Anup Katheria, Jeff Szychowski, Waldemar A Carlo, Akila Subramaniam, Frank Reister, Jochen Essers, Farha Vora, Courtney Martin, Georg M Schmölzer, Brenda Law, Eugene Dempsey, Keelin O'Donoghue, Joseph Kaempf, Mark Tomlinson, Kevin Fulford, Bergen Folsom, Simon Karam, Rachael Morris, Toby Yanowitz, Stacy Beck, Erin Clark, Tara DuPont, Manoj Biniwale, Rangasamy Ramanathan, Shazia Bhat, Matthew Hoffman, Nitin Chouthai, Fayez Bany-Mohammed, Janardhan Mydam, Vivek Narendran, Fiona Wertheimer, Yvonne Gollin, Yvonne Vaucher, Kathy Arnell, Michael Varner, Gary Cutter, Nicole Wilson, Wade Rich, Neil Finer
OBJECTIVES: To determine whether rate of severe intraventricular hemorrhage (IVH) or death among preterm infants receiving placental transfusion with UCM is noninferior to delayed cord clamping (DCC). METHODS: Noninferiority randomized controlled trial comparing UCM versus DCC in preterm infants born 28 to 32 weeks recruited between June 2017 through September 2022 from 19 university and private medical centers in 4 countries. The primary outcome was Grade III/IV IVH or death evaluated at a 1% noninferiority margin...
December 1, 2023: Pediatrics