keyword
https://read.qxmd.com/read/38406018/neonatal-skull-depression-the-role-of-cranial-ultrasound
#1
André Assunção, Filipa Flor-de-Lima, Josué Pereira, Daniela Pinto
Nontraumatic congenital neonatal skull depression is a rare condition resulting from external forces shaping the fetal skull. Typically, newborns are asymptomatic, and, usually, the condition resolves in a few months with no need for intervention. However, many newborns undergo a CT scan, an ionizing technique, to check for fractures or intracranial lesions. We report a case of congenital skull depression without neurological deficits, managed conservatively through clinical monitoring and ultrasound.
January 2024: Curēus
https://read.qxmd.com/read/38347123/quantified-retrospective-biomonitoring-of-fetal-and-infant-elemental-exposure-using-la-icp-ms-analysis-of-deciduous-dentin-in-three-contrasting-human-cohorts
#2
JOURNAL ARTICLE
T Punshon, Julia A Bauer, Margaret R Karagas, Modupe O Coker, Marc G Weisskopf, Joseph J Mangano, Felicitas B Bidlack, Matthew N Barr, Brian P Jackson
BACKGROUND: Spatial elemental analysis of deciduous tooth dentin combined with odontochronological estimates can provide an early life (in utero to ~2 years of age) history of inorganic element exposure and status. OBJECTIVE: To demonstrate the importance of data normalization to a certified reference material to enable between-study comparisons, using populations with assumed contrasting elemental exposures. METHODS: We used laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) of dentin to derive a history of elemental composition from three distinct cohort studies: a present day rural cohort, (the New Hampshire Birth Cohort Study (NHBCS; N = 154)), an historical cohort from an urban area (1958-1970), (the St...
February 12, 2024: Journal of Exposure Science & Environmental Epidemiology
https://read.qxmd.com/read/38272284/intrapartum-cardiotocography-with-simultaneous-maternal-heart-rate-registration-improves-neonatal-outcome
#3
JOURNAL ARTICLE
Mikko Tarvonen, Janne Markkanen, Ville Tuppurainen, Riina Jernman, Vedran Stefanovic, Sture Andersson
BACKGROUND: Intrapartum cardiotocographic monitoring of fetal heart rate by abdominal external ultrasound transducer without simultaneous maternal heart rate recording has been associated with increased risk of early neonatal death and other asphyxia-related neonatal outcomes. It is unclear, however, whether this increase in risk is independently associated with fetal surveillance method or is attributable to other factors. OBJECTIVES: In a large retrospective cohort of deliveries, the aim of the present study was to compare different fetal surveillance methods and their association with adverse short-term and long-term fetal and neonatal outcomes...
January 21, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38256403/effect-of-pethidine-injection-on-the-duration-of-labor-and-pregnancy-outcomes-a-retrospective-cohort-study
#4
JOURNAL ARTICLE
Eun Byeol Cho, Hyun Joo Chae, Jung Min Ryu, Hyo Jin Lee, Seong Yeon Hong, Jin Young Bae
Background and Objectives : Long and ineffective labor causes hardships for mothers and doctors and increases the rate of cesarean sections and medical comorbidities. Several factors contribute to effective and less painful labor, including maternal age, parity, fetal characteristics, and the medications or procedures that obstetricians use for labor. We aimed to study the factors that affect labor duration and identify those that make labor more effective. Materials and Methods : This retrospective study included 141 patients who underwent normal vaginal deliveries at the Daegu Catholic University Medical Center between April 2013 and April 2022...
January 12, 2024: Medicina
https://read.qxmd.com/read/38106566/retrospective-analysis-of-pregnancy-outcomes-following-external-cephalic-version-for-breech-presentation
#5
JOURNAL ARTICLE
Jun Han, Shuai Wang, Mei Ding
OBJECTIVE: We explored the feasibility and safety of external cephalic version (ECV) for cases of breech presentation. METHODS: We retrospectively analyzed data from 158 singleton pregnant women with breech presentation at 36 weeks gestation, admitted to Guangzhou Hospital of Integrated Traditional and Western Medicine from January 2018 to March 2022. 42 underwent ECV, categorized as the ECV group, while 116 without ECV comprised the control group. Systematic collection and evaluation of pregnancy outcomes were conducted for both groups...
2023: International Journal of Women's Health
https://read.qxmd.com/read/38104394/pregnancy-management-of-ivf-et-pregnancies-in-a-patient-with-classical-21-hydroxylase-deficiency-a-case-report-and-review-of-the-literature
#6
REVIEW
Junxin Yu, Sha Lu, Lingya Fang, Nisile Kakongoma, Wensheng Hu
OBJECTIVE: To report a rare case of a woman with classical 21-hydroxylase deficiency who twice had singleton pregnancies with live births after in vitro fertilization and embryo transfer (IVF-ET). DESIGN: Case report and literature review. PATIENT: A 35-year-old woman with classical 21-hydroxylase deficiency underwent external genital plastic surgery during adolescence and achieved second pregnancy after IVF-ET with long-term glucocorticoid replacement therapy...
December 7, 2023: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/38028032/external-fetus-in-fetu-presenting-in-the-second-trimester-a-case-report-and-literature-review
#7
Ying Zhu, Le Xu, Rajluxmee Beejadhursing, Suhua Chen
Fetus in fetu (FIF) is a rare congenital anomaly that originates from various sites of the host twin's body. The clinical manifestations of FIF are diverse and the location and size of FIF indicate the degree of threat, which may directly affect the prognosis. A 33-year-old woman presented at the hospital with an abdominal mass in her fetus. Prenatal ultrasound observed that mass included soft tissue, bone-like structures, and fluid. Immature cartilage, nerve tissue, muscle tissue, and glands in the parasitic fetus without signs of neoplastic lesions were reported by histological examination...
November 2023: Clinical Case Reports
https://read.qxmd.com/read/37945341/why-is-safety-in-intrapartum-electronic-fetal-monitoring-so-hard-a-qualitative-study-combining-human-factors-ergonomics-and-social-science-analysis
#8
JOURNAL ARTICLE
Guillaume Lamé, Elisa Giulia Liberati, Aneurin Canham, Jenni Burt, Lisa Hinton, Tim Draycott, Cathy Winter, Francesca Helen Dakin, Natalie Richards, Lucy Miller, Janet Willars, Mary Dixon-Woods
BACKGROUND: Problems in intrapartum electronic fetal monitoring with cardiotocography (CTG) remain a major area of preventable harm. Poor understanding of the range of influences on safety may have hindered improvement. Taking an interdisciplinary perspective, we sought to characterise the everyday practice of CTG monitoring and the work systems within which it takes place, with the goal of identifying potential sources of risk. METHODS: Human factors/ergonomics (HF/E) experts and social scientists conducted 325 hours of observations and 23 interviews in three maternity units in the UK, focusing on how CTG tasks were undertaken, the influences on this work and the cultural and organisational features of work settings...
November 9, 2023: BMJ Quality & Safety
https://read.qxmd.com/read/37806861/-intrahepatic-cholestasis-of-pregnancy-french-college-of-obstetricians-and-gynecologists-guidelines-for-clinical-practice
#9
L Sentilhes, M-V Sénat, H Bouchghoul, P Delorme, D Gallot, C Garabedian, H Madar, N Sananès, F Perrotin, T Schmitz
OBJECTIVE: To identify strategies for reducing neonatal and maternal morbidity associated with intrahepatic cholestasis pregnancy (ICP). MATERIAL AND METHODS: The quality of evidence of the literature was assessed following the GRADE methodology with questions formulated in the PICO format (Patients, Intervention, Comparison, Outcome) and outcomes defined a priori and classified according to their importance. An extensive bibliographic search was performed on PubMed, Cochrane, EMBASE and Google Scholar databases...
October 6, 2023: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/37484942/dexamethasone-affects-human-fetal-adrenal-steroidogenesis-and-subsequent-acth-response-in-an-ex-vivo-culture-model
#10
JOURNAL ARTICLE
Cecilie Melau, Berta Gayete Mor, Malene Lundgaard Riis, John E Nielsen, Eva Dreisler, Kasper Aaboe, Pia Tutein Brenøe, Lea Langhoff Thuesen, Kristine Juul Hare, Rod T Mitchell, Hanne Frederiksen, Anders Juul, Anne Jørgensen
INTRODUCTION: Administration of dexamethasone (DEX) has been used experimentally to suppress androgenization of external genitalia in 46,XX fetuses with congenital adrenal hyperplasia. Despite this, the prenatal biological mechanism-of-action of DEX on fetal development is not known. This study aimed to examine direct effects of DEX on human fetal adrenal (HFA) steroidogenic activity including possible effects on the subsequent response to ACTH-stimulation. METHODS: Human fetal adrenal (HFA) tissue from 30 fetuses (1st trimester) were cultured ex vivo with A) DEX (10 µm) for 14 days, or B) DEX (10 µm) for 10 days followed by ACTH (1 nM) for 4 days...
2023: Frontiers in Endocrinology
https://read.qxmd.com/read/37211139/noninvasive-preeclampsia-prediction-using-plasma-cell-free-rna-signatures
#11
JOURNAL ARTICLE
Si Zhou, Jie Li, Wenzhi Yang, Penghao Xue, Yanning Yin, Yunfang Wang, Peirun Tian, Huanhuan Peng, Hui Jiang, Wenqiu Xu, Shang Huang, Rui Zhang, Fengxiang Wei, Hai-Xi Sun, Jianguo Zhang, Lijian Zhao
BACKGROUND: Preeclampsia, especially preterm preeclampsia and early-onset preeclampsia, is a life-threating pregnancy disorder, and the heterogeneity and complexity of preeclampsia make it difficult to predict risk and to develop treatments. Plasma cell-free RNA carries unique information from human tissue and may be useful for noninvasive monitoring of maternal, placental, and fetal dynamics during pregnancy. OBJECTIVE: This study aimed to investigate various RNA biotypes associated with preeclampsia in plasma and to develop classifiers to predict preterm preeclampsia and early-onset preeclampsia before diagnosis...
November 2023: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/37201795/the-fetal-scalp-electrode-shortage-is-an-urgent-patient-safety-issue
#12
JOURNAL ARTICLE
Daniel J Kiely, Lawrence W Oppenheimer
There is currently a shortage of fetal scalp electrodes due to a recent recall because of concerns about breakage of the electrode tip with possible injury to the neonate. While the recall is presumably intended to improve safety, the resulting shortage poses risks to patients due to inadequate fetal heart rate monitoring in cases where an adequate signal cannot be obtained with external fetal monitoring and/or when maternal heart rate artefact cannot be resolved by repositioning of transducers and application of a maternal pulse oximeter...
May 16, 2023: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/37164494/assessment-of-uterine-contractions-in-labor-and-delivery
#13
REVIEW
Hadar Rosen, Yariv Yogev
Normal labor and delivery are dependent on the presence of regular and effective contractions of the uterine myometrium. The mechanisms responsible for the initiation and maintenance of adequate and synchronized uterine activity that are necessary for labor and delivery result from a complex interplay of hormonal, mechanical, and electrical factors that have not yet been fully elucidated. Monitoring uterine activity during term labor and in suspected preterm labor is an important component of obstetrical care because cases of inadequate and excessive uterine activity can be associated with substantial maternal and neonatal morbidity and mortality...
May 2023: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/36921720/racial-bias-in-cesarean-decision-making
#14
JOURNAL ARTICLE
Sara E Edwards, Quetzal A Class, Catherine E Ford, Tamika A Alexander, Jonah D Fleisher
BACKGROUND: Continuous external fetal monitoring showing category II fetal heart tracing is a frequent indication for cesarean birth in the United States, despite its somewhat subjective interpretation. Black patients have higher rates of cesarean birth, as well as higher rates for this indication. Racial bias in clinical decision-making has been demonstrated throughout medicine, including in obstetrics. OBJECTIVE: We sought to examine if racial bias is present in providers' decisions about cesarean birth due to category II fetal heart tracings...
March 13, 2023: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/36658532/associations-between-gestational-weight-gain-and-adverse-neonatal-outcomes-a-comparison-between-the-us-and-the-chinese-guidelines-in-chinese-women-with-twin-pregnancies
#15
JOURNAL ARTICLE
Feng Liang, Yun Lin, Ling Li, Chuanzi Yang, Xiaojun Li, Kuanrong Li
BACKGROUND: Appropriate gestational weight gain (GWG) is essential for maternal and fetal health. For twin pregnancies among Caucasian women, the Institute of Medicine (IOM) guidelines can be used to monitor and guide GWG. We aimed to externally validate and compare the IOM guidelines and the recently released guidelines for Chinese women with twin pregnancies regarding the applicability of their recommendations on total GWG (TGWG). METHOD: A retrospective cohort study of 1534 women who were aged 18-45 years and gave birth to twins at ≥ 26 gestational weeks between October 2016 and June 2020 was conducted in Guangzhou, China...
January 19, 2023: BMC Public Health
https://read.qxmd.com/read/36647548/predelivery-placenta-associated-biomarkers-and-computerized-intrapartum-fetal-heart-rate-patterns
#16
JOURNAL ARTICLE
Sophie Bowe, Birgitte Mitlid-Mork, Jon M Gran, Sonia Distante, Christopher W G Redman, Anne Cathrine Staff, Antoniya Georgieva, Meryam Sugulle
BACKGROUND: Increasing syncytiotrophoblast stress in term and postdate placentas is reflected by increasing antiangiogenic dysregulation in the maternal circulation, with low "proangiogenic" placental growth factor concentrations and increased "antiangiogenic" soluble fms-like tyrosine kinase-1 concentrations. Imbalances in these placenta-associated proteins are associated with intrapartum fetal compromise and adverse pregnancy and delivery outcome. Cardiotocography is widely used to assess fetal well-being during labor, but it is insufficient on its own for predicting adverse neonatal outcome...
February 2023: AJOG global reports
https://read.qxmd.com/read/36588461/uterine-dose-conversion-coefficients-for-external-photons-for-the-taiwanese-pregnant-women
#17
JOURNAL ARTICLE
Hao-Ting Chang, Rui-Wen Liu, Fang-Yuh Hsu, Ching-Han Hsu, Yu-Ying Lin
The Oak Ridge National Laboratory (ORNL) phantoms based on data of Caucasians have been widely used for fetal dosimetry. However, there are differences in body size during pregnancy among Taiwanese and Caucasians. In this study, the uterine dose conversion coefficients (DCCs) of Taiwanese pregnant women were evaluated to facilitate the use of it to estimate the possible uterine dose (usually regarded as fetal dose) of pregnant Taiwanese women during radiation practice or medical exposures. The uterine DCCs in this study were calculated based on the established Taiwanese pregnancy voxel phantoms, and were compared with the uterine DCCs of the International Commission on Radiological Protection...
January 2, 2023: Radiation Protection Dosimetry
https://read.qxmd.com/read/36435756/neonatal-eyelid-penetration-from-insertion-of-a-fetal-scalp-electrode-a-case-report
#18
JOURNAL ARTICLE
Brian T Cheng, Kelly D Laurenti, Sudhi P Kurup
BACKGROUND: A fetal scalp electrode (FSE), first described by Edward Hon in 1967, is an intrapartum monitoring device embedded directly into the fetal scalp for an accurate measure of fetal heart rate. Though use of an FSE is generally safe, complications can occur from misplacement, including ophthalmic injury. CASE PRESENTATION: Patient was a 28-year-old G6P5006 who presented for induction of labor at 39 weeks due to asymptomatic bilateral pulmonary embolism...
November 26, 2022: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/36336386/imaging-of-trauma-in-pregnancy
#19
REVIEW
Devang Odedra, Vincent M Mellnick, Michael N Patlas
A pregnant patient with acute trauma is not commonly encountered by clinicians and radiologists. A multidisciplinary approach is key. Although radiography and ultrasound examination are frequently used modalities in the setting of maternal-fetal trauma, the fear of radiation should not preclude from carrying out a thorough diagnostic workup of the patient with a computed tomography scan. MRI mainly serves as a problem solving and follow-up modality. After stabilizing the mother, fetal well-being should be assessed with external fetal monitoring and a dedicated obstetric ultrasound examination...
January 2023: Radiologic Clinics of North America
https://read.qxmd.com/read/36246050/anesthesia-for-fetal-operative-procedures-a-systematic-review
#20
REVIEW
Miriam Duci, Rebecca Pulvirenti, Francesco Fascetti Leon, Irma Capolupo, Paola Veronese, Piergiorgio Gamba, Costanza Tognon
OBJECTIVE: The anesthetic management of fetal operative procedures (FOP) is a highly debated topic. Literature on fetal pain perception and response to external stimuli is rapidly expanding. Nonetheless, there is no consensus on the fetal consciousness nor on the instruments to measure pain levels. As a result, no guidelines or clinical recommendations on anesthesia modality during FOP are available. This systematic literature review aimed to collect the available knowledge on the most common fetal interventions, and summarize the reported outcomes for each anesthetic approach...
2022: Front Pain Res (Lausanne)
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