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Keywords Magnesium AND (migraine OR mig...

Magnesium AND (migraine OR migraines OR migraineur)

https://read.qxmd.com/read/35812558/stroke-like-migraine-attacks-after-radiation-therapy-smart-syndrome-presenting-with-recurrent-seizures-a-case-study
#21
Neha Panigrahy, Surya Aedma, Matthew Lee
Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare, delayed complication of radiation therapy to the brain. We present a case of a 49-year-old female with a past medical history of malignant neoplasm of the brain status following resection and radiation. She initially presented with increased work of breathing. Initial labs and a chest X-ray were suggestive of aspiration pneumonia leading to sepsis. Upon hospitalization, seizure-like activity was noted. Electroencephalogram showed electrographic seizures originating from the left occipital and parietal lobe...
June 2022: Curēus
https://read.qxmd.com/read/35792970/nutraceuticals-and-migraine-further-strategy-for-the-treatment-of-specific-conditions
#22
JOURNAL ARTICLE
Simone Quintana, Marco Russo, Paola Torelli
Nutraceuticals might be defined as food or dietary supplements that provide medicinal or health benefits. Current preventive treatment of migraine includes nutraceuticals as well as conventional drugs. These non-pharmacological therapies, such as magnesium, coenzyme Q10, feverfew, riboflavin, and phycocyanins, are particularly useful in certain categories of patients (adolescents, pregnant or breastfeeding women, the elderly with complex drug therapy, the patient with contraindication to the usual pharmacological therapies) when a conventional drug therapy cannot be prescribed or may be not well tolerated...
July 6, 2022: Neurological Sciences
https://read.qxmd.com/read/35758197/retinal-nerve-fiber-layer-analysis-in-children-with-migraine-with-and-without-aura-using-optical-coherence-tomography-a-case-control-study
#23
JOURNAL ARTICLE
Daniela Rego-Lorca, Barbara Burgos-Blasco, Cristina Ginés-Gallego, Mario Carrasco-López-Brea, María Teresa de Santos-Moreno, Enrique Santos-Bueso
PURPOSE: To evaluate retinal nerve fiber layer (RNFL) thickness in children with migraine, with and without aura, compared to healthy controls using optical coherence tomography (OCT). METHODS: In this cross-sectional case-control study, patients with a diagnosis of migraine with aura (MwA) or without aura (MwoA) were considered and healthy children were included as controls. Age, sex, duration of migraine, number of episodes per month, duration of episodes, and use of prophylactic treatment with magnesium were recorded...
June 1, 2022: Journal of Pediatric Ophthalmology and Strabismus
https://read.qxmd.com/read/35751375/serum-magnesium-levels-in-children-with-and-without-migraine-a-cross-sectional-study
#24
JOURNAL ARTICLE
Rishab Bhurat, Sarala Premkumar, Ranjith Kumar Manokaran
OBJECTIVE: To study the association between serum magnesium level and migraine in children. METHODS: This cross-sectional study enrolled children aged 5-18 years diagnosed with migraine, and age-and sex-matched controls without a headache disorder. International Classification of Headache Disorders 3 (ICHD-3) was used for the diagnosis of migraine. The association between serum magnesium level and migraine headache was analyzed. RESULTS: A total of 35 children with migraine were enrolled with 35 control subjects...
June 11, 2022: Indian Pediatrics
https://read.qxmd.com/read/35712613/case-report-recurrent-hemiplegic-migraine-attacks-accompanied-by-intractable-hypomagnesemia-due-to-a-de-novo-trpm7-gene-variant
#25
Meifang Lei, Ping Wang, Hong Li, Xiaojun Liu, Jianbo Shu, Qianqian Zhang, Chunquan Cai, Dong Li, Yuqin Zhang
Transient receptor potential melastatin 7 (TRPM7) is a ubiquitously expressed chanzyme comprised of a divalent cation channel permeable to calcium and magnesium and a cytosolic serine-threonine α-kinase domain. TRPM7 has a crucial role in magnesium ion homeostasis and anoxic neuronal death, which was identified as a potential non-glutamate target for hypoxic-ischemic neuronal injury. TRPM7 is implicated in ischemic stroke and hypomagnesemia in many studies, but it has not been associated with disease in the OMIM database...
2022: Frontiers in Pediatrics
https://read.qxmd.com/read/35656968/decreased-plasma-levels-and-dietary-intake-of-minerals-in-women-with-migraine
#26
JOURNAL ARTICLE
Mariele Lino Silva, Laís Bhering Martins, Luana Caroline Dos Santos, Gilberto Simeone Henriques, Antonio Lucio Teixeira, Ana Maria Dos Santos Rodrigues, Adaliene Versiani Matos Ferreira
It has been suggested that an imbalance in mineral levels is involved in the pathophysiology of migraine. However, only a few studies have investigated the circulating levels of mineral in patients with migraine during the pain-free period (i.e. interictal). This study aimed to investigate whether the interictal plasma levels of minerals of women with migraine differ from those of women without migraine (controls). This is a cross-sectional study involving 67 women, of which 38 were diagnosed with migraine and 29 were controls...
June 3, 2022: Nutritional Neuroscience
https://read.qxmd.com/read/35631690/impact-of-magnesium-on-oxytocin-receptor-function
#27
JOURNAL ARTICLE
Vimala N Bharadwaj, Justin Meyerowitz, Bende Zou, Michael Klukinov, Ni Yan, Kaustubh Sharma, David J Clark, Xinmin Xie, David C Yeomans
BACKGROUND AND PURPOSE: The intranasal administration of oxytocin (OT) reduces migraine headaches through activation of the oxytocin receptor (OTR). Magnesium ion (Mg2+) concentration is critical to the activation of the OTR, and a low serum Mg2+ concentration is predictive of a migraine headache. We, therefore, examined the functional impact of Mg2+ concentration on OT-OTR binding efficacy using two complimentary bioassays. EXPERIMENTAL APPROACH: Current clamp recordings of rat trigeminal ganglia (TG) neurons measured the impact of Mg2+ on an OT-induced reduction in excitability...
May 21, 2022: Pharmaceutics
https://read.qxmd.com/read/35609890/lidocaine-infusions-for-refractory-chronic-migraine-a-retrospective-analysis
#28
JOURNAL ARTICLE
Eric S Schwenk, Aaron Walter, Marc C Torjman, Sarah Mukhtar, Harsh T Patel, Bryan Nardone, George Sun, Bhavana Thota, Clinton G Lauritsen, Stephen D Silberstein
INTRODUCTION: Patients with refractory chronic migraine have poor quality of life. Intravenous infusions are indicated to rapidly 'break the cycle' of pain. Lidocaine infusions may be effective but evidence is limited. METHODS: The records of 832 hospital admissions involving continuous multiday lidocaine infusions for migraine were reviewed. All patients met criteria for refractory chronic migraine. During hospitalization, patients received additional migraine medications including ketorolac, magnesium, dihydroergotamine, methylprednisolone, and neuroleptics...
July 2022: Regional Anesthesia and Pain Medicine
https://read.qxmd.com/read/35463839/multimodal-care-for-headaches-lumbopelvic-pain-and-dysmenorrhea-in-a-woman-with-endometriosis-a-case-report
#29
Brett R Martin
Objective: The purpose of this case report is to describe the conservative management of a patient with headaches, lumbopelvic pain, and dysmenorrhea. Clinical Features: A 36-year-old woman presented with intense pelvic and daily lumbar pain. She had difficulty sleeping and focusing and had 3 to 4 headaches per week. Before, during, or after her menses, she would have migraine headaches. During her menses, she experienced severe lumbopelvic pain and dysmenorrhea with moderate bloating, constipation, nausea, and diarrhea...
September 2021: Journal of Chiropractic Medicine
https://read.qxmd.com/read/35356827/the-effects-of-several-abiotic-elicitors-on-the-expression-of-genes-of-key-enzymes-involved-in-the-parthenolide-biosynthetic-pathway-and-its-content-in-feverfew-plant-tanacetum-parthenium-l
#30
JOURNAL ARTICLE
Mahsa Darbahani, Mahdi Rahaie, Asa Ebrahimi, Mahmood Khosrowshahli
Feverfew is an herb used to treat different diseases such as migraine headaches. Due to the economic aspect of its metabolites in the pharmaceutical industry, establishing new approaches to produce the compounds on a large scale is essential. To investigate the effects of stimulators on parthenolide synthesis, feverfew plants were treated with different elicitors, including methyl jasmonate, salicylic acid, NaCl, aluminum oxide, and magnesium aluminate spinel nanoparticles. The expression of genes, E-beta-caryophyllene synthase, Germacrene A synthase, and Costunolide Synthase in the metabolite biosynthesis pathway was examined using qRT-PCR...
March 31, 2022: Natural Product Research
https://read.qxmd.com/read/35112219/artificial-intelligence-analysis-to-explore-synchronize-exercise-cobalamin-and-magnesium-as-new-actors-to-therapeutic-of-migraine-symptoms-a-randomized-placebo-controlled-trial
#31
RANDOMIZED CONTROLLED TRIAL
Hanie Matin, Farzaneh Taghian, Ahmad Chitsaz
INTRODUCTION: Migraine is recognized as a complex neurological disorder that has imposed a social burden. We assessed the signaling pathways and molecular mechanisms based on the in silico analysis and predicted drug candidates by the biomedicine approach. Moreover, we evaluated high-intensity interval training and vitamin B12 + magnesium on women's migraine attacks and inflammatory status. METHODS: This study computed differential gene expression in migraine syndrome and the dimension network parameters visualized by software...
July 2022: Neurological Sciences
https://read.qxmd.com/read/35086408/management-of-pain-using-magnesium-sulphate-a-narrative-review
#32
REVIEW
Hassan Soleimanpour, Farnad Imani, Sanam Dolati, Maryam Soleimanpour, Kavous Shahsavarinia
Pain is one of the most complex and unpleasant sensory and emotional human experiences. Pain relief continues to be a major medical challenge. The application of systemic opioid and regional analgesia techniques has facilitated a decrease in the occurrence and gravity of pain. Magnesium has an evolving role in pain management. Magnesium sulfate (MgSO4), the pharmacological form of magnesium, is a physiological voltage-dependent blocker of N -methyl-D-aspartate (NMDA)-coupled channels. In terms of its antinociceptive role, magnesium blocks calcium influx, which inhibits central sensitization and decreases preexisting pain hypersensitivity...
April 2022: Postgraduate Medicine
https://read.qxmd.com/read/35034669/the-relationship-between-dietary-nutrients-patterns-and-intensity-and-duration-of-migraine-headaches
#33
JOURNAL ARTICLE
Niki Bahrampour, Atieh Mirzababaei, Habib Yarizadeh, Ahmad Mujtaba Barekzai, Faezeh Khorsha, Cain C T Clark, Khadijeh Mirzaei
Migraine is a complicated brain disorder which affects approximately 12 % of the population, whilst the presence of migraine headaches is typically higher in women than men. Several nutrients are posited to improve headache severity. The aim of this study was to investigate the relationship between dietary nutrients patterns and intensity and duration of migraine headaches. This cross-sectional study was conducted with 266 women. Physical activity, general characteristics, anthropometric values and dietary intake were collected...
January 17, 2022: British Journal of Nutrition
https://read.qxmd.com/read/34959985/nutrients-to-improve-mitochondrial-function-to-reduce-brain-energy-deficit-and-oxidative-stress-in-migraine
#34
REVIEW
Michal Fila, Cezary Chojnacki, Jan Chojnacki, Janusz Blasiak
The mechanisms of migraine pathogenesis are not completely clear, but 31 P-nuclear magnetic resonance studies revealed brain energy deficit in migraineurs. As glycolysis is the main process of energy production in the brain, mitochondria may play an important role in migraine pathogenesis. Nutrition is an important aspect of migraine pathogenesis, as many migraineurs report food-related products as migraine triggers. Apart from approved anti-migraine drugs, many vitamins and supplements are considered in migraine prevention and therapy, but without strong supportive evidence...
December 10, 2021: Nutrients
https://read.qxmd.com/read/34811955/evaluation-of-the-pharmacokinetic-interaction-and-safety-of-ubrogepant-coadministered-with-esomeprazole-magnesium
#35
JOURNAL ARTICLE
Ramesh Boinpally, Kaifeng Lu
Ubrogepant is a calcitonin gene-related peptide receptor antagonist for the acute treatment of migraine. Esomeprazole magnesium increases intragastric pH, which may affect oral ubrogepant absorption. This open-label, nonrandomized, crossover trial evaluated esomeprazole magnesium's impact on the pharmacokinetics and safety of coadministered ubrogepant in healthy adults. Participants received ubrogepant 100 mg on day 1, esomeprazole magnesium 40 mg on days 9 to 13, and ubrogepant 100 mg with esomeprazole magnesium 40 mg on day 14...
February 2022: Clinical Pharmacology in Drug Development
https://read.qxmd.com/read/34515155/diagnostic-dilemma-in-an-adolescent-girl-with-an-eating-disorder-intellectual-disability-and-hypomagnesemia
#36
Abdulaziz A Bamhraz, Gijs A C Franken, Jeroen H F de Baaij, Allison Rodrigues, Rosheen Grady, Stephanie Deveau, Rahul Chanchlani
Neurological disorders, including seizures, migraine, depression, and intellectual disability, are frequently associated with hypomagnesemia. Specifically, magnesium (Mg2+) channel transient receptor potential melastatin (TRPM) 6 and TRPM7 are essential for brain function and development. Both channels are also localized in renal and intestinal epithelia and are crucial for Mg2+(re)absorption. Cyclin M2 (CNNM2) is located on the basolateral side of the distal convoluted tubule. In addition, it plays a role in the maintenance of plasma Mg2+ levels along with TRPM6, which is present at the apical level...
August 19, 2021: Nephron
https://read.qxmd.com/read/34444861/migraine-and-its-association-with-hyperactivity-of-cell-membranes-in-the-course-of-latent-magnesium-deficiency-preliminary-study-of-the-importance-of-the-latent-tetany-presence-in-the-migraine-pathogenesis
#37
JOURNAL ARTICLE
Joanna Cegielska, Elżbieta Szmidt-Sałkowska, Wojciech Domitrz, Małgorzata Gaweł, Maria Radziwoń-Zaleska, Izabela Domitrz
So far, there is no consistent and convincing theory explaining the pathogenesis of migraines. Vascular disorders, the effect of oxidative stress on neurons, and the contribution of magnesium-calcium deficiencies in triggering cortical depression and abnormal glutaminergic neurotransmission are taken into account. However, there are no reliable publications confirming the role of dietary deficits of magnesium and latent tetany as factors triggering migraine attacks. The aim of the study was to evaluate the influence of latent magnesium deficiency assessed with the electrophysiological tetany test on the course of migraine...
August 5, 2021: Nutrients
https://read.qxmd.com/read/34393637/-de-novo-migraine-with-aura-in-the-third-trimester-of-pregnancy-a-case-report-and-literature-review
#38
Elena Paškevičiūtė, Diana Bužinskienė, Kristina Ryliškienė
BACKGROUND: Among all headache disorders, migraine has the highest prevalence during gestation. The majority of migraineurs experience improvement during pregnancy, but a few may experience migraine for the first time. This poses a diagnostic challenge in the differential diagnosis between primary and life-threatening secondary headache disorders. Because pregnancy itself is an independent risk factor for secondary headache disorders, it is mandatory to exclude these conditions in order to diagnose migraine...
2021: Acta Medica Lituanica
https://read.qxmd.com/read/34252502/anxiolytic-effect-of-chronic-intake-of-supplemental-magnesium-chloride-in-rat
#39
JOURNAL ARTICLE
Monserrat Macías-Carballo, Sergio Rosas-Navarro, María Leonor López-Meraz, Luis Beltran-Parrazal, Consuelo Morgado-Valle
Evidence suggest that magnesium dietary supplementation has several health benefits including lowering blood pressure, reducing insulin resistance, and improving symptoms of depression, anxiety, and migraine. Here, we aimed to study the effect of chronic magnesium supplementation on anxiety-like behavior in rats by supplementing with magnesium their drinking water for 30 days. Anxiety-like behavior was induced by subcutaneous injection of veratrin 30 min before performing elevated plus maze and open field tests to measure anxiety levels and locomotion, respectively...
September 10, 2021: Behavioural Brain Research
https://read.qxmd.com/read/34163549/the-association-between-hospital-length-of-stay-and-treatment-with-iv-magnesium-in-patients-with-status-migrainosus
#40
JOURNAL ARTICLE
William Hoffman, James Aden, Randall Bossler, Joshua Luster, Morgan Jordan
Status migrainosus (SM) is a subtype of migraine defined by migraine lasting >72 hours and is difficult to treat in clinical practice. Magnesium is commonly used in the treatment of migraine. We conducted a retrospective cohort study to determine if length of admission was associated with IV magnesium therapy in patients with SM. We reviewed the charts of all patients admitted to a large military treatment facility from October 2013 to December 2018 with the admission diagnosis of migraine. There were 333 patients that were reviewed and 141 met the inclusion criteria...
July 2021: Neurohospitalist
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