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https://www.readbyqxmd.com/read/28454480/immobilization-of-ph-sensitive-cdte-quantum-dots-in-a-poly-acrylate-hydrogel-for-microfluidic-applications
#1
M Franke, S Leubner, A Dubavik, A George, T Savchenko, C Pini, P Frank, D Melnikau, Y Rakovich, N Gaponik, A Eychmüller, A Richter
Microfluidic devices present the basis of modern life sciences and chemical information processing. To control the flow and to allow optical readout, a reliable sensor material that can be easily utilized for microfluidic systems is in demand. Here, we present a new optical readout system for pH sensing based on pH sensitive, photoluminescent glutathione capped cadmium telluride quantum dots that are covalently immobilized in a poly(acrylate) hydrogel. For an applicable pH sensing the generated hybrid material is integrated in a microfluidic sensor chip setup...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28454165/light-field-endoscopy-and-its-parametric-description
#2
Jingdan Liu, Daniel Claus, Tingfa Xu, Thorben Keßner, Alois Herkommer, Wolfgang Osten
In this Letter, we demonstrate the application of light field imaging to endoscopy. By introducing a microlens array into the image plane of a conventional endoscope, the 4D light field can be captured in one snapshot. This information can be used to obtain perspective images and to digitally refocus to different planes. These features allow for the recovery of 3D information in minimally invasive surgery. Important optical setup and performance parameters are derived to enable task specific engineering of the light field imaging system...
May 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28454163/image-recovery-from-defocused-2d-fluorescent-images-in-multimodal-digital-holographic-microscopy
#3
Xiangyu Quan, Osamu Matoba, Yasuhiro Awatsuji
A technique of three-dimensional (3D) intensity retrieval from defocused, two-dimensional (2D) fluorescent images in the multimodal digital holographic microscopy (DHM) is proposed. In the multimodal DHM, 3D phase and 2D fluorescence distributions are obtained simultaneously by an integrated system of an off-axis DHM and a conventional epifluorescence microscopy, respectively. This gives us more information of the target; however, defocused fluorescent images are observed due to the short depth of field. In this Letter, we propose a method to recover the defocused images based on the phase compensation and backpropagation from the defocused plane to the focused plane using the distance information that is obtained from a 3D phase distribution...
May 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28454137/dynamic-stark-shift-induced-by-a-single-photon-packet
#4
D Valente, F Brito, T Werlang
The dynamic Stark shift results from the interaction of an atom with the electromagnetic field. We show how a propagating single-photon wave packet can induce a time-dependent dynamical Stark shift on a two-level system (TLS). A non-perturbative fully quantum treatment is employed, where the quantum dynamics of both the field and the TLS are analyzed. We also provide the means to experimentally access such time-dependent frequency by measuring the interference pattern in the electromagnetic field inside a 1D waveguide...
May 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28454068/biochar-based-water-treatment-systems-as-a-potential-low-cost-and-sustainable-technology-for-clean-water-provision
#5
REVIEW
Willis Gwenzi, Nhamo Chaukura, Chicgoua Noubactep, Fungai N D Mukome
Approximately 600 million people lack access to safe drinking water, hence achieving Sustainable Development Goal 6 (Ensure availability and sustainable management of water and sanitation for all by 2030) calls for rapid translation of recent research into practical and frugal solutions within the remaining 13 years. Biochars, with excellent capacity to remove several contaminants from aqueous solutions, constitute an untapped technology for drinking water treatment. Biochar water treatment has several potential merits compared to existing low-cost methods (i...
April 25, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28454021/reactive-mineral-removal-relative-to-soil-organic-matter-heterogeneity-and-implications-for-organic-contaminant-sorption
#6
Fangfang Li, Bo Pan, Ni Liang, Zhaofeng Chang, Yuwei Zhou, Lin Wang, Hao Li, Baoshan Xing
Soil organic matter (SOM) is generally treated as a static compartment of soil in pollutant fate studies. However, SOM might be altered or fractionated in soil systems, and the details of SOM property/composition changes when coupled with contaminant behavior are unknown. In this study, a mild acid treatment was adopted to remove reactive minerals and partially remove SOM components. After acid treatment, biomarker signatures showed that lignin-derived phenols were released and black carbon (as suggested by benzene-polycarboxylic acids) and lipids were enriched...
April 25, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28453984/functional-and-genetic-evidence-that-nucleoside-transport-is-highly-conserved-in-leishmania-species-implications-for-pyrimidine-based-chemotherapy
#7
Khalid J H Alzahrani, Juma A M Ali, Anthonius A Eze, Wan Limm Looi, Daniel N A Tagoe, Darren J Creek, Michael P Barrett, Harry P de Koning
Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various Leishmania species possess similar pyrimidine transporters capable of drug uptake. Here, we report a comprehensive characterization of pyrimidine transport in L. major and L. mexicana. In both species, two transporters for uridine/adenosine were detected, one of which also transported uracil and the antimetabolites 5-fluoruracil (5-FU) and 5F,2'deoxyuridine (5F,2'dUrd), and was designated uridine-uracil transporter 1 (UUT1); the other transporter mediated uptake of adenosine, uridine, 5F,2'dUrd and thymidine and was designated Nucleoside Transporter 1 (NT1)...
April 20, 2017: International Journal for Parasitology, Drugs and Drug Resistance
https://www.readbyqxmd.com/read/28453916/digital-technology-and-clinical-decision-making-in-depression-treatment-current-findings-and-future-opportunities
#8
REVIEW
Kevin A Hallgren, Amy M Bauer, David C Atkins
Clinical decision making encompasses a broad set of processes that contribute to the effectiveness of depression treatments. There is emerging interest in using digital technologies to support effective and efficient clinical decision making. In this paper, we provide "snapshots" of research and current directions on ways that digital technologies can support clinical decision making in depression treatment. Practical facets of clinical decision making are reviewed, then research, design, and implementation opportunities where technology can potentially enhance clinical decision making are outlined...
April 28, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28453901/quasi-static-acoustic-tweezing-thromboelastometry
#9
R G Holt, D Luo, N Gruver, D B Khismatullin
BACKGROUND: Thromboelastography is widely used as a tool to assess the coagulation status of surgical patients. It allows observation of changes in material properties of whole blood, beginning with early stages of clot formation and ending with clot lysis. However, the contact activation of the coagulation cascade at surfaces of thromboelastographic systems leads to inherent variability and unreliability in predicting bleeding or thrombosis risks. OBJECTIVES: To develop acoustic tweezing thromboelastometry as a noncontact method for perioperative assessment of blood coagulation...
April 28, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28453863/use-of-a-geographic-information-system-to-assess-accessibility-to-health-facilities-providing-emergency-obstetric-and-newborn-care-in-bangladesh
#10
Mahbub E Chowdhury, Taposh K Biswas, Monjur Rahman, Kamal Pasha, Mollah A Hossain
OBJECTIVE: To use a geographic information system (GIS) to determine accessibility to health facilities for emergency obstetric and newborn care (EmONC) and compare coverage with that stipulated by UN guidelines (5 EmONC facilities per 500 000 individuals, ≥1 comprehensive). METHODS: A cross-sectional study was undertaken of all public facilities providing EmONC in 24 districts of Bangladesh from March to October 2012. Accessibility to each facility was assessed by applying GIS to estimate the proportion of catchment population (comprehensive 500 000; basic 100 000) able to reach the nearest facility within 2 hours and 1 hour of travel time, respectively, by existing road networks...
April 28, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28453827/factors-constraining-patient-engagement-in-implantable-medical-device-discussions-and-decisions-interviews-with-physicians
#11
Anna R Gagliardi, Pascale Lehoux, Ariel Ducey, Anthony Easty, Sue Ross, Chaim M Bell, Patricia Trbovich, Julie Takata, David R Urbach
Objective: Patient engagement (PE) is warranted when treatment risks and outcomes are uncertain, as is the case for higher risk medical devices. Previous research found that patients were not engaged in discussions or decisions about implantable medical devices. This study explored physician views about engaging patients in such discussions. Design: Qualitative interviews using a basic descriptive approach. Setting: Canada. Participants: Practicing cardiovascular and orthopaedic physicians...
April 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28453689/periodontal-disease-edentulism-and-pancreatic-cancer-a-meta-analysis
#12
P Maisonneuve, S Amar, A B Lowenfels
Background: Periodontal disease (PD), now our commonest infectious disorder leads to tooth loss, and has been linked to various systemic diseases, including various types of cancer. The aim of this study is to provide a systematic review and a meta-analysis of the relationship between PD, edentulism, and pancreatic cancer (PC). Patients and methods: From an initial review of 327 references we selected eight studies concerning periodontitis or edentulism with sufficient quantitative information to allow us to examine the risk of PC...
May 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28453667/linearity-of-network-proximity-measures-implications-for-set-based-queries-and-significance-testing
#13
Sean Maxwell, Mark R Chance, Mehmet Koyutürk
Motivation: In recent years, various network proximity measures have been proposed to facilitate the use of biomolecular interaction data in a broad range of applications. These applications include functional annotation, disease gene prioritization, comparative analysis of biological systems and prediction of new interactions. In such applications, a major task is the scoring or ranking of the nodes in the network in terms of their proximity to a given set of 'seed' nodes (e.g. a group of proteins that are identified to be associated with a disease, or are deferentially expressed in a certain condition)...
May 1, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28453627/patient-reported-physical-function-measures-in-cancer-clinical-trials
#14
Thomas M Atkinson, Angela M Stover, Daniel F Storfer, Rebecca M Saracino, Thomas A D'Agostino, Denise Pergolizzi, Konstantina Matsoukas, Yuelin Li, Ethan Basch
Patient-reported outcomes (PROs) are increasingly used to monitor treatment-related symptoms and physical function decrements in cancer clinical trials. As more patients enter survivorship, it is important to capture PRO physical function throughout trials to help restore pretreatment levels of function. We completed a systematic review of PRO physical function measures used in cancer clinical trials and evaluated their psychometric properties on the basis of guidelines from the US Food and Drug Administration...
April 27, 2017: Epidemiologic Reviews
https://www.readbyqxmd.com/read/28453613/functional-characterization-of-the-human-speech-articulation-network
#15
Alexandra Basilakos, Kimberly G Smith, Paul Fillmore, Julius Fridriksson, Evelina Fedorenko
A number of brain regions have been implicated in articulation, but their precise computations remain debated. Using functional magnetic resonance imaging, we examine the degree of functional specificity of articulation-responsive brain regions to constrain hypotheses about their contributions to speech production. We find that articulation-responsive regions (1) are sensitive to articulatory complexity, but (2) are largely nonoverlapping with nearby domain-general regions that support diverse goal-directed behaviors...
April 27, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28453561/a-webgis-platform-for-the-monitoring-of-farm-animal-genetic-resources-genmon
#16
Solange Duruz, Christine Flury, Giona Matasci, Florent Joerin, Ivo Widmer, Stéphane Joost
BACKGROUND: In 2007, the Food and Agriculture Organization of the United Nations (FAO) initiated the Global plan of action for Farm Animal Genetic Resources (FAnGR). The main goal of this plan is to reduce further loss of genetic diversity in farm animals, so as to protect and promote the diversity of farm animal resources. An important step to reach this goal is to monitor and prioritize endangered breeds in the context of conservation programs. METHODOLOGY/WEB PORTAL IMPLEMENTATION: The GENMON WebGIS platform is able to monitor FAnGR and to evaluate the degree of endangerment of livestock breeds...
2017: PloS One
https://www.readbyqxmd.com/read/28453433/diagnostic-accuracy-of-selective-3-t-mr-neurography-guided-retroperitoneal-genitofemoral-nerve-blocks-for-the-diagnosis-of-genitofemoral-neuralgia
#17
Jan Fritz, A Lee Dellon, Eric H Williams, Gedge D Rosson, Allan J Belzberg, Frederick E Eckhauser
Purpose To determine if 3-T magnetic resonance (MR) neurography-guided retroperitoneal genitofemoral nerve (GFN) blocks are safe and effective for the diagnosis of genitofemoral neuralgia. Materials and Methods Following institutional review board approval and informed consent, 26 subjects (16 men, 10 women; mean age, 42 years [range, 24-78 years]; mean body mass index, 28 kg/m(2) [range, 20-35 kg/m(2)]) with intractable groin pain were included. By using a 3-T MR imaging system, intermediate-weighted turbo spin-echo pulse sequences, and MR-conditional needles, diagnostic MR neurography-guided GFN blocks were performed in the retroperitoneum...
April 28, 2017: Radiology
https://www.readbyqxmd.com/read/28453402/evaluation-of-carbon-emission-reductions-promoted-by-private-driving-restrictions-based-on-afc-data-in-beijing
#18
Wandi Zhang, Feng Chen, Zijia Wang, Jianling Huang, Bo Wang
Public transportation automatic fare collection (AFC) systems are able to continuously record large amounts of passenger travel information, providing massive, low-cost data for research on regulations pertaining to public transport. This data can be used not only to analyze characteristics of passengers' trips but also to evaluate transport policies that promote a travel mode shift and emission reduction. In this study, models combining card, survey, and GIS data are established with a research focus on the private driving restriction policies being implemented in an ever-increasing number of cities...
April 28, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28453274/a-porous-array-of-clock-qubits
#19
Joseph M Zadrozny, Audrey T Gallagher, T David Harris, Danna E Freedman
The command of atomic-level spatial control over qubits, the fundamental units of both quantum information processing systems and quantum sensors, constitutes a crucial cross-field challenge. Toward this end, embedding electronic spin based qubits within the framework of a crystalline porous material is a promising approach to create precise arrays of qubits. Realizing porous hosts for qubits would also impact the emerging field of quantum sensing, whereby porosity enables analytes to infuse into a sensor matrix...
April 28, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28449485/prognostic-effects-of-preoperative-obstructive-pneumonitis-or-atelectasis-and-comparison-with-tumor-size-in-non-small-cell-lung-cancer
#20
Zhaofei Pang, Nan Ding, Wei Dong, Yang Ni, Tiehong Zhang, Xiao Qu, Jiajun Du, Qi Liu
BACKGROUND: In the eighth TNM staging system proposal, lung cancer with part or complete obstructive pneumonitis/atelectasis was classified to T2 category, and dividing lines of T category were changed. We conducted this study to search prognostic effect of preoperative obstructive pneumonitis/atelectasis and its comparison with tumor size. METHODS: We collected clinical characteristics, preoperative hematological indicators, follow-up information of 1,313 lung cancer patients...
March 2017: Journal of Thoracic Disease
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