keyword
MENU ▼
Read by QxMD icon Read
search

Artificial organs

keyword
https://www.readbyqxmd.com/read/29334188/soft-artificial-bladder-detrusor
#1
Xuxu Yang, Chengrui An, Shuting Liu, Tingyu Cheng, Varitsara Bunpetch, Yixiao Liu, Shurong Dong, Shijian Li, Xiaohui Zou, Tiefeng Li, Hongwei Ouyang, Zhaohui Wu, Wei Yang
Developing soft devices for invasive procedures bears great importance for human health. The softness and large strain actuation of responsive hydrogels promise the potential to fabricate soft devices, which can attach on and assist to the function of organs. The key challenges lie in the fabrication of soft devices with robust actuating ability and biocompatibility to the attached organ. This paper presents a solution that integrates the thermoresponsive hydrogel membrane with flexible electronics and silk scaffold into a balloon-like soft device...
January 15, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29330665/a-synthetic-pathway-for-the-production-of-2-hydroxyisovaleric-acid-in-escherichia-coli
#2
Seokjung Cheong, James M Clomburg, Ramon Gonzalez
Synthetic biology, encompassing the design and construction of novel artificial biological pathways and organisms and the redesign of existing natural biological systems, is rapidly expanding the number of applications for which biological systems can play an integral role. In the context of chemical production, the combination of synthetic biology and metabolic engineering approaches continues to unlock the ability to biologically produce novel and complex molecules from a variety of feedstocks. Here, we utilize a synthetic approach to design and build a pathway to produce 2-hydroxyisovaleric acid in Escherichia coli and demonstrate how pathway design can be supplemented with metabolic engineering approaches to improve pathway performance from various carbon sources...
January 12, 2018: Journal of Industrial Microbiology & Biotechnology
https://www.readbyqxmd.com/read/29328804/replacement-of-the-nose
#3
Harold Ellis
Today's reconstructive surgeons may not be aware that replacement of the nose was carried out successfully as long ago as the 16th century by the surgeon Gaspar Taliacozzo of Bologna, Italy, who published a detailed and illustrated account of his operation in 1597. This procedure comprised raising a flap of skin from the upper arm to reconstruct the nose. The arm was kept in place, with the hand resting on the patient's head, using elaborate splinting until adherence had taken place; the flap was then detached from the donor arm...
May 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29326985/use-of-an-autonomous-surface-vehicle-reveals-small-scale-diel-vertical-migrations-of-zooplankton-and-susceptibility-to-light-pollution-under-low-solar-irradiance
#4
Martin Ludvigsen, Jørgen Berge, Maxime Geoffroy, Jonathan H Cohen, Pedro R De La Torre, Stein M Nornes, Hanumant Singh, Asgeir J Sørensen, Malin Daase, Geir Johnsen
Light is a major cue for nearly all life on Earth. However, most of our knowledge concerning the importance of light is based on organisms' response to light during daytime, including the dusk and dawn phase. When it is dark, light is most often considered as pollution, with increasing appreciation of its negative ecological effects. Using an Autonomous Surface Vehicle fitted with a hyperspectral irradiance sensor and an acoustic profiler, we detected and quantified the behavior of zooplankton in an unpolluted light environment in the high Arctic polar night and compared the results with that from a light-polluted environment close to our research vessels...
January 2018: Science Advances
https://www.readbyqxmd.com/read/29325802/utilization-of-large-volume-zwitterionic-hydrophilic-interaction-liquid-chromatography-for-the-analysis-of-polar-pharmaceuticals-in-aqueous-environmental-samples-benefits-and-limitations
#5
Lise Boulard, Georg Dierkes, Thomas Ternes
Benefits and limitations of HILIC were studied for the analysis of extreme polar organic contaminants in aqueous environmental matrices. A sensitive analytical method was developed and validated for the detection of 11 pharmaceuticals, 15 pharmaceutical metabolites and transformation products and the artificial sweetener acesulfame in aqueous environmental samples. The analytical method consisted of a simple and non-specific sample preparation based on freeze-drying followed by detection with large injection volume (70 μL) zwitterionic HILIC-ESI-MS/MS...
December 11, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29325692/ontogenetic-and-temperature-dependent-changes-in-tolerance-to-hypoxia-and-hydrogen-sulfide-during-the-early-life-stages-of-the-manila-clam-ruditapes-philippinarum
#6
Keita Kodama, Mitsuyasu Waku, Ryota Sone, Dai Miyawaki, Toshiro Ishida, Tetsuji Akatsuka, Toshihiro Horiguchi
Wind-induced upwelling of hypoxic waters containing hydrogen sulfide (H2S) sometimes causes mass mortalities of aquatic organisms inhabiting coastal areas, including the hypoxia-tolerant Manila clam Ruditapes philippinarum. We examined the tolerance of Manila clam to H2S under controlled laboratory conditions. Larvae and juveniles obtained by artificial fertilization or from a wild population were exposed to normoxic or to hypoxic water with or without un-ionized H2S (concentrations, 0.2-52.2 mg/L). Twenty-four-hour exposure experiments revealed ontogenetic changes in the clam's tolerance to H2S exposure: tolerance was enhanced from the larval stages to juveniles just after settlement but was attenuated as juveniles grew...
January 2, 2018: Marine Environmental Research
https://www.readbyqxmd.com/read/29324935/right-putamen-and-age-are-the-most-discriminant-features-to-diagnose-parkinson-s-disease-by-using-123i-fp-cit-brain-spet-data-by-using-an-artificial-neural-network-classifier-a-classification-tree-clt
#7
S Cascianelli, C Tranfaglia, M L Fravolini, F Bianconi, M Minestrini, S Nuvoli, N Tambasco, M E Dottorini, B Palumbo
OBJECTIVE: The differential diagnosis of Parkinson's disease (PD) and other conditions, such as essential tremor and drug-induced parkinsonian syndrome or normal aging brain, represents a diagnostic challenge. 123I-FP-CIT brain SPET is able to contribute to the differential diagnosis. Semiquantitative analysis of radiopharmaceutical uptake in basal ganglia (caudate nuclei and putamina) is very useful to support the diagnostic process. An artificial neural network classifier using 123I-FP-CIT brain SPET data, a classification tree (CIT), was applied...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29323659/production-deformation-and-mechanical-investigation-of-magnetic-alginate-capsules
#8
Elena Zwar, Andre Kemna, Lena Richter, Patrick Degen, Heinz Rehage
In this article we investigated the deformation of alginate capsules in magnetic fields. The sensitivity to magnetic forces was realised by encapsulating an oil in water emulsion, where the oil droplets contained dispersed magnetic nanoparticles. We solved calcium ions in the aqueous emulsion phase, which act as crosslinking compounds for forming thin layers of alginate membranes. This encapsulating technique allows the production of flexible capsules with an emulsion as the capsule core. It is important to mention that the magnetic nanoparticles were stable and dispersed throughout the complete process, which is an important difference to most magnetic alginate-based materials...
January 11, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29318963/nanodiagnostics-and-nanodelivery-applications-in-genetic-alterations
#9
Maria Sofia Falzarano, Cristina Flesia, Roberta Cavalli, Caterina Guiot, Alessandra Ferlini
Background Genetic alterations cause hereditary diseases (HDs) with a wide range of incidences. Some, like cystic fibrosi, occur frequently (1/1,000 newborns), whilst others, such as Pompe disease and other metabolic disorders are very rare (1/100,000 newborns). They are well under the threshold of 1/3,000, denoted by the European Community as rare diseases (RDs). Genetic alterations are also associated with multifactorial disorders like diabetes, and underline both somatic and germline mutations in cancer...
January 10, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29318897/in-vitro-and-in-silico-characterisation-of-lactobacillus-paraplantarum-d2-1-a-starter-culture-for-soymilk-fermentation
#10
Akihito Endo, Fuko Sasaki, Shintaro Maeno, Yu Kanesaki, Yu Hamaguchi, Glaezel Angelique Torres, Satoru Tomita, Junichi Nakagawa
Soymilk contains several functional nutrients and is thus a promising ingredient for production of functional foods. The present research aimed to study starter properties, functional characteristics and safety of Lactobacillus paraplantarum D2-1, a promising starter culture for soymilk fermentation. Strain D2-1 actively fermented soymilk within 24 h but had weak activity of additional acid production after 7 d. Succinate and acetoin, which could be linked to flavour and taste, were accumulated in fermented soymilk...
January 10, 2018: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/29318846/-a-survey-on-ecological-environment-of-wild-adiantum-reniforme-var-sinense-in-three-gorges-reservoir-region
#11
Zhong-de Xie, Han Jia, Shao-Zhi Fu, Wen-Yuan Gao, Zhi-Wei Zhang, Wei Sun
The study aims at investigating the ecological environment Adiantum reniforme var. sinense of in Three Gorges Reservoir region, and providing a reference basis for the protection of resources and artificial cultivation of A. reniforme var. sinense. By using the method of investigation, field survey and experimental analysis, the vegetation, natural geographical environment, climate, soil nutrients of A. reniforme var. sinense were studied and analyzed. The survey found that A. reniforme var. sinense distribution area reduced fast in Three Gorges region, a lot of distribution has diminished and vanished due to excessive digging, currently only in 3 towns of Wanzhou there exist 4 wild distribution areas...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29316469/numerical-research-on-the-effects-the-skyglow-could-have-in-phytochromes-and-rqe-photoreceptors-of-plants
#12
H A Solano-Lamphar, M Kocifaj
The increase of artificial light at night has a terrible impact on organisms with nightlife patterns such as a migration, nutrition, reproduction and collective interaction. Plants are not free from this issue as they have life cycle events occurring not only yearly but also daily. Such events relate to daytime variations with seasons in which the flowers of deciduous trees bloom and the leaves of certain trees fall off and change color. A response of plants to artificial light at night still remains poorly quantified; but recent scientific research suggest that skyglow can disturb plants processes...
January 6, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29315551/the-impact-of-artificial-selection-on-morphological-integration-in-the-appendicular-skeleton-of-domestic-horses
#13
Pauline Hanot, Anthony Herrel, Claude Guintard, Raphaël Cornette
The relationships between the different component parts of organisms, such as the sharing of common development or function, produce a coordinated variation between the different traits. This morphological integration contributes to drive or constrain morphological variation and thus impacts phenotypic diversification. Artificial selection is known to contribute significantly to phenotypic diversification of domestic species. However, little attention has been paid to its potential impact on integration patterns...
January 8, 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/29315219/proposal-of-a-method-to-determine-the-correlation-between-total-suspended-solids-and-dissolved-organic-matter-in-water-bodies-from-spectral-imaging-and-artificial-neural-networks
#14
Maurício R Veronez, Lucas S Kupssinskü, Tainá T Guimarães, Emilie C Koste, Juarez M da Silva, Laís V de Souza, William F M Oliverio, Rogélio S Jardim, Ismael É Koch, Jonas G de Souza, Luiz Gonzaga, Frederico F Mauad, Leonardo C Inocencio, Fabiane Bordin
Water quality monitoring through remote sensing with UAVs is best conducted using multispectral sensors; however, these sensors are expensive. We aimed to predict multispectral bands from a low-cost sensor (R, G, B bands) using artificial neural networks (ANN). We studied a lake located on the campus of Unisinos University, Brazil, using a low-cost sensor mounted on a UAV. Simultaneously, we collected water samples during the UAV flight to determine total suspended solids (TSS) and dissolved organic matter (DOM)...
January 9, 2018: Sensors
https://www.readbyqxmd.com/read/29314837/tetrabase-a-side-chain-independent-statistical-energy-for-designing-realistically-packed-protein-backbones
#15
Huanyu Chu, Haiyan Liu
To construct backbone structures of high designability is a primary aspect of computational protein design. We report here a side chain-independent statistical energy that aims at realistic modeling of through-space packing of polypeptide backbones. To mitigate the lack of explicit amino acid side chains, the model treats the inter-backbone site packing as being dependent on peptide local conformation. In addition, new variables suitable for statistical analysis, one for relative orientation and another for distance, have been introduced to represent the inter-site geometry based on the asymmetrical tetrahedron organization of distinct chemical groups surrounding the Cα-carbon atoms...
January 9, 2018: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29314192/parvalbumin-producing-striatal-interneurons-receive-excitatory-inputs-onto-proximal-dendrites-from-the-motor-thalamus-in-male-mice
#16
Yasutake Nakano, Fuyuki Karube, Yasuharu Hirai, Kenta Kobayashi, Hiroyuki Hioki, Shinichiro Okamoto, Hiroshi Kameda, Fumino Fujiyama
In rodents, the dorsolateral striatum regulates voluntary movement by integrating excitatory inputs from the motor-related cerebral cortex and thalamus to produce contingent inhibitory output to other basal ganglia nuclei. Striatal parvalbumin (PV)-producing interneurons receiving this excitatory input then inhibit medium spiny neurons (MSNs) and modify their outputs. To understand basal ganglia function in motor control, it is important to reveal the precise synaptic organization of motor-related cortical and thalamic inputs to striatal PV interneurons...
January 4, 2018: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29309118/proton-coupled-electron-transfer-in-artificial-photosynthetic-systems
#17
S Jimena Mora, Emmanuel Odella, Gary F Moore, Devens Gust, Thomas A Moore, Ana L Moore
Artificial photosynthetic constructs can in principle operate more efficiently than natural photosynthesis because they can be rationally designed to optimize solar energy conversion for meeting human demands rather than the multiple needs of an organism competing for growth and reproduction in a complex ecosystem. The artificial photosynthetic constructs described in this Account consist primarily of covalently linked synthetic chromophores, electron donors and acceptors, and proton donors and acceptors that carry out the light absorption, electron transfer, and proton-coupled electron transfer (PCET) processes characteristic of photosynthetic cells...
January 8, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29305983/learning-how-to-use-iam-chromatography-for-predicting-permeability
#18
Giuseppe Ermondi, Maura Vallaro, Giulia Caron
The interest for IAM (Immobilized Artificial Membranes) chromatography in the prediction of drug permeability is increasing. Here we firstly set-up a dataset of 253 molecules including neutral and ionized drugs and few organic compounds for which we either measured or retrieved from the literature IAM.PC.DD2 log KwIAM data. Then we applied block relevance (BR) analysis to extract from PLS models the relative contribution of intermolecular forces governing log KwIAM and Δlog KwIAM (a combined descriptor calculated from log KwIAM)...
January 3, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29304008/biological-control-products-for-aflatoxin-prevention-in-italy-commercial-field-evaluation-of-atoxigenic-aspergillus-flavus-active-ingredients
#19
Antonio Mauro, Esther Garcia-Cela, Amedeo Pietri, Peter J Cotty, Paola Battilani
Since 2003, non-compliant aflatoxin concentrations have been detected in maize produced in Italy. The most successful worldwide experiments in aflatoxin prevention resulted from distribution of atoxigenic strains of Aspergillusflavus to displace aflatoxin-producers during crop development. The displacement results in lower aflatoxin concentrations in harvested grain. The current study evaluated in field performances of two atoxigenic strains of A. flavus endemic to Italy in artificially inoculated maize ears and in naturally contaminated maize...
January 5, 2018: Toxins
https://www.readbyqxmd.com/read/29303248/multifunctional-sensor-based-on-porous-carbon-derived-from-metal-organic-frameworks-for-real-time-health-monitoring
#20
Xin-Hua Zhao, Sai-Nan Ma, Hui Long, Huiyu Yuan, Chun Yin Tang, Ping Kwong Cheng, Yuen Hong Tsang
Flexible and sensitive sensors that can detect external stimuli such as pressure, temperature, and strain are essential components for applications in health diagnosis and artificial intelligence. Multifunctional sensors with the capabilities of sensing pressure and temperature simultaneously are highly desirable for health monitoring. Here, we have successfully fabricated a flexible and simply structured bimodal sensor based on metal-organic frameworks (MOFs) derived porous carbon (PC) and polydimethylsiloxane (PDMS) composite...
January 5, 2018: ACS Applied Materials & Interfaces
keyword
keyword
17081
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"