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https://www.readbyqxmd.com/read/30517966/ubtf-mutation-causes-complex-phenotype-of-neurodegeneration-and-severe-epilepsy-in-childhood
#1
Lucie Sedláčková, Petra Laššuthová, Katalin Štěrbová, Jana Haberlová, Emílie Vyhnálková, Jana Neupauerová, David Staněk, Marie Šedivá, Pavel Kršek, Pavel Seeman
INTRODUCTION:  Neurodegenerative diseases of childhood present with progressive decline in cognitive, social, and motor function and are frequently associated with seizures in different stages of the disease. Here we report a patient with severe progressive neurodegeneration with drug-resistant epilepsy of unknown etiology from the age of 2 years. METHODS AND RESULTS:  Using whole exome sequencing, we found heterozygous missense de novo variant c.628G > A (p...
December 5, 2018: Neuropediatrics
https://www.readbyqxmd.com/read/30517841/mass-spectrometric-imaging-of-cysteine-rich-proteins-in-human-skin
#2
Lucie Vanickova, Roman Guran, Sándor Kollár, Gabriella Emri, Sona Krizkova, Tomas Do, Zbynek Heger, Ondrej Zitka, Vojtech Adam
Looking insight pathological processes, metallothioneins (MTs) are considered to be potential biomarkers for monitoring of a development of various types of malignant disease, such as cancer. The early identification of the MT biomarkers in biological tissues could be important tool for the estimation of appropriate clinical therapy. Therefore here we investigated the application of matrix assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) together with immunohistochemical analyses (IHC) using MT-1/2 antibody for MT detection in formalin-fixed paraffin-embedded (FFPE) biopsy specimens of human skin...
December 2, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/30517824/multilevel-factors-influencing-young-mothers-breastfeeding-a-qualitative-cbpr-study
#3
Alison Chopel, Danielle Soto, Bre'Jaynae Joiner, Tina Benitez, Ruth Konoff, Lucy Rios, Elva Castellanos
BACKGROUND: Young mothers (age 14-24 years), who are often low income, are less likely than other mothers to breastfeed for 6 months. They also are more likely to be diagnosed with aggressive forms of breast cancer; breastfeeding significantly reduces this risk. While adolescent breastfeeding has been investigated from the perspective of the individual, the social ecological model recognizes the influence of factors at multiple levels. RESEARCH AIM: The aim was to identify social and structural barriers to and motivators of breastfeeding that young mothers may encounter...
December 5, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/30517796/combination-of-the-searches-for-pair-produced-vectorlike-partners-of-the-third-generation-quarks-at-sqrt-s-13-tev-with-the-atlas-detector
#4
M Aaboud, G Aad, B Abbott, O Abdinov, B Abeloos, D K Abhayasinghe, S H Abidi, O S AbouZeid, N L Abraham, H Abramowicz, H Abreu, Y Abulaiti, B S Acharya, S Adachi, L Adam, L Adamczyk, J Adelman, M Adersberger, A Adiguzel, T Adye, A A Affolder, Y Afik, C Agheorghiesei, J A Aguilar-Saavedra, F Ahmadov, G Aielli, S Akatsuka, T P A Åkesson, E Akilli, A V Akimov, G L Alberghi, J Albert, P Albicocco, M J Alconada Verzini, S Alderweireldt, M Aleksa, I N Aleksandrov, C Alexa, T Alexopoulos, M Alhroob, B Ali, G Alimonti, J Alison, S P Alkire, C Allaire, B M M Allbrooke, B W Allen, P P Allport, A Aloisio, A Alonso, F Alonso, C Alpigiani, A A Alshehri, M I Alstaty, B Alvarez Gonzalez, D Álvarez Piqueras, M G Alviggi, B T Amadio, Y Amaral Coutinho, A Ambler, L Ambroz, C Amelung, D Amidei, S P Amor Dos Santos, S Amoroso, C S Amrouche, C Anastopoulos, L S Ancu, N Andari, T Andeen, C F Anders, J K Anders, K J Anderson, A Andreazza, V Andrei, C R Anelli, S Angelidakis, I Angelozzi, A Angerami, A V Anisenkov, A Annovi, C Antel, M T Anthony, M Antonelli, D J A Antrim, F Anulli, M Aoki, J A Aparisi Pozo, L Aperio Bella, G Arabidze, J P Araque, V Araujo Ferraz, R Araujo Pereira, A T H Arce, R E Ardell, F A Arduh, J-F Arguin, S Argyropoulos, A J Armbruster, L J Armitage, A Armstrong, O Arnaez, H Arnold, M Arratia, O Arslan, A Artamonov, G Artoni, S Artz, S Asai, N Asbah, E M Asimakopoulou, L Asquith, K Assamagan, R Astalos, R J Atkin, M Atkinson, N B Atlay, K Augsten, G Avolio, R Avramidou, M K Ayoub, A M Azoulay, G Azuelos, A E Baas, M J Baca, H Bachacou, K Bachas, M Backes, P Bagnaia, M Bahmani, H Bahrasemani, A J Bailey, J T Baines, M Bajic, C Bakalis, O K Baker, P J Bakker, D Bakshi Gupta, S Balaji, E M Baldin, P Balek, F Balli, W K Balunas, J Balz, E Banas, A Bandyopadhyay, S Banerjee, A A E Bannoura, L Barak, W M Barbe, E L Barberio, D Barberis, M Barbero, T Barillari, M-S Barisits, J Barkeloo, T Barklow, R Barnea, S L Barnes, B M Barnett, R M Barnett, Z Barnovska-Blenessy, A Baroncelli, G Barone, A J Barr, L Barranco Navarro, F Barreiro, J Barreiro Guimarães da Costa, R Bartoldus, A E Barton, P Bartos, A Basalaev, A Bassalat, R L Bates, S J Batista, S Batlamous, J R Batley, M Battaglia, M Bauce, F Bauer, K T Bauer, H S Bawa, J B Beacham, T Beau, P H Beauchemin, P Bechtle, H C Beck, H P Beck, K Becker, M Becker, C Becot, A Beddall, A J Beddall, V A Bednyakov, M Bedognetti, C P Bee, T A Beermann, M Begalli, M Begel, A Behera, J K Behr, A S Bell, G Bella, L Bellagamba, A Bellerive, M Bellomo, P Bellos, K Belotskiy, N L Belyaev, O Benary, D Benchekroun, M Bender, N Benekos, Y Benhammou, E Benhar Noccioli, J Benitez, D P Benjamin, M Benoit, J R Bensinger, S Bentvelsen, L Beresford, M Beretta, D Berge, E Bergeaas Kuutmann, N Berger, L J Bergsten, J Beringer, S Berlendis, N R Bernard, G Bernardi, C Bernius, F U Bernlochner, T Berry, P Berta, C Bertella, G Bertoli, I A Bertram, G J Besjes, O Bessidskaia Bylund, M Bessner, N Besson, A Bethani, S Bethke, A Betti, A J Bevan, J Beyer, R Bi, R M B Bianchi, O Biebel, D Biedermann, R Bielski, K Bierwagen, N V Biesuz, M Biglietti, T R V Billoud, M Bindi, A Bingul, C Bini, S Biondi, M Birman, T Bisanz, J P Biswal, C Bittrich, D M Bjergaard, J E Black, K M Black, T Blazek, I Bloch, C Blocker, A Blue, U Blumenschein, Dr Blunier, G J Bobbink, V S Bobrovnikov, S S Bocchetta, A Bocci, D Boerner, D Bogavac, A G Bogdanchikov, C Bohm, V Boisvert, P Bokan, T Bold, A S Boldyrev, A E Bolz, M Bomben, M Bona, J S Bonilla, M Boonekamp, A Borisov, G Borissov, J Bortfeldt, D Bortoletto, V Bortolotto, D Boscherini, M Bosman, J D Bossio Sola, K Bouaouda, J Boudreau, E V Bouhova-Thacker, D Boumediene, C Bourdarios, S K Boutle, A Boveia, J Boyd, D Boye, I R Boyko, A J Bozson, J Bracinik, N Brahimi, A Brandt, G Brandt, O Brandt, F Braren, U Bratzler, B Brau, J E Brau, W D Breaden Madden, K Brendlinger, L Brenner, R Brenner, S Bressler, B Brickwedde, D L Briglin, D Britton, D Britzger, I Brock, R Brock, G Brooijmans, T Brooks, W K Brooks, E Brost, J H Broughton, P A Bruckman de Renstrom, D Bruncko, A Bruni, G Bruni, L S Bruni, S Bruno, B H Brunt, M Bruschi, N Bruscino, P Bryant, L Bryngemark, T Buanes, Q Buat, P Buchholz, A G Buckley, I A Budagov, F Buehrer, M K Bugge, O Bulekov, D Bullock, T J Burch, S Burdin, C D Burgard, A M Burger, B Burghgrave, K Burka, S Burke, I Burmeister, J T P Burr, V Büscher, E Buschmann, P Bussey, J M Butler, C M Buttar, J M Butterworth, P Butti, W Buttinger, A Buzatu, A R Buzykaev, G Cabras, S Cabrera Urbán, D Caforio, H Cai, V M M Cairo, O Cakir, N Calace, P Calafiura, A Calandri, G Calderini, P Calfayan, G Callea, L P Caloba, S Calvente Lopez, D Calvet, S Calvet, T P Calvet, M Calvetti, R Camacho Toro, S Camarda, P Camarri, D Cameron, R Caminal Armadans, C Camincher, S Campana, M Campanelli, A Camplani, A Campoverde, V Canale, M Cano Bret, J Cantero, T Cao, Y Cao, M D M Capeans Garrido, I Caprini, M Caprini, M Capua, R M Carbone, R Cardarelli, F C Cardillo, I Carli, T Carli, G Carlino, B T Carlson, L Carminati, R M D Carney, S Caron, E Carquin, S Carrá, G D Carrillo-Montoya, D Casadei, M P Casado, A F Casha, D W Casper, R Castelijn, F L Castillo, V Castillo Gimenez, N F Castro, A Catinaccio, J R Catmore, A Cattai, J Caudron, V Cavaliere, E Cavallaro, D Cavalli, M Cavalli-Sforza, V Cavasinni, E Celebi, F Ceradini, L Cerda Alberich, A S Cerqueira, A Cerri, L Cerrito, F Cerutti, A Cervelli, S A Cetin, A Chafaq, D Chakraborty, S K Chan, W S Chan, Y L Chan, J D Chapman, B Chargeishvili, D G Charlton, C C Chau, C A Chavez Barajas, S Che, A Chegwidden, S Chekanov, S V Chekulaev, G A Chelkov, M A Chelstowska, C Chen, C H Chen, H Chen, J Chen, J Chen, S Chen, S J Chen, X Chen, Y Chen, Y-H Chen, H C Cheng, H J Cheng, A Cheplakov, E Cheremushkina, R Cherkaoui El Moursli, E Cheu, K Cheung, L Chevalier, V Chiarella, G Chiarelli, G Chiodini, A S Chisholm, A Chitan, I Chiu, Y H Chiu, M V Chizhov, K Choi, A R Chomont, S Chouridou, Y S Chow, V Christodoulou, M C Chu, J Chudoba, A J Chuinard, J J Chwastowski, L Chytka, D Cinca, V Cindro, I A Cioară, A Ciocio, F Cirotto, Z H Citron, M Citterio, A Clark, M R Clark, P J Clark, C Clement, Y Coadou, M Cobal, A Coccaro, J Cochran, H Cohen, A E C Coimbra, L Colasurdo, B Cole, A P Colijn, J Collot, P Conde Muiño, E Coniavitis, S H Connell, I A Connelly, S Constantinescu, F Conventi, A M Cooper-Sarkar, F Cormier, K J R Cormier, L D Corpe, M Corradi, E E Corrigan, F Corriveau, A Cortes-Gonzalez, M J Costa, F Costanza, D Costanzo, G Cottin, G Cowan, B E Cox, J Crane, K Cranmer, S J Crawley, R A Creager, G Cree, S Crépé-Renaudin, F Crescioli, M Cristinziani, V Croft, G Crosetti, A Cueto, T Cuhadar Donszelmann, A R Cukierman, S Czekierda, P Czodrowski, M J Da Cunha Sargedas De Sousa, C Da Via, W Dabrowski, T Dado, S Dahbi, T Dai, F Dallaire, C Dallapiccola, M Dam, G D'amen, J Damp, J R Dandoy, M F Daneri, N P Dang, N D Dann, M Danninger, V Dao, G Darbo, S Darmora, O Dartsi, A Dattagupta, T Daubney, S D'Auria, W Davey, C David, T Davidek, D R Davis, E Dawe, I Dawson, K De, R De Asmundis, A De Benedetti, M De Beurs, S De Castro, S De Cecco, N De Groot, P de Jong, H De la Torre, F De Lorenzi, A De Maria, D De Pedis, A De Salvo, U De Sanctis, M De Santis, A De Santo, K De Vasconcelos Corga, J B De Vivie De Regie, C Debenedetti, D V Dedovich, N Dehghanian, M Del Gaudio, J Del Peso, Y Delabat Diaz, D Delgove, F Deliot, C M Delitzsch, M Della Pietra, D Della Volpe, A Dell'Acqua, L Dell'Asta, M Delmastro, C Delporte, P A Delsart, D A DeMarco, S Demers, M Demichev, S P Denisov, D Denysiuk, L D'Eramo, D Derendarz, J E Derkaoui, F Derue, P Dervan, K Desch, C Deterre, K Dette, M R Devesa, P O Deviveiros, A Dewhurst, S Dhaliwal, F A Di Bello, A Di Ciaccio, L Di Ciaccio, W K Di Clemente, C Di Donato, A Di Girolamo, G Di Gregorio, B Di Micco, R Di Nardo, K F Di Petrillo, R Di Sipio, D Di Valentino, C Diaconu, M Diamond, F A Dias, T Dias Do Vale, M A Diaz, J Dickinson, E B Diehl, J Dietrich, S Díez Cornell, A Dimitrievska, J Dingfelder, F Dittus, F Djama, T Djobava, J I Djuvsland, M A B Do Vale, M Dobre, D Dodsworth, C Doglioni, J Dolejsi, Z Dolezal, M Donadelli, J Donini, A D'onofrio, M D'Onofrio, J Dopke, A Doria, M T Dova, A T Doyle, E Drechsler, E Dreyer, T Dreyer, Y Du, F Dubinin, M Dubovsky, A Dubreuil, E Duchovni, G Duckeck, A Ducourthial, O A Ducu, D Duda, A Dudarev, A C Dudder, E M Duffield, L Duflot, M Dührssen, C Dülsen, M Dumancic, A E Dumitriu, A K Duncan, M Dunford, A Duperrin, H Duran Yildiz, M Düren, A Durglishvili, D Duschinger, B Dutta, D Duvnjak, M Dyndal, S Dysch, B S Dziedzic, C Eckardt, K M Ecker, R C Edgar, T Eifert, G Eigen, K Einsweiler, T Ekelof, M El Kacimi, R El Kosseifi, V Ellajosyula, M Ellert, F Ellinghaus, A A Elliot, N Ellis, J Elmsheuser, M Elsing, D Emeliyanov, A Emerman, Y Enari, J S Ennis, M B Epland, J Erdmann, A Ereditato, S Errede, M Escalier, C Escobar, O Estrada Pastor, A I Etienvre, E Etzion, H Evans, A Ezhilov, M Ezzi, F Fabbri, L Fabbri, V Fabiani, G Facini, R M Faisca Rodrigues Pereira, R M Fakhrutdinov, S Falciano, P J Falke, S Falke, J Faltova, Y Fang, M Fanti, A Farbin, A Farilla, E M Farina, T Farooque, S Farrell, S M Farrington, P Farthouat, F Fassi, P Fassnacht, D Fassouliotis, M Faucci Giannelli, A Favareto, W J Fawcett, L Fayard, O L Fedin, W Fedorko, M Feickert, S Feigl, L Feligioni, C Feng, E J Feng, M Feng, M J Fenton, A B Fenyuk, L Feremenga, J Ferrando, A Ferrari, P Ferrari, R Ferrari, D E Ferreira de Lima, A Ferrer, D Ferrere, C Ferretti, F Fiedler, A Filipčič, F Filthaut, K D Finelli, M C N Fiolhais, L Fiorini, C Fischer, W C Fisher, N Flaschel, I Fleck, P Fleischmann, R R M Fletcher, T Flick, B M Flierl, L M Flores, L R Flores Castillo, F M Follega, N Fomin, G T Forcolin, A Formica, F A Förster, A C Forti, A G Foster, D Fournier, H Fox, S Fracchia, P Francavilla, M Franchini, S Franchino, D Francis, L Franconi, M Franklin, M Frate, M Fraternali, A N Fray, D Freeborn, S M Fressard-Batraneanu, B Freund, W S Freund, E M Freundlich, D C Frizzell, D Froidevaux, J A Frost, C Fukunaga, E Fullana Torregrosa, T Fusayasu, J Fuster, O Gabizon, A Gabrielli, A Gabrielli, G P Gach, S Gadatsch, P Gadow, G Gagliardi, L G Gagnon, C Galea, B Galhardo, E J Gallas, B J Gallop, P Gallus, G Galster, R Gamboa Goni, K K Gan, S Ganguly, J Gao, Y Gao, Y S Gao, C García, J E García Navarro, J A García Pascual, M Garcia-Sciveres, R W Gardner, N Garelli, V Garonne, K Gasnikova, A Gaudiello, G Gaudio, I L Gavrilenko, A Gavrilyuk, C Gay, G Gaycken, E N Gazis, C N P Gee, J Geisen, M Geisen, M P Geisler, K Gellerstedt, C Gemme, M H Genest, C Geng, S Gentile, S George, D Gerbaudo, G Gessner, S Ghasemi, M Ghasemi Bostanabad, M Ghneimat, B Giacobbe, S Giagu, N Giangiacomi, P Giannetti, A Giannini, S M Gibson, M Gignac, D Gillberg, G Gilles, D M Gingrich, M P Giordani, F M Giorgi, P F Giraud, P Giromini, G Giugliarelli, D Giugni, F Giuli, M Giulini, S Gkaitatzis, I Gkialas, E L Gkougkousis, P Gkountoumis, L K Gladilin, C Glasman, J Glatzer, P C F Glaysher, A Glazov, M Goblirsch-Kolb, J Godlewski, S Goldfarb, T Golling, D Golubkov, A Gomes, R Goncalves Gama, R Gonçalo, G Gonella, L Gonella, A Gongadze, F Gonnella, J L Gonski, S González de la Hoz, S Gonzalez-Sevilla, L Goossens, P A Gorbounov, H A Gordon, B Gorini, E Gorini, A Gorišek, A T Goshaw, C Gössling, M I Gostkin, C A Gottardo, C R Goudet, D Goujdami, A G Goussiou, N Govender, C Goy, E Gozani, I Grabowska-Bold, P O J Gradin, E C Graham, J Gramling, E Gramstad, S Grancagnolo, V Gratchev, P M Gravila, F G Gravili, C Gray, H M Gray, Z D Greenwood, C Grefe, K Gregersen, I M Gregor, P Grenier, K Grevtsov, N A Grieser, J Griffiths, A A Grillo, K Grimm, S Grinstein, Ph Gris, J-F Grivaz, S Groh, E Gross, J Grosse-Knetter, G C Grossi, Z J Grout, C Grud, A Grummer, L Guan, W Guan, J Guenther, A Guerguichon, F Guescini, D Guest, R Gugel, B Gui, T Guillemin, S Guindon, U Gul, C Gumpert, J Guo, W Guo, Y Guo, Z Guo, R Gupta, S Gurbuz, G Gustavino, B J Gutelman, P Gutierrez, C Gutschow, C Guyot, M P Guzik, C Gwenlan, C B Gwilliam, A Haas, C Haber, H K Hadavand, N Haddad, A Hadef, S Hageböck, M Hagihara, H Hakobyan, M Haleem, J Haley, G Halladjian, G D Hallewell, K Hamacher, P Hamal, K Hamano, A Hamilton, G N Hamity, K Han, L Han, S Han, K Hanagaki, M Hance, D M Handl, B Haney, R Hankache, P Hanke, E Hansen, J B Hansen, J D Hansen, M C Hansen, P H Hansen, K Hara, A S Hard, T Harenberg, S Harkusha, P F Harrison, N M Hartmann, Y Hasegawa, A Hasib, S Hassani, S Haug, R Hauser, L Hauswald, L B Havener, M Havranek, C M Hawkes, R J Hawkings, D Hayden, C Hayes, C P Hays, J M Hays, H S Hayward, S J Haywood, M P Heath, V Hedberg, L Heelan, S Heer, K K Heidegger, J Heilman, S Heim, T Heim, B Heinemann, J J Heinrich, L Heinrich, C Heinz, J Hejbal, L Helary, A Held, S Hellesund, S Hellman, C Helsens, R C W Henderson, Y Heng, S Henkelmann, A M Henriques Correia, G H Herbert, H Herde, V Herget, Y Hernández Jiménez, H Herr, M G Herrmann, T Herrmann, G Herten, R Hertenberger, L Hervas, T C Herwig, G G Hesketh, N P Hessey, S Higashino, E Higón-Rodriguez, K Hildebrand, E Hill, J C Hill, K K Hill, K H Hiller, S J Hillier, M Hils, I Hinchliffe, M Hirose, D Hirschbuehl, B Hiti, O Hladik, D R Hlaluku, X Hoad, J Hobbs, N Hod, M C Hodgkinson, A Hoecker, M R Hoeferkamp, F Hoenig, D Hohn, D Hohov, T R Holmes, M Holzbock, M Homann, S Honda, T Honda, T M Hong, A Hönle, B H Hooberman, W H Hopkins, Y Horii, P Horn, A J Horton, L A Horyn, J-Y Hostachy, A Hostiuc, S Hou, A Hoummada, J Howarth, J Hoya, M Hrabovsky, I Hristova, J Hrivnac, A Hrynevich, T Hryn'ova, P J Hsu, S-C Hsu, Q Hu, S Hu, Y Huang, Z Hubacek, F Hubaut, M Huebner, F Huegging, T B Huffman, M Huhtinen, R F H Hunter, P Huo, A M Hupe, N Huseynov, J Huston, J Huth, R Hyneman, G Iacobucci, G Iakovidis, I Ibragimov, L Iconomidou-Fayard, Z Idrissi, P Iengo, R Ignazzi, O Igonkina, R Iguchi, T Iizawa, Y Ikegami, M Ikeno, D Iliadis, N Ilic, F Iltzsche, G Introzzi, M Iodice, K Iordanidou, V Ippolito, M F Isacson, N Ishijima, M Ishino, M Ishitsuka, W Islam, C Issever, S Istin, F Ito, J M Iturbe Ponce, R Iuppa, A Ivina, H Iwasaki, J M Izen, V Izzo, P Jacka, P Jackson, R M Jacobs, V Jain, G Jäkel, K B Jakobi, K Jakobs, S Jakobsen, T Jakoubek, D O Jamin, R Jansky, J Janssen, M Janus, P A Janus, G Jarlskog, N Javadov, T Javůrek, M Javurkova, F Jeanneau, L Jeanty, J Jejelava, A Jelinskas, P Jenni, J Jeong, N Jeong, S Jézéquel, H Ji, J Jia, H Jiang, Y Jiang, Z Jiang, S Jiggins, F A Jimenez Morales, J Jimenez Pena, S Jin, A Jinaru, O Jinnouchi, H Jivan, P Johansson, K A Johns, C A Johnson, W J Johnson, K Jon-And, R W L Jones, S D Jones, S Jones, T J Jones, J Jongmanns, P M Jorge, J Jovicevic, X Ju, J J Junggeburth, A Juste Rozas, A Kaczmarska, M Kado, H Kagan, M Kagan, T Kaji, E Kajomovitz, C W Kalderon, A Kaluza, S Kama, A Kamenshchikov, L Kanjir, Y Kano, V A Kantserov, J Kanzaki, B Kaplan, L S Kaplan, D Kar, M J Kareem, E Karentzos, S N Karpov, Z M Karpova, V Kartvelishvili, A N Karyukhin, L Kashif, R D Kass, A Kastanas, Y Kataoka, C Kato, J Katzy, K Kawade, K Kawagoe, T Kawamoto, G Kawamura, E F Kay, V F Kazanin, R Keeler, R Kehoe, J S Keller, E Kellermann, J J Kempster, J Kendrick, O Kepka, S Kersten, B P Kerševan, S Ketabchi Haghighat, R A Keyes, M Khader, F Khalil-Zada, A Khanov, A G Kharlamov, T Kharlamova, E E Khoda, A Khodinov, T J Khoo, E Khramov, J Khubua, S Kido, M Kiehn, C R Kilby, Y K Kim, N Kimura, O M Kind, B T King, D Kirchmeier, J Kirk, A E Kiryunin, T Kishimoto, D Kisielewska, V Kitali, O Kivernyk, E Kladiva, T Klapdor-Kleingrothaus, M H Klein, M Klein, U Klein, K Kleinknecht, P Klimek, A Klimentov, T Klingl, T Klioutchnikova, F F Klitzner, P Kluit, S Kluth, E Kneringer, E B F G Knoops, A Knue, A Kobayashi, D Kobayashi, T Kobayashi, M Kobel, M Kocian, P Kodys, P T Koenig, T Koffas, E Koffeman, N M Köhler, T Koi, M Kolb, I Koletsou, T Kondo, N Kondrashova, K Köneke, A C König, T Kono, R Konoplich, V Konstantinides, N Konstantinidis, B Konya, R Kopeliansky, S Koperny, K Korcyl, K Kordas, G Koren, A Korn, I Korolkov, E V Korolkova, N Korotkova, O Kortner, S Kortner, T Kosek, V V Kostyukhin, A Kotwal, A Koulouris, A Kourkoumeli-Charalampidi, C Kourkoumelis, E Kourlitis, V Kouskoura, A B Kowalewska, R Kowalewski, T Z Kowalski, C Kozakai, W Kozanecki, A S Kozhin, V A Kramarenko, G Kramberger, D Krasnopevtsev, M W Krasny, A Krasznahorkay, D Krauss, J A Kremer, J Kretzschmar, P Krieger, K Krizka, K Kroeninger, H Kroha, J Kroll, J Kroll, J Krstic, U Kruchonak, H Krüger, N Krumnack, M C Kruse, T Kubota, S Kuday, J T Kuechler, S Kuehn, A Kugel, F Kuger, T Kuhl, V Kukhtin, R Kukla, Y Kulchitsky, S Kuleshov, Y P Kulinich, M Kuna, T Kunigo, A Kupco, T Kupfer, O Kuprash, H Kurashige, L L Kurchaninov, Y A Kurochkin, A Kurova, M G Kurth, E S Kuwertz, M Kuze, J Kvita, T Kwan, A La Rosa, J L La Rosa Navarro, L La Rotonda, F La Ruffa, C Lacasta, F Lacava, J Lacey, D P J Lack, H Lacker, D Lacour, E Ladygin, R Lafaye, 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Zemaityte, J C Zeng, Q Zeng, O Zenin, D Zerwas, M Zgubič, D F Zhang, D Zhang, F Zhang, G Zhang, G Zhang, H Zhang, J Zhang, L Zhang, L Zhang, M Zhang, P Zhang, R Zhang, R Zhang, X Zhang, Y Zhang, Z Zhang, Y Zhao, Z Zhao, A Zhemchugov, Z Zheng, D Zhong, B Zhou, C Zhou, L Zhou, M S Zhou, M Zhou, N Zhou, Y Zhou, C G Zhu, H L Zhu, H Zhu, J Zhu, Y Zhu, X Zhuang, K Zhukov, V Zhulanov, A Zibell, D Zieminska, N I Zimine, S Zimmermann, Z Zinonos, M Zinser, M Ziolkowski, G Zobernig, A Zoccoli, K Zoch, T G Zorbas, R Zou, M Zur Nedden, L Zwalinski
A combination of the searches for pair-produced vectorlike partners of the top and bottom quarks in various decay channels (T→Zt/Wb/Ht, B→Zb/Wt/Hb) is performed using 36.1  fb^{-1} of pp collision data at sqrt[s]=13  TeV with the ATLAS detector at the Large Hadron Collider. The observed data are found to be in good agreement with the standard model background prediction in all individual searches. Therefore, combined 95% confidence-level upper limits are set on the production cross section for a range of vectorlike quark scenarios, significantly improving upon the reach of the individual searches...
November 23, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/30517793/observation-of-centrality-dependent-acoplanarity-for-muon-pairs-produced-via-two-photon-scattering-in-pb-pb-collisions-at-sqrt-s_-nn-5-02-tev-with-the-atlas-detector
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K O H Vadla, A Vaidya, C Valderanis, E Valdes Santurio, M Valente, S Valentinetti, A Valero, L Valéry, R A Vallance, A Vallier, J A Valls Ferrer, T R Van Daalen, W Van Den Wollenberg, H Van der Graaf, P Van Gemmeren, J Van Nieuwkoop, I Van Vulpen, M Vanadia, W Vandelli, A Vaniachine, P Vankov, R Vari, E W Varnes, C Varni, T Varol, D Varouchas, K E Varvell, G A Vasquez, J G Vasquez, F Vazeille, D Vazquez Furelos, T Vazquez Schroeder, J Veatch, V Vecchio, L M Veloce, F Veloso, S Veneziano, A Ventura, M Venturi, N Venturi, V Vercesi, M Verducci, C M Vergel Infante, W Verkerke, A T Vermeulen, J C Vermeulen, M C Vetterli, N Viaux Maira, M Vicente Barreto Pinto, I Vichou, T Vickey, O E Vickey Boeriu, G H A Viehhauser, S Viel, L Vigani, M Villa, M Villaplana Perez, E Vilucchi, M G Vincter, V B Vinogradov, A Vishwakarma, C Vittori, I Vivarelli, S Vlachos, M Vogel, P Vokac, G Volpi, S E von Buddenbrock, E Von Toerne, V Vorobel, K Vorobev, M Vos, J H Vossebeld, N Vranjes, M Vranjes Milosavljevic, V Vrba, M Vreeswijk, T Šfiligoj, R Vuillermet, I Vukotic, T Ženiš, L Živković, P Wagner, W Wagner, J Wagner-Kuhr, H Wahlberg, S Wahrmund, K Wakamiya, V M Walbrecht, J Walder, R Walker, S D Walker, W Walkowiak, V Wallangen, A M Wang, C Wang, F Wang, H Wang, H Wang, J Wang, J Wang, P Wang, Q Wang, R-J Wang, R Wang, R Wang, S M Wang, W T Wang, W Wang, W X Wang, Y Wang, Z Wang, C Wanotayaroj, A Warburton, C P Ward, D R Wardrope, A Washbrook, P M Watkins, A T Watson, M F Watson, G Watts, S Watts, B M Waugh, A F Webb, S Webb, C Weber, M S Weber, S A Weber, S M Weber, A R Weidberg, B Weinert, J Weingarten, M Weirich, C Weiser, P S Wells, T Wenaus, T Wengler, S Wenig, N Wermes, M D Werner, P Werner, M Wessels, T D Weston, K Whalen, N L Whallon, A M Wharton, A S White, A White, M J White, R White, D Whiteson, B W Whitmore, F J Wickens, W Wiedenmann, M Wielers, C Wiglesworth, L A M Wiik-Fuchs, A Wildauer, F Wilk, H G Wilkens, L J Wilkins, H H Williams, S Williams, C Willis, S Willocq, J A Wilson, I Wingerter-Seez, E Winkels, F Winklmeier, O J Winston, B T Winter, M Wittgen, M Wobisch, A Wolf, T M H Wolf, R Wolff, M W Wolter, H Wolters, V W S Wong, N L Woods, S D Worm, B K Wosiek, K W Woźniak, K Wraight, M Wu, S L Wu, X Wu, Y Wu, T R Wyatt, B M Wynne, S Xella, Z Xi, L Xia, D Xu, H Xu, L Xu, T Xu, W Xu, B Yabsley, S Yacoob, K Yajima, D P Yallup, D Yamaguchi, Y Yamaguchi, A Yamamoto, T Yamanaka, F Yamane, M Yamatani, T Yamazaki, Y Yamazaki, Z Yan, H J Yang, H T Yang, S Yang, Y Yang, Z Yang, W-M Yao, Y C Yap, Y Yasu, E Yatsenko, J Ye, S Ye, I Yeletskikh, E Yigitbasi, E Yildirim, K Yorita, K Yoshihara, C J S Young, C Young, J Yu, J Yu, X Yue, S P Y Yuen, B Zabinski, G Zacharis, E Zaffaroni, R Zaidan, A M Zaitsev, T Zakareishvili, N Zakharchuk, J Zalieckas, S Zambito, D Zanzi, D R Zaripovas, S V Zeißner, C Zeitnitz, G Zemaityte, J C Zeng, Q Zeng, O Zenin, D Zerwas, M Zgubič, D F Zhang, D Zhang, F Zhang, G Zhang, H Zhang, J Zhang, L Zhang, L Zhang, M Zhang, P Zhang, R Zhang, R Zhang, X Zhang, Y Zhang, Z Zhang, P Zhao, X Zhao, Y Zhao, Z Zhao, A Zhemchugov, B Zhou, C Zhou, L Zhou, M S Zhou, M Zhou, N Zhou, Y Zhou, C G Zhu, H L Zhu, H Zhu, J Zhu, Y Zhu, X Zhuang, K Zhukov, V Zhulanov, A Zibell, D Zieminska, N I Zimine, S Zimmermann, Z Zinonos, M Zinser, M Ziolkowski, G Zobernig, A Zoccoli, K Zoch, T G Zorbas, R Zou, M Zur Nedden, L Zwalinski
This Letter presents a measurement of γγ→μ^{+}μ^{-} production in Pb+Pb collisions recorded by the ATLAS detector at the Large Hadron Collider at sqrt[s_{NN}]=5.02  TeV with an integrated luminosity of 0.49  nb^{-1}. The azimuthal angle and transverse momentum correlations between the muons are measured as a function of collision centrality. The muon pairs are produced from γγ through the interaction of the large electromagnetic fields of the nuclei. The contribution from background sources of muon pairs is removed using a template fit method...
November 23, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/30517620/homozygous-missense-mutation-l673p-in-adenylate-kinase-7-ak7-leads-to-primary-male-infertility-and-multiple-morphological-anomalies-of-the-flagella-but-not-to-primary-ciliary-dyskinesia
#6
Patrick Lorès, Charles Coutton, Elma El Khouri, Laurence Stouvenel, Maëlle Givelet, Lucie Thomas, Baptiste Rode, Alain Schmitt, Bruno Louis, Zeinab Sakheli, Marhaba Chaudhry, Angeles Fernandez-Gonzales, Alex Mitsialis, Denis Dacheux, Jean-Philippe Wolf, Jean-François Papon, Gérard Gacon, Estelle Escudier, Christophe Arnoult, Mélanie Bonhivers, Sergey N Savinov, Serge Amselem, Pierre F Ray, Emmanuel Dulioust, Aminata Touré
No abstract text is available yet for this article.
December 5, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/30516830/dietary-lipids-differentially-shape-nash-progression-and-the-transcriptome-of-kupffer-cells-and-infiltrating-macrophages
#7
Brett McGettigan, Rachel McMahan, David Orlicky, Matthew Burchill, Thomas Danhorn, Prashanth Francis, Lin Ling Cheng, Lucy Golden-Mason, Claudia Jakubzick, Hugo Rosen
A crucial component of non-alcoholic fatty liver disease (NAFLD) pathogenesis is lipid stress, which may contribute to hepatic inflammation and activation of innate immunity in the liver. However, little is known regarding how dietary lipids, including fat and cholesterol, may facilitate innate immune activation in vivo. We hypothesized that dietary fat and cholesterol drive NAFLD progression to steatohepatitis and hepatic fibrosis by altering the transcription and phenotype of hepatic macrophages METHODS: This hypothesis was tested by using RNA-seq methods to characterize and analyze sort-purified hepatic macrophage populations that were isolated from mice fed diets with varying amounts of fat and cholesterol RESULTS: The addition of cholesterol to a high fat diet triggered hepatic pathology reminiscent of advanced non-alcoholic steatohepatitis (NASH) in humans characterized by signs of cholesterol dysregulation, generation of oxidized LDL, increased recruitment of hepatic macrophages, and significant fibrosis...
December 5, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/30516130/identification-and-partial-characterization-of-a-novel-serpin-from-eudiplozoon-nipponicum-monogenea-polyopisthocotylea
#8
Pavel Roudnický, Jiří Vorel, Jana Ilgová, Michal Benovics, Adam Norek, Lucie Jedličková, Libor Mikeš, David Potěšil, Zbyněk Zdráhal, Jan Dvořák, Milan Gelnar, Martin Kašný
BACKGROUND: Serpins are a superfamily of serine peptidase inhibitors that participate in the regulation of many physiological and cell peptidase-mediated processes in all organisms (e.g. in blood clotting, complement activation, fibrinolysis, inflammation, and programmed cell death). It was postulated that in the blood-feeding members of the monogenean family Diplozoidae, serpins could play an important role in the prevention of thrombus formation, activation of complement, inflammation in the host, and/or in the endogenous regulation of protein degradation...
2018: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/30516064/a-study-of-the-description-of-exercise-programs-evaluated-in-randomized-controlled-trials-involving-people-with-fibromyalgia-using-different-reporting-tools-and-validity-of-the-tools-related-to-pain-relief
#9
Donguk Jo, Michael J Del Bel, Daniel McEwen, Jennifer O'Neil, Olivia S Mac Kiddie, Inmaculada C Álvarez-Gallardo, Lucie Brosseau
RATIONALE: Exercise programs for the management of fibromyalgia are well recognized as being effective. However, the incomplete descriptions of exercise programs make replication and implementation difficult. Also, existing reporting tools have not been validated in relation to pain relief as well as with each other. OBJECTIVES: This study aimed to evaluate the description of exercise programs in randomized control trials for the management of fibromyalgia using different assessment tools, and the correlations of each tool in relation to effectiveness of pain relief of fibromyalgia, and the correlations between each tool...
December 5, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/30515619/recent-advances-and-new-directions-in-measuring-theory-of-mind-in-autistic-adults
#10
Lucy Anne Livingston, Bethany Carr, Punit Shah
'Theory of Mind' (ToM) is the ability to attribute mental states to others to make sense of their behaviour. ToM research has informed understanding of (a)typical social behaviour, including the symptoms of autism spectrum disorder (ASD). This began with research on ToM in autistic children and there has been a noticeable increase in the study of ToM in autistic adults. However, methodological limitations in adult ToM research may be limiting its explanatory power of ASD symptoms and their management, therefore we discuss recent advances in measuring ToM aimed at addressing these issues...
December 4, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/30515429/a-patient-with-hemoptysis-and-the-sign-of-the-camalote
#11
Alex Studemeister, Marcos N Alvarez, Lucy Studemeister
A 30-year-old woman presenting with hemoptysis followed by acute respiratory distress developed a diagnostic pulmonary radiographic finding, called the sign of the camalote, indicative of ruptured hydatid cyst. Her computed tomography scan demonstrated the characteristic detached parasitic membrane floating on cystic fluid, reminiscent of Amazonian camalote leaves. She was managed successfully surgically. Ruptured hydatid cysts may present as a diagnostic challenge, in which the sign of the camalote may provide an important clue for this serious complication...
November 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/30514380/first-report-on-nasal-myiasis-in-an-alpaca-vicugna-pacos-a-case-report
#12
Teresa Maria Punsmann, Lucie Marie Grimm, Carolin Reckmann, Cornelia Schwennen, Matthias Gerhard Wagener, Martin Ganter
BACKGROUND: An infestation of bot fly larvae causes myiasis which is known to cause respiratory symptoms in ruminants. There are reports of bot fly larvae in llamas, but to our knowledge there are no previous reports of nasal myiasis due to bot flies in alpacas ("Vicugna pacos"). CASE PRESENTATION: The following case report describes a neutered male alpaca showing sneezing and mild nasal discharge. Endoscopic examination of the upper respiratory tract revealed bot fly larvae in one nostril...
December 4, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/30514350/landscape-structure-affects-the-prevalence-and-distribution-of-a-tick-borne-zoonotic-pathogen
#13
Caroline Millins, Eleanor R Dickinson, Petra Isakovic, Lucy Gilbert, Agnieszka Wojciechowska, Victoria Paterson, Feng Tao, Martin Jahn, Elizabeth Kilbride, Richard Birtles, Paul Johnson, Roman Biek
BACKGROUND: Landscape structure can affect pathogen prevalence and persistence with consequences for human and animal health. Few studies have examined how reservoir host species traits may interact with landscape structure to alter pathogen communities and dynamics. Using a landscape of islands and mainland sites we investigated how natural landscape fragmentation affects the prevalence and persistence of the zoonotic tick-borne pathogen complex Borrelia burgdorferi (sensu lato), which causes Lyme borreliosis...
December 4, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/30513551/microplastic-ingestion-ubiquitous-in-marine-turtles
#14
Emily M Duncan, Annette C Broderick, Wayne J Fuller, Tamara S Galloway, Matthew H Godfrey, Mark Hamann, Colin J Limpus, Penelope K Lindeque, Andrew G Mayes, Lucy C M Omeyer, David Santillo, Robin T E Snape, Brendan J Godley
Despite concerns regarding the environmental impacts of microplastics, knowledge of the incidence and levels of synthetic particles in large marine vertebrates is lacking. Here, we utilize an optimized enzymatic digestion methodology, previously developed for zooplankton, to explore whether synthetic particles could be isolated from marine turtle ingesta. We report the presence of synthetic particles in every turtle subjected to investigation (n = 102) which included individuals from all seven species of marine turtle, sampled from three ocean basins (Atlantic [ATL]: n = 30, four species; Mediterranean (MED): n = 56, two species; Pacific (PAC): n = 16, five species)...
December 4, 2018: Global Change Biology
https://www.readbyqxmd.com/read/30513514/the-management-of-acute-ischemic-strokes-and-the-prevalence-of-large-vessel-occlusion-in-left-ventricular-assist-device
#15
Cory J Rice, Sung-Min Cho, Lucy Q Zhang, Catherine Hassett, Randall C Starling, Ken Uchino
BACKGROUND: Ischemic and hemorrhagic strokes are frequent complications among those with left ventricular assist device (LVAD). Scarce data exist regarding the prevalence of acute large vessel occlusion (LVO) and treatment of acute ischemic stroke (AIS) in this setting. METHODS: We reviewed prospectively collected data of LVAD patient registry from a single, tertiary center from October 2004 to November 2016. Among those with AIS complications, patients were divided into early stroke (during implantation hospitalization) and late stroke (post-discharge) groups, and neuroimaging was reviewed and data on acute stroke therapy were collected...
December 4, 2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/30513012/prevalence-of-reduced-bone-mineral-density-in-adults-with-coeliac-disease-are-we-missing-opportunities-for-detection-in-patients-below-50-years-of-age
#16
Lucy Pritchard, Sophia Wilson, Jill Griffin, Geraldine Pearce, Iain A Murray, Stephen Lewis
OBJECTIVE: There are little data on the prevalence of reduced bone mineral density (BMD) in young adult patients with coeliac disease; guidelines do not support routine investigation of these patients. We assessed the prevalence of reduced BMD in our patients by age. PATIENTS AND METHODS: Prospective observational study of 260 coeliac patients having DXA one year after commencing gluten-free diet. Nonparametric tests and regression were used. RESULTS: Median age was 51years, BMI 24 and 85 (32...
December 4, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/30512936/orthogonal-middle-up-approaches-for-the-characterization-of-the-glycan-heterogeneity-of-etanercept-by-hydrophilic-interaction-chromatography-coupled-to-high-resolution-mass-spectrometry
#17
Valentina D'Atri, Lucie Nováková, Szabolcs Fekete, Dwight R Stoll, Matthew Allen Lauber, Alain Beck, Davy Guillarme
Etanercept is a recombinant Fc-fusion protein widely used to treat rheumatic diseases. This protein is highly glycosylated and contains numerous O- and N-glycosylation sites. Since glycosylation is recognized as an important critical quality attribute (CQA) that can affect immunogenicity, solubility, and stability of Fc-fusion proteins, it should be thoroughly characterized. In this work, hydrophilic interaction chromatography (HILIC) was combined with high resolution mass spectrometry (HRMS) by using a QTOF/MS instrument to assess glycosylation of etanercept at the middle-up level of analysis (fragments of circa 25-30 kDa)...
December 4, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/30511492/back-on-track-the-challenges-of-implementing-a-small-place-based-collective-impact-initiative
#18
Lucy Demant, Jessica Lawrence
ISSUES ADDRESSED: Back on Track (BoT) was developed as pilot to provide an integrated service response to twenty at-risk young people residing in a metro Melbourne housing estate. For this cohort, traditional welfare sector interventions were proving ineffective, with the siloed nature of the sector identified as a key barrier to effective engagement. METHODS: Developed as an offshoot of an established CI project, the Education Engagement Partnership (EEP), BoT used Collective Impact (CI) methodology to inform project development...
December 2018: Health Promotion Journal of Australia
https://www.readbyqxmd.com/read/30510424/cognitive-functioning-in-patients-treated-with-electroconvulsive-therapy
#19
Lucie Kalisova, Marketa Kubinova, Jiri Michalec, Jakub Albrecht, Katerina Madlova, Jiri Raboch
Background: Electroconvulsive therapy (ECT) is an effective treatment method for severe mental illnesses. ECT has gone through significant modernization. Side effects of ECT have largely decreased. Temporary disturbance of cognitive performance can be still present as a side effect of electroconvulsive treatment. Methods: Cognitive functioning in the sample of patients with severe and acute mental illness treated with electroconvulsive therapy (ECT) was assessed...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/30510331/the-effect-of-supplementary-ultraviolet-wavelengths-on-broiler-chicken-welfare-indicators
#20
Charlotte James, Lucy Asher, Katherine Herborn, Julian Wiseman
Qualities of the light environment are important for good welfare in a number of species. In chickens, UVA light is visible and may facilitate flock interactions. UVB wavelengths promote endogenous vitamin D synthesis, which could support the rapid skeletal development of broiler chickens. The aim of the study was to investigate the impacts of Ultraviolet wavelengths (UV) on welfare indicators in broiler chickens. Day-old Ross 308 birds reared under commercially representative conditions were randomly assigned to one of three lighting treatments: A) White Light Emitting Diode (LED) and supplementary UVA LED lighting (18-hour photoperiod); B) White LED with supplementary UVA and UVB fluorescent lighting providing 30 micro watts/cm2 UVB at bird level (on for 8 h of the total photoperiod to avoid over-exposure of UVB); C) White LED control group, representative of farm conditions (18-hour photoperiod)...
December 2018: Applied Animal Behaviour Science
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