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https://www.readbyqxmd.com/read/30110109/characterization-of-communication-disorders-according-to-the-categories-of-the-international-classification-of-functioning-disability-and-health-children-and-youth-icf-cy
#1
Marina Garcia de Souza Borges, Adriane Mesquita de Medeiros, Stela Maris Aguiar Lemos
PURPOSE: Characterize the performance of outpatients regarding aspects of communication disorders according to the categories of the International Classification of Functioning, Disability and Health - Children and Youth Version (ICF-CY). METHODS: This is a descriptive, observational study based on a retrospective analysis of secondary data collected at a Speech-language Pathology outpatient clinic of the public health network, from records of patients aged 5-16 years, evaluated between 2010 and 2014...
August 13, 2018: CoDAS
https://www.readbyqxmd.com/read/30109711/are-guidelines-for-measurement-of-quality-of-life-contrary-to-patient-centred-care
#2
Timothy Disher, Louis Beaubien, Marsha Campbell-Yeo
AIMS: A discussion of how quality adjusted life years are used to inform resource allocation decisions and highlight how assumptions underpinning the measurement of quality of life are contrary to principles of patient-centred care. BACKGROUND: Cost-effectiveness analyses can provide influential guidance for health resource allocation, particularly in the context of a budget constrained public health insurance plan. Most national economic guideline bodies recommend that quality adjusted life-year weights for cost-effectiveness analysis be elicited indirectly (public preferences)...
August 14, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/30105210/performance-of-a-whole-body-human-dust-inhalation-challenge-exposure-chamber
#3
Luis F Pieretti, Yehia Y Hammad
Background: Evaluation of the performance of a whole-body human dust exposure chamber is presented in this report. Methods: The volume of the chamber is 2.13 m3 and it is operated at a flow rate of 1.0 m3 /min. Makeup and exhaust air were filtered. A Wright Dust Feeder was used to generate fly ash, the testing agent. An elutriator was used to maintain particles in the respirable range. A Rupprecht and Patashnick PM-10 TEOM, a direct reading instrument, was used to monitor particle concentration...
2018: Toxicology Reports
https://www.readbyqxmd.com/read/30102885/morphological-genetic-and-biological-characterisation-of-a-novel-alphabaculovirus-isolated-from-cryptophlebia-peltastica-lepidoptera-tortricidae
#4
Tamryn Marsberg, Michael D Jukes, Martyna Krejmer-Rabalska, Lukasz Rabalski, Caroline M Knox, Sean D Moore, Martin P Hill, Boguslaw Szewczyk
Cryptophlebia peltastica is an agricultural pest of litchis and macadamias in South Africa with phytosanitary status for certain markets. Current control methods rely on chemical, cultural and classical biological control. However, a microbial control option has not been developed. An Alphabaculovirus from C. peltastica was recovered from a laboratory reared colony and morphologically characterised by transmission electron microscopy (TEM). Analysis of occlusion bodies indicated a single NPV (SNPV) varying in size from 421 to 1263 nm...
August 10, 2018: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/30094551/letrozole-concentration-is-associated-with-cyp2a6-variation-but-not-with-arthralgia-in-patients-with-breast-cancer
#5
Adrienne E Borrie, Rhiannon V Rose, Yun-Hee Choi, Francisco E Perera, Nancy Read, Tracy Sexton, Michael Lock, Theodore A Vandenberg, Karin Hahn, Robert Dinniwell, Jawaid Younus, Diane Logan, Kylea Potvin, Brian Yaremko, Edward Yu, John Lenehan, Stephen Welch, Rachel F Tyndale, Wendy A Teft, Richard B Kim
PURPOSE: The aromatase inhibitor (AI) letrozole is a first-line drug in the adjuvant treatment of breast cancer in postmenopausal women. Adherence to AI therapy, including letrozole, remains problematic due to the development of debilitating AI-induced arthralgia. Letrozole is metabolized in the liver by CYP2A6. It remains unknown if plasma letrozole levels or CYP2A6 genetic variation is associated with the development of arthralgia. METHODS: We enrolled 126 female breast cancer patients initiated on letrozole therapy and prospectively collected blood samples at baseline and two follow-up time points to determine letrozole plasma concentrations and CYP2A6 genotype...
August 9, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/30093855/gender-differences-in-processing-fearful-and-angry-body-expressions
#6
Zhenhong He, Zhenli Liu, Ju Wang, Dandan Zhang
Previous studies have demonstrated differential perception of body expressions between males and females. However, only two recent studies (Kret et al., 2011; Krüger et al., 2013) explored the interaction effect between observer gender and subject gender, and it remains unclear whether this interaction between the two gender factors is gender-congruent (i.e., better recognition of emotions expressed by subjects of the same gender) or gender-incongruent (i.e., better recognition of emotions expressed by subjects of the opposite gender)...
2018: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/30081835/small-rna-seq-analysis-of-single-porcine-blastocysts-revealed-that-maternal-estradiol-17beta-exposure-does-not-affect-mirna-isoform-isomir-expression
#7
Jochen T Bick, Veronika L Flöter, Mark D Robinson, Stefan Bauersachs, Susanne E Ulbrich
BACKGROUND: The expression of microRNAs (miRNAs) is essential for the proper development of the mammalian embryo. A maternal exposure to endocrine disrupting chemicals during preimplantation bears the potential for transgenerational inheritance of disease through the epigenetic perturbation of the developing embryo. A comprehensive assembly of embryo-specific miRNAs and respective isoforms (isomiR) is lacking to date. We aimed at revealing the sex-specific miRNA expression profile of single porcine blastocysts developing in gilts orally exposed to exogenous estradiol-17 (E2)...
August 6, 2018: BMC Genomics
https://www.readbyqxmd.com/read/30075533/epidemiological-and-clinical-implications-of-blood-pressure-measured-in-seated-versus-supine-position
#8
Ernest Privšek, Margareta Hellgren, Lennart Råstam, Ulf Lindblad, Bledar Daka
The evidence concerning how posture influences blood pressure is not consistent. The aim of this cross-sectional study was to consider the clinical and epidemiological implications of blood pressure measured in seated versus supine position, and to investigate the impact of age, sex, body mass index (BMI), and diabetes on these differences.This study included 1298 individuals (mean age 58.6 ± 11.8 years) from the Vara-Skövde cohort at the 10 years' follow-up visit in 2014. Physical examination included blood pressure measurements in seated and supine position...
August 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30071642/an-adaptive-weighted-knn-positioning-method-based-on-omnidirectional-fingerprint-database-and-twice-affinity-propagation-clustering
#9
Jingxue Bi, Yunjia Wang, Xin Li, Hongxia Qi, Hongji Cao, Shenglei Xu
The human body has a great influence on Wi-Fi signal power. A fixed K value leads to localization errors for the K-nearest neighbor (KNN) algorithm. To address these problems, we present an adaptive weighted KNN positioning method based on an omnidirectional fingerprint database (ODFD) and twice affinity propagation clustering. Firstly, an OFPD is proposed to alleviate body's sheltering impact on signal, which includes position, orientation and the sequence of mean received signal strength (RSS) at each reference point (RP)...
August 1, 2018: Sensors
https://www.readbyqxmd.com/read/30063227/barm-and-balticmicrobedb-a-reference-metagenome-and-interface-to-meta-omic-data-for-the-baltic-sea
#10
Johannes Alneberg, John Sundh, Christin Bennke, Sara Beier, Daniel Lundin, Luisa W Hugerth, Jarone Pinhassi, Veljo Kisand, Lasse Riemann, Klaus Jürgens, Matthias Labrenz, Anders F Andersson
The Baltic Sea is one of the world's largest brackish water bodies and is characterised by pronounced physicochemical gradients where microbes are the main biogeochemical catalysts. Meta-omic methods provide rich information on the composition of, and activities within, microbial ecosystems, but are computationally heavy to perform. We here present the Baltic Sea Reference Metagenome (BARM), complete with annotated genes to facilitate further studies with much less computational effort. The assembly is constructed using 2...
July 31, 2018: Scientific Data
https://www.readbyqxmd.com/read/30060267/investigation-and-evaluation-of-potential-aerosol-release-by-maquet-getinge-heater-cooler-units-used-during-cardiac-surgery
#11
Sebastian Schwandtner, Herwig Reichel, Lutz Jatzwauk, Klaus Ehrhard Matschke
BACKGROUND:  Heater-Cooler units (HCUs) supply tempered water through blood heat exchangers and through warming/cooling blankets to control the body temperature of heart surgery patients. Bacteria which potentially colonize the stored water may escape from the tank into the environment and are carried by the device's cooling air exhaust into the sterile field and finally may infect open chest heart surgery patients. Reports from several countries are connecting the infection of open chest heart surgery patients to airborne transmitted Mycobacteria chimaera which were found in the water of heater-cooler devices...
July 30, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/30057806/prevalence-of-primary-hypertension-and-risk-factors-in-grade-xii-learners-in-kwazulu-natal-south-africa
#12
Rajendra Bhimma, Elaene Naicker, Verena Gounden, Louansha Nandlal, Cathy Connolly, Sudesh Hariparshad
Hypertension in childhood leads to hypertension in adult life, the strongest risk factor being obesity. This study determined the prevalence of primary hypertension and its risk factors in Grade XII learners in KwaZulu-Natal, South Africa, from March 2016 to June 2017. Weight, height, body mass index (BMI), random finger prick cholesterol and glucose, and spot urine for an albumin : creatinine ratio were measured. An average of three separate blood pressure readings taken was at least 5 minutes apart. Five hundred and sixty-four learners had weight, height, and BMI; 536 had random blood glucose; and 545 had cholesterol and random spot urine albumin : creatinine ratios measured...
2018: International Journal of Hypertension
https://www.readbyqxmd.com/read/30057577/a-single-vibrionales-16s-rrna-oligotype-dominates-the-intestinal-microbiome-in-two-geographically-separated-atlantic-cod-populations
#13
Even S Riiser, Thomas H A Haverkamp, Ørnulf Borgan, Kjetill S Jakobsen, Sissel Jentoft, Bastiaan Star
Atlantic cod ( Gadus morhua ) provides an interesting species for the study of host-microbe interactions because it lacks the MHC II complex that is involved in the presentation of extracellular pathogens. Nonetheless, little is known about the diversity of its microbiome in natural populations. Here, we use high-throughput sequencing of the 16S rRNA V4 region, amplified with the primer design of the Earth Microbiome Project (EMP), to investigate the microbial composition in gut content and mucosa of 22 adult individuals from two coastal populations in Norway, located 470 km apart...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/30056547/local-and-whole-body-staging-in-patients-with-primary-breast-cancer-a-comparison-of-one-step-to-two-step-staging-utilizing-18-f-fdg-pet-mri
#14
Julian Kirchner, Johannes Grueneisen, Ole Martin, Mark Oehmigen, Harald H Quick, Ann-Kathrin Bittner, Oliver Hoffmann, Marc Ingenwerth, Onofrio Antonio Catalano, Philipp Heusch, Christian Buchbender, Michael Forsting, Gerald Antoch, Ken Herrmann, Lale Umutlu
OBJECTIVES: The purpose of this study was to compare the diagnostic value of a one-step to a two-step staging algorithm utilizing 18 F-FDG PET/MRI in breast cancer patients. METHODS: A total of 38 patients (37 females and one male, mean age 57 ± 10 years; range 31-78 years) with newly diagnosed, histopathologically proven breast cancer were prospectively enrolled in this trial. All PET/MRI examinations were assessed for local tumor burden and metastatic spread in two separate reading sessions: (1) One-step algorithm comprising supine whole-body 18 F-FDG PET/MRI, and (2) Two-step algorithm comprising a dedicated prone 18 F-FDG breast PET/MRI and supine whole-body 18 F-FDG PET/MRI...
July 28, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30049626/misclassification-of-blood-pressure-of-vietnamese-adults-when-only-a-single-measurement-is-used
#15
Nga T T Tran, Christopher L Blizzard, Khue N Luong, Ngoc L V Truong, Bao Q Tran, Panagiota Veloudi, Petr Otahal, Mark Nelson, Costan Magnussen, Seana Gall, Tan V Bui, Velandai Srikanth, Thuy B Au, Son T Ha, Hai N Phung, Mai H Tran, Michele Callisaya, James Sharman
A single clinic measurement of blood pressure (BP) may be common in low- and middle-income countries because of limited medical resources. This study aimed to examine the potential misclassification error when only one BP measurement is used. Participants (n = 14,706, 53.5% females) aged 25-64 years were selected by multistage stratified cluster sampling from eight provinces, each representing one of the eight geographical regions of Vietnam. Measurements were made using the World Health Organization STEPS protocols...
June 30, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30041376/identification-and-characterization-of-heat-shock-protein-90-hsp90-in-the-hard-coral-acropora-tenuis-in-response-to-irgarol-1051
#16
Hiroshi Ishibashi, Seigo Minamide, Ichiro Takeuchi
To elucidate the effects of the herbicide Irgarol 1051 on the gene expression of heat shock protein 90 (HSP90) in hard corals, we isolated a full-length cDNA encoding HSP90 from Acropora tenuis, which has a deduced open reading frame of 732-amino acid residues with a predicted molecular mass of 84.5 kDa. The amino acid sequence of A. tenuis HSP90 showed a high degree of similarity with the hermatypic-coral HSP90 families. After a 7-d exposure to 1 or 10 μg/L of Irgarol, the body colours of corals in the 10 μg/L treatment group were significantly whiter (bleached), whereas no such effects were observed in the corals in the 1 μg/L treatment group...
August 2018: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/30040950/anterior-scleral-thickness-changes-with-accommodation-in-myopes-and-emmetropes
#17
Emily C Woodman-Pieterse, Scott A Read, Michael J Collins, David Alonso-Caneiro
Although a range of changes in anterior segment structures have been documented to occur during accommodation, the quantification of changes in the structure of the anterior sclera during the accommodation process in human subjects has yet to be examined. This study therefore aimed to investigate the presence of short-term changes in anterior scleral thickness associated with accommodation in young adult myopic and emmetropic subjects. Anterior scleral thickness was measured in 20 myopes and 20 emmetropes (mean age 21 ± 2 years) during various accommodation demands (0, 3 and 6 D) with anterior segment optical coherence tomography (AS-OCT)...
July 21, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/30036655/transcriptome-analysis-for-identification-of-candidate-genes-related-to-sex-determination-and-growth-in-charybdis-japonica
#18
Fangrui Lou, Tianyan Yang, Zhiqiang Han, Tianxiang Gao
Charybdis japonica is an important cultured crab in China and it exhibits sex differences in their growth. Growth is an important economic trait that is controlled by many genes. In order to discover the growth-related regulatory mechanisms, whole-body transcriptomic sequencing and comparative analyses in different genders of C. japonica were conducted based on Illumina RNA-seq technology. In the present study, we obtained 62,879,204 and 60,226,334 clean reads in female and male libraries, respectively. 25,000,000 clean reads of every library were randomly selected and compared with Nt database to examine the possible contamination...
July 20, 2018: Gene
https://www.readbyqxmd.com/read/30035241/evaluation-of-a-digital-diabetes-prevention-program-adapted-for-the-medicaid-population-study-design-and-methods-for-a-non-randomized-controlled-trial
#19
Sue E Kim, Cynthia M Castro Sweet, Eliza Gibson, Erica N Madero, Barbara Rubino, Janina Morrison, Debra Rosen, Wendy Imberg, Michael R Cousineau
Previous studies have shown that lifestyle modification can successfully prevent or delay development of type 2 diabetes. This trial aimed to test if an underserved, low-income population would engage in a digital diabetes prevention program and successfully achieve lifestyle changes to reduce their risk of type 2 diabetes. Participants were recruited from three health care facilities serving low-income populations. The inclusion criteria were: a recent blood test indicating prediabetes, body mass index (BMI) > 24 kg/m2 , age 18-75 years, not pregnant, not insured, Medicaid insured or Medicaid-eligible, internet or smartphone access, and comfort reading and writing in English or Spanish...
June 2018: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/30031243/resolving-host-microbe-interactions-in-the-gut-the-promise-of-in-vitro-models-to-complement-in-vivo-research
#20
REVIEW
Wilmes Paul, Calatayud Marta, Van de Wiele Tom
While animal models remain essential for inferring causality, they exhibit important limitations, which restrict the direct translation of findings into new approaches aimed at steering host-microbe interactions for the improvement of human health. Different in vitro models have therefore been developed which incorporate human cell types and microbiota. By virtue of their intricate designs, these models result in human and microbial read-outs reflective of in vivo gut physiology, and present important alternatives to animal models...
July 18, 2018: Current Opinion in Microbiology
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