Ekawat Vichayanrat, Fernanda Valerio, Shiwen Koay, Eduardo De Pablo-Fernandez, Jalesh Panicker, Huw Morris, Kailash Bhatia, Viorica Chelban, Henry Houlden, Niall Quinn, Judith Navarro-Otano, Yasuo Miki, Janice Holton, Thomas Warner, Christopher Mathias, Valeria Iodice
BACKGROUND AND OBJECTIVES: Nonmotor features precede motor symptoms in many patients with multiple system atrophy (MSA). However, little is known about differences between the natural history, progression, and prognostic factors for survival in patients with MSA with nonmotor vs motor presentations. We aimed to compare initial symptoms, disease progression, and clinical features at final evaluation and investigate differences in survival and natural history between patients with MSA with motor and nonmotor presentations...
September 13, 2022: Neurology