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https://www.readbyqxmd.com/read/30502782/prediction-of-drug-related-risks-using-clinical-context-information-in-longitudinal-claims-data
#1
Andreas D Meid, Andreas Groll, Dirk Heider, Sarah Mächler, Jürgen-Bernhard Adler, Christian Günster, Hans-Helmut König, Walter E Haefeli
OBJECTIVES: To develop and internally validate prediction models for medication-related risks arising from overuse, misuse, and underuse that utilize clinical context information and are suitable for routine risk assessment in claims data (i.e., medication-based models predicting the risk for hospital admission apparent in routine claims data or MEDI-RADAR). METHODS: Based on nationwide claims from health-insured persons in Germany between 2010 and 2012, we drew a random sample of people aged ≥65 years (N = 22,500 randomly allocated to training set, N = 7500 to validation set)...
December 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30216018/geriatric-assessment-an-office-based-approach
#2
Paul E Tatum Iii, Shaida Talebreza, Jeanette S Ross
Family physicians should be proficient in geriatric assessment because, as society ages, older adults will constitute an increasing proportion of patients. Geriatric assessment evaluates medical, social, and environmental factors that influence overall well-being, and addresses functional status, fall risk, medication review, nutrition, vision, hearing, cognition, mood, and toileting. The Medicare Annual Wellness Visit includes the key elements of geriatric assessment performed by family physicians. Comprehensive geriatric assessment can lead to early recognition of problems that impair quality of life by identifying areas for focused intervention, but a rolling geriatric assessment over several visits can also effectively identify subtle or hidden problems...
June 15, 2018: American Family Physician
https://www.readbyqxmd.com/read/29567842/prevalence-of-potentially-inappropriate-prescribing-in-a-subpopulation-of-older-european-clinical-trial-participants-a-cross-sectional-study
#3
MULTICENTER STUDY
David O Riordan, Carole Elodie Aubert, Kieran A Walsh, Anette Van Dorland, Nicolas Rodondi, Robert S Du Puy, Rosalinde K E Poortvliet, Jacobijn Gussekloo, Carol Sinnott, Stephen Byrne, Rose Galvin, J Wouter Jukema, Simon P Mooijaart, Christine Baumgartner, Vera McCarthy, Elaine K Walsh, Tinh-Hai Collet, Olaf M Dekkers, Manuel R Blum, Patricia M Kearney
OBJECTIVES: To estimate and compare the prevalence and type of potentially inappropriate prescribing (PIP) and potential prescribing omissions (PPOs) among community-dwelling older adults (≥65 years) enrolled to a clinical trial in three European countries. DESIGN: A secondary analysis of the Thyroid Hormone Replacement for Subclinical Hypothyroidism Trial dataset. PARTICIPANTS: A subset of 48/80 PIP and 22/34 PPOs indicators from the Screening Tool of Older Persons Prescriptions/Screening Tool to Alert doctors to Right Treatment (STOPP/START) V2 criteria were applied to prescribed medication data for 532/737 trial participants in Ireland, Switzerland and the Netherlands...
March 22, 2018: BMJ Open
https://www.readbyqxmd.com/read/29162290/reduction-of-pharmaceutical-expenditure-by-a-drug-appropriateness-intervention-in-polymedicated-elderly-subjects-in-catalonia-spain
#4
Lluís Campins, Mateu Serra-Prat, Elisabet Palomera, Ignasi Bolibar, Miquel Àngel Martínez, Pedro Gallo
OBJECTIVE: To assess the monetary savings resulting from a pharmacist intervention on the appropriateness of prescribed drugs in community-dwelling polymedicated (≥8 drugs) elderly people (≥70 years). METHOD: An evaluation of pharmaceutical expenditure reduction was performed within a randomised, multicentre clinical trial. The study intervention consisted of a pharmacist evaluation of all drugs prescribed to each patient using the "Good Palliative-Geriatric Practice" algorithm and the "Screening Tool of Older Persons Prescriptions/Screening Tool to Alert doctors to Right Treatment" criteria (STOPP/START)...
November 18, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28971492/drug-related-problems-identified-during-medication-review-before-and-after-the-introduction-of-a-clinical-decision-support-system
#5
S Verdoorn, H F Kwint, P Hoogland, J Gussekloo, M L Bouvy
WHAT IS KNOWN AND OBJECTIVE: To facilitate the identification of drug-related problems (DRPs) during medication review, several tools have been developed. Explicit criteria, like Beers criteria or STOPP (Screening Tool of Older Peoples' Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment) criteria, can easily be integrated into a clinical decision support system (CDSS). The aim of this study was to investigate the effect of adding a CDSS to medication review software on identifying and solving DRPs in daily pharmacy practice...
April 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28920183/number-of-medications-or-number-of-diseases-what-influences-underprescribing
#6
Eva Cedilnik Gorup, Marija Petek Šter
PURPOSE: An increasing number of older adults suffer from multimorbidity and receive multiple medications. Despite that, underprescribing of potentially beneficial medications is widespread in this population. Our aim was to examine influence of polypharmacy and multimorbidity on the presence of prescribing omissions (PO) in general practice attenders. METHODS: We conducted a cross-sectional study of older adults attending general practices in Slovenia who were regularly prescribed at least one medication...
December 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28432600/potentially-inappropriate-antihypertensive-prescriptions-to-elderly-patients-results-of-a-prospective-observational-study
#7
MULTICENTER STUDY
Paola H Ponte Márquez, Olga H Torres, Anonio San-José, Xavier Vidal, Antonia Agustí, Francesc Formiga, Alfonso López-Soto, Nieves Ramírez-Duque, Antonio Fernández-Moyano, Juana Garcia-Moreno, Juan A Arroyo, Domingo Ruiz
INTRODUCTION: Previous studies of antihypertensive treatment of older patients have focused on blood pressure control, cardiovascular risk or adherence, whereas data on inappropriate antihypertensive prescriptions to older patients are scarce. OBJECTIVES: The aim of the study was to assess inappropriate antihypertensive prescriptions to older patients. METHODS: An observational, prospective multicentric study was conducted to assess potentially inappropriate prescription of antihypertensive drugs, in patients aged 75 years and older with arterial hypertension (HTN), in the month prior to hospital admission, using four instruments: Beers, Screening Tool of Older Person's Prescriptions (STOPP), Screening Tool to Alert Doctors to the Right Treatment (START) and Assessing Care of Vulnerable Elders 3 (ACOVE-3)...
June 2017: Drugs & Aging
https://www.readbyqxmd.com/read/28422415/impact-of-hospitalization-in-an-acute-geriatric-unit-on-polypharmacy-and-potentially-inappropriate-prescriptions-a-retrospective-study
#8
Marta Gutiérrez-Valencia, Mikel Izquierdo, Vincenzo Malafarina, Javier Alonso-Renedo, Belén González-Glaría, Beatriz Larrayoz-Sola, María Pilar Monforte-Gasque, Pello Latasa-Zamalloa, Nicolás Martínez-Velilla
AIM: Polypharmacy is a highly prevalent geriatric syndrome, and hospitalizations can worsen it. The aim of the present study was to analyze the influence of hospitalization on polypharmacy and indicators of quality of prescribing, and their possible association with health outcomes. METHODS: A retrospective study of 200 patients discharged from an acute geriatric unit was carried out. Indicators of quality of prescription were registered at admission and discharge: polypharmacy defined as ≥5 medications, hyperpolypharmacy (≥10), potentially inappropriate prescribing by Beers and Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) criteria, potentially prescribing omissions by Screening Tool to Alert doctors to the Right Treatment (START) criteria, drug interactions and anticholinergic burden measured with the Anticholinergic Risk Scale...
December 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28188508/potentially-inappropriate-prescribing-and-associated-factors-in-elderly-patients-at-hospital-discharge-in-brazil-a-cross-sectional-study
#9
Ana Luiza Pereira Moreira Mori, Renata Cunha Carvalho, Patricia Melo Aguiar, Maria Goretti Farias de Lima, Magali da Silva Pacheco Nobre Rossi, José Fernando Salvador Carrillo, Egídio Lima Dórea, Sílvia Storpirtis
Background The Screening Tool of Older Persons' Prescriptions/Screening Tool to Alert doctors to Right Treatment (STOPP/START) criteria is used to identify instances of potentially inappropriate prescribing in a patient's medication regimen. Objective To determine the prevalence and predictors of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) among elderly patients at hospital discharge. Setting A university hospital medical clinic in Brazil. Method Discharge prescriptions were examined using the STOPP/START criteria...
April 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28064167/potentially-inappropriate-prescribing-to-older-patients-in-primary-care-in-the-netherlands-a-retrospective-longitudinal-study
#10
Linette Bruin-Huisman, Ameen Abu-Hanna, Henk C P M van Weert, Erna Beers
Background: potentially inappropriate prescribing (PIP) is associated with adverse health effects in older patients. PIP comprises prescription of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs). Objective: to estimate the prevalence of PIMs and PPOs among older patients in primary care. Design: retrospective longitudinal study. Setting: routinely collected data of 182,000 patients of 49 general practitioners (GPs) gathered in the GPs' database of the Academic Medical Center of Amsterdam, the Netherlands...
July 1, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28008599/screening-tool-of-older-person-s-prescriptions-screening-tools-to-alert-doctors-to-right-treatment-medication-criteria-modified-for-u-s-nursing-home-setting
#11
Dmitry Khodyakov, Aileen Ochoa, Brianne L Olivieri-Mui, Carla Bouwmeester, Barbara J Zarowitz, Meenakshi Patel, Diana Ching, Becky Briesacher
OBJECTIVES: To develop a set of prescribing indicators measurable with available data from electronic nursing home (NH) databases by adapting the European-based 2014 Screening Tool of Older Person's Prescriptions (STOPP) and Screening Tools to Alert Doctors to Right Treatment (START) criteria of potentially inappropriate and underused medications for the U.S. SETTING: <AbstractText Label="DESIGN" NlmCategory="METHODS">A two-stage expert panel process. In the first stage, the investigator team reviewed 114 criteria for compatibility and measurability...
March 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27959845/-inappropriate-prescription-in-elderly-inpatients
#12
Ana V Fajreldines, Jorge T Insua, Eduardo Schnitzler
One of the causes of preventable adverse drug events (EAM) in the older adult population is the inappropriate prescription (PIM), i.e. that prescription where risks outweigh clinical benefits. The aim of this study is to determine the incidence of PIM with Beers criteria and Screening Tool of older person's prescriptions (STOPP), Potentially Prescribing Omissions (PPO) with Screening Tool to alert doctors to Right Treatments (START), and the average costs of hospitalization. This is an incidence study on a sample of patients over 64 years hospitalized, from January to July 2014 at a university hospital...
2016: Medicina
https://www.readbyqxmd.com/read/27943247/long-term-outcomes-of-medication-intervention-using-the-screening-tool-of-older-persons-potentially-inappropriate-prescriptions-screening-tool-to-alert-doctors-to-right-treatment-criteria
#13
Dvora Frankenthal, Avi Israeli, Yoseph Caraco, Yaffa Lerman, Edward Kalendaryev, Gisele Zandman-Goddard, Yehuda Lerman
OBJECTIVES: To compare 24-month outcomes of participants of a prospective randomized controlled trial (RCT) assigned to undergo a medication intervention of orally communicated recommendations based on Screening Tool of Older Persons potentially inappropriate Prescriptions (STOPP) and Screening Tool to Alert Doctors to Right Treatment (START) (intervention group) with outcomes of those assigned to undergo written medication review (control group). DESIGN: Retrospective cohort study...
February 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27625743/impact-of-pharmacist-provided-medication-therapy-management-on-healthcare-quality-and-utilization-in-recently-discharged-elderly-patients
#14
Jordan D Haag, Amanda Z Davis, Robert W Hoel, Jeffrey J Armon, Laura J Odell, Ross A Dierkhising, Paul Y Takahashi
BACKGROUND: The optimization of medication use during care transitions represents an opportunity to improve overall health-related outcomes. The utilization of clinical pharmacists during care transitions has demonstrated benefit, although the optimal method of integration during the care transition process remains unclear. OBJECTIVE: To evaluate the impact of pharmacist-provided telephonic medication therapy management (MTM) on care quality in a care transitions program (CTP) for high-risk older adults...
July 2016: American Health & Drug Benefits
https://www.readbyqxmd.com/read/27382265/inappropriate-prescribing-of-antithrombotic-therapy-in-ethiopian-elderly-population-using-updated-2015-stopp-start-criteria-a-cross-sectional-study
#15
Henok Getachew, Akshaya Srikanth Bhagavathula, Tamrat Befekadu Abebe, Sewunet Admasu Belachew
BACKGROUND: Inappropriate use of antiplatelets and anticoagulants among elderly patients increases the risk of adverse outcomes. The aim of this study was to assess the prevalence of inappropriate prescribing of antithrombotic therapy in hospitalized elderly patients. METHODS: A retrospective cross-sectional, single-center study was conducted at the Gondar University Hospital. A total of 156 hospitalized elderly patients fulfilling the inclusion/exclusion criteria were included in the study...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27343120/potentially-inappropriate-medications-in-a-sample-of-portuguese-nursing-home-residents-does-the-choice-of-screening-tools-matter
#16
MULTICENTER STUDY
Filipa Alves da Costa, Catarina Periquito, Maria Clara Carneiro, Pedro Oliveira, Ana Isabel Fernandes, Patrícia Cavaco-Silva
UNLABELLED: Background Potentially inappropriate medications (PIMs) are often found in high proportion among the elderly population. The STOPP criteria have been suggested to detect more PIMs in European elderly than the Beers criteria. Objective This study aimed to determine the prevalence of PIMs and potential prescribing omissions (PPOs) in a sample of Portuguese nursing homes residents. Setting Four elderly facilities in mainland Portugal Method A descriptive cross-sectional study was used...
October 2016: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/27265382/-medication-reconciliation-in-patients-over-75-years
#17
B Rubio-Cebrián, I Santaolalla-García, I Martín-Casasempere, M Segura-Bedmar
OBJECTIVE: To continue with the implementation of the medication reconciliation process on admission, and to analyse potentially inappropriate prescriptions according to the STOPP-START -Screening Tool of Older Person's potentially inappropriate Prescriptions/Screening Tool to Alert doctors to the Right (indicated) Treatment- criteria, and drug interactions. To extend the process of reconciliation at hospital discharge from the Cardiology and Chest Diseases departments. MATERIAL AND METHODS: Retrospective observational study that included patients over 75 years old...
June 2016: Revista de Calidad Asistencial: Organo de la Sociedad Española de Calidad Asistencial
https://www.readbyqxmd.com/read/27136457/potentially-inappropriate-prescribing-according-to-stopp-and-start-and-adverse-outcomes-in-community-dwelling-older-people-a-prospective-cohort-study
#18
Frank Moriarty, Kathleen Bennett, Caitriona Cahir, Rose Anne Kenny, Tom Fahey
AIMS: This study aims to determine if potentially inappropriate prescribing (PIP) is associated with increased healthcare utilization, functional decline and reduced quality of life (QoL) in a community-dwelling older cohort. METHOD: This prospective cohort study included participants aged ≥65 years from The Irish Longitudinal Study on Ageing (TILDA) with linked administrative pharmacy claims data who were followed up after 2 years. PIP was defined by the Screening Tool for Older Persons Prescriptions (STOPP) and Screening Tool to Alert doctors to Right Treatment (START)...
September 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27065309/medication-review-using-a-systematic-tool-to-reduce-inappropriate-prescribing-strip-in-adults-with-an-intellectual-disability-a-pilot-study
#19
Rianne J Zaal, Susan Ebbers, Mirka Borms, Bart de Koning, Erna Mombarg, Piet Ooms, Hans Vollaard, Patricia M L A van den Bemt, Heleen M Evenhuis
A Systematic Tool to Reduce Inappropriate Prescribing (STRIP), which includes the Screening Tool to Alert doctors to Right Treatment (START) and the Screening Tool of Older Peoples' Prescriptions (STOPP), has recently been developed in the Netherlands for older patients with polypharmacy in the general population. Active involvement of the patient is part of this systematic multidisciplinary medication review. Although annual review of pharmacotherapy is recommended for people with an intellectual disability (ID), a specific tool for this population is not yet available...
August 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/26990017/effectiveness-of-the-stopp-start-screening-tool-of-older-persons-potentially-inappropriate-prescriptions-screening-tool-to-alert-doctors-to-the-right-treatment-criteria-systematic-review-and-meta-analysis-of-randomized-controlled-studies
#20
REVIEW
B Hill-Taylor, K A Walsh, S Stewart, J Hayden, S Byrne, I S Sketris
WHAT IS KNOWN AND OBJECTIVE: STOPP/START are explicit screening tools that identify potentially inappropriate prescribing in older adults. Our objective was to update our 2013 systematic review that showed limited evidence of impact, using new evidence from randomized controlled trials (RCTs) assessing clinical, humanistic and economic outcomes in older adults. METHODS: We performed a search of PubMed, EMBASE, CINAHL, Web of Science and grey literature for RCTs published in English since the previous review through June 2014...
April 2016: Journal of Clinical Pharmacy and Therapeutics
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