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Cancer AND oncology

Jessica Krebs, Sonja Wasner, Sainab Egloffstein, Michael P Lux, Eva Morawa, Matthias W Beckmann, Yesim Erim
PURPOSE: The objective of the study was to find out about psychological distress, fear of progression, and resilience levels in patients with breast cancer and gynecological tumors asking for a second opinion concerning their oncological treatment. METHODS: 158 female cancer patients were assessed for those parameters in a questionnaire survey comprising SOC-13, FoP-Q-SF, and the NCCN distress thermometer. RESULTS: 16.2% of the breast cancer patients and 20...
October 16, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
Daniel Lam Cham Kee, Jocelyn Gal, Alexander T Falk, Renaud Schiappa, Marie-Eve Chand, Mathieu Gautier, Jérôme Doyen, Jean-Michel Hannoun-Levi
BACKGROUND: Brachytherapy boost after external beam radiotherapy for intermediate and high-risk prostate cancer is presented as an attractive technique in numerous retrospective and prospective studies. Currently, three randomized controlled trials comparing brachytherapy versus external beam radiotherapy boost used non-homogenous irradiation features. Therefore, we analyzed the oncological outcomes by a systematic review with meta-analysis of the randomized controlled trials. METHODS: We performed a systematic literature review of MEDLINE and COCHRANE databases up to 30/04/10 and we considered all published randomized controlled trials comparing brachytherapy versus external beam radiotherapy boost for intermediate and high-risk prostate cancer according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement...
October 11, 2018: Cancer Treatment Reviews
Lauren C Hand, Teresa H Thomas, Sarah Belcher, Grace Campbell, Young Ji Lee, Mary Roberge, Christina Lizaso, Dorinda Sparacio, Heidi S Donovan
OBJECTIVES: As gynecologic cancer care shifts to the outpatient setting, caregivers are instrumental in helping patients navigate the demands of the disease and treatment. Through social media, we aimed to understand the needs of caregivers of patients with gynecologic cancers and support services necessary to meet these needs. METHODS: On January 10, 2018, a monthly Twitter discussion session was hosted by the GYNecologic Cancer Social Media community (handle @GYNCSM) using the hashtag #GYNCSM...
October 15, 2018: International Journal of Gynecological Cancer
Ciro Andolfi, Konstantin Umanskiy
BACKGROUND: Robotic technology aims to obviate some of the limitations of conventional laparoscopic surgery, yet the role of robotics in colorectal surgery is still largely undefined and varies with respect to its application in abdominal versus pelvic surgery. METHODS: With this review, we aimed to highlight current developments in colorectal robotic surgery. We systematically searched the following databases: PubMed, EMBASE, and Cochrane Library. We critically reviewed the available literature on the use of robotic technology in colon and rectal surgery...
October 16, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Jennifer L Olson, Richard J Bold
Pancreatic adenocarcinoma is the 9th most common cancer in the United States and the 4th most common cause of cancer-related death given its poor prognosis. Areas covered: The authors have performed a literature search for pertinent published clinical trials, ongoing Phase 3 clinical trials, and current treatment guidelines using PubMed,, and NCCN, ASCO, ESMO, and JPS websites. The review itself discusses landmark studies and ongoing research into the chemotherapy regimens recommended by each oncologic society...
October 16, 2018: Expert Opinion on Pharmacotherapy
M Lövgren, N Mogensen, A Harila-Saari, P M Lähteenmäki, U Kreicbergs
Evidence favours sibling support as a standard of care in paediatric oncology (1). Guidelines published in 1999 by the International Society of Paediatric Oncology (2) recommended involving siblings in the ill child's care and supporting siblings during and after the illness. Studies have shown that this is something that siblings want and need (3) and lack of support has increased the risk of long-term psychological distress (4). Sibling support varies between countries. This article is protected by copyright...
October 16, 2018: Acta Paediatrica
Rebecca Ahlin, Fei Sjöberg, Cecilia Bull, Gunnar Steineck, Maria Hedelin
Preclinical studies indicate that an optimal diet during pelvic radiotherapy may be able to prevent radiation-induced survivorship diseases that diminish cancer survivors' intestinal health. We do not yet know what this optimal diet might be because scientific studies needed to determine what dietary advice might best be given to patients during treatment. Oncology clinics in Sweden were contacted to determine the nature of dietary advice given to gynaecological and prostate cancer patients at each clinic before, during and after radiotherapy...
October 9, 2018: Läkartidningen
Lucio N Gordan, Debra Patt
The outpatient community oncology setting is consistently less costly for cancer treatment as opposed to the outpatient hospital setting.
October 2018: American Journal of Managed Care
Ahmad Rajeh Saifan, Ahmad M Al Zoubi, Intima Alrimawi, Omar Melhem
AIM: This study aims to explore the psychological status of nurses working with cancer patients in Jordan. BACKGROUND: Literature shows that nurses face many stressors in their job, in particular oncology nurses. Some of them have psychiatric illness such as anxiety and depression. Most of the reviewed studies were conducted in developed countries, and none in the Middle East. METHOD: A qualitative descriptive approach was adopted, whereby interviews were conducted with 24 nurses that were selected from the oncology departments of one governmental hospital...
October 15, 2018: Journal of Nursing Management
Heng-Chuan Su, Yao Zhu, Si-Long Hu, Chang Liu, Guo-Wen Lin, Bo Dai, Ying-Jian Zhang, Ding-Wei Ye
BACKGROUND: This study evaluated the effect of technetium-99m (99m Tc)-labeled prostate-specific membrane antigen (PSMA)-based image-guided surgery on the oncologic outcomes for patients with primary or recurrent prostate cancer (PCa). METHODS: This study retrospectively analyzed 54 consecutive patients with PCa who underwent 99m Tc-labeled PSMA-based image-guided surgery between January 2016 and September 2017. These patients received a radical prostatectomy (RP) with pelvic lymph node dissection (PLND) or salvage lymph node dissection (sLND)...
October 15, 2018: Annals of Surgical Oncology
Robyn Loves, Deborah Tomlinson, Christina Baggott, David Dix, Paul Gibson, Shannon Hyslop, Donna L Johnston, Andrea D Orsey, Carol Portwine, Victoria Price, Tal Schechter, Magimairajan Vanan, Susan Kuczynski, Brenda Spiegler, George A Tomlinson, L Lee Dupuis, Lillian Sung
BACKGROUND: Objectives were to describe bothersome self-reported changes in taste in pediatric oncology and hematopoietic stem cell (HSCT) patients and to identify patient and treatment-related factors associated with bothersome taste changes. METHODS: We prospectively enrolled children and adolescents with cancer or pediatric HSCT recipients 8-18 years of age from three groups: inpatients receiving cancer treatments; outpatients in maintenance therapy for acute lymphoblastic leukemia (ALL); and outpatients in survivorship...
October 15, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Victor Hugo Fonseca de Jesus, Aldo Lourenço Abbade Dettino
At the 2018 Gastrointestinal Cancer Symposium, sponsored by the American Society of Clinical Oncology, significant advances in the management of hepatocellular carcinoma (HCC) were announced. In intermediate-stage disease (Barcelona Clinic Liver Cancer stage B), interest in combining transarterial chemoembolization and sorafenib has been reignited as a consequence of the TACTICS trial. In advanced-stage disease (BCLC C), external-beam radiotherapy combined with transarterial chemoembolization proved to be superior to sorafenib in patients with portal vein thrombosis according to the START trial...
2018: Journal of Hepatocellular Carcinoma
Joseph A Bovi
The incidence of brain metastases is projected to rise because survival rates of lung cancer, breast cancer, and melanoma continue to improve (1). The brain is being identified as a sanctuary site for harboring metastases despite excellent control of extracranial disease. This is thought to occur because the drug therapies that control extracranial disease have limited central nervous system (CNS) penetration. The development of brain metastases is a devastating diagnosis affecting both quality of life (QOL) and survival...
2018: Frontiers in Neurology
Toshinobu Hayashi, Mototsugu Shimokawa, Koichi Matsuo, Takanori Miyoshi, Yoko Toriyama, Chiaki Yokota, Jun Taniguchi, Kiyonori Hanada, Kyouichi Tsumagari, Noriko Okubo, Yoshimichi Koutake, Kohei Sakata, Yosei Kawamata, Takashi Goto, Yasufumi Tsurusaki, Makiko Koyabu
Purpose: Improvement in the control of delayed chemotherapy-induced nausea and vomiting (CINV) is needed. There is limited information on antiemetic prophylaxis for patients undergoing low-emetic-risk chemotherapy (LEC), and the optimal antiemetic treatment is not well understood. Therefore, we analyzed the risk factors for delayed CINV to aid in the development of individualized treatments. Patients and methods: This prospective multicenter study was conducted in 13 hospitals and included patients with solid cancers undergoing LEC...
2018: Cancer Management and Research
Anwar E Ahmed, Alhanouf N Albalawi, Eiman T Qureshey, Aisha T Qureshey, Nagarajkumar Yenugadhati, Hamdan Al-Jahdali, Abdul Rahman Jazieh
Background: Although psychological symptoms and oral health status are associated with health management and outcomes among cancer patients, their association has not been assessed in Saudi Arabia. We aimed to assess the symptoms of depression, anxiety, and stress and their association with their oral health status, adjusting for sociodemographic and clinical factors. Methods: A self-reported study included 375 adult cancer patients who received outpatient healthcare services in the Oncology Department, King Abdulaziz Medical City-Riyadh, Saudi Arabia, between April 1 and August 31, 2017...
2018: Breast Cancer: Targets and Therapy
Xiaonan Yin, Yuan Yin, Chaoyong Shen, Huijiao Chen, Jiang Wang, Zhaolun Cai, Zhixin Chen, Bo Zhang
Background: Regorafenib is a novel multikinase inhibitor (MKI) approved for use in the treatment of metastatic colorectal cancer (CRC), treatment-refractory gastrointestinal stromal tumors, and other solid tumor malignancies. However, the adverse events (AEs) associated with regorafenib have not been systematically investigated. Hence, we performed a meta-analysis to identify AEs associated with regorafenib in patients with advanced solid tumors. Methods: The databases of PubMed, MEDLINE, and Embase and abstracts presented in American Society of Clinical Oncology annual meetings were searched for relevant publications from January 2004 to September 2017...
2018: OncoTargets and Therapy
Mairah Razi, Humayun Bashir, Aamna Hassan, Imran K Niazi
Although PET-CT scanning is a tremendous advancement in oncology; for accurate interpretation, it is important to understand its limitations. Not all PET-positive lesions are cancerous. Both activated macrophages and metabolically active carcinomas will accumulate F18-FDG. Due to limited specificity of FDG-PET/CT, histologic assessment may be required to establish correct diagnosis. We describe a case of 37-year-old man with non-Hodgkin's lymphoma, who underwent F18-FDG PET/CT at the completion of chemotherapy...
June 2018: JPMA. the Journal of the Pakistan Medical Association
Crystal S Denlinger, Tara Sanft, K Scott Baker, Gregory Broderick, Wendy Demark-Wahnefried, Debra L Friedman, Mindy Goldman, Melissa Hudson, Nazanin Khakpour, Allison King, Divya Koura, Robin M Lally, Terry S Langbaum, Allison L McDonough, Michelle Melisko, Jose G Montoya, Kathi Mooney, Javid J Moslehi, Tracey O'Connor, Linda Overholser, Electra D Paskett, Jeffrey Peppercorn, William Pirl, M Alma Rodriguez, Kathryn J Ruddy, Paula Silverman, Sophia Smith, Karen L Syrjala, Amye Tevaarwerk, Susan G Urba, Mark T Wakabayashi, Phyllis Zee, Nicole R McMillian, Deborah A Freedman-Cass
The NCCN Guidelines for Survivorship provide screening, evaluation, and treatment recommendations for common physical and psychosocial consequences of cancer and cancer treatment to help healthcare professionals who work with survivors of adult-onset cancer in the posttreatment period. This portion of the guidelines describes recommendations regarding the management of anthracycline-induced cardiotoxicity and lymphedema. In addition, recommendations regarding immunizations and the prevention of infections in cancer survivors are included...
October 2018: Journal of the National Comprehensive Cancer Network: JNCCN
Shoko Mori, Cristian Navarrete-Dechent, Tatyana A Petukhova, Erica H Lee, Anthony M Rossi, Michael A Postow, Lara A Dunn, Benjamin R Roman, Vivian T Yin, Daniel G Coit, Travis J Hollmann, Klaus J Busam, Kishwer S Nehal, Christopher A Barker
Background: Tumor board conferences (TBCs) are used by oncologic specialists to review patient cases, exchange knowledge, and discuss options for cancer management. These multidisciplinary meetings are often a cornerstone of treatment at leading cancer centers and are required for accreditation by certain groups, such as the American College of Surgeons' Commission on Cancer. Little is known regarding skin cancer TBCs. The objective of this study was to characterize the structure, function, and impact of existing skin cancer TBCs in the United States...
October 2018: Journal of the National Comprehensive Cancer Network: JNCCN
Sophia Zackrisson, Kristina Lång, Aldana Rosso, Kristin Johnson, Magnus Dustler, Daniel Förnvik, Hannie Förnvik, Hanna Sartor, Pontus Timberg, Anders Tingberg, Ingvar Andersson
BACKGROUND: Digital breast tomosynthesis is an advancement of the mammographic technique, with the potential to increase detection of lesions during breast cancer screening. The main aim of the Malmö Breast Tomosynthesis Screening Trial (MBTST) was to investigate the accuracy of one-view digital breast tomosynthesis in population screening compared with standard two-view digital mammography. METHODS: In this prospective, population-based screening study, of women aged 40-74 years invited to attend national breast cancer screening at Skåne University Hospital, Malmö, Sweden, a random sample was asked to participate in the trial (every third woman who was invited to attend regular screening was invited to participate)...
October 12, 2018: Lancet Oncology
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