keyword
https://read.qxmd.com/read/38596258/editorial-regenerative-biologics-for-musculoskeletal-injuries
#1
EDITORIAL
Ashim Gupta, Anish G Potty, Nicola Maffulli
No abstract text is available yet for this article.
2024: Front Pain Res (Lausanne)
https://read.qxmd.com/read/38299138/new-technique-of-reverse-bone-grafting-with-core-decompression-and-enriching-with-regenerative-medicine-techniques-for-grade-2-and-grade-3-avascular-necrosis-of-both-hips
#2
Saksham Goyal, Sandeep Shrivastav, Ratnakar Ambade, Aditya Pundkar, Ashutosh Lohiya
Early avascular necrosis (AVN) of the hip poses a significant clinical challenge, requiring prompt recognition and intervention to mitigate long-term complications. A case report describing a 30-year-old man with bilateral hip AVN is presented here. In addition, to reverse bone grafting and core decompression of both hips, the patient had platelet-rich plasma (PRP) infiltration in the right hip and bone marrow aspirate concentrate (BMAC) infiltration in the left hip. This method attempted to stop the disease's development and promote hip regeneration in both...
December 2023: Curēus
https://read.qxmd.com/read/38299047/reporting-bias-is-highly-prevalent-in-systematic-reviews-and-meta-analyses-of-platelet-rich-plasma-injections-for-hip-osteoarthritis
#3
REVIEW
Daniel Kim, Bryan S Bashrum, Jacob L Kotlier, Cory K Mayfield, Ashley A Thompson, Maya Abu-Zahra, Mina Hwang, Ioanna K Bolia, Frank A Petrigliano, Joseph N Liu
PURPOSE: To describe the incidence and types of spin in systematic reviews of platelet-rich plasma (PRP) injections for hip osteoarthritis (OA) and to determine whether patterns in study characteristics could be identified among studies with identifiable spin. METHODS: The PubMed, Scopus, and SPORTDiscus databases were queried. Inclusion criteria were systematic reviews or meta-analyses that included an assessment of intra-articular PRP injections as a stand-alone treatment for hip OA...
February 2024: Arthroscopy, sports medicine, and rehabilitation
https://read.qxmd.com/read/38273397/regenerative-therapies-for-femoral-head-necrosis-in-the-past-two-decades-a-systematic-review-and-network-meta-analysis
#4
REVIEW
Xiaole Wang, Liyou Hu, Bo Wei, Jian Wang, Decai Hou, Xiaolei Deng
BACKGROUND: Regenerative techniques combined with core decompression (CD) are commonly used to treat osteonecrosis of the femoral head (ONFH). However, no consensus exists on regeneration therapy combined with CD that performs optimally. Therefore, we evaluated six regenerative therapies combined with CD treatment using a Bayesian network meta-analysis (NMA). METHODS: We searched PubMed, Embase, Cochrane Library, and Web of Science databases. Six common regeneration techniques were categorized into the following groups with CD as the control group: (1) autologous bone graft (ABG), (2) autologous bone graft combined with bone marrow aspirate concentrate (ABG + BMAC), (3) bone marrow aspirate concentrate (BMAC), (4) free vascular autologous bone graft (FVBG), (5) expanded mesenchymal stem cells (MSCs), and (6) platelet-rich plasma (PRP)...
January 25, 2024: Stem Cell Research & Therapy
https://read.qxmd.com/read/38181110/core-decompression-combined-with-platelet-rich-plasma-augmented-bone-grafting-for-femur-head-necrosis-a-systematic-review-and-meta-analysis
#5
JOURNAL ARTICLE
Bo Zhu, Shengyi Feng, Xuejia Li, Bo Li, Jianmin Li
BACKGROUND: The clinical potential of biologic augmentation in core decompression and bone grafting for femoral head necrosis is widely acknowledged, with platelet-rich plasma (PRP) being a frequently employed biologic adjunct. However, its clinical application is not standardized, and high-level evidence is lacking. This study aimed to evaluate the efficacy and safety of core decompression and bone grafting combined with PRP for femur head necrosis. METHODS: Several databases were systematically retrieved for randomized controlled trials comparing core decompression and bone grafting combined with or without PRP...
January 4, 2024: International Journal of Surgery
https://read.qxmd.com/read/38094334/retracted-effect-of-nha-coated-femoral-stem-prosthesis-combined-with-platelet-rich-plasma-in-hemi-hip-replacement-of-femoral-neck-fracture-in-the-elderly
#6
Computational And Mathematical Methods In Medicine
[This retracts the article DOI: 10.1155/2022/9089084.].
2023: Computational and Mathematical Methods in Medicine
https://read.qxmd.com/read/38077288/safety-and-feasibility-of-locoregional-platelet-rich-plasma-injection-for-iliopsoas-impingement-after-total-hip-arthroplasty-a-phase-1-prospective-observational-study
#7
JOURNAL ARTICLE
Yasuhiro Homma, Sayuri Uchino, Masashi Nagao, Takanori Wakayama, Shin Fukusato, Tomonori Baba, Taiji Watari, Koju Hayashi, Yoshitomo Saita, Muneaki Ishijima
INTRODUCTION: Although numerous studies have reported outcomes with various conservative approaches for the iliopsoas impingement after total hip arthroplasty (THA), reports on the use of locoregional autologous platelet rich plasma (PRP) injections for the iliopsoas impingement after THA are lacking. This phase 1 study therefore aimed to investigate the safety and feasibility of locoregional PRP injection for iliopsoas impingement after THA. MATERIALS AND METHODS: Patients diagnosed with iliopsoas impingement after THA who met the criteria for participation (symptoms persisting for more than 3 months, aged 20 years or older, and unable to receive non-steroidal analgesic or anti-inflammatory drugs) were eligible to participate in this clinical study...
March 2024: Regenerative Therapy
https://read.qxmd.com/read/38048139/management-of-greater-trochanteric-pain-syndrome-after-total-hip-arthroplasty-practice-patterns-and-surgeon-attitudes
#8
JOURNAL ARTICLE
Daniel E Axelrod, Seper Ekhtiari, Mitchell J Winemaker, Justin de Beer, Thomas J Wood
INTRODUCTION: Greater trochanteric pain syndrome (GTPS) or trochanteric bursitis is described as pain on the lateral side of the hip that does not involve the hip joint and can be elicited clinically by palpation over the greater trochanter. To date, there remains no consensus on clinical guidelines for either diagnosis or management of GTPS. METHODS: To understand the practice patterns, beliefs, and attitudes relating to the management of GTPS after total hip arthroplasty, a survey was developed and completed by Canadian arthroplasty surgeons...
December 1, 2023: Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews
https://read.qxmd.com/read/38034028/patient-outcomes-are-not-improved-by-platelet-rich-plasma-injection-onto-the-capsule-at-the-time-of-closure-during-hip-arthroscopy-for-femoroacetabular-impingement-syndrome
#9
JOURNAL ARTICLE
S Craig Morris, William T Haselman, Michael B Banffy
PURPOSE: To determine the effect of platelet-rich plasma (PRP) injection onto the capsule at time of closure on outcomes of patients undergoing hip arthroscopy for femoroacetabular impingement syndrome. METHODS: Patients who underwent hip arthroscopy between January 2014 and December 2021 were retrospectively identified. The first cohort included patients who received PRP injection onto the capsule following capsular closure at the conclusion of the case. The second cohort did not receive PRP...
December 2023: Arthroscopy, sports medicine, and rehabilitation
https://read.qxmd.com/read/38021456/treatment-of-osteonecrosis-of-the-femoral-head-with-multiple-drilling-and-bone-marrow-mesenchymal-stem-cells-expanded-ex-vivo-plus-biomolecules-derived-from-platelet-rich-plasma-a-case-report
#10
Maria C Canencio Salgado, Omar Amado Pico, Claudia L Sossa, Martha Ligia Arango-Rodríguez
Osteonecrosis of the femoral head (ONFH) is a debilitating condition that predominantly affects young individuals, resulting in disability and involving significant healthcare costs. Therefore, it is crucial to develop an effective therapeutic strategy to treat this debilitating disease. In this context, autologous bone marrow-derived mesenchymal stem cells (auto-BM-MSCs) have emerged as a promising approach for treating ONFH. In this case report, we applied this therapy to a patient with ONFH and evaluated both its safety and therapeutic benefits...
2023: American Journal of Stem Cells
https://read.qxmd.com/read/37940869/is-there-structural-change-on-mri-in-gluteal-tendinopathy-after-treatment-single-outcome-measure-extension-of-an-rct
#11
RANDOMIZED CONTROLLED TRIAL
Georgia Carney, Jane Fitzpatrick
BACKGROUND: The etiology of tendinopathy remains controversial and it is unknown whether degenerative structural changes in tendinopathies are reversible. HYPOTHESIS: There will be no structural change on magnetic resonance imaging (MRI) taken > 2-years after treatment for gluteal tendinopathy. STUDY DESIGN: Extension of a single site, double-blind, prospective randomized-controlled trial to analyze the additional outcome measure; MRI changes...
November 8, 2023: BMC Medical Imaging
https://read.qxmd.com/read/37937095/non-operative-treatment-options-for-osteoarthritis-in-the-hip
#12
REVIEW
Erin Nicholas, Jennifer Cheng, Peter J Moley
With the increased disability associated with osteoarthritis (OA) progression, and the significant socioeconomic burden of joint replacement surgeries, there is a need for more reliable conservative treatments for patients presenting with hip OA. Most studies of OA treatments involve the knee. We conducted a literature search and reviewed non-operative hip OA treatment recommendations by the Osteoarthritis Research Society International, the American College of Rheumatology, American Academy of Orthopedic Surgeons, and European Alliance of Associations for Rheumatology, as well as Cochrane Reviews...
November 2023: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://read.qxmd.com/read/37906291/orthobiologics-as-an-adjunct-in-treatment-of-femoroacetabular-impingement-syndrome-cell-based-therapies-facilitate-improved-postoperative-outcomes-in-the-setting-of-acetabular-chondral-lesions-a-systematic-review
#13
REVIEW
Tracy George, Andrew J Curley, Sheema K Saeed, Benjamin D Kuhns, Ali Parsa, Benjamin G Domb
PURPOSE: To evaluate studies utilizing orthobiologics in the management of femoroacetabular impingement syndrome (FAIS) to (1) assess the indications for usage, and (2) analyze patient-reported outcome measures (PROM) following treatment. It was hypothesized that orthobiologics would (1) be utilized for symptomatic FAIS in the setting of labral or chondral pathology, and (2) improve PROM at most recent follow-up. METHODS: The Pubmed, Ovid Medline, Cochrane, and Web of Science databases were searched for clinical studies evaluating orthobiologics [hyaluronic acid (HA), platelet-rich plasma (PRP), or cell-based therapy (CBT) for treatment of FAIS...
October 31, 2023: Knee Surgery, Sports Traumatology, Arthroscopy
https://read.qxmd.com/read/37905161/comparing-intra-articular-platelet-rich-plasma-with-hyaluronic-acid-for-the-treatment-of-hip-osteoarthritis-a-systematic-review-and-meta-analysis
#14
REVIEW
Hembashima G Sambe, Mohamed Yasir, Ruzhual K Man, Amaresh Gogikar, Ankita Nanda, Lakshmi Sai Niharika Janga, Pousette Hamid
Hip osteoarthritis (HOA), a prevalent condition among those aged 55 years and above, is a significant cause of joint pain and functional impairment and it contributes to the overall burden of chronic pain experienced by the elderly population. While platelet-rich plasma (PRP) and hyaluronic acid (HA) injections have emerged as innovative therapeutic approaches for managing osteoarthritis, their effectiveness in HOA remains a subject of contention. Therefore, the objective of this review was to assess the efficacy of PRP versus HA in terms of pain relief and functional outcomes for the management of HOA...
October 2023: Curēus
https://read.qxmd.com/read/37893971/a-preliminary-report-on-the-combined-effect-of-intra-articular-platelet-rich-plasma-injections-and-photobiomodulation-in-canine-osteoarthritis
#15
JOURNAL ARTICLE
J C Alves, Ana Santos, L Miguel Carreira
Osteoarthritis (OA) is highly prevalent in the canine population. Due to the multiple dimensions of the disease, a multimodal approach is usually favored by clinicians. To evaluate the combined treatment with intra-articular platelet-rich plasma (PRP) and photobiomodulation in dogs with bilateral hip OA, thirty dogs were assigned to a PRP group (PRPG, n = 10), a photobiomodulation group (PBMTG, n = 10), or a combined therapies group (PRP+PBMTG, n = 10). The PRPG received two intra-articular administrations of platelet-rich plasma 14 days apart...
October 18, 2023: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/37486253/adductor-longus-and-brevis-lesion-in-an-amateur-soccer-player-platelet-rich-plasma-and-multifractioned-hyaluronic-acid-injections-to-enhance-clinical-recovery
#16
JOURNAL ARTICLE
Silvana Giannini, Sebastiano Vasta, Arrigo Giombini, Chiara Fossati, Ugo Riba, Giuseppe Massazza, Rocco Papalia, Fabio Pigozzi
Groin pain is a common issue in athletes, with a particularly high incidence in male soccer players. Adductor muscles are the most involved site of the groin, accounting for up to one-fourth of muscle injuries of that region. Physical therapy and rehabilitation programs for adductor-related groin pain using active exercises are effective in getting athletes back to sport. However, the return-to-play time varies according to the injury severity. Minor lesions can recover in 1-2 weeks, while severer injuries require 8-12 weeks...
December 2023: Journal of Sports Medicine and Physical Fitness
https://read.qxmd.com/read/37441691/efficacy-and-safety-of-platelet-rich-plasma-injections-for-the-treatment-of-osteoarthritis-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#17
Yongqing Xiong, Cheng Gong, Xumiao Peng, Xianlei Liu, Xinda Su, Xi Tao, Ying Li, Youliang Wen, Wei Li
BACKGROUND: In recent years, platelet-rich plasma (PRP) injections for osteoarthritis (OA) have been widely promoted in clinical practice, but their effectiveness is controversial. Therefore, we conducted a meta-analysis of relevant randomized controlled trials (RCTs) to determine the efficacy and safety of PRP injections for the treatment of OA. METHODS: We searched databases including Embase, Web of Science, Medline, PubMed, and the Cochrane Library for relevant studies...
2023: Frontiers in Medicine
https://read.qxmd.com/read/37396144/allogenic-platelet-rich-plasma-for-treatment-of-knee-and-hip-osteoarthritis
#18
REVIEW
Ashim Gupta, Anish G Potty, Nicola Maffulli
Osteoarthritis (OA) induces tremendous amounts of stress and financial burden on patients and healthcare systems worldwide. Current treatments have limitations and do not address the etiopathogenetic cause of OA. Regenerative medicine may circumvent limitations posed by traditional modalities and relies on the utilization of biologics including platelet-rich plasma (PRP). Several peer-reviewed studies have documented the safety and efficacy of autologous PRP in mitigating symptoms in knee and hip OA patients...
2023: Front Pain Res (Lausanne)
https://read.qxmd.com/read/37147073/editorial-commentary-hip-arthroscopy-in-patients-with-early-degeneration-who-receive-intra-articular-bone-marrow-aspirate-concentrate-can-achieve-outcomes-similar-to-nonarthritic-patients
#19
EDITORIAL
Matthew J Hartwell, Alan L Zhang
The management of patients with early joint degeneration is challenging. In this setting, biologic interventions, from platelet-rich plasma to bone marrow aspirate concentrate (BMAC) to hyaluronic acid, may be beneficial. Recent research, with 2-year follow-up, shows that patients with early degenerative changes (Tönnis grade 1 or 2) who received intra-articular injection of BMAC after hip arthroscopy procedure had improvements in outcomes similar to nonarthritic patients (Tönnis 0) with symptomatic labral tears who underwent arthroscopy and did not receive BMAC...
June 2023: Arthroscopy
https://read.qxmd.com/read/37138690/computer-assisted-and-hip-arthroscopy-for-avascular-necrosis-of-the-femoral-head-with-femoroacetabular-impingement
#20
JOURNAL ARTICLE
Yu-Mei Wu, Yi-Lin Xiong, Wei-Jie Liu, Hang Tang, Yi-Fan Xiao, Shu-Guang Gao
Avascular necrosis of the femoral head with femoroacetabular impingement is a disabling disease. Without early treatment and intervention, its further development will even lead to hip osteoarthritis and hip dysfunction. This technical note aims to introduce a computer-assisted precise core decompression of the femoral head, followed by injection of platelet-rich plasma and bone marrow aspirate concentrate. Then, the autologous ipsilateral iliac bone is transplanted to the core decompression area. Thereafter, under hip arthroscopy, the injured glenoid lip of the hip joint is repaired, and the cam deformity of the femoral head/neck junction is polished and formed...
April 2023: Arthroscopy Techniques
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