Nobuyuki Arai, Masahiro Takizawa, Kazuyoshi Omori, Harumasa Kasai, Hiroshi Kunitomo, Yasujiro Hirose, Yuta Shibamoto
PURPOSE: We developed a non-regularized, variable kernel, sophisticated harmonic artifact reduction for phase data (NR-VSHARP) method to accurately estimate local tissue fields without regularization for quantitative susceptibility mapping (QSM). We then used a digital brain phantom to evaluate the accuracy of the NR-VSHARP method, and compared it with the VSHARP and iterative spherical mean value (iSMV) methods through in vivo human brain experiments. MATERIALS AND METHODS: Our proposed NR-VSHARP method, which uses variable spherical mean value (SMV) kernels, minimizes L2 norms only within the volume of interest to reduce phase errors and save cortical information without regularization...
June 15, 2018: Magnetic Resonance Imaging
Yangyu Fan, Jianshu Wang, Rui Du, Guoyun Lv
Fourth-order cumulants (FOCs) vector-based direction of arrival (DOA) estimation methods of non-Gaussian sources may suffer from poor performance for limited snapshots or difficulty in setting parameters. In this paper, a novel FOCs vector-based sparse DOA estimation method is proposed. Firstly, by utilizing the concept of a fourth-order difference co-array (FODCA), an advanced FOCs vector denoising or dimension reduction procedure is presented for arbitrary array geometries. Then, a novel single measurement vector (SMV) model is established by the denoised FOCs vector, and efficiently solved by an off-grid sparse Bayesian inference (OGSBI) method...
June 4, 2018: Sensors
Sadaf Batool, Awais Amjad Malik, Hassaan Bari, Irfan Ul Islam, Faisal Hanif
Option for borderline resectable pancreatic cancer is pancreaticoduodenectomy (PD) with vascular resection and reconstruction. We would like to share our experience of vascular reconstruction. First patient was a 51-year male with pancreatic head carcinoma, involving posterior wall of portal vein (PV) and replacing right hepatic artery (RHA). Along with PD, he underwent PV and RHA resection and reconstruction. Second case was a 33-year female who had distal pancreatic cyst and PV-splenic vein junction involved by tumor...
June 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Jens Brøndum Frøkjær, Weronika Nyholm Jensen, Gitte Holt, Halgurd Khalid Omar, Søren Schou Olesen
PURPOSE: A reliable and immediate diagnosis of internal hernia is important for optimal and timely management of patients with a history of gastric bypass surgery. The aims of this study were to evaluate the interrater agreement and diagnostic performance characteristics of seven predefined CT findings of internal herniation in patients admitted on clinical suspicion of internal herniation after laparoscopic Roux-en-Y gastric bypass (LRYGB). METHODS: Abdominal CT scans of 117 patients performed on clinical suspicion of internal hernia after LRYGB surgery were evaluated by three radiologists (two experts and one resident) for the following: (1) Swirl sign, (2) strangulation of superior mesenteric vein (SMV), (3) engorged mesenteric vessels and edema, (4) engorged lymph nodes, (5) ascites, (6) mushroom sign, (7) hurricane eye sign, and finally the overall conclusion...
May 29, 2018: Abdominal Radiology
E Vicente, Y Quijano, B Ielpo, H Duran
BACKGROUND: Pancreatectomy for locally advanced adenocarcinoma affecting the superior mesenteric artery (SMA) and superior mesenteric vein (SMV) is still under discussion [1]. However, in selected cases, in light of the advancement of recent neoadjuvant treatments, it must be taken into account [2,3]. This video demonstrates some of the technical aspects of SMA and SMV resection as well as some tips of vascular reconstruction. METHODS: A 48-year-old man with a large adenocarcinoma of the uncinated process affecting the SMA and SMV underwent 3 cycles of gemcitabine and nab-paclitaxel neoadjuvancy...
September 2017: Surgical Oncology
Karen You, Mahir Gachabayov, Jens Marius Nesgaard, Jela Bandovic, Dejan Ignjatovic, Arne Bakka, Roberto Bergamaschi
BACKGROUND: D3 extended mesenterectomy (D3EM) for right colon cancer has received increased attention owing to suggested improvement of oncological outcomes. The aim of this study was to evaluate the proficiency-based progression of content-valid metrics in a cadaveric model for right colectomy with D3EM. MATERIALS AND METHODS: Three expert surgeons were enrolled. Surgeon one performed the procedure robotically and surgeons two and three performed open D3EM. Proficiency-based progression was recorded for eight content-valid outcomes...
June 1, 2018: Surgical Technology International
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