keyword
https://read.qxmd.com/read/35907108/impact-of-open-irrigated-radiofrequency-catheter-with-contact-force-measurement-on-the-efficacy-and-safety-of-atrial-fibrillation-ablation-a-single-center-direct-comparison
#21
JOURNAL ARTICLE
Simon Schlögl, Klaudia Stella Schlögl, Philipp Bengel, Leonard Bergau, Helge Haarmann, Eva Rasenack, Gerd Hasenfuss, Markus Zabel
BACKGROUND: In atrial fibrillation (AF) patients, catheter ablation of pulmonary veins (PVI) is the most effective therapeutic option to maintain sinus rhythm. To improve successful PVI, contact force-sensing (CF) catheters became routinely available. Previous studies did not clearly show superior clinical efficacy in comparison with non-CF catheters. METHODS: We investigated consecutive patients, who underwent index PVI for AF at our hospital between 2012 and 2018...
July 30, 2022: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://read.qxmd.com/read/35861629/a-mendelian-randomization-study-to-assess-the-genetic-liability-of-gastroesophageal-reflux-disease-for-cardiovascular-diseases-and-risk-factors
#22
JOURNAL ARTICLE
Xingang Sun, Lu Chen, Liangrong Zheng
Observational studies have reported that gastroesophageal reflux disease (GERD) is a risk factor for cardiovascular diseases (CVD); however, the causal inferences between them remain unknown. We conducted a Mendelian randomization (MR) study to estimate the causal associations between GERD and 10 CVD outcomes, as well as 14 cardiovascular risk factors. We used summary statistics from genome-wide association studies for GERD and the FinnGen consortium for CVD. We further investigated whether GERD correlated with cardiovascular risk factors and performed multivariable MR and mediation analyses to estimate the mediating effects of these risk factors on GERD-CVD progression...
July 21, 2022: Human Molecular Genetics
https://read.qxmd.com/read/35845547/recipient-comorbidities-for-prediction-of-primary-graft-dysfunction-chronic-allograft-dysfunction-and-survival-after-lung-transplantation
#23
JOURNAL ARTICLE
Jonas Peter Ehrsam, Macé M Schuurmans, Mirjam Laager, Isabelle Opitz, Ilhan Inci
Since candidates with comorbidities are increasingly referred for lung transplantation, knowledge about comorbidities and their cumulative effect on outcomes is scarce. We retrospectively collected pretransplant comorbidities of all 513 adult recipients transplanted at our center between 1992-2019. Multiple logistic- and Cox regression models, adjusted for donor-, pre- and peri-operative variables, were used to detect independent risk factors for primary graft dysfunction grade-3 at 72 h (PGD3-T72), onset of chronic allograft dysfunction grade-3 (CLAD-3) and survival...
2022: Transplant International
https://read.qxmd.com/read/35624504/perceived-return-to-work-pressure-following-cardiovascular-disease-is-associated-with-age-sex-and-diagnosis-a-nationwide-combined-survey-and-register-based-cohort-study
#24
JOURNAL ARTICLE
Sidsel Marie Bernt Jørgensen, Nina Føns Johnsen, Thomas Alexander Gerds, Stig Brøndum, Thomas Maribo, Gunnar Gislason, Maria Kristiansen
BACKGROUND: Return to work is a key rehabilitation goal for people with cardiovascular disease (CVD) because employment matters to individuals and societies. However, people recovering from CVD often struggle with returning to work and maintaining employment. To identify people in need of vocational counselling, we examined the probability of feeling under pressure to return to work following CVD. METHODS: We conducted a combined survey- and register-based study in a randomly selected, population-based cohort of 10,000 people diagnosed with atrial fibrillation, heart failure, heart valve disease, or ischaemic heart disease in 2018...
May 27, 2022: BMC Public Health
https://read.qxmd.com/read/35399477/the-relationship-between-obstructive-sleep-apnea-osa-and-gastroesophageal-reflux-disease-gerd-in-inpatient-settings-a-nationwide-study
#25
JOURNAL ARTICLE
Ratib Mahfouz, Andriy Barchuk, Adham E Obeidat, Mahmoud M Mansour, David Hernandez, Mohammad Darweesh, Mohammad Aldiabat, Mohannad H Al-Khateeb, Mubarak H Yusuf, Yazan Aljabiri
INTRODUCTION: Several studies identified a link between gastroesophageal reflux disease (GERD) and obstructive sleep apnea (OSA). GERD is a condition in which acid reflux from the stomach to the esophagus causes troublesome symptoms. On the other hand, OSA is defined as a sleep-related breathing disorder in which airflow significantly decreases or ceases due to upper airway obstruction, leading to arousal from sleep. OSA was found to be associated with GERD. In this study, we aim to study the characteristics and concurrent risk factors associated with GERD and OSA in a large population-based study...
March 2022: Curēus
https://read.qxmd.com/read/35354306/latent-pulmonary-vascular-disease-may-alter-the-response-to-therapeutic-atrial-shunt-device-in-heart-failure
#26
JOURNAL ARTICLE
Barry A Borlaug, John Blair, Martin W Bergmann, Heiko Bugger, Dan Burkhoff, Leonhard Bruch, David S Celermajer, Brian Claggett, John G F Cleland, Donald E Cutlip, Ira Dauber, Jean-Christophe Eicher, Qi Gao, Thomas M Gorter, Finn Gustafsson, Chris Hayward, Jan Van der Heyden, Gerd Hasenfuss, Scott L Hummel, David M Kaye, Jan Komtebedde, Joseph M Massaro, Jeremy A Mazurek, Scott McKenzie, Shamir R Mehta, Mark C Petrie, Marco C Post, Ajith Nair, Andreas Rieth, Frank E Silvestry, Scott D Solomon, Jean-Noel Trochu, Dirk J van Veldhuisen, Ralf Westenfeld, Martin B Leon, Sanjiv J Shah
Background: In the REDUCE LAP-HF II trial, implantation of an atrial shunt device did not provide, overall, clinical benefit for patients with heart failure and preserved or mildly reduced ejection fraction (HFpEF/HFmrEF). However, pre-specified analyses identified differences in response in subgroups defined by pulmonary artery systolic pressure during submaximal exercise, right atrial (RA) volume, and sex. Shunt implantation reduces left atrial (LA) pressures but increases pulmonary blood flow, which may be poorly tolerated in patients with pulmonary vascular disease (PVD)...
March 31, 2022: Circulation
https://read.qxmd.com/read/35031169/emergency-department-diagnosis-of-postprocedural-hemorrhagic-cholecystitis-utilizing-point-of-care-ultrasound
#27
JOURNAL ARTICLE
Garrett A Cavaliere, Christine Kositz
BACKGROUND: Hemorrhagic cholecystitis is a rare cause of abdominal pain. Most often described in the setting of blunt abdominal trauma, anticoagulation use, coagulopathy (such as cirrhosis or renal failure), and malignancy (biliary angiosarcoma), this rare condition can be difficult to identify unless high on the differential. With point-of-care ultrasound becoming more commonplace in the emergency department (ED), this tool can be successfully used to make a timely diagnosis in the correct clinical context...
June 2022: Journal of Emergency Medicine
https://read.qxmd.com/read/35022997/recurrent-atrial-arrhythmia-in-a-randomised-controlled-trial-comparing-contact-force-guided-and-contact-force-blinded-ablation-for-typical-atrial-flutter
#28
RANDOMIZED CONTROLLED TRIAL
Mikkel Giehm-Reese, Mads Brix Kronborg, Peter Lukac, Steen Buus Kristiansen, Henrik Kjærulf Jensen, Christian Gerdes, Jens Kristensen, Jan Møller Nielsen, Jens Cosedis Nielsen
BACKGROUND: Contact force (CF)-guided catheter ablation (CA) is a novel technology developed to improve efficacy and reduce complications. In a randomised controlled trial (RCT), we previously documented that after 3 months, rate of persistent conduction block was similar with and without using CF while performing CA for typical atrial flutter (AFL). Clinical effect of CF on recurrent arrhythmia is unknown. Our objective is to study recurrent atrial arrhythmia during 12-month follow-up in a RCT investigating whether CF-guided CA for typical AFL is superior to CF-blinded CA...
April 2022: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://read.qxmd.com/read/34850596/nt-probnp-as-a-marker-for-atrial-fibrillation-and-heart-failure-in-four-observational-outpatient-trials
#29
JOURNAL ARTICLE
Stefanie M Werhahn, Christian Becker, Meinhard Mende, Helge Haarmann, Kathleen Nolte, Ulrich Laufs, Samira Zeynalova, Markus Löffler, Nikolaos Dagres, Daniela Husser, Marcus Dörr, Stefan Gross, Stephan B Felix, Astrid Petersmann, Christoph Herrmann-Lingen, Lutz Binder, Martin Scherer, Gerd Hasenfuß, Burkert Pieske, Frank Edelmann, Rolf Wachter
AIMS: Heart failure (HF) and atrial fibrillation (AF) frequently coexist and are both associated with increased levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP). It is known that AF impairs the diagnostic accuracy of NT-proBNP for HF. The aim of the present study was to compare the diagnostic and predictive accuracy of NT-proBNP for HF and AF in stable outpatients with cardiovascular risk factors. METHODS AND RESULTS: Data were obtained from the DIAST-CHF trial, a prospective cohort study that recruited individuals with cardiovascular risk factors and followed them up for 12 years...
February 2022: ESC Heart Failure
https://read.qxmd.com/read/34687054/remote-magnetic-navigation-versus-manual-catheter-ablation-of-atrial-fibrillation-a-single-center-long-term-comparison
#30
COMPARATIVE STUDY
Simon Schlögl, Klaudia Stella Schlögl, Helge Haarmann, Philipp Bengel, Leonard Bergau, Eva Rasenack, Gerd Hasenfuss, Markus Zabel
BACKGROUND: Data comparing remote magnetic catheter navigation (RMN) with manual catheter navigation (MCN) ablation of atrial fibrillation (AF) is lacking. The aim of the present prospective observational study was to compare the outcome of RMN versus (vs.) MCN ablation of AF with regards to AF recurrence. METHODS: The study comprised 667 consecutive patients with a total of 939 procedures: 287 patients were ablated using RMN, 380 using MCN. RESULTS: There was no significant difference between the groups at baseline...
January 2022: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/34336300/a-large-intrathoracic-hiatal-hernia-as-a-cause-of-complete-heart-block
#31
Ali Abbood, Hareer Al Salihi, Jorge Parellada, Mario Madruga, S J Carlan
Hiatal hernia is a not uncommon anatomic disorder resulting in portions of the bowel occupying space in the thoracic cavity. There are a number of antecedent risk factors including obesity but not hiatal hernias resulting in symptoms. When symptoms do occur, they can include chest pain, nausea, abdominal pain, and gastroesophageal reflux. Cardiac arrhythmias have also been reported as associated conditions resulting from a hiatal hernia. To date, however, a complete heart block secondary to a hiatal hernia has not been reported...
2021: Case Reports in Cardiology
https://read.qxmd.com/read/34315238/impact-of-atrial-fibrillation-on-outcome-in-takotsubo-syndrome-data-from-the-international-takotsubo-registry
#32
MULTICENTER STUDY
Ibrahim El-Battrawy, Victoria L Cammann, Ken Kato, Konrad A Szawan, Davide Di Vece, Aurelio Rossi, Manfred Wischnewsky, Julia Hermes-Laufer, Sebastiano Gili, Rodolfo Citro, Eduardo Bossone, Michael Neuhaus, Jennifer Franke, Benjamin Meder, Milosz Jaguszewski, Michel Noutsias, Maike Knorr, Susanne Heiner, Fabrizio D'Ascenzo, Wolfgang Dichtl, Christof Burgdorf, Behrouz Kherad, Carsten Tschöpe, Annahita Sarcon, Jerold Shinbane, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Wolfgang Koenig, Alexander Pott, Philippe Meyer, Jose David Arroja, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, L Christian Napp, Monika Budnik, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Christina Chan, Paul Bridgman, Daniel Beug, Clément Delmas, Olivier Lairez, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Martin Kozel, Petr Tousek, David E Winchester, Jan Galuszka, Christian Ukena, Gregor Poglajen, Pedro Carrilho-Ferreira, Christian Hauck, Carla Paolini, Claudio Bilato, Yoshio Kobayashi, Abhiram Prasad, Charanjit S Rihal, Kan Liu, P Christian Schulze, Matteo Bianco, Lucas Jörg, Hans Rickli, Gonçalo Pestana, Thanh H Nguyen, Michael Böhm, Lars S Maier, Fausto J Pinto, Petr Widimský, Stephan B Felix, Grzegorz Opolski, Ruediger C Braun-Dullaeus, Wolfgang Rottbauer, Gerd Hasenfuß, Burkert M Pieske, Heribert Schunkert, Holger Thiele, Johann Bauersachs, Hugo A Katus, John D Horowitz, Carlo Di Mario, Thomas Münzel, Filippo Crea, Jeroen J Bax, Thomas F Lüscher, Frank Ruschitzka, Firat Duru, Martin Borggrefe, Jelena R Ghadri, Ibrahim Akin, Christian Templin
Background Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated in a large patient cohort. This study aimed to investigate the prevalence, clinical correlates, and prognostic impact of AF in patients with TTS. Methods and Results Patients with TTS were enrolled from the International Takotsubo Registry, which is a multinational network with 26 participating centers in Europe and the United States...
August 3, 2021: Journal of the American Heart Association
https://read.qxmd.com/read/34160467/reflux-esophagitis-is-associated-with-higher-risks-of-acute-stroke-and-transient-ischemic-attacks-in-patients-hospitalized-with-atrial-fibrillation-a-nationwide-inpatient-sample-analysis
#33
JOURNAL ARTICLE
Yi Jiang, Konstantinos Damiris, Giselle Suero-Abreu, Binghong Xu, Sushil Ahlawat
Reflux esophagitis (RE) is a subset of gastroesophageal reflux disease (GERD) with endoscopic evidence of esophageal inflammation, which has been linked to an increased incidence of atrial fibrillation (AF). However, data on the effect of RE on patient outcomes is limited. We sought to examine the potential association of RE with outcomes of patients with AF in a nationwide study.The National Inpatient Sample (NIS) database was queried to identify hospitalized adult patients with AF and RE between 2010 and 2014...
June 25, 2021: Medicine (Baltimore)
https://read.qxmd.com/read/33647366/discontinuation-of-oral-anticoagulation-and-risk-of-stroke-and-death-after-ablation-for-typical-atrial-flutter-a-nation-wide-danish-cohort-study
#34
JOURNAL ARTICLE
Mikkel Giehm-Reese, Martin Nygård Johansen, Mads Brix Kronborg, Henrik Kjærulf Jensen, Christian Gerdes, Jens Kristensen, Arne Johannessen, Peter Karl Jacobsen, Mogens Stig Djurhuus, Peter Steen Hansen, Sam Riahi, Jens Cosedis Nielsen
INTRODUCTION: Oral anticoagulation (OAC) is indicated for patients with atrial fibrillation (AF) and atrial flutter (AFL) with a CHA2 DS2 -VASc score ≥ 2 for men and ≥3 for women. This is regardless of successful catheter ablation for their arrhythmia. Studies have mainly focused on AF, and little is known regarding use of OAC in AFL patients following catheter ablation. PURPOSE: To describe discontinuation of OAC in a national cohort of patients who have undergone first-time cavo-tricuspid isthmus ablation (CTIA) for AFL...
June 15, 2021: International Journal of Cardiology
https://read.qxmd.com/read/33624011/all-cause-mortality-and-location-of-death-in-patients-with-established-cardiovascular-disease-before-during-and-after-the-covid-19-lockdown-a-danish-nationwide-cohort-study
#35
JOURNAL ARTICLE
Jawad H Butt, Emil L Fosbøl, Thomas A Gerds, Charlotte Andersson, Kristian Kragholm, Tor Biering-Sørensen, Julie Andersen, Mathew Phelps, Mikkel Porsborg Andersen, Gunnar Gislason, Christian Torp-Pedersen, Lars Køber, Morten Schou
BACKGROUND: On 13 March 2020, the Danish authorities imposed extensive nationwide lockdown measures to prevent the spread of the coronavirus disease 2019 (COVID-19) and reallocated limited healthcare resources. We investigated mortality rates, overall and according to location, in patients with established cardiovascular disease before, during, and after these lockdown measures. METHODS AND RESULTS: Using Danish nationwide registries, we identified a dynamic cohort comprising all Danish citizens with cardiovascular disease (i...
April 14, 2021: European Heart Journal
https://read.qxmd.com/read/33168641/catheter-ablation-and-mortality-stroke-and-heart-failure-readmission-with-atrial-fibrillation
#36
JOURNAL ARTICLE
Jannik Langtved Pallisgaard, Morten Lock Hansen, Anne-Marie Schjerning, Arne Johannessen, Thomas Alexander Gerds, Finn Gustafsson, Gunnar Hilmar Gislason, Chriatian Torp-Pedersen, Peter Karl Jacobsen, Søren Lund Kristensen, Lars Koeber, Anders Munch, Morten Schou
BACKGROUND: Recent randomised clinical trials have suggested prognostic benefits of catheter ablation in highly selected patients with atrial fibrillation (AF) and heart failure (HF). OBJECTIVES: This study sought to identify the treatment effect associated with catheter ablation in a broad population of patients with AF and HF. METHODS: Through nationwide administrative registers in Denmark, we estimated the 2-year average treatment effect (ATE) of catheter ablation for AF on a composite endpoint of HF readmission, stroke and all-cause mortality at 1-year and 5-year landmark analyses...
November 2020: Open Heart
https://read.qxmd.com/read/33140384/clinical-outcomes-of-cryoballoon-ablation-for-pulmonary-vein-isolation-impact-of-intraprocedural-heart-rhythm
#37
JOURNAL ARTICLE
Bruno Reissmann, Christian-H Heeger, Karena Opitz, Michael Schlüter, Peter Wohlmuth, Laura Rottner, Thomas Fink, Jin-Hong Gerds-Li, Shibu Mathew, Christine Lemes, Tilman Maurer, Feifan Ouyang, Karl-Heinz Kuck, Andreas Rillig, Doreen Schöppenthau, Andreas Metzner
BACKGROUND: The current study sought to assess the impact of the intraprocedural heart rhythm (sinus rhythm [SR] vs. atrial fibrillation [AF]) on acute procedural characteristics, durability of pulmonary vein isolation (PVI) and long-term clinical outcomes of cryoballoon (CB) ablation. METHODS: A total of 195 patients with symptomatic paroxysmal (n = 136) or persistent AF (n = 59) underwent CB-based PVI. Ablation procedures were either performed in SR (SR group; n = 147) or during AF (AF group; n = 48)...
November 3, 2020: Cardiology Journal
https://read.qxmd.com/read/33107909/cardiovascular-comorbidities-as-predictors-for-severe-covid-19-infection-or-death
#38
JOURNAL ARTICLE
Matthew Phelps, Daniel Mølager Christensen, Thomas Gerds, Emil Fosbøl, Christian Torp-Pedersen, Morten Schou, Lars Køber, Kristian Kragholm, Charlotte Andersson, Tor Biering-Sørensen, Helle Collatz Christensen, Mikkel Porsborg Andersen, Gunnar Gislason
AIMS: Pre-existing cardiovascular diseases (CVDs) have been proposed to identify patients at higher risk of adverse coronavirus disease 2019 (COVID-19) outcomes, but existing evidence is conflicting. Thus, it is unclear whether pre-existing CVDs are independently important predictors for severe COVID-19. METHODS AND RESULTS: In a nationwide Danish cohort of hospital-screened COVID-19 patients aged ≥40, we investigated if pre-existing CVDs predict the 30-day risk of (i) composite outcome of severe COVID-19 and (ii) all-cause mortality...
March 15, 2021: European Heart Journal. Quality of Care & Clinical Outcomes
https://read.qxmd.com/read/33073633/repeat-pulmonary-vein-isolation-in-patients-with-atrial-fibrillation-low-ablation-index-is-associated-with-increased-risk-of-recurrent-arrhythmia
#39
JOURNAL ARTICLE
Steen B Kristiansen, Ajmal Shafaq, Bawer J Tofig, Christian Gerdes, Henrik K Jensen, Jens Kristensen, Erik T Parner, Peter Lukac
We aimed to investigate the predictors of recurrent arrhythmia after repeated pulmonary vein isolation (PVI) performed in the era of contact force without additional substrate ablation. One of the predictors studied, ablation index (AI), incorporates power, contact force, and time in a weighted formula and is reported to predict lesion size in animals. Design . Consecutive patients ( n  = 108) undergoing repeat PVI without additional substrate modification using a contact force sensing catheter were included retrospectively at a tertiary center...
October 19, 2020: Scandinavian Cardiovascular Journal: SCJ
https://read.qxmd.com/read/33062508/gastroesophageal-reflux-and-its-association-with-atrial-fibrillation-a-traditional-review
#40
REVIEW
Alaa Mohamed, Diego Ochoa Crespo, Gurleen Kaur, Ibtisam Ashraf, Mercedes Maria Peck, Ruchira Maram, Bilal Haider Malik
Atrial fibrillation (AF) is a common arrhythmia, and gastroesophageal reflux disease (GERD) is a common gastroenterology disease; both are highly encountered daily in clinical practice. Since both share common predisposing factors, we can conclude that there is a link between them. To date, the precise mechanism of reflux disease as a possible cause of atrial fibrillation remains uncertain. However, some possibilities can be postulated, such as the inflammation process, and sympathovagal imbalance represents the main factors for how GERD can initiate AF...
September 11, 2020: Curēus
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