Philipp Arndt, Christian Chahem, Michael Luchtmann, Jan-Niklas Kuschel, Daniel Behme, Malte Pfister, Jens Neumann, Michael Görtler, Marc Dörner, Marc Pawlitzki, Robin Jansen, Sven G Meuth, Stefan Vielhaber, Solveig Henneicke, Stefanie Schreiber
BACKGROUND: Sporadic cerebral small-vessel disease (CSVD), i.e., hypertensive arteriopathy (HA) and cerebral amyloid angiopathy (CAA), is the main cause of spontaneous intracerebral hemorrhage (ICH). Nevertheless, a substantial portion of ICH cases arises from non-CSVD etiologies, such as trauma, vascular malformations, and brain tumors. While studies compared HA- and CAA-related ICH, non-CSVD etiologies were excluded from these comparisons and are consequently underexamined with regard to additional factors contributing to increased bleeding risk beyond their main pathology...
2024: Frontiers in Neurology