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https://www.readbyqxmd.com/read/28107385/evaluating-the-significance-of-viscoelasticity-in-diagnosing-early-stage-liver-fibrosis-with-transient-elastography
#1
Jingxin Zhao, Fei Zhai, Jun Cheng, Qiong He, Jianwen Luo, Xueping Yang, Jinhua Shao, Huichun Xing
Transient elastography quantifies the propagation of a mechanically generated shear wave within a soft tissue, which can be used to characterize the elasticity and viscosity parameters of the tissue. The aim of our study was to combine numerical simulation and clinical assessment to define a viscoelastic index of liver tissue to improve the quality of early diagnosis of liver fibrosis. This is clinically relevant, as early fibrosis is reversible. We developed an idealized two-dimensional axisymmetric finite element model of the liver to evaluate the effects of different viscoelastic values on the propagation characteristics of the shear wave...
2017: PloS One
https://www.readbyqxmd.com/read/28107092/a-solid-pseudopapillary-neoplasm-of-the-pancreas-associated-with-igg4-related-pancreatitis
#2
Yuichiro Hatano, Keisuke Kawashima, Takuji Iwashita, Masaki Kimura, Masahito Shimizu, Akira Hara
A solid and cystic pancreatic lesion was incidentally found in a 62-year-old woman on abdominal computed tomography. The lesion was diagnosed as a solid pseudopapillary neoplasm by using endoscopic ultrasound-guided fine needle aspiration, and the tumor was resected. Histologically, the tumor cells had relatively small, round nuclei and papillary-like architecture in a hemorrhagic background. On immunohistochemical examination, the tumor cells were diffusely positive for nuclear β-catenin and cytoplasmic CD10...
November 1, 2016: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28105257/ultrasound-shear-wave-elastography-and-liver-fibrosis-a-prospective-multicenter-study
#3
Joyce Anyona Sande, Suleman Verjee, Sudhir Vinayak, Farin Amersi, Munir Ghesani
AIM: To assess the accuracy of shear wave elastography (SWE) alone and in combination with aminotransferase platelet ratio index (APRI) score in the staging of liver fibrosis. METHODS: A multicenter prospective study was conducted to assess the accuracy of SWE (medians) and APRI to predict biopsy results. The analysis focused on distinguishing the different stages of liver disease, namely, F0 from F1-4, F0-1 from F2-4, F0-2 from F3-4 and F0-3 from F4; F0-F1 from F2-F4 being of primary interest...
January 8, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/28104978/maximizing-the-endosonography-the-role-of-contrast-harmonics-elastography-and-confocal-endomicroscopy
#4
REVIEW
Andrada Seicean, Ofelia Mosteanu, Radu Seicean
New technologies in endoscopic ultrasound (EUS) evaluation have been developed because of the need to improve the EUS and EUS-fine needle aspiration (EUS-FNA) diagnostic rate. This paper reviews the principle, indications, main literature results, limitations and future expectations for each of the methods presented. Contrast-enhanced harmonic EUS uses a low mechanical index and highlights slow-flow vascularization. This technique is useful for differentiating solid and cystic pancreatic lesions and assessing biliary neoplasms, submucosal neoplasms and lymph nodes...
January 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28104945/neonatal-and-infantile-spinal-sonography-a-useful-investigation-often-underutilized
#5
Nikhil Nair, M Sreenivas, Arun K Gupta, Devasenathipathy Kandasamy, Manisha Jana
Sonography is an ideal, effective, noninvasive tool for evaluation of the spinal cord in neonatal and early infantile age groups owing to lack of ossification of the posterior elements of spine. Understanding normal anatomical appearances is a prerequisite for the interpretation of various pathologies of the spinal canal and its contents. This review elucidates normal appearances of the spinal cord in this age group, in both axial and sagittal planes. Usefulness of Doppler sonography is briefly discussed, and special emphasis is placed on normal anatomical variants that may mimic spinal abnormalities...
October 2016: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28104551/a-framework-for-analysis-of-linear-ultrasound-videos-to-detect-fetal-presentation-and-heartbeat
#6
M A Maraci, C P Bridge, R Napolitano, A Papageorghiou, J A Noble
Confirmation of pregnancy viability (presence of fetal cardiac activity) and diagnosis of fetal presentation (head or buttock in the maternal pelvis) are the first essential components of ultrasound assessment in obstetrics. The former is useful in assessing the presence of an on-going pregnancy and the latter is essential for labour management. We propose an automated framework for detection of fetal presentation and heartbeat from a predefined free-hand ultrasound sweep of the maternal abdomen. Our method exploits the presence of key anatomical sonographic image patterns in carefully designed scanning protocols to develop, for the first time, an automated framework allowing novice sonographers to detect fetal breech presentation and heartbeat from an ultrasound sweep...
January 10, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28104531/diagnosis-and-treatment-of-gouty-tophi-in-the-patellar-tendon-using-ultrasound-guided-needle-barbotage-a-case-report
#7
Ricardo E Colberg, Rachel B Geffen
A 73-year-old male presented with non-traumatic debilitating anterior left knee pain. Magnetic resonance imaging suggested a partial patellar tendon tear. However, ultrasound imaging revealed multiple small hyperechoic areas with posterior acoustic shadowing with intermixed hypoechoic fluid within the proximal patellar tendon, consistent with gouty tophi. The patient underwent ultrasound-guided needle barbotage of the tophi. Gout was confirmed by the presence of uric acid crystals in the aspirate. He had immediate pain relief...
January 16, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28103204/transthoracic-ultrasonography-for-the-immunocompromised-patient-a-pilot-project-that-introduces-transthoracic-ultrasonography-for-the-follow-up-of-hematological-patients-in-romania
#8
Ioana Frinc, Petru Ilies, Florin Zaharie, Delia Dima, Alina Tanase, Ljubomir Petrov, Alexandru Irimie, Cristian Berce, Cosmin Lisencu, Ioana Berindan-Neagoe, Ciprian Tomuleasa, Anca Bojan
In the last decade, there is significant progress in clinical hematology with the discovery of targeted molecules and thus the achievement of both hematologic and molecular responses. Nevertheless, chemotherapy remains the treatment of choice for many types of hematological malignancies. Aggressive chemotherapy leads to immunosuppression, accompanied by a high rate of infections and an increased rate of treatment-related mortality. Invasive fungal infections, as well as more common bacterial and viral infections are frequent in immunocompromised patients as they are difficult to diagnose and treat...
January 18, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28102963/diagnostic-value-of-endobronchial-ultrasound-elastography-for-the-differentiation-of-benign-and-malignant-intrathoracic-lymph-nodes
#9
Potjanee Korrungruang, Viboon Boonsarngsuk
BACKGROUND AND OBJECTIVE: Endobronchial ultrasound (EBUS) findings can be used for benign/malignant differentiation of lymph nodes (LNs). Recently, EBUS elastography has been introduced as a complementary modality in the evaluation of intrathoracic lymphadenopathy. We evaluated the ability of EBUS elastography to differentiate between benign and malignant LNs. METHODS: A prospective study was conducted on patients sent for evaluation of intrathoracic lymphadenopathy...
January 19, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28102592/six-uneventful-pregnancy-outcomes-in-an-extended-vascular-ehlers-danlos-syndrome-family
#10
Annette F Baas, Wilko Spiering, Frans L Moll, Lieve Page-Christiaens, Ingrid C M Beenakkers, Dennis Dooijes, Evert-Jan P A Vonken, Jasper J van der Smagt, Nine V Knoers, Steven V Koenen, Joost A van Herwaarden, Gertjan Tj Sieswerda
Vascular Ehlers-Danlos Syndrome (vEDS) is caused by heterozygous mutations in COL3A1 and is characterized by fragile vasculature and hollow organs, with a high risk of catastrophic events at a young age. During pregnancy and delivery, maternal mortality rates up until 25% have been reported. However, recent pedigree analysis reported a substantial lower pregnancy-related mortality rate of 4.9%. Here, we describe an extended vEDS family with multiple uneventful pregnancy outcomes. In the proband, a 37-year-old woman, DNA-analysis because of an asymptomatic iliac artery dissection revealed a pathogenic mutation in COL3A1 (c...
February 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28102328/qualitative-and-quantitative-analysis-with-a-novel-shear-wave-speed-imaging-for-differential-diagnosis-of-breast-lesions
#11
Yu-Ping Yang, Xiao-Hong Xu, Le-Hang Guo, Ya-Ping He, Dan Wang, Bo-Ji Liu, Chong-Ke Zhao, Bao-Ding Chen, Hui-Xiong Xu
To evaluate the diagnostic performance of a new two-dimensional shear wave speed (SWS) imaging (i.e. Toshiba shear wave elastography, T-SWE) in differential diagnosis of breast lesions. 225 pathologically confirmed breast lesions in 218 patients were subject to conventional ultrasound and T-SWE examinations. The mean, standard deviation and ratio of SWS values (m/s) and elastic modulus (KPa) on T-SWE were computed. Besides, the 2D elastic images were classified into four color patterns. The area under the receiver operating characteristic (AUROC) curve analysis was performed to evaluate the diagnostic performance of T-SWE in differentiation of breast lesions...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28101917/imaging-in-gynecological-disease-clinical-and-ultrasound-features-of-invasive-and-non-invasive-malignant-serous-ovarian-tumors
#12
F Moro, C Baima Poma, G F Zannoni, A Vidal Urbinati, T Pasciuto, M Ludovisi, M C Moruzzi, S Carinelli, D Franchi, G Scambia, A C Testa
OBJECTIVES: To describe clinical and ultrasound features of different subclasses of malignant serous ovarian tumors according to the WHO 2014 classification. METHODS: Patients with a histological diagnosis of borderline (BOT), non-invasive and invasive low grade serous carcinomas (LGSC) and high grade serous carcinoma (HGSC), who had undergone preoperative ultrasound examination, were retrospectively identified from two ultrasound centers. The masses were described using the terms of the International Ovarian Tumor Analysis group...
January 19, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28101352/shear-wave-elastography-and-contrast-enhanced-ultrasonography-in-the-diagnosis-of-thyroid-malignant-nodules
#13
Mei Chen, Ke-Qin Zhang, You-Feng Xu, Sheng-Min Zhang, Yong Cao, Wei-Qun Sun
The aim of the present study was to evaluate the value of shear wave elastography (SWE) and contrast-enhanced ultrasonography (CEUS) in the diagnosis of thyroid malignant nodules. A total of 253 patients with 319 thyroid nodules were subjected to two-dimensional ultrasound (2DUS) and CEUS examinations prior to thyroidectomy between March, 2014 and December, 2015. Young's modulus value for each nodule on 2DUS and CEUS images were recorded. The sensitivity, specificity and accuracy of 2DUS, SWE and CEUS in the diagnosis of thyroid malignant nodules were assessed...
December 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28101349/clear-cell-carcinoma-of-the-lower-uterine-segment-a-case-report
#14
Yusuke Matoba, Iori Kisu, Keiko Saotome, Motoko Katayama, Makiko Taniguchi, Yumiko Miura, Taeko Goto, Nobumaru Hirao
Uterine carcinoma of the lower uterine segment (LUS) is a rare tumor that accounts for 3-3.5% of cases of uterine malignant cancer. The tumor arises from the lower region of the uterine body through the upper region of the cervix. The present study reported a case of clear cell carcinoma that originated from the LUS. A 50-year-old woman visited a local hospital due to irregular vaginal bleeding. She was suspected to have a uterine tumor and was referred to Tachikawa Hospital (Tokyo, Japan). Transvaginal ultrasound and magnetic resonance imaging revealed a uterine tumor from the lower region of the uterine body through the upper region of the cervix...
December 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28100998/a-man-with-pancreatic-head-mass-lesion-on-endoscopic-ultrasound-and-granuloma-on-cytopathology
#15
Neda Rad, Arash Heidarnezhad, Setareh Soheili, Amir Houshang Mohammad-Alizadeh, Arash Nikmanesh
Primary pancreatic lymphoma is an unlikely malignancy accounting for less than 0.5% of pancreatic tumors. Clinical presentation is often nonspecific and may be clinically misdiagnosed as pancreatic adenocarcinoma. Here we present an Iranian case of primary pancreatic lymphoma in a 47-year-old male suffering from jaundice and 20% weight loss. Endoscopic ultrasound revealed a mixed echoic mass lesion at the head of pancreas. The patient underwent endoscopic ultrasound-guided fine needle aspiration of solid pancreatic mass and histopathologic diagnosis revealed granuloma...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28100996/intrapancreatic-accessory-spleen-a-diagnosis-not-to-forget
#16
Susana Marques, Miguel Bispo, Lariño Noia
A 69-year-old male patient was incidentally diagnosed with a 5-mm lesion in the pancreatic tail by endoscopic ultrasound (EUS). After contrast-enhanced EUS and EUS-elastography, all imaging features were highly suggestive of a benign pancreatic solid lesion such as an intrapancreatic accessory spleen (IPAS) or a benign neuroendocrine tumor. Interposition of the splenic artery precluded EUS-guided fine-needle aspiration (FNA). When an asymptomatic pancreatic mass is detected, IPAS diagnosis should be considered, and, if EUS-FNA is infeasible, contrast-enhanced EUS and EUS-elastography are useful tools to differentiate a pancreatic benign lesion as IPAS from a malignancy, with avoidance of unnecessary surgery...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28099332/lung-ultrasound-for-the-diagnosis-of-pneumonia-in-adults-a-meta-analysis
#17
Ling Long, Hao-Tian Zhao, Zhi-Yang Zhang, Guang-Ying Wang, He-Ling Zhao
BACKGROUND: Pneumonia is a common and serious infectious disease that can cause high mortality. The role of lung ultrasound (LUS) in the diagnosis of pneumonia is becoming more and more important. METHODS: In the present study, we collected existing evidence regarding the use of LUS to diagnose pneumonia in adults and conducted a systematic review to summarize the technique's diagnostic accuracy. We specifically searched the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, and Embase databases and retrieved outcome data to evaluate the efficacy of LUS for the diagnosis of pneumonia compared with chest radiography or chest computed tomography...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28099302/comparison-of-ultrasound-and-mri-for-the-diagnosis-of-glenohumeral-dysplasia-in-brachial-plexus-birth-palsy
#18
Kenneth W Donohue, Kevin J Little, John P Gaughan, Scott H Kozin, Brian D Norton, Dan A Zlotolow
BACKGROUND: In this study, we investigated the agreement between measurements made on ultrasound and those made on magnetic resonance imaging (MRI) in the assessment of glenohumeral dysplasia resulting from brachial plexus birth palsy. METHODS: Thirty-nine patients (14 male and 25 female) with brachial plexus birth palsy were evaluated at 2 tertiary care centers. All patients underwent ultrasonography and MRI for suspected glenohumeral dysplasia. Studies were obtained at an average of 2 months apart (range, 0 to 6 months)...
January 18, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28099260/differentiation-of-pancreatic-masses-via-endoscopic-ultrasound-strain-ratio-elastography-using-adjacent-pancreatic-tissue-as-the-reference
#19
Nadan Rustemović, Mirjana Kalauz, Katja Grubelić Ravić, Hrvoje Iveković, Branko Bilić, Zvonimir Ostojić, Dalibor Opačić, Iva Ledinsky, Matea Majerović, Ana Višnjić
OBJECTIVES: The aims of this study were to evaluate diagnostic value of endoscopic ultrasound strain ratio elastography in patients with focal pancreatic masses and to determine the cutoff value between the pancreatic malignancies and inflammatory pancreatic masses using reference areas different than those used by other investigators. METHODS: In a prospective single-center study, strain ratio was measured in patients with pancreatic masses. After the diagnosis was established, statistical analysis was used to compare the group with pancreatic malignancies to the one with inflammatory masses...
January 18, 2017: Pancreas
https://www.readbyqxmd.com/read/28099256/diagnosis-of-chronic-pancreatitis-incorporating-endosonographic-features-demographics-and-behavioral-risk
#20
Linda S Lee, Ying P Tabak, Vivek Kadiyala, Xiaowu Sun, Shadeah Suleiman, Richard S Johannes, Peter A Banks, Darwin L Conwell
OBJECTIVES: Diagnosing chronic pancreatitis remains challenging. Endoscopic ultrasound (EUS) is utilized to evaluate pancreatic disease. Abnormal pancreas function test is considered the "nonhistologic" criterion standard for chronic pancreatitis. We derived a prediction model for abnormal endoscopic pancreatic function test (ePFT) by enriching EUS findings with patient demographic and pancreatitis behavioral risk characteristics. METHODS: Demographics, behavioral risk characteristics, EUS findings, and peak bicarbonate results were collected from patients evaluated for pancreatic disease...
January 18, 2017: Pancreas
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