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Leonello Tacconi, Roberto Spinelli, Francesco Signorelli
BACKGROUND: Traditional wound closure techniques include skin sutures and metal clips. Cyanoacrylate (2-Octyl-Cyanoacrylate "Dermabond C", by Ethicon, Germany) has good neovascularization, epithelialization and antimicrobial activity properties and a fast application procedure. This study presents our long-term experience. METHODS: We retrospectively selected 362 patients who underwent brain surgery from January 2007 to March 2017. Exclusion criteria was applied for repeat surgeries, emergency/post-traumatic procedures, wound infections, wounds longer than 16 centimeters, skull base cases, post-operative patients who stayed in the ICU more than 1 day...
October 15, 2018: World Neurosurgery
Siobhan Robinson, Christa C Christ, Margaret M Cahill, Sara J Aldrich, Elisa Taylor-Yeremeeva
Many people will experience at least one traumatic event in their lifetime, with up to 20% developing Post-Traumatic Stress Disorder (PTSD) or PTSD-like symptoms. In addition, the likelihood that females will develop PTSD after trauma is more than twice that of males. Despite its prevalence, current treatment strategies for trauma victims are limited and substantial portions of affected individuals remain resistant to treatment suggesting that additional interventions are necessary. Using an animal model of traumatic stress, the present studies tested the hypothesis that either voluntary exercise and/or administration of the adrenergic beta-receptor antagonist propranolol, would ameliorate stress-related maladaptive behaviors...
October 15, 2018: Physiology & Behavior
Ruby Mendenhall
Scholars are beginning to use the concept medicalization of poverty to theorize how the United States spends large amounts of money on illnesses related to poverty but invests much less in preventing these illnesses and the conditions that create them (e.g., economic insecurity, housing instability, continuous exposure to violence, and racism). This study examines the connection between poverty, disease burden and health-related costs through the in-depth interviews of 86 Black mothers living in neighborhoods with high levels of violence on the South Side of Chicago...
September 2018: Journal of Law, Medicine & Ethics: a Journal of the American Society of Law, Medicine & Ethics
Atsushi Takahashi, Tetsuya Ohira, Kanako Okazaki, Seiji Yasumura, Akira Sakai, Masaharu Maeda, Hirooki Yabe, Mitsuaki Hosoya, Akira Ohtsuru, Yukihiko Kawasaki, Hitoshi Suzuki, Michio Shimabukuro, Yoshihiro Sugiura, Hiroaki Shishido, Yoshimitsu Hayashi, Hironori Nakano, Gen Kobashi, Kenji Kamiya, Hiromasa Ohira
Dramatic lifestyle changes due to the Fukushima Daiichi Nuclear Power Plant accident increased the prevalence of hepatobiliary enzyme abnormalities (HEA). We aimed to evaluate associations of HEA with specific lifestyle- and disaster-related factors in residents who lived near the Fukushima Daiichi Nuclear Power Plant.This cross-sectional study included 22,246 residents who underwent a Comprehensive Health Check and the Mental Health and Lifestyle Survey from June 2011 to March 2012. Residents were divided into 2 groups based on residential area and housing status after the accident...
October 2018: Medicine (Baltimore)
Su Mi Park, Jung-Seok Choi, Ji Sun Lee, Jun-Young Lee, Saerom Lee, Hee Yeon Jung
This study aimed to examine the executive functioning of survivors exposed to recent sexual assaults. Twenty-seven female rape survivors who met the criterion for acute stress disorder (ASD) were enrolled and completed the assessment within 4 weeks after the traumatic experience. Additionally, 25 age-matched female health controls (HC) never exposed to such a traumatic event were enrolled. The assessments evaluated psychiatric symptoms including post-traumatic stress symptoms, depression, anxiety, and trait and state anger; general intelligence indexed by intellectual quotient (IQ); and executive functioning including set-shift/attention, planning, spatial working memory, and inhibition using the Cambridge Neuropsychological Test Automated Battery...
October 16, 2018: Journal of Clinical Medicine
A M V Gerlicher, O Tüscher, R Kalisch
Fear extinction does not prevent post-traumatic stress or have long-term therapeutic benefits in fear-related disorders unless extinction memories are easily retrieved at later encounters with the once-threatening stimulus. Previous research in rodents has pointed towards a role for spontaneous prefrontal activity occurring after extinction learning in stabilizing and consolidating extinction memories. In other memory domains spontaneous post-learning activity has been linked to dopamine. Here, we show that a neural activation pattern - evoked in the ventromedial prefrontal cortex (vmPFC) by the unexpected omission of the feared outcome during extinction learning - spontaneously reappears during postextinction rest...
October 16, 2018: Nature Communications
Michelle McIntyre, Carolyn Ehrlich, Elizabeth Kendall
PURPOSE: Much of the support required to live in the community post-traumatic brain injury (TBI) is provided by informal carers. Understanding the nature of caregiving work is important to better support informal carers. This study explored the work being performed by informal carers, and factors impacting on their capacity to manage the workload. METHOD: Participants comprised 21 dyads each consisting of an adult with moderate to severe TBI and a nominated carer...
October 16, 2018: Disability and Rehabilitation
Olinda Habib Perez, Robin E Green, George Mochizuki
PURPOSE: To identify impairments and recovery of balance control after moderate-severe traumatic brain injury (TBI) through spectral analyses of static balance tasks and to characterise the contributions of each limb to balance control. METHODS: A retrospective analysis of longitudinal balance data from force platforms at 2, 5, and 12 months post-injury in 31 individuals with moderate to severe TBI was performed. Single-visit data from age-matched controls (n = 22) were collected for descriptive comparison...
October 16, 2018: Disability and Rehabilitation
Rym Hamed, Amel Maaref, Feten Amira, Houssem Aouni, Imen Mekki, Amina Jebali
BACKGROUND: Severe Trauma is a misleading cause of death in young people. Early assessment of prognosis is the cornerstone in the management of such patients. Several prognostic scores have been proposed during the last decade. AIM: To evaluate the prognostic performance of trauma scores in terms of mortality in severe trauma patients admitted to the emergency department. METHODS: This was a prospective, observational and prognostic study with inclusion of severe trauma patients admitted to the emergency department over a 20 months period...
March 2018: La Tunisie Médicale
Ibrar Khan, Muhammad Asif Qureshi, Syed Husnain Abbas, Mahmood Shaukat
This is a retrospective study of seven patients with post-traumatic and iatrogenic urethrocutaneous fistula of penile urethra, excluding complication of hypospadias surgery. It was conducted in the Paediatric Surgery Department, Jinnah Hospital Lahore from June 2014 to January 2017. The patients ages ranged from three to twelve years. All the patients were managed by repairing the fistula in three layers electively at 3 months from the date of initial presentation. They remain well with no complaints except one with a recurrence...
June 2018: JPMA. the Journal of the Pakistan Medical Association
Marta Tremolada, Sabrina Bonichini, Giuseppe Basso, Marta Pillon
PURPOSE: Few studies have captured the unique ways in which cancer affects the growth and development of adolescent and young adult cancer survivors. This paper illustrates the daily life of childhood cancer survivors who are now adolescents and young adults, their post-traumatic growth and follow-up perceptions, adopting a narrative approach. METHODS: One thousand adolescent and young adult cancer survivors, mean age at diagnosis being 9.26 years old (SD = 4...
October 2018: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
David Jaffe, David Vier, Christian Royer
BACKGROUND: Avascular necrosis of the distal tibial plafond following ankle trauma is an underreported and potentially devastating phenomenon. Beyond conservative treatment options, surgical intervention has been limited to ankle arthrodesis, which sacrifices motion and may have longterm sequellae for adjacent hindfoot joints. Total ankle replacement has been historically contraindicated. Unipolar allograft reconstruction provides an option for joint salvage. We present a literature overview, implantation technique, and two cases utilizing matched unipolar distal tibial allograft...
April 22, 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Philip Peter Roessler, Rahel Bornemann, Cornelius Jacobs, Robert Pflugmacher, Matthias Trost, Stefanie Hölscher-Doht, Hendrik Jansen, Sönke Percy Frey
So far, there has been no clear explanation of the pathophysiological relationships in the development of HO. There is little experimental data dealing with the post-traumatic inflammatory response in terms of a balance between the repair of damaged muscle cells and the opposite response in its development. There are numerous indications regarding possible predisposing factors, such as existence of surrounding tissue hypoxia or the function of pro-angiogenic (VEGF e.g.) and osteoinductive (BMP e.g.) factors...
October 15, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
Zaĭniddin Norman Ugli, F Sh Bakhriddinov, O Kh Khusanov
Described in the article is the technique of temporary roentgenoendovascular balloon occlusion of major arteries during reconstructive and restorative operations in patients with post-traumatic arteriovenous fistulas and false aneurysms. Also presented are two clinical case reports demonstrating efficacy of preliminary temporary roentgenoendovascular occlusion of vessels in reconstructive operations on lower limb arteries for post-traumatic lesions thereof.
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
John M Clements, Stephanie J Rhynard
This study uses data from the 2012 National Inpatient Sample to determine if mortality, length of stay, and discharge disposition are different between rural and urban American Indians and Alaska Natives (AI/ANs) with alcohol abuse, depression, diabetes, and post-traumatic stress disorder. Results show no difference in mortality between groups. Alcohol abuse, depression, and diabetes are less prevalent in rural AI/ANs, and rural patients have shorter lengths of stay and fewer chronic conditions, diagnoses, and procedures...
2018: American Indian and Alaska Native Mental Health Research: the Journal of the National Center
Kirby Magid, Renée El-Gabalawy, Anbukarasi Maran, Eva R Serber
This study examined the association between post-traumatic growth (PTG), post-traumatic stress disorder (PTSD), and trauma-related factors in cardiac outpatients. Participants recruited from four cardiology clinics between November 2014 and July 2015 (N = 52, 69.2% men, Mage = 65 years) completed self-assessments of PTG and PTSD along with demographic, cardiac health index, and trauma-related factors. In total, 75% of the sample endorsed their cardiac event as traumatic, while 17.2% reported their cardiac event as their 'worst trauma'; those endorsing the latter did not significantly differ from those endorsing 'other traumas' as their worst...
October 13, 2018: Journal of Clinical Psychology in Medical Settings
Helen Spiby, Kayleigh Sheen, Sarah Collinge, Clare Maxwell, Kerry Pollard, Pauline Slade
BACKGROUND: Midwifery students can experience events on clinical placements that they perceive to be traumatic. There is currently no requirement to provide training about the nature of trauma, normal responses, or the most helpful ways of self-managing these. The POPPY programme, developed for qualified midwives, incorporates educational (the POPPY workshop) and supportive resources to prevent the development of Post-Traumatic Stress Disorder in midwives. As part of the feasibility evaluation of POPPY, the POPPY workshop element was adapted for pre-registration midwifery students (PreR-POPPY)...
September 29, 2018: Nurse Education Today
Peng-Fei Han, Lei Wei, Zhi-Qing Duan, Zhi-Liang Zhang, Tao-Yu Chen, Jian-Gong Lu, Rui-Peng Zhao, Xiao-Ming Cao, Peng-Cui Li, Zhi Lv, Xiao-Chun Wei
BACKGROUND: It has been noted that anterior cruciate ligament (ACL) injury-induced cartilage degeneration is the key risk factor for post-traumatic osteoarthritis (PTOA). However, whether the cartilage degeneration after ACL injury is caused by inflammation, abnormal biomechanics or both remains largely unknown, as there has been no animal model for separating the two factors so far. METHODS: Eighteen-month-old female mini-pigs were divided into an "idealized" anterior cruciate ligament reconstruction (IACLR) group and a control group (n = 16 limbs per group)...
October 11, 2018: International Immunopharmacology
Sharon R Lewis, Michael W Pritchard, Oliver J Schofield-Robinson, David Jw Evans, Phil Alderson, Andrew F Smith
BACKGROUND: During intensive care unit (ICU) admission, patients and their carers experience physical and psychological stressors that may result in psychological conditions including anxiety, depression, and post-traumatic stress disorder (PTSD). Improving communication between healthcare professionals, patients, and their carers may alleviate these disorders. Communication may include information or educational interventions, in different formats, aiming to improve knowledge of the prognosis, treatment, or anticipated challenges after ICU discharge...
October 13, 2018: Cochrane Database of Systematic Reviews
Karem H Alzoubi, Alaa M Al-Ibbini, Khawla Q Nuseir
Post-traumatic stress disorder (PTSD) may occur after exposure to stressful, fearful or troubling events. Until now, there is no curable medication for this disorder. Cerebrolysin is a neuropeptide, which has an important role in the treatment of vascular dementia. In this study, the probable protective effect of cerebrolysin on PTSD-induced memory impairment was investigated. To induce PTSD, the single prolonged stress (SPS) model was used. Rats were allocated into four groups: control (vehicle-treated), CBL (administrated cerebrolysin 2...
October 6, 2018: Psychiatry Research
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