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Exercise AND oncology

Kevin T Dyer, Christopher P Hogrefe
Exertional limb pain is a common problem encountered in recreational and competitive athletes. Affecting both the upper and lower extremities, this broad entity can be musculoskeletal, vascular, neurologic, oncologic, or infectious in origin. This article focuses on the vascular causes of exercise-related extremity pain, which encompass a cadre of elusive diagnoses. Specifically, we examine arterial endofibrosis, popliteal artery entrapment syndrome, and chronic exertional compartment syndrome of both the upper and lower extremities...
October 2018: Current Sports Medicine Reports
D Pfirrmann, P Simon, M Mehdorn, M Hänsig, S Stehr, L Selig, A Weimann, M Knödler, F Lordick, A Mehnert, I Gockel
BACKGROUND: Postoperative complications after complex visceral oncological surgery can lead to substantial impairment of patients. In addition, preoperative physical performance and the severity of postoperative complications determine the long-term recovery process of physical function. Therefore, preconditioning in the preoperative period should be an important part of the preoperative/neoadjuvant treatment. OBJECTIVE: The aim of this article is a critical appraisal of current concepts of prehabilitation as well as their development potential and applicability in visceral surgery...
October 2, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
Shirin M Shallwani, Anna Towers
Purpose: Malignant lymphedema is an accumulation of interstitial fluid caused by tumour infiltration or compression of lymphatic vessels. Our objective is to describe self-management strategies for malignant lymphedema using a case report. Client Description: A 50-year-old woman with advanced breast cancer was referred to our centre with a 3-month history of unexplained left-arm edema, subsequently diagnosed as malignant lymphedema caused by tumour compression of the axillary lymph nodes. Intervention: She undertook a physiotherapist-guided, modified lymphedema treatment programme, with self-management interventions including self-bandaging and exercise...
2018: Physiotherapy Canada. Physiothérapie Canada
Marta Kramer Mikkelsen, Cecilia Margareta Lund, Anders Vinther, Anders Tolver, Anne-Mette Ragle, Julia Sidenius Johansen, Inna Chen, Lotte Engell-Noerregaard, Finn Ole Larsen, Bo Zerahn, Dorte Lisbet Nielsen, Mary Jarden
BACKGROUND: Several intervention studies have demonstrated that exercise training has beneficial effects among cancer patients. However, older cancer patients are underrepresented in clinical trials, and only few exercise-based studies have focused specifically on older patients with cancer. In particular, research investigating the effects of exercise training among older patients with advanced cancer is lacking. The purpose of the current study is to investigate the effect of a 12-week multimodal and exercise-based intervention among older patients (≥65 years) with advanced pancreatic, biliary tract or lung cancer, who are treated with first-line palliative chemotherapy, immunotherapy or targeted therapy...
September 27, 2018: BMC Cancer
Amy A Kirkham, Matthew G Lloyd, Victoria E Claydon, Karen A Gelmon, Donald C McKenzie, Kristin L Campbell
BACKGROUND: Cardiovascular autonomic dysfunction is an early marker for cardiovascular disease. Anthracycline chemotherapy and left-sided radiation for breast cancer are associated with negative autonomic function changes. This study's objectives were to characterize changes in, and the association of exercise training with, clinical indices of cardiovascular autonomic function across the trajectory of breast cancer therapy. SUBJECTS, MATERIALS, AND METHODS: Seventy-three patients receiving adjuvant chemotherapy participated to varying degrees in supervised aerobic and resistance exercise during chemotherapy ± radiation and for 20 weeks after...
September 26, 2018: Oncologist
Fiona Crawford-Williams, Sonja March, Belinda C Goodwin, Nicholas Ralph, Daniel A Galvão, Robert U Newton, Suzanne K Chambers, Jeff Dunn
OBJECTIVE: To systematically review the evidence for interventions addressing key domains of the American Cancer Society (ACS) and American Society of Clinical Oncology (ASCO) Prostate Cancer Survivorship Care Guidelines: health promotion, surveillance, physical side effects, psychosocial management, and care coordination. METHODS: We conducted a systematic review of systematic reviews and meta-analyses of interventions targeting ACS/ASCO guideline domains. All titles and abstracts were independently assessed for inclusion based on predetermined criteria...
October 2018: Psycho-oncology
Jazel Sugay
BACKGROUND: The development of biosimilars is occurring more rapidly as patents on biologics expire. Oncology nurses will have an integral role in the new era of biosimilars regarding administration and education. OBJECTIVES: The purpose of this article is to review the role of the oncology nurse during biosimilar clinical trials, including regulatory guidelines, comparability exercise, clinical trial designs, and extrapolation of clinical trial data. This article also reviews pharmacovigilance...
October 1, 2018: Clinical Journal of Oncology Nursing
Gurpreet Kaur, Gaurav Prakash, Pankaj Malhotra, Sandhya Ghai, Sukhpal Kaur, Mahender Singh, Kulbeer Kaur
Background: Yoga is proven beneficial in improving quality of life among breast cancer survivors receiving chemotherapy, but its effectiveness in lymphoma patients needs to be explored. As chemotherapy-induced neutropenia is very common among lymphoma patients, they are much prone to infections from the environment. Furthermore, trained yoga instructors are not available in every setting, so there is a need to develop home-based yoga program modules for lymphoma patients receiving chemotherapy...
September 2018: International Journal of Yoga
Suzanne J Grant, Michael Marthick, Judith Lacey
Comprehensive cancer centres are on the rise as patients seek a more holistic approach to maintaining their wellbeing when living with a cancer diagnosis. Many cancer centres worldwide now incorporate a selection of evidence-based complementary therapies and qualified therapists into their offerings. The Chris O'Brien Lifehouse, a comprehensive cancer centre in Sydney, Australia, provides integrative oncology services including acupuncture, massage, reflexology, dietetics and exercise physiology for individual patients, along with group programmes, and an integrative and supportive care medical specialist...
September 17, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Javier S Morales, Pedro L Valenzuela, Cecilia Rincón-Castanedo, Tim Takken, Carmen Fiuza-Luces, Alejandro Santos-Lozano, Alejandro Lucia
INTRODUCTION: Physical capacity and quality of life (QoL) are typically impaired in children/adolescents with cancer. Our primary objective was to examine the effects of exercise training performed after diagnosis of any type of pediatric cancer on physical capacity-related endpoints, survival, disease relapse and adverse effects. METHODS: (a) Search and selection criteria: Systematic review in Pubmed and Web of Science (until August 2018) of randomized controlled trials (RCTs) of exercise interventions in children with cancer during treatment or within one year after its end...
September 3, 2018: Cancer Treatment Reviews
Kristin Schink, Hans J Herrmann, Raphaela Schwappacher, Julia Meyer, Till Orlemann, Elisabeth Waldmann, Bernd Wullich, Andreas Kahlmeyer, Rainer Fietkau, Dorota Lubgan, Matthias W Beckmann, Carolin Hack, Wolfgang Kemmler, Jürgen Siebler, Markus F Neurath, Yurdagül Zopf
BACKGROUND: Physical exercise and nutritional treatment are promising measures to prevent muscle wasting that is frequently observed in advanced-stage cancer patients. However, conventional exercise is not always suitable for these patients due to physical weakness and therapeutic side effects. In this pilot study, we examined the effect of a combined approach of the novel training method whole-body electromyostimulation (WB-EMS) and individualized nutritional support on body composition with primary focus on skeletal muscle mass in advanced cancer patients under oncological treatment...
September 12, 2018: BMC Cancer
Robert K Cleary, Arden M Morris, George J Chang, Amy L Halverson
BACKGROUND: Compared with open surgery, minimally invasive surgery for colon cancer has been shown to improve short-term outcomes and yield equivalent long-term oncologic results. It remains to be seen if oncologic outcomes for the minimally invasive approach for rectal cancer are equivalent to traditional open rectal resection. METHODS: We conducted a systematic review of Medline, SCOPUS, and Cochrane databases. Relevant studies were selected using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines...
September 5, 2018: Annals of Surgical Oncology
Jenica N Upshaw
Patients with breast cancer have higher rates of cardiovascular disease than age-matched controls. Anthracyclines and trastuzumab increase the risk of heart failure (HF) and radiation increases the risk of ischemic heart disease, valvular disease and HF. Older age, low normal ejection fraction, history of coronary artery disease (CAD), cardiac risk factors, higher cumulative anthracycline exposure, combination anthracycline and trastuzumab and/or radiation all increase the risk of cardiac events post treatment...
August 2018: Gland Surgery
Evonne T Curran
This outbreak column uses the Health Protection Scotland (HPS) Outbreak Process and Algorithm to examine and reflect on a published outbreak report. The report involved an extensively drug-resistant Acinetobacter baumannii in an oncology unit. High-reliability theory is then used to reflect on how the outbreak was managed and consider how best to improve local outbreak prevention, preparedness, detection and management. The conclusion of this exercise is that if the possibility of an era of untreatable infections caused by antibiotic-resistant organisms is to be significantly postponed, Infection Prevention and Control Teams must improve their ability to get others to prevent cross-transmission in the absence of recognised risks...
September 2018: Journal of Infection Prevention
Juhi M Purswani, Nitin Ohri, Colin Champ
Purpose: Accurate evaluation of patients' health status is a key component of the workup, treatment, and follow-up of cancer patients. Assessments by clinicians (eg, performance status, toxicity grade) and patients (eg, quality of life) play a critical role in current practice but have significant limitations. Technological advances now provide an opportunity to track a new class of objective measures of patient activity, such as daily step counts. Here, we describe recent efforts to incorporate this technology into the field of oncology...
2018: Cancer Management and Research
Treya M Long, Shoshana R Rath, Karen E Wallman, Erin K Howie, Leon M Straker, Andrew Bullock, Thomas S Walwyn, Nicholas G Gottardo, Catherine H Cole, Catherine S Choong, Louise H Naylor
Adolescent and young adult (AYA) survivors of pediatric oncology related cerebral insult are vulnerable to numerous treatment-induced deficits that significantly enhance cardiovascular disease risk. Regular exercise improves endothelial function, fitness, body composition and musculoskeletal function which may reduce predisposition for cardiovascular disease. Here we assessed the feasibility and effectiveness of a 24-week exercise intervention on cardiovascular, physical and metabolic outcomes in this population...
2018: PloS One
Rachel Hirschey, Wei Pan, Marilyn Hockenberry, Gretchen Kimmick, Ryan Shaw, Isaac Lipkus
BACKGROUND: Exercise outcome expectations (OEs) (ie, what one expects to obtain or avoid by exercising) are influential to increase exercise among cancer survivors. OBJECTIVE: The aim of this study was to measure the accessibility (ie, frequency one thinks about exercise resulting in an outcome) and importance (ie, one's value of the outcome) of OEs among breast cancer survivors. METHODS: Stage IA to IIB breast cancer survivors who were 1 to 5 years posttreatment completed OE questionnaires...
August 7, 2018: Cancer Nursing
Fausto Roila, Guglielmo Fumi, Benedetta Ruggeri, Andrea Antonuzzo, Carla Ripamonti, Sonia Fatigoni, Luigi Cavanna, Stefania Gori, Alessandra Fabi, Nicola Marzano, Claudio Graiff, Vitaliana De Sanctis, Aurora Mirabile, Samantha Serpentini, Chiara Bocci, Maria Simona Pino, Giuseppina Cilenti, Claudio Verusio, Enzo Ballatori
BACKGROUND: Fatigue is one of the most distressing symptoms of cancer patients. Its characteristics and impact on quality of life have not been fully explored and treatment of cancer-related fatigue in Italian oncological centers has not been codified. METHODS: A cross-sectional study was carried out on all patients attending for any reason the 24 participating centers in two non-consecutive days. Patients with fatigue filled out the Brief Fatigue Inventory (BFI) questionnaire and reported any pharmacological or non-pharmacological treatment for fatigue...
August 6, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Philippe Timmermans, Filip Rega, Jan Bogaert, Marie-Christine Herregods
Neuroendocrine tumours are a rare malignancy, which can be complicated by a carcinoid syndrome and, in more rare cases, also valve destruction. The correct timing for surgical repair remains unknown. We report the first-in-men exercise cardiac magnetic resonance imaging with pulmonary artery catheter measurements in order to better understand the haemodynamic impact of isolated tricuspid valve insufficiency in a low symptomatic patient. Not pressure but volume overload is the key factor in the development of symptoms, as long as the right ventricular function is intact...
October 2018: ESC Heart Failure
Linda Trinh, Dominick A Strom, Jaime N Wong, Kerry S Courneya
OBJECTIVES: Few exercise oncology trials have compared aerobic with strength exercise or compared combined exercise (ie, aerobic and strength training) with aerobic only or strength only. It is unknown what single or combined exercise modality is optimal for quality of life (QoL) in cancer survivors. The purpose of this study is to estimate the prevalence of meeting the combined and independent aerobic and strength exercise guidelines in kidney cancer survivors (KCS) and determine any associations with QoL...
October 2018: Psycho-oncology
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