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Hye Young Jeon, Kwang Won Seo, Yeong Bin Kim, Dong Kyu Kim, Shin Woo Kim, Young Ju Lee
Integrated broiler operations, which control and operate vertically through all phases of the chicken industry, have applied biosecurity and sanitation practices, housing technologies, feeding regimens, and antibiotic applications in different ways to improve food safety. The objective of this study was to compare the prevalence and antimicrobial resistance profiles of Salmonella isolates recovered from 6 different integrated broiler operations and to analyze the characteristics of extended-spectrum β-lactamase (ESBL)- and plasmid-mediated AmpC β-lactamase (pAmpC)-producing Salmonella isolates...
December 7, 2018: Poultry Science
Lidya Ketema, Zerihun Ketema, Bitsu Kiflu, Haile Alemayehu, Yitagele Terefe, Mohammed Ibrahim, Tadesse Eguale
Salmonella is one of the top causes of foodborne bacterial illnesses in humans. The primary sources of human Salmonella infection are food producing animals such as cattle, poultry, and swine. A cross-sectional study was undertaken to estimate the prevalence and to determine the serovar distribution and antimicrobial susceptibility profiles of Salmonella spp. isolated from fecal (n=567) and carcass swab (n=159) samples of slaughtered cattle at Addis Ababa Abattoir Enterprise and Kara'alo PLC, Abattoirs, in Addis Ababa, Ethiopia between January 2014 and April 2015...
2018: BioMed Research International
Kara Nadeau, Michele Brule
Rothmund-Thomson syndrome is a genetic disorder with characteristic findings in childhood as well as a predisposition to osteosarcoma, skin cancer, and hematological malignancy. We present the first reported case of duodenal malignancy in a patient with Rothmund-Thompson syndrome. An enlarged Virchow's node was noted and an advanced duodenal adenocarcinoma was diagnosed shortly thereafter. The features of Rothmund-Thomson syndrome are discussed, as well as current management and screening guidelines for duodenal adenocarcinoma...
2018: Case Reports in Genetics
Lance H Rodan, Kwame Anyane-Yeboa, Karen Chong, Jolien S Klein Wassink-Ruiter, Ashley Wilson, Lacey Smith, Sanjeev V Kothare, Farrah Rajabi, Susan Blaser, Min Ni, Ralph J DeBerardinis, Annapurna Poduri, Gerard T Berry
Polyamines serve a number of vital functions in humans, including regulation of cellular proliferation, intracellular signaling, and modulation of ion channels. Ornithine decarboxylase 1 (ODC1) is the rate-limiting enzyme in endogenous polyamine synthesis. In this report, we present four patients with a distinct neurometabolic disorder associated with de novo heterozygous, gain-of-function variants in the ODC1 gene. This disorder presents with global developmental delay, ectodermal abnormalities including alopecia, absolute or relative macrocephaly, and characteristic facial dysmorphisms...
November 26, 2018: American Journal of Medical Genetics. Part A
Ryohei Otani, Takeo Uzuka, Hadzki Matsuda, Fumi Higuchi, Phyo Kim, Keisuke Ueki
Brain invasion by chronic lymphocytic leukemia (CLL) is very rare, and only a handful of cases have been reported. We here report a case of 61-year-old woman who had been treated for CLL for 14 years presenting with a progressive mental disturbance. Magnetic resonance imaging (MRI) showed discontinuous ring-enhancing lesions compatible with the "open ring" sign, which was considered a demyelinating disorder, in both the frontal lobes. However, on histological examination of the biopsied specimen, infiltration of small lymphocytes positive for CD5, CD20, and CD23, indicating brain invasion by CLL, was seen...
November 25, 2018: Neuropathology: Official Journal of the Japanese Society of Neuropathology
Mª Jesús Fernández Aceñero, Ana Caso Viesca, Cristina Díaz Del Arco
INTRODUCTION: In the 19th century Virchow described that metastasis to left supraclavicular lymph nodes (SLN) could originate in neoplasms located under the diaphragm. In the same way, right SLN metastasis are usually thought to arise from thoracic neoplasms. Our aims are to review our experience with metastatic SLN diagnosed by fine-needle aspiration cytology (FNAC) and to discuss the location of the primary in these cases. METHODS: We have reviewed all lymph node FNACs diagnosed in a single tertiary hospital between 2010 and 2017 and we have included all cases of metastatic SLN...
November 23, 2018: Diagnostic Cytopathology
Peter Yat-Ming Woo, Eric Cheung, James Ting-Fong Zhuang, Hoi-Tung Wong, Kwong-Yau Chan
Cerebral perivascular spaces (PVSs), otherwise known as Virchow-Robin spaces, are interstitial fluid-filled channels, <2 mm in diameter that form around arterial perforators as they course from the cortex into the brain parenchyma. In contrast, a giant tumefactive PVS is a rare entity comprising of clusters of such channels larger than 15mm resembling a neoplastic process as the name suggests. We report a 55-year-old male who presented with unsteady gait, cognitive decline, and left lower limb weakness for 6 months...
October 2018: Asian Journal of Neurosurgery
Sinem Uğur, Nefise Akçelik, Fatma Neslihan Yüksel, Neslihan Taşkale Karatuğ, Mustafa Akçelik
In this study, the effects of dam and seqA genes on the formation of pellicle and biofilm was determined using five different Salmonella serovars S. Group C1 (DMC2 encoded), S. Typhimurium (DMC4 encoded), S. Virchow (DMC11 encoded), S. Enteritidis (DMC22 encoded), and S. Montevideo (DMC89 encoded). dam and seqA mutants in Salmonella serovars were performed by the single step lambda red recombination method. The mutants obtained were examined according to the properties of biofilm on the polystyrene surfaces and the pellicle formation on the liquid medium...
November 15, 2018: Pathogens and Global Health
Jason Cui, Brian Kirkby
INTRODUCTION: Acute mesenteric venous thrombosis is a rare but potentially fatal condition with superior mesenteric vein being the most common site of thrombosis development [1]. It is more common in patients with underlying disorders which cause disruptions to Virchow's Triad of hypercoagulability, stasis and endothelial injury. The disease is often associated with intestinal ischemia in its acute form, further complicating its management. PRESENTATION OF CASE: We present a case of acute superior mesenteric venous thrombosis resulting in jejunal ischemia in a 60-year-old Caucasian male with possible ulcerative colitis...
October 29, 2018: International Journal of Surgery Case Reports
Ahsan A Khan, Gregory Y H Lip
Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia, and is associated with significant morbidity and mortality. There is plenty of evidence available to support the presence of a prothrombotic or hypercoagulable state in AF, but the contributory factors are multifactorial and cannot simply be explained by blood stasis.Abnormal changes in atrial wall (anatomical and structural, as 'vessel wall abnormalities'), the presence of spontaneous echo contrast to signify abnormal changes in flow and stasis ('flow abnormalities") and abnormal changes in coagulation, platelet and other pathophysiologic pathways ('abnormalities of blood constituents') are well documented in AF...
November 2, 2018: Cardiovascular Research
Arvind Krishnamurthy
Lymph node metastasis is widely believed to be one of the most powerful prognostic factors influencing the outcomes of many solid cancers, including esophageal cancers. The left supraclavicular node, famously described as the Virchow's node, is occasionally involved in patients with advanced gastrointestinal cancers. Virchow node involvement is considered "nonregional" in all the gastrointestinal cancers, except in esophageal cancers. On the other hand, axillary lymph node metastases (ALNMs) are considered "nonregional" in all gastrointestinal cancers, including esophageal cancers...
October 2018: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
Junya Morita, Toru Aoyama, Shinya Amano, Yukio Maezawa, Sho Sawazaki, Masakatsu Numata, Tsutomu Sato, Yukihiro Ozawa, Takashi Oshima, Norio Yukawa, Yasushi Rino, Munetaka Masuda
A 59-year-old woman was diagnosed with advanced gastric cancer with para-aortic and Virchow's lymph node metastases (L, Less, type 2, tub1, cT3N2H0P0M1[LYM: #16, Virchow's]). Four courses of S-1(80mg/m / 2, days 1-21)and CDDP(60mg/ m2, day 8)were administered. After the chemotherapy, CT showed that the primary tumor and para-aortic and Virchow's lymph nodes had reduced in size. The clinical stage was ycT3N1H0P0M0, stage III A. The patient underwent distalgastrectomy, D2 dissection, and sampling of the para-aortic lymph nodes(#16b1lat, #16a2int)...
October 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Eigo Kurayama, Kinro Sasaki, Hitoshi Satomura, Haruka Yokoyama, Maiko Kikuchi, Tsukasa Kubo, Nozomi Ueno, Kichiro Otsuka, Shinichi Onodera, Jun Ito, Masanobu Nakajima, Satoru Yamaguchi, Kazuhito Miyachi, Takashi Tsuchioka, Hiroyuki Kato
A 41-year-old woman with type 3 advanced gastric cancer and Virchow lymph node, para-aortic lymph node, and multiple bone metastases was diagnosed with U-less cType 3 cT4aN3M1, cStage IV. We administered docetaxel, cisplatin, and S-1 (DCS)therapy for unresectable gastric cancer. After 11 courses of DCS, we confirmed that the distant lymph node metasta- ses were significantly reduced. We performed radiotherapy(30 Gy/10 Fr)on the thoracic lumber vertebrae. Because the patient was successfully downstaged, we performed total gastrectomy with Roux-en-Y reconstruction...
October 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
(no author information available yet)
No abstract text is available yet for this article.
October 2018: Netherlands Journal of Medicine
K van Stapele, E C T Geijteman, T C van Thiel, P T E Postema, D H Schweitzer
No abstract text is available yet for this article.
October 2018: Netherlands Journal of Medicine
Tamas F Molnar
Knowledge on ontogenesis of thoracic surgery is essential not only for understanding present concepts and debates on surgery for tuberculosis, but it also contributes to the further developments in operative treatment of lung cancer. Both diseases have been the leading cause of death in their respective ages. History of tuberculosis follows the classic algorithm: diagnostic, casuistic and therapeutical stages. Villemin followed by Virchow, and, finally, Koch revealed the pathoanatomy and the cause of tuberculosis...
August 2018: Journal of Thoracic Disease
Bruno Mf Duarte, Rita R Pinheiro, Joana Cabete
Multiple miliary osteoma cutis consists of heterotopic foci of bone tissue in the dermis and subcutaneous tissue. Patients usually present with multiple, asymptomatic facial papules of several millimetres in diameter which cause distress regarding their cosmetic appearance. The condition is described as rare, as only a few cases have been reported since its first description in 1864 by Virchow. We therefore carried out a comprehensive literature search and review, in which 102 published cases were retrieved and analysed...
October 15, 2018: European Journal of Dermatology: EJD
Manoj Gopinath, Chinmay Nagesh, Chandrasekhar Kesavadas
No abstract text is available yet for this article.
July 2018: Indian Journal of Radiology & Imaging
Marek Lommatzsch, Maria Klein, Paul Stoll, Johann Christian Virchow
Here, we report that increasing treatment with inhaled corticosteroids (ICS) in patients with not well-controlled asthma from a medium to a high dose results in a profound reduction of blood eosinophils (median fall in blood eosinophil concentrations from 560 to 320 cells/µL). Therefore, 'normal values' of blood eosinophils in patients with asthma need to be considered in view of the individual ICS doses of the patients. In addition, increases in the dose of ICS may result in blood eosinophil concentrations which would formally preclude treatment with biologics targeting the interleukin-5 pathway...
October 12, 2018: Thorax
Emma Kate Zadow, Murray John Adams, Cecilia M Kitic, Sam Shi Xuan Wu, James William Fell
While athletes are often considered the epitome of health due to their physique and lowered potential for metabolic and cardiovascular diseases, they may also be at risk for the onset and development of venous thromboembolism (VTE). In an attempt to achieve and remain competitive, athletes are frequently exposed to numerous athlete-specific risk factors, which may predispose them to VTE through the disruption of factors associated with Virchow's triad (i.e., hypercoagulability, venous stasis, and vessel wall injury)...
November 2018: Seminars in Thrombosis and Hemostasis
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