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https://www.readbyqxmd.com/read/30526921/femoral-neck-fractures-after-internal-fixation-of-trochanteric-fractures-with-implants-in-situ-in-adults-a-systematic-review
#1
Antonio Barquet, Peter V Giannoudis, Andrés Gelink
INTRODUCTION: Femoral neck fractures (FNF) after internal fixation of trochanteric fractures (AIFTF) with the implant in situ (WIIS) are uncommon. Publications of FNFAIFTFWIIS are rare. The purpose of this systematic review of the literature is to report on the frequency, risk factors, mechanisms, clinical presentation, diagnostic and therapeutic modalities, outcomes and the eventual prevention of this complication. MATERIALS AND METHODS: A comprehensive review of the literature was undertaken using the PRISMA guidelines with no language restriction...
December 2018: Injury
https://www.readbyqxmd.com/read/30505650/muscle-and-bone-mass-loss-in-the-elderly-population-advances-in-diagnosis-and-treatment
#2
Carlos J Padilla Colón, Irma L Molina-Vicenty, María Frontera-Rodríguez, Alejandra García-Ferré, Bernabejoel Ponce Rivera, Gerardo Cintrón-Vélez, Sebastián Frontera-Rodríguez
Aging is the result of different functional changes leading to a substantial reduction of all human capabilities. A variety of anatomical and physiological changes occur with advancing age. These changes are more evident in the elderly population. There are various methods to measure muscle and bone mass loss, but the dual X-ray absorptiometry (DXA) is considered one of the most efficient. The elderly population (65 years and older) has been increasing throughout the years. Loss of muscle mass (sarcopenia) and loss bone mass (osteopenia or osteoporosis) with advancing age, when untreated, represent a major public health problem for the elderly population and may result in loss of independence in later life...
2018: Journal of Biomedicine
https://www.readbyqxmd.com/read/30503353/exercise-for-the-prevention-of-osteoporosis-in-postmenopausal-women-an-evidence-based-guide-to-the-optimal-prescription
#3
REVIEW
Robin M Daly, Jack Dalla Via, Rachel L Duckham, Steve F Fraser, Eva Wulff Helge
BACKGROUND: Osteoporosis and related fragility fractures are a global public health problem in which pharmaceutical agents targeting bone mineral density (BMD) are the first line of treatment. However, pharmaceuticals have no effect on improving other key fracture risk factors, including low muscle strength, power and functional capacity, all of which are associated with an increased risk for falls and fracture, independent of BMD. Targeted exercise training is the only strategy that can simultaneously improve multiple skeletal and fall-related risk factors, but it must be appropriately prescribed and tailored to the desired outcome(s) and the specified target group...
November 22, 2018: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/30481576/self-reported-low-energy-fractures-and-associated-risk-factors-in-people-with-diabetes-a-national-population-based-study
#4
Sofia Furtado, Ana Rodrigues, Sara Dias, Jaime C Branco, Helena Canhão
AIMS: Clinical risk factors and bone mineral densitometry underestimate low-energy fracture (LEF) risk in people with diabetes. We aim to estimate the prevalence of LEF in diabetics, compare with nondiabetics; and evaluate possible predictors of LEF in people with diabetes. METHODS: Cross-sectional, population-based study in Portuguese subjects over 40 years-old. Estimates computed as weighted proportions/means, considering sample design. Multivariate logistic regression models to evaluate the association of diabetes and LEF; and predictors of LEF in diabetics...
November 24, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/30474461/predictors-of-pre-sarcopenia-in-community-dwelling-older-adults-a-5-year-longitudinal-study
#5
Kazuyoshi Kobayashi, Kei Ando, Mikito Tsushima, Masaaki Machino, Kyotaro Ota, Masayoshi Morozumi, Satoshi Tanaka, Shunsuke Kanbara, Naoki Ishiguro, Yukiharu Hasegawa, Shiro Imagama
OBJECTIVES: Sarcopenia is an aging-induced decrease in muscle mass that increases frailty and fall in elderly people. Pre-sarcopenia corresponds to the preliminary stage of sarcopenia. The purpose of this prospective study is to examine predictors of pre-sarcopenia in health screening. METHODS: The subjects were 124 community residents aged ≥60 years (55 males, 69 females, average age 70.2 years) who attended local government health checkups in 2010 and 2015, as part of the Yakumo study, and did not have pre-sarcopenia in 2010...
November 24, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/30474449/study-description-and-baseline-characteristics-of-the-population-enrolled-in-a-multinational-observational-study-of-teriparatide-in-postmenopausal-women-with-osteoporosis-the-asia-and-latin-america-fracture-observational-study-alafos
#6
Chung-Hwan Chen, Abdulaziz H Elsalmawy, Sophia Ish-Shalom, Seung-Jae Lim, Nadia S Al-Ali, Joao L Cunha-Borges, Huilin Yang, Noemí Casas, Lale Altan, Thomas Moll, Sirel Gurbuz, Alan J M Brnabic, Russel T Burge, Fernando Marin
OBJECTIVE: To describe the study design and baseline patient characteristics of the Asia and Latin America Fracture Observational Study (ALAFOS) to better understand the profile of patients receiving teriparatide during the course of routine clinical practice in Asia, Latin America, the Middle East, and Russia. METHODS: Prospective, observational, non-interventional study in postmenopausal women with osteoporosis who are prescribed teriparatide for up to 24 months, according to local medical standards, with a 12-month post-treatment follow-up...
November 25, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/30471719/-osteosarcopenia-a-narrative-review
#7
REVIEW
Bernardo Cedeno-Veloz, Pedro López-Dóriga Bonnardeauxa, Gustavo Duque
Osteosarcopenia is a phenotype resulting from the combination of sarcopenia and low bone mineral density. Based on the relationship between bone and muscle, this phenotype is associated with a higher risk of falls, fractures, dependence, and health care costs than its individual components. Given its characteristics, it can be considered as a new geriatric syndrome. Therefore, understanding its pathophysiology and diagnosis, as well as its non-pharmacological and pharmacological management is a task of great importance...
November 21, 2018: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/30417253/a-systematic-review-of-factors-affecting-medication-adherence-among-patients-with-osteoporosis
#8
REVIEW
C T Yeam, S Chia, H C C Tan, Y H Kwan, W Fong, J J B Seng
The aim of this review was to identify factors that influence patients' adherence to anti-osteoporotic therapy. Factors identified that were associated with poorer medication adherence included polypharmacy, older age, and misconceptions about osteoporosis. Physicians need to be aware of these factors so as to optimize therapeutic outcomes for patients. INTRODUCTION: To identify factors that influence patients' adherence to anti-osteoporotic therapy. METHODS: A systematic review of literature was performed for articles published up till January 2018 using PubMed®, PsychINFO®, Embase®, and CINAHL®...
December 2018: Osteoporosis International
https://www.readbyqxmd.com/read/30407295/breathlessness-in-amyotrophic-lateral-sclerosis-a-case-report-on-the-role-of-osteoporosis-in-the-worsening-of-respiratory-failure
#9
Simona Portaro, Elisabetta Morini, Maria Elena Santoro, Maria Accorinti, Pietro Marzullo, Antonino Naro, Rocco Salvatore Calabrò
RATIONALE: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative multisystem disorder, presenting with limb or bulbar onset. To date, there is no cure for ALS. At some stage of the disease, patients may complain of breathlessness due to respiratory failure, thus needing a noninvasive mechanical ventilation (NIMV) support. However, breathlessness is a symptom that may be induced by different causes that must be taken into consideration in ALS management. PATIENTS CONCERNS: We report the case of an 81-year-old man, with a spinal onset ALS, who was admitted to our clinic to start NIMV because of respiratory involvement...
November 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30369611/rapidly-destructive-arthrosis-of-bilateral-humeral-heads-caused-by-subchondral-insufficiency-fracture
#10
Rika Kakutani, Naoki Kondo, Tomoharu Mochizuki, Junichi Fujisawa, Naoto Endo
The bilateral shoulder pain of an 81-year-old Japanese woman due to falls persisted despite celecoxib treatment, and plain X-rays later showed bilateral collapsed humeral heads. After ruling out osteoarthritis, infectious arthritis, crystal-induced arthritis, neuropathic arthropathy, and osteonecrosis, we diagnosed bilateral shoulder joint rapidly destructive arthrosis (RDA). Lumbar bone mineral density showed very low T-score (-4.1). Primary osteoporosis was observed. Histology of biopsied humeral head indicated the features of fracture healing process: callus formation and osteoclasts without empty lacunae...
October 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/30341848/treatment-of-vitamin-d-deficiency-and-comorbidities-a-review
#11
Parminder Singh
Vitamin D is essential for the maintenance of calcium and phosphorus homeostasis, skeletal growth and various other metabolic processes. The prevalence of vitamin D deficiency in India is 50-90% in various studies. Factors such as low sunlight exposure, age-related decrease in cutaneous synthesis, and low dietary intake of vitamin D contribute to the high prevalence of vitamin D inadequacy which has emerged as a highly pervasive condition. Bone diseases such as rickets in children, osteomalacia and osteoporosis in adults are related with vitamin D insufficiency...
January 2018: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/30324413/patients-with-prostate-cancer-and-androgen-deprivation-therapy-have-increased-risk-of-fractures-a-study-from-the-fractures-and-fall-injuries-in-the-elderly-cohort-frailco
#12
M Wallander, K F Axelsson, D Lundh, M Lorentzon
Osteoporosis is a common complication of androgen deprivation therapy (ADT). In this large Swedish cohort study consisting of a total of nearly 180,000 older men, we found that those with prostate cancer and ADT have a significantly increased risk of future osteoporotic fractures. INTRODUCTION: Androgen deprivation therapy (ADT) in patients with prostate cancer is associated to increased risk of fractures. In this study, we investigated the relationship between ADT in patients with prostate cancer and the risk of incident fractures and non-skeletal fall injuries both compared to those without ADT and compared to patients without prostate cancer...
October 15, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/30311093/the-role-of-the-fracture-liaison-service-fls-in-subsequent-fracture-prevention-in-the-extreme-elderly
#13
Ilknur Sanli, Sven H van Helden, René H M Ten Broeke, Piet Geusens, Joop P W Van den Bergh, Peter R G Brink, Martijn Poeze
BACKGROUND: Several guidelines recommend a bone and fall-related osteoporosis risk assessment in all patients with fracture and age > 50 years. In practice, however, there is no consensus whether screening > 85 years is useful. AIM: To evaluate the subsequent fracture risk in all patient > 85 years, comparing the two populations of Fracture Liaison Service (FLS) attenders and non-attenders. METHODS: All patients > 85 years that presented at the FLS with a non-vertebral fracture were included in the study during a 5-year period (September 2004 and December 2009)...
October 11, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/30310959/prevalence-risk-factors-and-therapeutic-aspects-of-injuries-and-accidents-in-women-with-epilepsy
#14
René Danilo Verboket, Nicolas Söhling, Ingo Marzi, Esther Paule, Susanne Knake, Felix Rosenow, Adam Strzelczyk, Laurent Maximilian Willems
BACKGROUND: Epilepsy-related injuries and accidents (ERIA) are a frequent cause of hospitalisation and represent a relevant burden for patients with epilepsy. In particular, osteoporosis and other gender-specific aspects may increase the risk of seizure-related fractures and injuries in women with epilepsy. AIM AND SCOPE: The aim of this analysis is to determine the prevalence and clinical nature of ERIA in a cohort of women with epilepsy, to identify possible determinants including osteoporosis and to give an overview of the current knowledge of clinically important prophylactic and therapeutic aspects...
October 11, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/30310769/perception-of-peri-menopausal-and-postmenopausal-lebanese-women-on-osteoporosis-a-cross-sectional-study
#15
Hala Ahmadieh, Ahmad Basho, Amal Chehade, Adeeb Al Mallah, Ahmad Dakour
Introduction: Osteoporosis is a generalized skeletal disorder characterized by decreased bone mineral density and microarchitectural deterioration, resulting in increased susceptibility to fractures. The prevalence of osteoporosis in Lebanon, defined as T-score <-2.5 at the total hip using NHANES gender-specific database was estimated to be 31% among postmenopausal women. Purpose: To assess the general perception of osteoporosis among women in Lebanon as well as their general knowledge of its lifestyle, risk factors, diagnostic, preventive and therapeutic measures...
December 2018: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/30298174/association-between-high-levels-of-parathyroid-hormone-and-frailty-the-nepean-osteoporosis-and-frailty-nof-study
#16
L Murthy, P Dreyer, P Suriyaarachchi, F Gomez, C L Curcio, D Boersma, G Duque
BACKGROUND: Frailty is associated with poor outcomes hence identification of risks factors is pivotal. Since the independent role of parathyroid hormone (PTH) in frailty remains unexplored, we aimed to determine this in a population of older individuals with a history of falling. DESIGN: Cross-sectional study. SETTING: Falls and Fracture Clinic, Nepean Hospital (Penrith, Australia). PARTICIPANTS: 692 subjects (mean age=79, 65% women) assessed between 2009-2015...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/30296993/current-imaging-techniques-in-osteoporosis
#17
REVIEW
John J Carey, Bjoern Buehring
Osteoporosis is a global pandemic affecting children, men and women of all ages and ethnicities. Millions of people suffer fragility fractures each year around the world as a result of this bone disease, which can have devastating consequences for them, including permanent disability and death. Many fractures are preventable by identifying people at high risk for fracture and falls, and diagnosing those who already have osteoporosis, before they fracture. Rheumatologists commonly encounter people with fragile bones, either as an isolated entity, or a co-morbidity to their underlying rheumatic illness or treatment...
September 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/30288335/the-community-health-experience-model-value-generation-from-person-centered-health-transaction-network
#18
Zoltán Lantos, Judit Simon
Background: Network society is creating new opportunities for value generation in all areas of our lives: new collaborative methods and tools are increasingly available for use by closely connected individuals and organizations. The stakeholders of the health ecosystem are potential winners of this networking process as a consequence of the increase in knowledge about health value generation supported by teamwork and collaborative approaches in this field. Case Presentation: In this paper, we focus on the transactional nature of health value generation networks...
2018: Public Health Reviews
https://www.readbyqxmd.com/read/30287350/french-recommendations-for-osteoporosis-prevention-and-treatment-in-patients-with-prostate-cancer-treated-by-androgen-deprivation
#19
Karine Briot, Julien Paccou, Philippe Beuzeboc, Jacques Bonneterre, Béatrice Bouvard, Cyrille B Confavreux, Catherine Cormier, Bernard Cortet, Jean-Michel Hannoun-Lévi, Christophe Hennequin, Rose-Marie Javier, Eric Lespessailles, Didier Mayeur, Pierre Mongiat Artus, Marie-Hélène Vieillard, Françoise Debiais
Androgen-deprivation therapy (ADT) in patients with prostate cancer can be achieved surgically or chemically, notably by prescribing LHRH analogs. Major bone loss occurs rapidly in both cases, due to the decrease in testosterone levels, and can increase the fracture risk. The objective of developing these recommendations was to achieve a practical consensus among various scientific societies, based on a literature review, about osteoporosis prevention and treatment in patients on ADT. The following scientific societies contributed to the work: Société Française de Rhumatologie (SFR), Groupe de Recherche et d'Information sur les Ostéoporoses (GRIO), Groupe Européen d'Etudes des Métastases Osseuses (GEMO), Association Francophone pour les SOins de Support (AFSOS), Association Française d'Urologie (AFU), Société Française de Radiothérapie Oncologique (SFRO)...
October 1, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30283610/pharmacological-and-non-pharmacological-means-for-prevention-of-fractures-among-elderly
#20
REVIEW
Auda Fares
Fractures are major cause of morbidity, mortality, and healthcare and social services expenditure in elderly. Fractures often have multifactorial etiologies and the condition emerges due to the interaction between the different predisposing and precipitating factors. One of the most common causes leading to fractures after minimal trauma in older people is osteoporosis. The objective of this article is to describe the clinical concept and summarize the evidence and to explain the future directions for research, focusing on specific issues related to prevent fracture in the elderly...
2018: International Journal of Preventive Medicine
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