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Vishal Khandelwal, Ullal Anand Nayak, Prathibha Anand Nayak, Nupur Ninawe
Background Orofacial trauma is one of the most prevailing oral health problems among the children. This study aimed to assess the prevalence and distribution of traumatic injuries and to correlate the causes, specific age groups, socio-economic status, occlusal relationship and ascertain the percentage of those seeking the treatment among school children in Indore (Madhya Pradesh, India). Materials and methods Five thousand school going children aged between 3 and 17 years belonging to different zones of Indore were randomly selected and divided into three age groups, Group I - 3-5 years; Group II - 6-11 years and Group III - 12-17 years...
November 6, 2018: International Journal of Adolescent Medicine and Health
Ramesh Rajendran, Ajitha Pandi, Aparna Ramchary, Hemalatha Thiagarajan, Jithendra Panneerselvam, Ayyadurai Niraikulam, Gowthaman Marichetti Kuppuswami, Kamini Numbi Ramudu
Urease is a potent metalloenzyme with diverse applications. This paper describes the scale up and purification of an extracellular urease from Arthrobacter creatinolyticus MTCC 5604. The urease production was scaled-up in 3.7 L and 20 L fermentor. A maximum activity of 27 and 27.8 U/mL and a productivity of 0.90 and 0.99 U/mL/h were obtained at 30 h and 28 h in 3.7 and 20 L fermentor, respectively. Urease was purified to homogeneity with 49.85-fold purification by gel filtration and anion exchange chromatography with a yield of 36% and a specific activity of 1044...
October 29, 2018: Molecular Biology Reports
Areen Sen, Ratul Saha, Kuppuswamy Sivakumar, Punyasloke Bhadury
Modern benthic foraminiferal assemblages are instrumental in providing information regarding changes in relative sea level as well as prevailing environmental conditions in marine environments. Marginal marine environments are coastal environments that are in most cases characterized by high influx of terrestrially originated nutrients. Inventorizing of modern benthic foraminiferal assemblages from such habitats can act as biotic indicators of water quality variations along with any changes in relative sea level...
June 27, 2018: Zootaxa
Kuppuswami Jayashree, Md Yasir, Gandhipuram Periyasamy Senthilkumar, K Ramesh Babu, Vadivelan Mehalingam, Palani Selvam Mohanraj
AIMS: Diabetic Retinopathy (DR) is the leading cause of vision loss in the working age population. Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1), are molecules involved in extracellular tissue matrix remodelling. They are implicated in the loss of retinal tissue integrity, a major cause of DR, that leads to retinal tissue degradation and apoptosis. This study is therefore, conducted to compare the serum levels of MMP-9 and TIMP-1 in T2DM patients without and with retinopathy, and to evaluate their association with the severity of DR...
November 2018: Diabetes & Metabolic Syndrome
Samuel M Greer, Johannes McKay, Kathryn M Gramigna, Christine M Thomas, Sebastian A Stoian, Stephen Hill
Direct metal-metal bonding of two distinct first-row transition metals remains relatively unexplored compared to their second- and third-row heterobimetallic counterparts. Herein, a recently reported Fe-V triply bonded species, [V( i PrNPPh2 )3 FeI] (1; Kuppuswamy, S.; Powers, T. M.; Krogman, J. P.; Bezpalko, M. W.; Foxman, B. M.; Thomas, C. M. Vanadium-iron complexes featuring metal-metal multiple bonds. Chem. Sci. 2013, 4, 3557-3565), is investigated using high-frequency electron paramagnetic resonance, field- and temperature-dependent 57 Fe nuclear gamma resonance (Mössbauer) spectroscopy, and high-field electron-electron double resonance detected nuclear magnetic resonance...
May 21, 2018: Inorganic Chemistry
Elayaraja Kolanthai, Pugazhendhi Abinaya Sindu, Deepak Kumar Khajuria, Sarath Chandra Veerla, Dhandapani Kuppuswamy, Luiz Henrique Catalani, D Roy Mahapatra
Developing a biodegradable scaffold remains a major challenge in bone tissue engineering. This study was aimed at developing novel alginate-chitosan-collagen (SA-CS-Col)-based composite scaffolds consisting of graphene oxide (GO) to enrich porous structures, elicited by the freeze-drying technique. To characterize porosity, water absorption, and compressive modulus, GO scaffolds (SA-CS-Col-GO) were prepared with and without Ca2+ -mediated crosslinking (chemical crosslinking) and analyzed using Raman, Fourier transform infrared (FTIR), X-ray diffraction (XRD), and scanning electron microscopy techniques...
April 18, 2018: ACS Applied Materials & Interfaces
Ganga Anil Kumar, Kuppuswamy Subramaniam
Pairing of homologous chromosomes is essential for genetic recombination during gametogenesis. In many organisms, chromosome ends are attached to cytoplasmic dynein, and dynein-driven chromosomal movements facilitate the pairing process. Factors that promote or control the cytoskeletal tethering of chromosomes are largely unknown. Here, we show that the conserved RNA-binding protein PUF-8 facilitates the tethering and pairing processes in the C. elegans germline by promoting proteasome activity. We have isolated a hypomorphic allele of pas-1 , which encodes a proteasome core subunit, and find that the homologous chromosomes fail to pair in the puf-8; pas-1 double mutant due to failure of chromosome tethering...
March 29, 2018: Development
Kuppuswamy Arumugam, Malathy Selvachandran, Antony Obanda, Mohamed C Shaw, Perumalreddy Chandrasekaran, Sonya L Caston Good, Joel T Mague, Stephen Sproules, James P Donahue
Compounds of the type [(S2 C2 R2 )M(μ-tpbz)M(S2 C2 R2 )] (R = CN, Me, Ph, p-anisyl; M = Ni, Pd, Pt; tpbz = 1,2,4,5-tetrakis(diphenylphosphino)benzene) have been prepared by transmetalation with [(S2 C2 R2 )SnR'2 ] reagents, by direct displacement of dithiolene ligand from [M(S2 C2 R2 )2 ] with 0.5 equiv of tpbz, or by salt metathesis using Na2 [S2 C2 (CN)2 ] in conjunction with X2 M(μ-tpbz)MX2 (X = halide). X-ray crystallography reveals a range of topologies (undulating, chair, bowed) for the (S2 C2 )M(P2 C6 P2 )M(S2 C2 ) core...
April 2, 2018: Inorganic Chemistry
Jiguang Rao, Kuppuswamy Porsezian, Jingsong He, Thambithurai Kanna
General semi-rational solutions of an integrable multi-component (2+1)-dimensional long-wave-short-wave resonance interaction system comprising multiple short waves and a single long wave are obtained by employing the bilinear method. These solutions describe the interactions between various types of solutions, including line rogue waves, lumps, breathers and dark solitons. We only focus on the dynamical behaviours of the interactions between lumps and dark solitons in this paper. Our detailed study reveals two different types of excitation phenomena: fusion and fission...
January 2018: Proceedings. Mathematical, Physical, and Engineering Sciences
Thiagarajan Hemalatha, Periyathambi Prabu, Dharmalingam Nandagopal Gunadharini, Marichetti Kuppuswami Gowthaman
Bionanocomposites fabricated using metal nanoparticles serve a wide range of biomedical applications viz., site targeted drug delivery, imaging etc. Theranostics emerge as an important field of science, which focuses on the use of single entity for both disease diagnosis and treatment. The present work aimed at designing a multifunctional nanocomposite comprising of iron/gold hybrid nanoparticles, coated with oleyl chitosan and conjugated with methotrexate. The HR-TEM images revealed the spherical nature of the composite, while it's nontoxic and biocompatible property was proved by the MTT assay in NIH 3T3 cells and hemolysis assay...
June 2018: International Journal of Biological Macromolecules
Vibha Sanjay Bafna, Tanvi Ajay Bafna, Abhilasha Sampagar, Sunita Raman Rupavataram
OBJECTIVES: To evaluate the impact of pediatric malignancies on quality of life (QOL) and psychological status of parents and to correlate it with well-matched controls and socioeconomic status. METHODS: A prospective comparative cross-sectional study was conducted. Seventy parents of children diagnosed with pediatric malignancies within the last three months were enrolled in the study group (SG) and 50 matched parents of healthy children as the control group (CG)...
September 2018: Indian Journal of Pediatrics
Balaji Kuppuswamy, Kirubakaran Davis, Raj Sahajanandan, Manickam Ponniah
OBJECTIVE: The objective of the study is to compare the myocardial protective effects of isoflurane with propofol in patients undergoing elective coronary artery bypass surgery on cardiopulmonary bypass (CPB), the cardio protection been assessed by changes in N-terminal brain natriuretic peptide (NT proBNP). Methodology and Design: This study is designed as a participant blinded, prospective randomized clinical trial. SETTING: Christian Medical College Hospital, Vellore, India...
January 2018: Annals of Cardiac Anaesthesia
Muna Bhende, Sharan Shetty, Mohana Kuppuswamy Parthasarathy, S Ramya
Optical coherence tomography is a quick, non invasive and reproducible imaging tool for macular lesions and has become an essential part of retina practice. This review address the common protocols for imaging the macula, basics of image interpretation, features of common macular disorders with clues to differentiate mimickers and an introduction to choroidal imaging . It includes case examples and also a practical algorithm for interpretation.
January 2018: Indian Journal of Ophthalmology
Chris Joseph, Subramaniam Kuppuswamy, Vincent M Lynch, Michael J Rose
Herein we report the synthesis, X-ray structure, and characterization of the title pentairon (molybdo)carbido cluster. The reaction of the pentairon (μ5 -carbido) dianion [Fe5 (μ6 -C)(μ2 -CO)2 (CO)12 ]2- (1) with [Mo(CO)3 (chpt)] (chpt = cycloheptatriene) forms the heterohexanuclear cluster [K(benzo-18-crown-6)]2 [Fe5 Mo(μ6 -C)(μ2 -CO)3 (CO)14 ] (2). The dianion exhibits a Fe5 Mo(μ6 -C) core structure supported by three bridging (νCO = 1788 cm-1 ) and terminal (νCO = 1943 cm-1 ) CO ligands. Cluster 2 provides the selective reduction of diphenylacetylene to cis-diphenylethylene via a spectroscopically observed cluster-hydride intermediate (1 H NMR: δ -26)...
January 2, 2018: Inorganic Chemistry
Kalpana Balakrishnan, Santu Ghosh, Gurusamy Thangavel, Sankar Sambandam, Krishnendu Mukhopadhyay, Naveen Puttaswamy, Arulselvan Sadasivam, Padmavathi Ramaswamy, Priscilla Johnson, Rajarajeswari Kuppuswamy, Durairaj Natesan, Uma Maheshwari, Amudha Natarajan, Gayathri Rajendran, Rengaraj Ramasami, Sathish Madhav, Saraswathy Manivannan, Srinivasan Nargunanadan, Srinivasan Natarajan, Sudhakar Saidam, Moumita Chakraborty, Lingeswari Balakrishnan, Vijayalakshmi Thanasekaraan
BACKGROUND: Exposure to PM2.5 (fine particulate matter <less than 2.5µm in aerodynamic diameter) related to ambient and household air pollution has been associated with low birthweight. Few of these studies, however, have been conducted in high exposure settings that are commonly encountered in low and middle income countries (LMICs). OBJECTIVES: We examined whether PM2.5 exposures during pregnancy were associated with birthweight in an integrated rural-urban, mother-child cohort in the state of Tamil Nadu, India...
February 2018: Environmental Research
Rahul Sharma
Some of the facets of the Kuppuswamy's socioeconomic status scale sometimes create confusion and require explanation on how to classify, and need some minor updates to bring the scale up-to-date. This article provides a revised scale that allows for the real-time update of the scale.
October 15, 2017: Indian Pediatrics
Jasmine Khubchandani, Apurv Soni, Nisha Fahey, Nitin Raithatha, Anusha Prabhakaran, Nancy Byatt, Tiffany A Moore Simas, Ajay Phatak, Milagros Rosal, Somashekhar Nimbalkar, Jeroan J Allison
The aim of this study is to examine the relationship of caste and class with perceived discrimination among pregnant women from rural western India. A cross-sectional survey was administered to 170 pregnant women in rural Gujarat, India, who were enrolled in a longitudinal cohort study. The Everyday Discrimination Scale and the Experiences of Discrimination questionnaires were used to assess perceived discrimination and response to discrimination. Based on self-report caste, women were classified into three categories with increasing historical disadvantage: General, Other Backward Castes (OBC), and Scheduled Caste or Tribes (SC/ST)...
April 2018: Archives of Women's Mental Health
William De Doncker, Robert Dantzer, Heidi Ormstad, Annapoorna Kuppuswamy
Poststroke fatigue is a debilitating symptom and is poorly understood. Here we summarise molecular, behavioural and neurophysiological changes related to poststroke fatigue and put forward potential theories for mechanistic understanding of poststroke fatigue.
March 2018: Journal of Neurology, Neurosurgery, and Psychiatry
Annapoorna Kuppuswamy
No abstract text is available yet for this article.
August 1, 2017: Brain: a Journal of Neurology
Jiguang Rao, Kuppuswamy Porsezian, Jingsong He
General dark solitons and mixed solutions consisting of dark solitons and breathers for the third-type Davey-Stewartson (DS-III) equation are derived by employing the bilinear method. By introducing the two differential operators, semi-rational solutions consisting of rogue waves, breathers, and solitons are generated. These semi-rational solutions are given in terms of determinants whose matrix elements have simple algebraic expressions. Under suitable parametric conditions, we derive general rogue wave solutions expressed in terms of rational functions...
August 2017: Chaos
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