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https://www.readbyqxmd.com/read/27906096/biological-and-functional-evaluation-of-a-novel-pyrolytic-carbon-implant-for-the-treatment-of-focal-osteochondral-defects-in-the-medial-femoral-condyle-assessment-in-a-canine-model
#1
Samantha L Salkeld, Laura P Patron, Joan C Lien, Stephen D Cook, Deryk G Jones
BACKGROUND: Osteochondral defects continue to be a clinical treatment challenge, and when left untreated, may cause pain and functional impairment. Pyrolytic carbon is a unique isotropic biomaterial used in heart valve and small joint replacements due to its excellent wear properties and biocompatibility with bone and articular cartilage. Therefore, a proposed solution is to utilize a focal pyrolytic carbon hemiarthroplasty implant as an alternative resurfacing treatment strategy for isolated cartilage lesions...
December 1, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27905884/the-efficacy-of-pivmecillinam-3%C3%A2-days-or-5%C3%A2-days%C3%A2-t-i-d-against-community-acquired-uncomplicated-lower-urinary-tract-infections-a-randomized-double-blinded-placebo-controlled-clinical-trial-study-protocol
#2
Filip Jansåker, Niels Frimodt-Møller, Lars Bjerrum, Jenny Dahl Knudsen
BACKGROUND: Uncomplicated lower urinary tract infections (LUTI) are very common, and presumably around 200,000 female patients are treated for this annually in Denmark. The current Danish national clinical practice guidelines recommend pivmecillinam as a first-line drug (i.e., 400 mg t.i.d. for 3 days). Pivmecillinam is also one of the first-line drugs recommended in the international guidelines for LUTIs (i.e., 400 mg b.i.d. for 5 days). The international recommended duration is based on evidence saying that a 7-day regimen is better than a 3-day regimen...
December 1, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27905250/changes-to-nhs-england-s-stand-alone-policies
#3
(no author information available yet)
When NHS England was set up it published a series of generic policies to guide its decision making for directly commissioned services. These policies apply to all of NHS England's commissioning responsibilities, rather than being service-specific. However, stand-alone policies are required in four areas: » In-year service developments. » Individual funding requests. » Funding for experimental and unproven treatments. » Continuing funding after clinical trials. Developments in these areas are not commissioned routinely or subject to mandated guidance from the National Institute for Health and Care Excellence...
December 1, 2016: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/27905211/minimally-invasive-mitral-repair-surgery-why-does-controversy-still-persist
#4
Jeevan Nagendran, Jorge Catrip, Katie L Losenno, Corey Adams, Bob Kiaii, Michael W A Chu
Surgical treatment for mitral valve disease has evolved and remains a rapidly expanding field. Minimally invasive mitral valve repair (MI-MVR) is a well-known alternative to conventional sternotomy mitral valve repair (cMVR). However, controversy as to the efficacy of MI-MVR persists, hindering the adoption and potential benefits of this less invasive approach. Areas covered: In this review, we provide an updated summary evaluation of the latest evidence, including observational studies, clinical trials and meta-analyses, regarding MI-MVR in comparison to cMVR...
December 1, 2016: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/27904931/-arthroscopic-tenodesis-or-tenotomy-of-the-long-head-of-the-biceps-tendon-in-preselected-patients-does-it-make-a%C3%A2-difference
#5
M Kerschbaum, N Maziak, M Scheuermann, M Scheibel
BACKGROUND: Are there clinical, cosmetic and/or structural differences between tenotomy and tenodesis of the long head of the biceps tendon (LHB) in patients selected according to commonly used indication criteria? MATERIAL AND METHODS: A total of 85 patients were included in this study. An LHB tenodesis (LHB-TD) was performed in 49 patients and a tenotomy (LHB-TT) in 36 patients. In addition to a standardized examination, the age and gender adjusted Constant score (aCS), the LHB score and the subjective shoulder value (SSV) were assessed...
November 30, 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27904720/clinical-results-of-lateral-unicompartmental-knee-arthroplasty-minimum-2-year-follow-up
#6
Kyung Tae Kim, Song Lee, Jeehyoung Kim, Jin Woo Kim, Min Su Kang
BACKGROUND: We investigated the clinical results and early complications after lateral unicompartmental knee arthroplasty (UKA) using the Zimmer unicompartmental high-flex knee (ZUK) prosthesis with a minimum follow-up of 2 years. METHODS: Twenty-seven patients (30 cases) who underwent lateral UKA with the ZUK prosthesis between January 2011 and February 2014 were selected for this study. The mean age of the patients was 63.3 years at the time of surgery, and the mean followup was 3 years and 2 months (range, 24 to 48 months)...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27904716/is-anterior-bridge-plating-for-mid-shaft-humeral-fractures-a-suitable-option-for-patients-predominantly-involved-in-overhead-activities-a-functional-outcome-study-in-athletes-and-manual-laborers
#7
Abhishek S Mahajan, Young Gun Kim, Jae Hwa Kim, Prashanth D'sa, Azhar Lakhani, Hyun Soo Ok
BACKGROUND: To assess the functional and radiological outcomes of minimally invasive anterior bridge plating (ABP) for mid-shaft humerus fractures in patients predominantly involved in overhead activities (athletes and manual laborers). METHODS: Forty-eight patients fulfilling inclusion criteria were treated with ABP at a level-I trauma center using a 4.5-mm dynamic/locking compression plate and followed for a period of 1 year. Functional outcome was assessed using the Constant, Mayo elbow, and Disabilities of the Arm, Shoulder and Hand (DASH) scores...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27904246/noninvasive-imaging-of-the-biliary-system-relevant-to-percutaneous-interventions
#8
REVIEW
Stephen Thomas, Kayleen Jahangir
Clinical data such as history, physical examination, and laboratory tests are useful in identifying patients with biliary obstruction and biliary sources of infection. However, if intervention is planned, noninvasive imaging is needed to confirm the presence, location, and extent of the disease process. Currently, the most commonly available and used noninvasive modalities are ultrasound (US), computed tomography (CT), magnetic resonance (MR), and nuclear medicine hepatobiliary scintigraphy (HIDA). US is quick, portable, readily available, and is commonly the first imaging modality used when biliary pathology is suspected...
December 2016: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/27904221/what-have-we-learned-from-100-success-of-press-fit-condylar-rotating-platform-posterior-stabilized-knees-a-5-10-years-followup-by-a-nondesigner
#9
Shrinand V Vaidya, Siddharth Virani, Rajendra Phunde, Abhishek Mahajan
BACKGROUND: Total joint arthroplasties of the hip and knee represent a remarkable feat of modern medicine in terms of reducing pain and restoring function to millions of patients afflicted with severe arthritis. Oftentimes, the performance and longevity of new implants and devices are based on limited data. This is the first study by a non-designer on the press fit condylar rotating platform posterior stabilized (PFC-RP-PS) design with 100' success. This has a relevance, vis-á -vis bias that one may have in terms of reproducibility of technique and funding from the manufacturer...
November 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27904213/functional-outcome-of-intraarticular-distal-humerus-fracture-fixation-using-triceps-sparing-paratricipital-approach
#10
Vishal Yadav, Pulak Sharma, Ashish Gohiya
BACKGROUND: Displaced intraarticular distal humerus fracture has been conventionally treated operatively with various triceps disrupting approaches. These approaches are associated with several complications, such as triceps weakness, nonunion or delayed union of osteotomy, implant prominence, and delayed mobilization of the elbow. We present the functional outcome of intraarticular distal humerus fracture fixation using a triceps-sparing paratricipital approach which allows early elbow mobilization and preserving triceps strength...
November 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27904211/post-operative-pain-management-in-shoulder-surgery-suprascapular-and-axillary-nerve-block-by-arthroscope-assisted-catheter-placement
#11
H Çağdaş Basat, D Hakan Uçar, Mehmet Armangil, Berk Güçlü, Mehmet Demirtaş
BACKGROUND: Postoperative pain management is the part of shoulder surgery to improve patient satisfaction, start rehabilitation process rapidly and decrease for hospital stay. Various treatment modalities have been used for pain management, but they have some limitations, side effects and risks. Throughout intraoperative and postoperative period, nerve blocks have been used more popularly than others because of efficacy. For the regional nerve block, local anesthetic should be infiltrated close to the nerve for maximum effect...
November 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27903114/a-quantitative-analysis-of-craniopharyngioma-cyst-expansion-during-and-after-radiation-therapy-and-surgical-implications
#12
Kelly Lamiman, Kenneth K Wong, Benita Tamrazi, Jason D Nosrati, Arthur Olch, Eric L Chang, Erin N Kiehna
OBJECTIVE When complete resection of craniopharyngioma is not achievable or the sequelae are prohibitive, limited surgery and radiation therapy have demonstrated excellent local disease control while minimizing treatment-related sequelae. When residual tissue exists, there is a propensity for further cyst development and expansion during and after radiation therapy. This can result in obstructive hydrocephalus, visual changes, and/or clinical decline. The authors present a quantitative analysis of cyst expansion during and after radiotherapy and examine how it affected subsequent management...
December 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27903081/percutaneous-microwave-ablation-of-renal-cell-carcinoma-is-safe-in-patients-with-renal-dysfunction
#13
Yan Lin, Ping Liang, Xiao-Ling Yu, Jie Yu, Zhi-Gang Cheng, Zhi-Yu Han, Fangyi Liu
OBJECTIVES: To present the clinical effect of microwave ablation(MWA) on renal cell carcinoma(RCC) of the patients with renal dysfunction, mainly focusing on the extent of renal tumor control and damage to the residual kidney function. METHODS AND MATERIALS: From 2006 to 2014, 19 tumors of 18 patients with renal dysfunction underwent percutaneous ultrasound-guided MWA in our institution. The tumor diameters range from 1.9 to 5.0cm. The serum creatinine and urea levels of each patient pre-MWA, 1 day after MWA and the most recent occasion on record at our institution were collected...
November 30, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27902676/dural-sinus-cerebral-venous-thrombosis-in-a-pediatric-trauma-patient-a-rare-complication-after-closed-head-injury
#14
Jonathan Wilcher, Michelle Pannell
OBJECTIVE: Closed head injury rarely predisposes patients, particularly children, to the development of dural sinus thrombosis. In addition, most cases of sinus thrombosis are subacute in nature. The following is a case report of a precipitous course of dural sinus thrombosis after closed head injury in a pediatric trauma patient. DESCRIPTION: A 14-year-old African American girl presented to the emergency department as a trauma activation. She was an unrestrained rear-seat passenger involved in a motor vehicle collision during which she was ejected...
December 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27902615/the-prognostic-significance-of-the-birmingham-vasculitis-activity-score-bvas-with-systemic-vasculitis-patients-transferred-to-the-intensive-care-unit-icu
#15
Federico Biscetti, Angela Carbonella, Federico Parisi, Silvia Laura Bosello, Franco Schiavon, Roberto Padoan, Elisa Gremese, Gianfranco Ferraccioli
Systemic vasculitides represent a heterogeneous group of diseases that share clinical features including respiratory distress, renal dysfunction, and neurologic disorders. These diseases may often cause life-threatening complications requiring admission to an intensive care unit (ICU). The aim of the study was to evaluate the validity and responsiveness of Birmingham Vasculitis Activity Score (BVAS) score to predict survival in patients with systemic vasculitides admitted to ICU.A retrospective study was carried out from 2004 to 2014 in 18 patients with systemic vasculitis admitted to 2 different Rheumatology divisions and transferred to ICU due to clinical worsening, with a length of stay beyond 24 hours...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27901333/fractional-flow-reserve-lessons-from-platform-and-future-perspectives
#16
Gianluca Pontone, Patrizia Carità, Massimo Verdecchia, Dario Buccheri, Daniele Andreini, Andrea I Guaricci, Mark Rabbat, Mauro Pepi
In the treatment of stable coronary artery disease (CAD) the identification of patients who may gain the highest benefit from further invasive treatments is of pivotal importance for the healthcare system. In this setting, it has been established that an ischemia-guided revascularization strategy yields improved clinical outcomes in a cost- effective fashion compared with anatomy-guided revascularization alone. Invasive fractional flow reserve (FFR) is considered the gold standard, especially in the intermediate-range atherosclerotic lesions, for assessing lesion specific ischemia at the time of invasive coronary angiography and has now become the standard of reference for studies assessing the diagnostic performance of the various non-invasive stress tests...
November 30, 2016: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/27900978/penile-calcific-uremic-arteriolopathy-occurring-postparathyroidectomy-in-a-hemodialysis-patient
#17
Salah Omar Bashir, Mahmoud A Aamer, Hayder A Omer, Mohamed D Morsy
Calcific uremic arteriolopathy (CUA), also known as calciphylaxis, is a rare condition most frequently seen in patients with advanced chronic kidney disease. The clinical picture is characterized by painful skin lesions and ulcerations. The underlying pathology is medial calcification and intimal proliferation with microthrombi of small arteries. CUA is commonly associated with secondary hyperparathyroidism and high serum calcium and phosphate products. This article reports an atypical case where CUA developed after parathyroidectomy and in the course of treatment of hungry bone syndrome...
November 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27900703/the-treatment-of-distal-third-humeral-diaphyseal-fractures-is-there-still-a-place-for-the-external-fixation
#18
N Tartaglia, G Vicenti, M Carrozzo, A Abate, F Rifino, G Picca, G Solarino, B Moretti
INTRODUCTION: The treatment for humeral diaphyseal fractures is still controversial. The purpose of this study was to evaluate the clinical and radiographic outcomes of treating humeral distal third diaphyseal fractures by using external fixation technique. MATERIALS AND METHODS: We retrospectively review 65 cases of diaphyseal humeral fractures (31 type A, 23 type B and 11 type C of the AO/OTA classification) treated with external fixation (Orthofix FAD small) between 2008 and 2013...
December 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27900604/assessment-of-interstitial-lung-disease-in-sj%C3%A3-gren-s-syndrome-by-lung-ultrasound-a-pilot-study-of-correlation-with-high-resolution-chest-tomography
#19
Pablo Guisado Vasco, Gonzalo de Luna Cardenal, Isabel Martín Garrido, José Manuel Luque Pinilla, Guadalupe Fraile Rodríguez, Juan José Nava Mateo, Daniel Carnevalli Ruiz
The background of this study is to assess the accuracy of lung ultrasound (LUS) to diagnose interstitial lung disease (ILD) in Sjögren's syndrome (Sjs), in patients who have any alterations in pulmonary function tests (PFT) or respiratory symptoms. LUS was correlated with chest tomography (hrCT), considering it as the imaging gold standard technique to diagnose ILD. This is a pilot, multicenter, cross-sectional, and consecutive-case study. The inclusion criteria are ≥18 years old, Signs and symptoms: according to ACEG 2002 criteria, respiratory symptoms (dyspnea, cough), or any alterations in PFR...
November 29, 2016: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/27900546/validation-of-the-chinese-version-of-functional-assessment-of-anorexia-cachexia-therapy-faact-scale-for-measuring-quality-of-life-in-cancer-patients-with-cachexia
#20
Ting Zhou, Kaixiang Yang, Sudip Thapa, Qiang Fu, Yongsheng Jiang, Shiying Yu
PURPOSE: The assessment of quality of life (QOL) is an important part of cachexia management for cancer patients. Functional assessment of anorexia-cachexia therapy (FAACT), a specific QOL instrument for cachexia patients, has not been validated in Chinese population. The aim of this study was to validate the FAACT scale in Chinese cancer patients for its future use. METHODS: Eligible cancer patients were included in our study. Patients' demographic and clinical characteristics were collected from the electronic medical records...
November 29, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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