keyword
MENU ▼
Read by QxMD icon Read
search

Bipolar disorder fmri

keyword
https://www.readbyqxmd.com/read/28415008/bipolar-mood-state-reflected-in-cortico-amygdala-resting-state-connectivity-a-cohort-and-longitudinal-study
#1
Roscoe O Brady, Allison Margolis, Grace A Masters, Matcheri Keshavan, Dost Öngür
BACKGROUND: Using resting-state functional magnetic resonance imaging (rsfMRI), we previously compared cohorts of bipolar I subjects in a manic state to those in a euthymic state to identify mood state-specific patterns of cortico-amygdala connectivity. Our results suggested that mania is reflected in the disruption of emotion regulation circuits. We sought to replicate this finding in a group of subjects with bipolar disorder imaged longitudinally across states of mania and euthymia METHODS: We divided our subjects into three groups: 26 subjects imaged in a manic state, 21 subjects imaged in a euthymic state, and 10 subjects imaged longitudinally across both mood states...
March 28, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28392151/effects-of-risk-for-bipolar-disorder-on-brain-function-a-twin-and-family-study
#2
Genichi Sugihara, Fergus Kane, Marco M Picchioni, Christopher A Chaddock, Eugenia Kravariti, Sridevi Kalidindi, Fruhling Rijsdijk, Timothea Toulopoulou, Vivienne A Curtis, Colm McDonald, Robin M Murray, Philip McGuire
Bipolar disorder (BPD) is associated with altered regional brain function during the performance of cognitive tasks. The relative contribution of genetic and environmental risk factors for BPD to these changes has not yet been quantified. We sought to address this issue in a functional neuroimaging study of people who varied in their risk for BPD. Functional magnetic resonance imaging was used to study 124 subjects (29 twin and 9 sibling pairs with at least one member with BPD, and 24 healthy twin pairs) performing a working memory task...
April 6, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28367127/alterations-of-intrinsic-brain-connectivity-patterns-in-depression-and-bipolar-disorders-a-critical-assessment-of-magnetoencephalography-based-evidence
#3
REVIEW
Golnoush Alamian, Ana-Sofía Hincapié, Etienne Combrisson, Thomas Thiery, Véronique Martel, Dmitrii Althukov, Karim Jerbi
Despite being the object of a thriving field of clinical research, the investigation of intrinsic brain network alterations in psychiatric illnesses is still in its early days. Because the pathological alterations are predominantly probed using functional magnetic resonance imaging (fMRI), many questions about the electrophysiological bases of resting-state alterations in psychiatric disorders, particularly among mood disorder patients, remain unanswered. Alongside important research using electroencephalography (EEG), the specific recent contributions and future promise of magnetoencephalography (MEG) in this field are not fully recognized and valued...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28348512/using-dual-regression-to-investigate-network-shape-and-amplitude-in-functional-connectivity-analyses
#4
Lisa D Nickerson, Stephen M Smith, Döst Öngür, Christian F Beckmann
Independent Component Analysis (ICA) is one of the most popular techniques for the analysis of resting state FMRI data because it has several advantageous properties when compared with other techniques. Most notably, in contrast to a conventional seed-based correlation analysis, it is model-free and multivariate, thus switching the focus from evaluating the functional connectivity of single brain regions identified a priori to evaluating brain connectivity in terms of all brain resting state networks (RSNs) that simultaneously engage in oscillatory activity...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28337552/clinical-utility-of-resting-state-functional-connectivity-magnetic-resonance-imaging-for-mood-and-cognitive-disorders
#5
REVIEW
T Takamura, T Hanakawa
Although functional magnetic resonance imaging (fMRI) has long been used to assess task-related brain activity in neuropsychiatric disorders, it has not yet become a widely available clinical tool. Resting-state fMRI (rs-fMRI) has been the subject of recent attention in the fields of basic and clinical neuroimaging research. This method enables investigation of the functional organization of the brain and alterations of resting-state networks (RSNs) in patients with neuropsychiatric disorders. Rs-fMRI does not require participants to perform a demanding task, in contrast to task fMRI, which often requires participants to follow complex instructions...
March 23, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28294459/identifying-dynamic-functional-connectivity-biomarkers-using-gig-ica-application-to-schizophrenia-schizoaffective-disorder-and-psychotic-bipolar-disorder
#6
Yuhui Du, Godfrey D Pearlson, Dongdong Lin, Jing Sui, Jiayu Chen, Mustafa Salman, Carol A Tamminga, Elena I Ivleva, John A Sweeney, Matcheri S Keshavan, Brett A Clementz, Juan Bustillo, Vince D Calhoun
Functional magnetic resonance imaging (fMRI) studies have shown altered brain dynamic functional connectivity (DFC) in mental disorders. Here, we aim to explore DFC across a spectrum of symptomatically-related disorders including bipolar disorder with psychosis (BPP), schizoaffective disorder (SAD), and schizophrenia (SZ). We introduce a group information guided independent component analysis procedure to estimate both group-level and subject-specific connectivity states from DFC. Using resting-state fMRI data of 238 healthy controls (HCs), 140 BPP, 132 SAD, and 113 SZ patients, we identified measures differentiating groups from the whole-brain DFC and traditional static functional connectivity (SFC), separately...
May 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28262138/prefrontal-oxygenation-during-verbal-fluency-and-cognitive-function-in-adolescents-with-bipolar-disorder-type-ii
#7
Yasuki Ono, Mitsuru Kikuchi, Hideo Nakatani, Masako Murakami, Manami Nishisaka, Tomoko Muramatsu, Toshio Munesue, Yoshio Minabe
Evaluation of depressive states in children can be challenging. Most of the studies that have investigated cognitive function and cerebral blood volume changes using functional MRI (fMRI) in bipolar disorder (BD) have been confined to BDI or heterogeneous cohorts with attention-deficit/hyperactivity disorder (ADHD). This study investigated cognitive functions in adolescents with BDII and without ADHD using near-infrared spectroscopy (NIRS) and a Das-Naglieri Cognitive Assessment System (DN-CAS). Ten patients with BDII and without ADHD symptoms and 10 age- and gender-matched healthy controls were enrolled in the present study...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28205606/differential-abnormal-pattern-of-anterior-cingulate-gyrus-activation-in-unipolar-and-bipolar-depression-an-fmri-and-pattern-classification-approach
#8
Christian Bürger, Ronny Redlich, Dominik Grotegerd, Susanne Meinert, Katharina Dohm, Ilona Schneider, Dario Zaremba, Katharina Förster, Judith Alferink, Jens Bölte, Walter Heindel, Harald Kugel, Volker Arolt, Udo Dannlowski
Distinguishing bipolar disorder from major depressive disorder is a major challenge in psychiatric treatment. Consequently, there has been growing interest in identifying neuronal biomarkers of disorder-specific pathophysiological processes to differentiate affective disorders. Thirty-six depressed bipolar patients, 36 depressed unipolar patients and 36 matched healthy controls participated in an fMRI-experiment. Emotional faces served as stimuli in a matching task. We investigated neural activation towards angry, fearful and happy faces focusing on prototypical regions related to emotion processing, ie the amygdala and the anterior cingulate gyrus (ACG)...
February 16, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28199893/decreased-cingulate-cortex-activation-during-cognitive-control-processing-in-bipolar-disorder
#9
Staci A Gruber, M Kathryn Dahlgren, Kelly A Sagar, Atilla Gonenc, Lesley Norris, Bruce M Cohen, Dost Ongur, Kathryn E Lewandowski
BACKGROUND: Cognitive deficits are well-documented in patients with bipolar disorder (BPD) and may impact the efficacy of psychotherapy. Cognitive control, a form of executive functioning, is often used therapeutically to shift patients' thoughts and behaviors from automatic, maladaptive responses to adaptive coping strategies. This study examined cognitive control processing in patients with BPD using the Multi-Source Interference Task (MSIT). METHOD: Twenty-nine patients diagnosed with BPD and 21 healthy control (HC) subjects completed the MSIT with concurrent functional magnetic resonance imaging (fMRI)...
February 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28169089/meta-analysis-of-functional-magnetic-resonance-imaging-studies-of-timing-and-cognitive-control-in-schizophrenia-and-bipolar-disorder-evidence-of-a-primary-time-deficit
#10
REVIEW
Irene Alústiza, Joaquim Radua, Marta Pla, Raquel Martin, Felipe Ortuño
Schizophrenia (SZ) and Bipolar Disorder (BD) are associated with deficits in both timing and cognitive control functions. However, the underlying neurological dysfunctions remain poorly understood. The main goal of this study was to identify brain structures activated both by increases in cognitive activity and during timing tasks in patients with SZ and BD relative to controls. We conducted two signed differential mapping (SDM) meta-analyses of functional magnetic resonance imaging studies assessing the brain response to increasing levels of cognitive difficulty: one concerned SZ, and the other BD patients...
February 3, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28130184/amygdala-prefrontal-cortex-resting-state-functional-connectivity-varies-with-first-depressive-or-manic-episode-in-bipolar-disorder
#11
Shengnan Wei, Haiyang Geng, Xiaowei Jiang, Qian Zhou, Miao Chang, Yifang Zhou, Ke Xu, Yanqing Tang, Fei Wang
BACKGROUND: Bipolar disorder (BD) is one of the most complex mental illnesses, characterized by interactive depressive and manic states that are 2 contrary symptoms of disease states. The bilateral amygdala and prefrontal cortex (PFC) appear to play critical roles in BD; however, abnormalities seem to manifest differently in the 2 states and may provide further insight into underlying mechanisms. METHODS: Sixteen participants with first-episode depressive and 13 participants with first-episode manic states of bipolar disorder as well as 30 healthy control (HC) participants underwent resting-state functional magnetic resonance imaging (fMRI)...
January 25, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28112029/two-patterns-of-anterior-insular-cortex-functional-connectivity-in-bipolar-disorder-and-schizophrenia
#12
Jian Li, Yanqing Tang, Fay Womer, Guoguang Fan, Qian Zhou, Wenge Sun, Ke Xu, Fei Wang
OBJECTIVES: Bipolar disorder (BD) and schizophrenia (SZ) share structural abnormalities in the anterior insula cortex (AIC). The AIC appears to have a crucial role in emotional processing and regulation and cognitive control in BD and SZ. METHODS: Forty-six participants with BD, 68 with SZ and 66 healthy controls (HC) underwent functional magnetic resonance imaging scanning. Resting-state functional connectivity (rsFC) from AIC subregions (ventral and dorsal) was compared among the three groups...
January 23, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/28067006/addressing-reverse-inference-in-psychiatric-neuroimaging-meta-analyses-of-task-related-brain-activation-in-common-mental-disorders
#13
Emma Sprooten, Alexander Rasgon, Morgan Goodman, Ariella Carlin, Evan Leibu, Won Hee Lee, Sophia Frangou
Functional magnetic resonance imaging (fMRI) studies in psychiatry use various tasks to identify case-control differences in the patterns of task-related brain activation. Differently activated regions are often ascribed disorder-specific functions in an attempt to link disease expression and brain function. We undertook a systematic meta-analysis of data from task-fMRI studies to examine the effect of diagnosis and study design on the spatial distribution and direction of case-control differences on brain activation...
April 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28049082/catechol-o-methyltransferase-val-108-158-met-polymorphism-affects-fronto-limbic-connectivity-during-emotional-processing-in-bipolar-disorder
#14
B Vai, M Riberto, S Poletti, I Bollettini, C Lorenzi, C Colombo, F Benedetti
Catechol-O-methyltransferase (COMT) inactivates catecholamines, Val/Val genotype was associated to an increased amygdala (Amy) response to negative stimuli and can influence the symptoms severity and the outcome of bipolar disorder, probably mediated by the COMT polymorphism (rs4680) interaction between cortical and subcortical dopaminergic neurotransmission. The aim of this study is to explore how rs4680 and implicit emotional processing of negative emotional stimuli could interact in affecting the Amy connectivity in bipolar depression...
March 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28031150/functional-dysconnection-of-the-inferior-frontal-gyrus-in-young-people-with-bipolar-disorder-or-at-genetic-high-risk
#15
Gloria Roberts, Anton Lord, Andrew Frankland, Adam Wright, Phoebe Lau, Florence Levy, Rhoshel K Lenroot, Philip B Mitchell, Michael Breakspear
BACKGROUND: Bipolar disorder (BD) is characterized by a dysregulation of affect and impaired integration of emotion with cognition. These traits are also expressed in probands at high genetic risk of BD. The inferior frontal gyrus (IFG) is a key cortical hub in the circuits of emotion and cognitive control, and it has been frequently associated with BD. Here, we studied resting-state functional connectivity of the left IFG in participants with BD and in those at increased genetic risk...
August 18, 2016: Biological Psychiatry
https://www.readbyqxmd.com/read/28025071/th17-cells-correlate-positively-to-the-structural-and-functional-integrity-of-the-brain-in-bipolar-depression-and-healthy-controls
#16
Sara Poletti, Harm de Wit, Elena Mazza, Annemarie J M Wijkhuijs, Clara Locatelli, Veronica Aggio, Cristina Colombo, Francesco Benedetti, Hemmo A Drexhage
Abnormalities of T cell-mediated immune activation, in the absence of active somatic immune diseases, have consistently been reported in mood disorders. Apart from being important players in the regulation of cells of the immune system, T cells are essential for normal brain development. We here report studies on the relationship between circulating levels of T helper cells and structural and functional brain imaging in depressed bipolar patients. Since the CCL20-CCR6 axis is an important entry to the brain we differentiated the various T helper cell subpopulations on the basis of their chemokine receptor expression...
December 23, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28002659/trait-related-cortical-subcortical-dissociation-in-bipolar-disorder-analysis-of-network-degree-centrality
#17
Qian Zhou, Fay Y Womer, Lingtao Kong, Feng Wu, Xiaowei Jiang, Yifang Zhou, Dahai Wang, Chuan Bai, Miao Chang, Guoguang Fan, Ke Xu, Yong He, Yanqing Tang, Fei Wang
BACKGROUND: Bipolar disorder is a systemic brain disorder. Accumulated evidence suggested that cortical-subcortical imbalance could be a trait-related pathogenic factor of bipolar disorder. Degree centrality, a robust index of focal connectivity in which the number of direct connections from one node to all nodes is counted, has not previously been studied in bipolar disorder as a whole. METHODS: Resting state functional magnetic resonance imaging was performed on 52 patients with DSM-IV bipolar I disorder and 70 healthy controls recruited between September 2009 and July 2014...
December 20, 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27993231/neural-markers-in-pediatric-bipolar-disorder-and-familial-risk-for-bipolar-disorder
#18
Jillian Lee Wiggins, Melissa A Brotman, Nancy E Adleman, Pilyoung Kim, Caroline G Wambach, Richard C Reynolds, Gang Chen, Kenneth Towbin, Daniel S Pine, Ellen Leibenluft
OBJECTIVE: Bipolar disorder (BD) is highly heritable. Neuroimaging studies comparing unaffected youth at high familial risk for BD (i.e., those with a first-degree relative with the disorder; termed "high-risk" [HR]) to "low-risk" (LR) youth (i.e., those without a first-degree relative with BD) and to patients with BD may help identify potential brain-based markers associated with risk (i.e., regions where HR+BD≠LR), resilience (HR≠BD+LR), or illness (BD≠HR+LR). METHOD: During functional magnetic resonance imaging (fMRI), 99 youths (i...
January 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/27990494/relationships-between-altered-functional-magnetic-resonance-imaging-activation-and-cortical-thickness-in-patients-with-euthymic-bipolar-i-disorder
#19
Shantanu H Joshi, Nathalie Vizueta, Lara Foland-Ross, Jennifer D Townsend, Susan Y Bookheimer, Paul M Thompson, Katherine L Narr, Lori L Altshuler
BACKGROUND: Performance during cognitive control functional magnetic resonance imaging (fMRI) tasks are associated with frontal lobe hypoactivation in patients with bipolar disorder, even while euthymic. Here, we study the structural underpinnings for this functional abnormality simultaneously with brain activation data. METHODS: In a sample of ninety adults (45 with inter-episode Bipolar I disorder and 45 healthy controls), we explored whether abnormal functional activation patterns in bipolar euthymic subjects during a Go-NoGo fMRI task are associated with regional deficits in cortical gray matter thickness in the same regions...
November 2016: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/27922632/a-phenome-wide-examination-of-neural-and-cognitive-function
#20
R A Poldrack, E Congdon, W Triplett, K J Gorgolewski, K H Karlsgodt, J A Mumford, F W Sabb, N B Freimer, E D London, T D Cannon, R M Bilder
This data descriptor outlines a shared neuroimaging dataset from the UCLA Consortium for Neuropsychiatric Phenomics, which focused on understanding the dimensional structure of memory and cognitive control (response inhibition) functions in both healthy individuals (130 subjects) and individuals with neuropsychiatric disorders including schizophrenia (50 subjects), bipolar disorder (49 subjects), and attention deficit/hyperactivity disorder (43 subjects). The dataset includes an extensive set of task-based fMRI assessments, resting fMRI, structural MRI, and high angular resolution diffusion MRI...
December 6, 2016: Scientific Data
keyword
keyword
17102
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"