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sexual transmitted infection

Mariana Santos Felisbino-Mendes, Thayane Fraga de Paula, Ísis Eloah Machado, Maryane Oliveira-Campos, Deborah Carvalho Malta
OBJECTIVE: To analyze sexual and reproductive health indicators of adolescents based on data from the National School-based Health Survey (PeNSE) in 2015, comparing them to the data from 2009 and 2012. METHODS: Cross-sectional study that has analyzed data from 9th grade students from PeNSE 2015, 2012 and 2009. We estimated prevalence and 95% confidence intervals for the following indicators: sexual initiation, condom use in the last sexual intercourse, counseling for pregnancy, sexually transmitted infections and free condoms in the three rounds of the survey...
November 29, 2018: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
Ian H Spicknall, Kenneth H Mayer, Sevgi O Aral, Ethan O Romero-Severson
BACKGROUND: Increased gonorrhea detection highlights the need for additional prevention efforts. Gonorrhea may only be acquired when there is contact between infected and uninfected anatomical sites. With three sites of infection this leads to seven plausible routes of MSM transmission: urethra-to-rectum, rectum-to-urethra, urethra-to-oropharynx, rectum-to-oropharynx, oropharynx-to-urethra, oropharynx-to-rectum, and oropharynx-to-oropharynx. We characterize the uncertainty and potential importance of transmission from each anatomical site using a deterministic compartmental mathematical model...
December 3, 2018: Sexually Transmitted Diseases
Gianna T Le, Julianna Deardorff, Maureen Lahiff, Kim G Harley
PURPOSE: Research on parental incarceration and the health of offspring is relatively scarce despite studies linking childhood adverse experiences to a range of physical and mental health conditions. This study aimed to estimate the associations between parental incarceration and sexual risk outcomes (early sexual onset, inconsistent condom use, and sexually transmitted infections [STIs]) in young adulthood. METHODS: We used logistic regression to estimate associations of sexual risk taking behaviors with parental incarceration during childhood in a sample of 3,972 participants in The National Longitudinal Study of Adolescent to Adult Health (Add Health) between 2001 and 2009...
December 1, 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
Steven Maxwell, Maryam Shahmanesh, Mitzy Gafos
BACKGROUND: 'Chemsex' is the use of drugs before or during planned sexual events to facilitate, enhance, prolong and sustain the experience. Drugs associated with chemsex are methamphetamine, GHB/GBL, mephedrone, cocaine and ketamine. This review syntheses published research on the antecedents, behaviours and consequences associated with chemsex behaviours among men who have sex with men (MSM). METHODS: Papers from high income countries which were published between January 2000 and September 2018 reporting the use of chemsex drugs before or during sex were identified through Medline, Web of Science, CINAHL and Central...
December 1, 2018: International Journal on Drug Policy
Priya Sharma, Kamnoosh Shahabi, Rachel Spitzer, Michele Farrugia, Rupert Kaul, Mark Yudin
In a prospective study of twenty sexually transmitted infection (STI)-free women, we examined the impact of an intrauterine contraceptive device (IUCD) insertion on cervico-vaginal cytokine levels. Nine women chose the levonorgestrel-containing IUCD and eight chose a copper IUCD. A cervico-vaginal swab was collected for cytokine analysis pre-insertion and four weeks post-insertion. Significant increases were noted in levels of IL-1α (median 483.4 versus 316.6 pg/mL, p = 0.046), IL-1β (median 605.7 versus 147...
2018: PloS One
David L Rodrigues, Diniz Lopes, Marco Pereira, Marília Prada, Margarida V Garrido
Despite recurrent efforts to prevent sexually transmitted diseases through the use of condoms, HIV infections are still prevalent across Europe. Recent research framed by the regulatory focus theory has shown that prevention (vs. promotion)-focused individuals are more likely to adopt strategies to protect their health. Therefore, these individuals should also be more motivated to use condoms, because they are more likely to perceive greater health threats. In two cross-sectional preregistered studies (combined N = 520 Portuguese participants; databases available at https://doi...
December 3, 2018: Archives of Sexual Behavior
Farzaneh Ghassabi, Yalda Malekzadegan, Hadi Sedigh Ebrahim-Saraie, Hamid Heidari, Mozhgan Sabet, Abdollatif Bagheri, Narges Bagheri, Hadi Raeisi Shahraki, Alireza Hasanabadi, Mohammad Motamedifar
Background: Neisseria gonorrhea and Treponema pallidum as an obligate human pathogen are two common causes of sexually transmitted diseases (STDs). The present study aimed to determine the prevalence of N. gonorrhoeae and T. pallidum among human immunodeficiency virus (HIV) patients in the southwest Iran. Methods: This retrospective study was performed from 2004 to 2013, on HIV patients who were tested for detection of gonorrhea and syphilis infection at Shiraz HIV/AIDS Research Center...
2018: Caspian Journal of Internal Medicine
Louise A Rohrbach, Robin A Donatello, Bret D Moulton, Abdelmonem A Afifi, Kristin I Meyer, Christine J De Rosa
PURPOSE: This study assessed the effectiveness of the HIV/sexually transmitted infection/pregnancy prevention program, It's Your Game: Keep It Real (IYG). METHODS: IYG was implemented by classroom teachers in 24 urban middle schools from 2012 to 2015. Using a quasi-experimental design, each year we surveyed ninth-grade students in 10 high schools that were selected based on feeder patterns from project middle schools. We compared two groups of students (n = 4,562): (1) students whose middle school grade cohorts did not receive IYG ("No-IYG"), and (2) students whose middle school grade cohorts received IYG ("IYG")...
November 30, 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
Adi Nugroho, Robert W S Coulter, Vicki Erasmus, Pipiet A Laksmono, Tengku S Mihari, Jan Hendrik Richardus
Implementers of outreach program in Indonesia often provide formal training for their outreach workers (OWs) only at the startup. We believe continuous training can be provided by experienced OWs at any time if an appropriate training package is available. Using a one-group pre-test-post-test study design; we developed, implemented and evaluated an OW-informed training program aimed at increasing OWs' knowledge and skills for outreaching to men who have sex with men and transgender women. We analyzed longitudinal data from 75 OWs from 7 Indonesian cities using one-way within-subjects ANOVA to examine the effects of the training program on participants' knowledge and perceived skills over time Average overall knowledge among participants increased from pre-test to immediate post-test (P < 0...
December 1, 2018: Health Education Research
Ricardo Niklas Werner, Matthew Gaskins, Alexander Nast, Corinna Dressler
BACKGROUND: Men who have sex with men (MSM) and who engage in condomless anal intercourse with casual partners are at high risk of acquiring sexually transmitted infections (STIs), but reliable epidemiological data are scarce. Studies on HIV pre-exposure prophylaxis (PrEP) enrol MSM who indicate that they engage in behaviour that puts them at high risk of acquiring HIV. Because they also screen for STIs at regular intervals, these studies may serve as a valuable source to estimate incidence rates of STIs in this subpopulation of MSM...
2018: PloS One
Henry J C de Vries
PURPOSE OF REVIEW: Lymphogranuloma venereum (LGV) is a serious sexually transmitted infection caused by Chlamydia trachomatis. If left untreated LGV can cause irreversible late sequelae. LGV is endemic among a high-risk population of men who have sex with men (MSM), and largely reported in Western metropoles. RECENT FINDINGS: Although the majority of LGV patients are HIV positive, in recent years the proportion of HIV-negative MSM with LGV is rising. This could indicate a shift toward lower risk populations...
November 30, 2018: Current Opinion in Infectious Diseases
Emma Linton, Lisa Hardman, Lynn Welburn, Imran Rahman, Jaya Devi Chidambaram
Purpose: Although Chlamydia trachomatis and Neisseria gonorrhoeae are the commonest sexually transmitted infections in England, reports of ocular co-infection in the literature are limited. We report such a case which responded well to treatment, and discuss the literature and evidence currently available with regards to management of these cases. Observations: The patient is a 48-year-old bisexual gentleman who presented to the eye clinic of a UK hospital with redness, discharge and blurred vision in his left eye for one week...
March 2019: American Journal of Ophthalmology Case Reports
Brian A Feinstein, Trey V Dellucci, Simon Graham, Jeffrey T Parsons, Brian Mustanski
Despite high rates of sexually transmitted infections (STIs) among young men who have sex with men (YMSM), little is known about their experiences with diagnosis, treatment, and reinfection. To fill this gap, we interviewed 17 YMSM ages 18-29 who participated in an online HIV prevention trial and tested positive for STIs at both the baseline and three-month follow-up assessments. Participants were asked about their reactions to testing positive, experiences with treatment, disclosure to partners, and changes in thinking and behavior...
June 2018: Sexuality Research & Social Policy
Krishna Talukdar, Ajay Chopra, Debdeep Mitra, Barnali Mitra
Background: Sexually transmitted infections (STIs) have a definite role in the facilitation of HIV infection, which, in turn, also increases susceptibility to other STIs. Further, the social stigma and secrecy surrounding STIs create difficulty in estimating its true incidence and prevalence. Objective: The objective of this study was to know the pattern of diseases including different clinical presentations and final diagnosis among the STI clinic attendees. Materials and Methods: This study was a hospital-based study; a predesigned and pretested schedule was used to collect data from 140 patients after obtaining their consent...
November 2018: Indian Journal of Dermatology
Ishita Ghosh, Bandhan Paul, Nibedita Das, Debabrata Bandyopadhyay, Manas Kumar Chakrabarti
Context: Sexually transmitted infections (STIs) and reproductive tract infections (RTIs) constitute important public health problem worldwide. Syndromic diagnosis of vaginal/cervical discharge (VCD) is often inaccurate leading to over- or under-treatment. Aims: This study aimed to ascertain the laboratory-confirmed diagnosis of VCD and their relative frequency in a group of patients presenting to a STI clinic in eastern India and to determine the sensitivity and specificity of clinical diagnosis...
November 2018: Indian Journal of Dermatology
Rani Mathew, Bangalath Najeem, Kunjumani Sobhanakumary, Beena Sunny, Carol Pinheiro, Balakrishnan Anukumar
Background: Herpes genitalis is an ulcerating sexually transmitted infection, the clinical importance of which lies in its ability to produce painful and recurrent disease in addition to its potential role as a cofactor in acquisition and transmission of human immunodeficiency virus. In recent years, there are increasing reports of genital herpes due to herpes simplex virus (HSV)-1 from various parts of the world. Molecular diagnostic methods such as polymerase chain reaction (PCR) have got both diagnostic and prognostic significance in genital herpes...
November 2018: Indian Journal of Dermatology
Swastika Suvirya, Mukesh Shukla, Sucheta Pathania, Gopa Banerjee, Ajit Kumar, Adarsh Tripathi
Context: Illnesses affecting sexual organs and its correlation with improper sexual behavior lead to a negative attitude and discriminating behavior towards people affected by such disorders. Aim: The aim was to study the stigma associated with sexually transmitted infections (STIs) among patients attending Suraksha clinic at a tertiary care hospital in northern India. Settings and Design: This was a hospital-based cross-sectional study. Subjects and Methods: The present study was conducted at Suraksha (STI) clinic, King George's Medical University, Uttar Pradesh...
November 2018: Indian Journal of Dermatology
Anna Månberg, Frideborg Bradley, Ulrika Qundos, Brandon L Guthrie, Kenzie Birse, Laura Noël-Romas, Cecilia Lindskog, Rose Bosire, James Kiarie, Carey Farquhar, Adam D Burgener, Peter Nilsson, Kristina Broliden
Women at high risk of HIV infection, including sex workers and those with active genital inflammation, have molecular signatures of immune activation and epithelial barrier remodeling in samples of their genital mucosa. These alterations in the local immunological milieu are likely to impact HIV susceptibility. We here analyze host genital protein signatures in HIV uninfected women, with high frequency of condom use, living in HIV-serodiscordant relationships. Cervicovaginal secretions from women living in HIV-serodiscordant relationships (n=62) were collected at three time points over 12 months...
November 30, 2018: Molecular & Cellular Proteomics: MCP
Stephanie E Cohen, Darpun Sachdev, Sulggi A Lee, Susan Scheer, Oliver Bacon, Miao-Jung Chen, Hideaki Okochi, Peter L Anderson, Mary F Kearney, Susa Coffey, Hyman Scott, Robert M Grant, Diane Havlir, Monica Gandhi
BACKGROUND: Pre-exposure prophylaxis (PrEP) with emtricitabine and tenofovir disoproxil fumarate is highly protective against HIV infection. We report a case of tenofovir-susceptible, emtricitabine-resistant HIV acquisition despite high adherence to daily PrEP. METHODS: Adherence to PrEP was assessed by measuring concentrations of emtricitabine and tenofovir disoproxil fumarate or their metabolites in plasma, dried blood spots, and hair. After seroconversion, genotypic and phenotypic resistance of the acquired virus was determined by standard clinical tests and by single-genome sequencing of proviral genomes...
November 29, 2018: Lancet HIV
Laurent Hébert, Edouard Guitton, Anthony Madeline, Tristan Géraud, Stéphan Zientara, Claire Laugier, Aymeric Hans, Philippe Büscher, Julien Cauchard, Sandrine Petry
The aim of this study was to evaluate the ability of melarsomine hydrochloride (Cymelarsan® ) to cure horses suffering from a nervous form of dourine, a sexually-transmitted disease caused by Trypanosoma equiperdum. The recently described experimental model for assessing drug efficacy against horse trypanosomosis allowed us to obtain eight horses (Welsh pony mares) infected by T. equiperdum with parasites in their cerebrospinal fluid. The Cymelarsan® treatment evaluated consisted of the daily administration of 0...
December 15, 2018: Veterinary Parasitology
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